ECSP10010471A - Agonistas nicotínicos alfa 7 y antipsicóticos - Google Patents
Agonistas nicotínicos alfa 7 y antipsicóticosInfo
- Publication number
- ECSP10010471A ECSP10010471A EC2010010471A ECSP10010471A ECSP10010471A EC SP10010471 A ECSP10010471 A EC SP10010471A EC 2010010471 A EC2010010471 A EC 2010010471A EC SP10010471 A ECSP10010471 A EC SP10010471A EC SP10010471 A ECSP10010471 A EC SP10010471A
- Authority
- EC
- Ecuador
- Prior art keywords
- antipsychotic
- alfa
- nicotine agonists
- nicotine
- agonists
- Prior art date
Links
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 title 1
- 239000000556 agonist Substances 0.000 title 1
- 230000000561 anti-psychotic effect Effects 0.000 title 1
- 229960002715 nicotine Drugs 0.000 title 1
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 title 1
- 239000000164 antipsychotic agent Substances 0.000 abstract 1
- 239000000181 nicotinic agonist Substances 0.000 abstract 1
- 239000011885 synergistic combination Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
La presente Invención se relaciona con una combinación sinérgica de un agonista nicotínico alfa 7 (?7) y un agente antipsicótico.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2828208P | 2008-02-13 | 2008-02-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP10010471A true ECSP10010471A (es) | 2010-10-30 |
Family
ID=40902222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2010010471A ECSP10010471A (es) | 2008-02-13 | 2010-09-09 | Agonistas nicotínicos alfa 7 y antipsicóticos |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US20110059947A1 (es) |
| EP (2) | EP2254598B1 (es) |
| JP (1) | JP2011511845A (es) |
| KR (1) | KR20100113163A (es) |
| CN (2) | CN101977628A (es) |
| AU (1) | AU2009214625A1 (es) |
| BR (1) | BRPI0907570A2 (es) |
| CA (1) | CA2715268A1 (es) |
| CO (1) | CO6290706A2 (es) |
| CY (1) | CY1114492T1 (es) |
| DK (1) | DK2254598T3 (es) |
| EC (1) | ECSP10010471A (es) |
| ES (1) | ES2430622T3 (es) |
| HR (1) | HRP20130749T1 (es) |
| IL (1) | IL207389A0 (es) |
| MX (1) | MX2010008875A (es) |
| NZ (1) | NZ587312A (es) |
| PL (1) | PL2254598T3 (es) |
| PT (1) | PT2254598E (es) |
| RS (1) | RS52941B (es) |
| RU (1) | RU2481123C2 (es) |
| SG (1) | SG188144A1 (es) |
| SI (1) | SI2254598T1 (es) |
| WO (1) | WO2009102962A2 (es) |
| ZA (1) | ZA201005999B (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8314119B2 (en) * | 2006-11-06 | 2012-11-20 | Abbvie Inc. | Azaadamantane derivatives and methods of use |
| SA08290475B1 (ar) * | 2007-08-02 | 2013-06-22 | Targacept Inc | (2s، 3r)-n-(2-((3-بيردينيل)ميثيل)-1-آزا بيسيكلو[2، 2، 2]أوكت-3-يل)بنزو فيوران-2-كربوكساميد، وصور أملاحه الجديدة وطرق استخدامه |
| KR20130108586A (ko) | 2010-09-23 | 2013-10-04 | 애브비 인코포레이티드 | 아자아다만탄 유도체의 일수화물 |
| CN103442711A (zh) * | 2011-01-18 | 2013-12-11 | 塔加西普特公司 | 精神分裂症中的认知功能障碍的治疗方法 |
