ECSP10010430A - Ciertas Entidades Químicas, Composiciones y Procedimientos - Google Patents
Ciertas Entidades Químicas, Composiciones y ProcedimientosInfo
- Publication number
- ECSP10010430A ECSP10010430A EC2010010430A ECSP10010430A ECSP10010430A EC SP10010430 A ECSP10010430 A EC SP10010430A EC 2010010430 A EC2010010430 A EC 2010010430A EC SP10010430 A ECSP10010430 A EC SP10010430A EC SP10010430 A ECSP10010430 A EC SP10010430A
- Authority
- EC
- Ecuador
- Prior art keywords
- skeletal
- muscle
- chemical entities
- certain chemical
- procedures
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 150000005829 chemical entities Chemical class 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 210000003205 muscle Anatomy 0.000 abstract 2
- 102000007469 Actins Human genes 0.000 abstract 1
- 108010085238 Actins Proteins 0.000 abstract 1
- 208000036119 Frailty Diseases 0.000 abstract 1
- 206010022562 Intermittent claudication Diseases 0.000 abstract 1
- 108090000362 Lymphotoxin-beta Proteins 0.000 abstract 1
- 208000001145 Metabolic Syndrome Diseases 0.000 abstract 1
- 206010028289 Muscle atrophy Diseases 0.000 abstract 1
- 102000003505 Myosin Human genes 0.000 abstract 1
- 108060008487 Myosin Proteins 0.000 abstract 1
- 102000001708 Protein Isoforms Human genes 0.000 abstract 1
- 108010029485 Protein Isoforms Proteins 0.000 abstract 1
- 102000005937 Tropomyosin Human genes 0.000 abstract 1
- 108010030743 Tropomyosin Proteins 0.000 abstract 1
- 102000013534 Troponin C Human genes 0.000 abstract 1
- 102000013394 Troponin I Human genes 0.000 abstract 1
- 108010065729 Troponin I Proteins 0.000 abstract 1
- 102000004987 Troponin T Human genes 0.000 abstract 1
- 108090001108 Troponin T Proteins 0.000 abstract 1
- 201000000690 abdominal obesity-metabolic syndrome Diseases 0.000 abstract 1
- 206010003549 asthenia Diseases 0.000 abstract 1
- 208000024980 claudication Diseases 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000020763 muscle atrophy Effects 0.000 abstract 1
- 201000000585 muscular atrophy Diseases 0.000 abstract 1
- 208000018360 neuromuscular disease Diseases 0.000 abstract 1
- 210000002235 sarcomere Anatomy 0.000 abstract 1
- 210000002027 skeletal muscle Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
Abstract
Se proveen ciertas entidades químicas y métodos de uso para modular la miosina esquelética, la actina del esqueleto, la tropomiosina del esqueleto, la troponina C del esqueleto, la troponina I esquelética, troponina T esquelética y el músculo esquelético, incluyendo fragmentos y las isoformas de la misma, así como el sarcómero esquelético, y métodos de uso en el tratamiento de los trastornos neuromusculares, condiciones que tienen pérdida de masa muscular, la claudicación, la fragilidad, el síndrome metabólico, la atrofia muscular asociada con el desuso, y la fatiga muscular, y otras indicaciones.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2606708P | 2008-02-04 | 2008-02-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP10010430A true ECSP10010430A (es) | 2011-02-28 |
Family
ID=40952391
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2010010430A ECSP10010430A (es) | 2008-02-04 | 2010-08-27 | Ciertas Entidades Químicas, Composiciones y Procedimientos |