| US9139576B2 (en) | 2011-05-03 | 2015-09-22 | Merck Sharp & Dohme Corp. | Aminomethyl biaryl benzotriazole derivatives |
| CA2886010A1 (en) * | 2012-10-02 | 2014-04-10 | Sumitomo Dainippon Pharma Co., Ltd. | Imidazole derivative |
| JP6807094B2 (ja) * | 2016-04-29 | 2021-01-06 | 国立大学法人秋田大学 | クロザピン又はその誘導体の血中薬剤濃度上昇リスク判定方法及び薬剤投与量判定方法 |
| CN115813888A (zh) | 2016-12-20 | 2023-03-21 | 罗曼治疗系统股份公司 | 包含阿塞那平的透皮治疗系统 |
| KR102614709B1 (ko) | 2016-12-20 | 2023-12-18 | 에르테에스 로만 테라피-시스테메 아게 | 아세나핀 및 폴리실록산 또는 폴리이소부틸렌을 함유하는 경피흡수 치료 시스템 |
| CN108727416B (zh) * | 2017-04-20 | 2021-03-09 | 北京大学 | 三环杂芳香体系酰胺衍生物及其制备和用途 |
| JP2020525545A (ja) | 2017-06-26 | 2020-08-27 | エルテーエス ローマン テラピー−ジステーメ アーゲー | アセナピンおよびシリコーンアクリルハイブリッドポリマーを含有する経皮治療システム |
| CN107469087A (zh) * | 2017-09-10 | 2017-12-15 | 孙永丽 | 用于治疗精神病的制剂 |
| PL3810100T3 (pl) | 2018-06-20 | 2025-05-12 | Lts Lohmann Therapie-Systeme Ag | Transdermalny system terapeutyczny zawierający asenapinę |
| US12329862B2 (en) | 2018-06-20 | 2025-06-17 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine |
| JP2024502474A (ja) | 2021-01-08 | 2024-01-19 | アイエフエム デュー インコーポレイテッド | Sting活性に関連する状態を治療するための、尿素を有するヘテロ二環式化合物または類似体およびその組成物 |
| US20240308978A1 (en) * | 2021-01-08 | 2024-09-19 | Ifm Due, Inc. | Compounds and compositions for treating conditions associated with sting activity |
| DE102022114269A1 (de) | 2022-06-07 | 2023-12-07 | Rational Aktiengesellschaft | Gargerät mit einem Selbstreinigungssystem sowie ein Verfahren zum Ändern von Reinigungsparametern für das Gargerät |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5597919A (en) | 1995-01-06 | 1997-01-28 | Dull; Gary M. | Pyrimidinyl or Pyridinyl alkenyl amine compounds |
| US5712270A (en) | 1995-11-06 | 1998-01-27 | American Home Products Corporation | 2-arylamidothiazole derivatives with CNS activity |
| US5616716A (en) | 1996-01-06 | 1997-04-01 | Dull; Gary M. | (3-(5-ethoxypyridin)yl)-alkenyl 1 amine compounds |
| SE9600683D0 (sv) | 1996-02-23 | 1996-02-23 | Astra Ab | Azabicyclic esters of carbamic acids useful in therapy |
| US5663356A (en) | 1996-04-23 | 1997-09-02 | Ruecroft; Graham | Method for preparation of aryl substituted alefinic secondary amino compounds |
| AR013184A1 (es) | 1997-07-18 | 2000-12-13 | Astrazeneca Ab | Aminas heterociclicas espiroazobiciclicas, composicion farmaceutica, uso de dichas aminas para preparar medicamentos y metodo de tratamiento o profilaxis |
| EP1083889B1 (en) | 1998-06-01 | 2003-12-10 | Ortho-McNeil Pharmaceutical, Inc. | Tetrahydronaphtalene compounds and their use for the treatment of neurodegenerative diseases |
| US6953855B2 (en) * | 1998-12-11 | 2005-10-11 | Targacept, Inc. | 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof |
| SE9904176D0 (sv) | 1999-11-18 | 1999-11-18 | Astra Ab | New use |