| EC2010010432A ECSP10010432A (es) | 2008-02-04 | 2010-08-30 | Método para la mejora de la recuperación de hidrocarburos pesados |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2010010432A ECSP10010432A (es) | 2008-02-04 | 2010-08-30 | Método para la mejora de la recuperación de hidrocarburos pesados |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US7989469B2 (es) |
| EP (1) | EP2244711A4 (es) |
| JP (1) | JP2011510985A (es) |
| KR (1) | KR20100119773A (es) |
| CN (1) | CN101983061A (es) |
| AR (1) | AR072242A1 (es) |
| AU (1) | AU2009210787A1 (es) |
| BR (1) | BRPI0907502A2 (es) |
| CA (1) | CA2713864A1 (es) |
| CL (1) | CL2009000246A1 (es) |
| CO (1) | CO6290673A2 (es) |
| EA (1) | EA201001224A1 (es) |
| EC (2) | ECSP10010430A (es) |
| IL (1) | IL207367A0 (es) |
| MX (1) | MX2010008518A (es) |
| TW (1) | TW200946524A (es) |
| WO (1) | WO2009099594A1 (es) |
| ZA (1) | ZA201005780B (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8299248B2 (en) | 2006-08-02 | 2012-10-30 | Cytokinetics, Incorporated | Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use |
| CA2713864A1 (en) * | 2008-02-04 | 2009-08-13 | Cytokinetics, Incorporated | Certain chemical entities, compositions and methods |
| CN102127070A (zh) | 2010-01-15 | 2011-07-20 | 山东轩竹医药科技有限公司 | 吡啶并环衍生物 |
| ES2547687T3 (es) * | 2011-07-09 | 2015-10-08 | Xuanzhu Pharma Co., Ltd. | Forma cristalina I de sal de un inhibidor de dipeptidil-peptidasa IV y procedimiento de preparación y uso de la misma |
| CN109316480A (zh) | 2011-07-13 | 2019-02-12 | 赛特凯恩蒂克公司 | 组合als疗法 |
| BR112014025251B1 (pt) * | 2012-04-11 | 2021-03-02 | Fady Malik | uso de um ativador de troponina de músculo esquelético e composição compreendendo o mesmo |
| LT3137622T (lt) | 2014-04-29 | 2022-04-25 | Cytokinetics, Inc. | Gyvybinio pajėgumo nykimo mažinimo būdai |
| TW201927738A (zh) * | 2017-12-14 | 2019-07-16 | 丹麥商Ｎｍｄ藥品公司 | 用於治療神經肌肉病症的化合物 |
| TWI794369B (zh) * | 2017-12-14 | 2023-03-01 | 丹麥商Ｎｍｄ藥品公司 | 用於治療神經肌肉病症的化合物 |
| EP3976612A4 (en) * | 2019-05-28 | 2023-04-26 | Mankind Pharma Ltd | NEW COMPOUNDS FOR INHIBITION OF JANUS KINASE 1 |
| US20240262821A1 (en) * | 2021-05-06 | 2024-08-08 | Exscientia Al Limited | PKC-Theta Modulators |
| CN118702622A (zh) * | 2024-08-30 | 2024-09-27 | 阜新达得利化工股份有限公司 | 一种3-溴-2-氰基吡啶的制备方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0206860D0 (en) * | 2002-03-22 | 2002-05-01 | Glaxo Group Ltd | Compounds |
| GB0212048D0 (en) * | 2002-05-24 | 2002-07-03 | Merck Sharp & Dohme | Therapeutic agents |
| US20040166137A1 (en) * | 2002-11-08 | 2004-08-26 | Lackey John William | Hetero-substituted benzimidazole compounds and antiviral uses thereof |
| EP1646614A4 (en) * | 2003-07-01 | 2008-09-10 | Merck & Co Inc | OPHTHALMIC COMPOSITIONS FOR THE TREATMENT OF OCCULAR HYPERTONIA |
| EP1694323A4 (en) * | 2003-12-19 | 2009-05-13 | Elixir Pharmaceuticals Inc | METHOD FOR TREATING A DISEASE |
| EP1715855A4 (en) * | 2004-01-29 | 2010-06-16 | Elixir Pharmaceuticals Inc | ANTIVIRAL DRUGS |
| WO2005108374A1 (en) | 2004-04-29 | 2005-11-17 | Fmc Corporation | Insecticidal diazole and triazole derivatives |
| GB0420719D0 (en) * | 2004-09-17 | 2004-10-20 | Addex Pharmaceuticals Sa | Novel allosteric modulators |
| WO2007078815A2 (en) * | 2005-12-16 | 2007-07-12 | Cytokinetics, Inc. | Certain chemical entities, compositions, and methods |
| US8227603B2 (en) * | 2006-08-01 | 2012-07-24 | Cytokinetics, Inc. | Modulating skeletal muscle |
| BRPI0714725B1 (pt) * | 2006-08-02 | 2021-05-25 | Cytokinetics, Inc | Entidade química, composição farmaceuticamente aceitável, e, uso de uma entidade química |