| IL149669A0 (en) * | 1999-12-10 | 2002-11-10 | Wyeth Corp | NEW THERAPEUTIC COMBINATIONS OF (S) -2-(BENZYLAMINO-METHYL)-2,3,8,9-TETRAHYDRO-7H-1,4-DIOXINO[2,3-e] INDOL-8-ONE AND NEUROLEPTICS FOR THE TREATMENT OR PREVENTION OF PSYCHOTIC DISORDERS |
| US6916828B2 (en) | 2000-06-27 | 2005-07-12 | Laboratorios S.A.L.V.A.T., S.A. | Carbamates derivatived from arylakylamines |
| JP2004506735A (ja) | 2000-08-18 | 2004-03-04 | ファルマシア・アンド・アップジョン・カンパニー | 疾患治療用キヌクリジン置換アリール化合物 |
| WO2002016357A2 (en) | 2000-08-18 | 2002-02-28 | Pharmacia & Upjohn Company | Quinuclidine-substituted aryl moieties for treatment of disease (nicotinic acetylcholine receptor ligands) |
| WO2002016356A2 (en) | 2000-08-18 | 2002-02-28 | Pharmacia & Upjohn Company | Quinuclidine-substituted aryl moieties for treatment of disease (nicotinic acetylcholine receptor ligands) |
| WO2002015662A2 (en) | 2000-08-21 | 2002-02-28 | Pharmacia & Upjohn Company | Quinuclidine-substituted heteroaryl moieties for treatment of disease (nicotinic acetylcholine receptor antagonists |
| AU2001282910A1 (en) | 2000-08-21 | 2002-03-04 | Pharmacia And Upjohn Company | Quinuclidine-substituted heteroaryl moieties for treatment of disease (nicotinic) acetylcholine receptor ligands |
| WO2002017358A2 (en) | 2000-08-21 | 2002-02-28 | Pharmacia & Upjohn Company | Quinuclidine-substituted heteroaryl moieties for treatment of disease (nicotinic acetylcholine receptor antagonists) |
| US6554086B1 (en) * | 2000-10-27 | 2003-04-29 | Invacare Corporation | Obstacle traversing wheelchair |
| RU2296762C2 (ru) | 2000-12-22 | 2007-04-10 | Альмиралль Продесфарма Аг | Карбаматы хинуклидина, способы их получения и фармацевтическая композиция на их основе |
| EP1476448A2 (en) * | 2002-02-19 | 2004-11-17 | PHARMACIA & UPJOHN COMPANY | Azabicyclic compounds for the treatment of disease |
| BR0317019A (pt) * | 2002-12-06 | 2005-10-25 | Pharmacia & Upjohn Co Llc | Sais cristalinos fumarato de 1-azabiciclo[2.2.2]oct-substituìdo-furo[2,3-c]piridinil- carboxamida e suas composições e preparações |
| TW200502222A (en) * | 2003-04-02 | 2005-01-16 | Novartis Ag | Use of 10-hydroxy-10,11-dihydrocarbamazepine derivatives for the treatment of affective disorders |
| WO2004099202A1 (en) * | 2003-05-05 | 2004-11-18 | Pharmacia & Upjohn Company Llc | Quinuclidines substituted bentodioxine carboxamides for the treatment of neurodegenerative diseases |
| US7309699B2 (en) * | 2003-12-22 | 2007-12-18 | Abbott Laboratories | 3-Quinuclidinyl amino-substituted biaryl derivatives |
| MXPA06007213A (es) * | 2003-12-23 | 2006-08-18 | Pfizer Prod Inc | Combinacion terapeutica para la mejora de la cognicion y trastornos sicoticos. |
| CA2601509A1 (en) * | 2005-03-18 | 2006-09-28 | Abbott Laboratories | Alpha7 neuronal nicotinic receptor ligand and antipsychotic compositions |
-
2009
- 2009-02-13 MX MX2010008875A patent/MX2010008875A/es not_active Application Discontinuation
- 2009-02-13 EP EP09709577.2A patent/EP2254598B1/en active Active
- 2009-02-13 PT PT97095772T patent/PT2254598E/pt unknown
- 2009-02-13 AU AU2009214625A patent/AU2009214625A1/en not_active Abandoned
- 2009-02-13 ES ES09709577T patent/ES2430622T3/es active Active
- 2009-02-13 RU RU2010137787/15A patent/RU2481123C2/ru not_active IP Right Cessation
- 2009-02-13 HR HRP20130749AT patent/HRP20130749T1/hr unknown
- 2009-02-13 DK DK09709577.2T patent/DK2254598T3/da active
- 2009-02-13 WO PCT/US2009/034062 patent/WO2009102962A2/en not_active Ceased
- 2009-02-13 CA CA2715268A patent/CA2715268A1/en not_active Abandoned
- 2009-02-13 SI SI200930714T patent/SI2254598T1/sl unknown
- 2009-02-13 KR KR1020107020088A patent/KR20100113163A/ko not_active Ceased
- 2009-02-13 BR BRPI0907570A patent/BRPI0907570A2/pt not_active IP Right Cessation
- 2009-02-13 EP EP13167089.5A patent/EP2633868A1/en not_active Withdrawn
- 2009-02-13 US US12/867,073 patent/US20110059947A1/en not_active Abandoned
- 2009-02-13 NZ NZ587312A patent/NZ587312A/en not_active IP Right Cessation
- 2009-02-13 CN CN2009801102033A patent/CN101977628A/zh active Pending
- 2009-02-13 CN CN2013100500436A patent/CN103143023A/zh active Pending
- 2009-02-13 RS RS20130387A patent/RS52941B/sr unknown
- 2009-02-13 JP JP2010546920A patent/JP2011511845A/ja active Pending
- 2009-02-13 SG SG2013010327A patent/SG188144A1/en unknown
- 2009-02-13 PL PL09709577T patent/PL2254598T3/pl unknown
-
2010
- 2010-08-03 IL IL207389A patent/IL207389A0/en unknown
- 2010-08-23 ZA ZA2010/05999A patent/ZA201005999B/en unknown
- 2010-09-09 EC EC2010010471A patent/ECSP10010471A/es unknown
- 2010-09-10 CO CO10112124A patent/CO6290706A2/es not_active Application Discontinuation
-
2013
- 2013-10-10 CY CY20131100896T patent/CY1114492T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ587312A (en) | 2011-12-22 |
| ES2430622T3 (es) | 2013-11-21 |
| EP2633868A1 (en) | 2013-09-04 |
| HK1147954A1 (en) | 2011-08-26 |
| RS52941B (sr) | 2014-02-28 |
| RU2481123C2 (ru) | 2013-05-10 |
| WO2009102962A2 (en) | 2009-08-20 |
| WO2009102962A3 (en) | 2009-10-08 |
| CY1114492T1 (el) | 2016-10-05 |
| IL207389A0 (en) | 2010-12-30 |
| MX2010008875A (es) | 2010-08-31 |
| PL2254598T3 (pl) | 2013-12-31 |
| EP2254598A2 (en) | 2010-12-01 |
| ZA201005999B (en) | 2011-05-25 |
| RU2010137787A (ru) | 2012-03-20 |
| JP2011511845A (ja) | 2011-04-14 |
| EP2254598B1 (en) | 2013-07-10 |
| PT2254598E (pt) | 2013-10-16 |
| HRP20130749T1 (en) | 2013-10-11 |
| CN103143023A (zh) | 2013-06-12 |
| KR20100113163A (ko) | 2010-10-20 |
| AU2009214625A1 (en) | 2009-08-20 |
| CN101977628A (zh) | 2011-02-16 |
| SI2254598T1 (sl) | 2013-10-30 |
| BRPI0907570A2 (pt) | 2019-09-24 |
| SG188144A1 (en) | 2013-03-28 |
| US20110059947A1 (en) | 2011-03-10 |
| CO6290706A2 (es) | 2011-06-20 |
| CA2715268A1 (en) | 2009-08-20 |
| DK2254598T3 (da) | 2013-07-29 |
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