| ES2627352T3 (es) * | 2006-10-19 | 2017-07-27 | Signal Pharmaceuticals, Llc | Compuestos heteroarilo, sus composiciones y su uso como inhibidores de proteínas quinasas |
| CL2007002994A1 (es) * | 2006-10-19 | 2008-02-08 | Wyeth Corp | Compuestos derivados heterociclicos que contienen sulfamoilo, inhibidores de hsp90; composicion farmaceutica; y uso para el tratamiento del cancer, tal como cancer de mama, de colon y prostata, entre otros. |
| WO2008075007A1 (en) * | 2006-12-21 | 2008-06-26 | Cancer Research Technology Limited | Morpholino-substituted bicycloheteroaryl compounds and their use as anti cancer agents |
| US7851484B2 (en) * | 2007-03-30 | 2010-12-14 | Cytokinetics, Inc. | Certain chemical entities, compositions, and methods |
| US7998976B2 (en) * | 2008-02-04 | 2011-08-16 | Cytokinetics, Inc. | Certain chemical entities, compositions and methods |
| CA2713864A1 (en) * | 2008-02-04 | 2009-08-13 | Cytokinetics, Incorporated | Certain chemical entities, compositions and methods |
| CN102264743B (zh) | 2008-11-25 | 2015-02-11 | 罗彻斯特大学 | Mlk抑制剂及其使用方法 |
-
2009
- 2009-02-02 CA CA2713864A patent/CA2713864A1/en not_active Abandoned
- 2009-02-02 US US12/364,394 patent/US7989469B2/en not_active Expired - Fee Related
- 2009-02-02 MX MX2010008518A patent/MX2010008518A/es not_active Application Discontinuation
- 2009-02-02 AU AU2009210787A patent/AU2009210787A1/en not_active Abandoned
- 2009-02-02 CN CN2009801121602A patent/CN101983061A/zh active Pending
- 2009-02-02 EA EA201001224A patent/EA201001224A1/ru unknown
- 2009-02-02 EP EP09708594A patent/EP2244711A4/en not_active Withdrawn
- 2009-02-02 WO PCT/US2009/000686 patent/WO2009099594A1/en not_active Ceased
- 2009-02-02 BR BRPI0907502A patent/BRPI0907502A2/pt not_active Application Discontinuation
- 2009-02-02 JP JP2010545031A patent/JP2011510985A/ja not_active Withdrawn
- 2009-02-02 KR KR1020107018611A patent/KR20100119773A/ko not_active Withdrawn
- 2009-02-03 TW TW098103382A patent/TW200946524A/zh unknown
- 2009-02-04 CL CL2009000246A patent/CL2009000246A1/es unknown
- 2009-02-04 AR ARP090100372A patent/AR072242A1/es unknown
-
2010
- 2010-08-02 IL IL207367A patent/IL207367A0/en unknown
- 2010-08-13 ZA ZA2010/05780A patent/ZA201005780B/en unknown
- 2010-08-27 EC EC2010010430A patent/ECSP10010430A/es unknown
- 2010-08-30 EC EC2010010432A patent/ECSP10010432A/es unknown
- 2010-08-30 CO CO10106625A patent/CO6290673A2/es not_active Application Discontinuation
-
2011
- 2011-06-21 US US13/165,281 patent/US20110312975A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CO6290673A2 (es) | 2011-06-20 |
| ECSP10010432A (es) | 2011-01-31 |
| EA201001224A1 (ru) | 2011-08-30 |
| MX2010008518A (es) | 2010-11-10 |
| US20090253737A1 (en) | 2009-10-08 |
| KR20100119773A (ko) | 2010-11-10 |
| US7989469B2 (en) | 2011-08-02 |
| JP2011510985A (ja) | 2011-04-07 |
| AU2009210787A1 (en) | 2009-08-13 |
| CA2713864A1 (en) | 2009-08-13 |
| AR072242A1 (es) | 2010-08-18 |
| EP2244711A4 (en) | 2011-08-24 |
| EP2244711A1 (en) | 2010-11-03 |
| TW200946524A (en) | 2009-11-16 |
| CL2009000246A1 (es) | 2009-06-26 |
| US20110312975A1 (en) | 2011-12-22 |
| WO2009099594A1 (en) | 2009-08-13 |
| BRPI0907502A2 (pt) | 2019-01-15 |
| IL207367A0 (en) | 2010-12-30 |
| ZA201005780B (en) | 2011-04-28 |
| CN101983061A (zh) | 2011-03-02 |
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