ECSP10010698A - Derivados de dibenzotiazepina y sus usos - Google Patents

Derivados de dibenzotiazepina y sus usos

Info

Publication number
ECSP10010698A
ECSP10010698A EC2010010698A ECSP10010698A ECSP10010698A EC SP10010698 A ECSP10010698 A EC SP10010698A EC 2010010698 A EC2010010698 A EC 2010010698A EC SP10010698 A ECSP10010698 A EC SP10010698A EC SP10010698 A ECSP10010698 A EC SP10010698A
Authority
EC
Ecuador
Prior art keywords
disorder
dibenzotiazepina
derivatives
compounds
schizophrenia
Prior art date
Application number
EC2010010698A
Other languages
English (en)
Inventor
Michael R Wood
Dean G Brown
Phil Edwards
Steven Wesolowski
James Hulsizer
James R Damewood
James Campbell Muir
Jr M Edward Pierson
Ashokkumar Bhikkappa Shenvi
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41431860&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP10010698(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of ECSP10010698A publication Critical patent/ECSP10010698A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D281/16—[b, f]-condensed

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

Los compuestos de la siguiente fórmula; donde Z se describe en la descripción, sales farmacéuticamente aceptables de estos, composiciones que los comprenden y métodos para tratar el trastorno bipolar, un trastorno de ansiedad, un trastorno del estado de ánimo o la esquizofrenia, u otro trastorno psicótico con dichos compuestos.
EC2010010698A 2008-06-20 2010-12-20 Derivados de dibenzotiazepina y sus usos ECSP10010698A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7441708P 2008-06-20 2008-06-20

Publications (1)

Publication Number Publication Date
ECSP10010698A true ECSP10010698A (es) 2011-01-31

Family

ID=41431860

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2010010698A ECSP10010698A (es) 2008-06-20 2010-12-20 Derivados de dibenzotiazepina y sus usos

Country Status (37)

Country Link
US (3) US20110160184A1 (es)
EP (1) EP2307389B1 (es)
JP (2) JP5468068B2 (es)
KR (1) KR20110019781A (es)
CN (1) CN102131791B (es)
AR (1) AR072200A1 (es)
AU (1) AU2009260905B2 (es)
BR (1) BRPI0914231A2 (es)
CA (1) CA2728675A1 (es)
CL (1) CL2010001471A1 (es)
CR (1) CR11860A (es)
CU (1) CU23884B1 (es)
CY (1) CY1113845T1 (es)
DK (1) DK2307389T3 (es)
DO (1) DOP2010000393A (es)
EA (1) EA201001889A1 (es)
EC (1) ECSP10010698A (es)
ES (1) ES2402084T3 (es)
HN (1) HN2010002683A (es)
HR (1) HRP20130234T1 (es)
IL (2) IL210081A (es)
ME (1) ME01516B (es)
MX (1) MX2010014203A (es)
MY (1) MY157518A (es)
NI (1) NI201000224A (es)
NZ (1) NZ590616A (es)
PE (1) PE20110029A1 (es)
PL (1) PL2307389T3 (es)
PT (1) PT2307389E (es)
RS (1) RS52703B (es)
SI (1) SI2307389T1 (es)
SV (1) SV2010003769A (es)
TW (1) TWI488854B (es)
UA (1) UA105903C2 (es)
UY (1) UY31919A (es)
WO (1) WO2009154563A1 (es)
ZA (1) ZA201100488B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2728675A1 (en) * 2008-06-20 2009-12-23 Astrazeneca Ab Dibenzothiazepine derivatives and use thereof
US20160205082A1 (en) * 2013-08-12 2016-07-14 Graphite Software Corporation Secure authentication and switching to encrypted domains
CN103524455A (zh) * 2013-10-30 2014-01-22 苏州敬业医药化工有限公司 一种制备2-氯-二苯并[b,f][1,4]硫氮杂卓-11-[10H]酮的方法
WO2015074150A1 (en) 2013-11-21 2015-05-28 Graphite Software Corporation Managed domains for remote content and configuration control on mobile information devices
CN104447615A (zh) * 2014-02-28 2015-03-25 广东东阳光药业有限公司 喹硫平中间体的制备方法
JP2026509430A (ja) * 2023-03-08 2026-03-19 ヨハン ヴォルフガング ゲーテ－ウニベルジテート フランクフルト アム マイン Ｓｌａｃｋ活性化化合物及びその医学的用途
EP4428132A1 (en) * 2023-03-08 2024-09-11 Johann-Wolfgang-Goethe-Universität Frankfurt am Main Slack-activating compounds and their medical use

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Also Published As

Publication number Publication date
ME01516B (me) 2014-04-20
CR11860A (es) 2011-02-25
AU2009260905A1 (en) 2009-12-23
ZA201100488B (en) 2011-10-26
JP2014098006A (ja) 2014-05-29
SI2307389T1 (sl) 2013-04-30
CU23884B1 (es) 2013-04-19
EP2307389B1 (en) 2013-01-23
IL210081A (en) 2013-12-31
EP2307389A4 (en) 2012-04-11
NZ590616A (en) 2012-09-28
PT2307389E (pt) 2013-03-28
DOP2010000393A (es) 2011-01-31
HRP20130234T1 (hr) 2013-04-30
SV2010003769A (es) 2011-05-20
DK2307389T3 (da) 2013-04-02
CN102131791B (zh) 2014-12-24
TW201002702A (en) 2010-01-16
CN102131791A (zh) 2011-07-20
EA201001889A1 (ru) 2011-08-30
MX2010014203A (es) 2011-02-22
JP2011524898A (ja) 2011-09-08
HK1156308A1 (en) 2012-06-08
KR20110019781A (ko) 2011-02-28
WO2009154563A1 (en) 2009-12-23
IL229560A (en) 2015-07-30
ES2402084T3 (es) 2013-04-26
RS52703B (sr) 2013-08-30
US8158618B2 (en) 2012-04-17
HN2010002683A (es) 2013-01-15
BRPI0914231A2 (pt) 2015-11-03
PL2307389T3 (pl) 2013-05-31
PE20110029A1 (es) 2011-02-11
CU20100252A7 (es) 2011-11-15
CY1113845T1 (el) 2016-07-27
CL2010001471A1 (es) 2011-05-06
TWI488854B (zh) 2015-06-21
US20090318415A1 (en) 2009-12-24
IL229560A0 (en) 2014-01-30
JP5468068B2 (ja) 2014-04-09
CA2728675A1 (en) 2009-12-23
AR072200A1 (es) 2010-08-11
UA105903C2 (uk) 2014-07-10
US20120202991A1 (en) 2012-08-09
US20110160184A1 (en) 2011-06-30
EP2307389A1 (en) 2011-04-13
MY157518A (en) 2016-06-15
NI201000224A (es) 2012-03-19
US8653257B2 (en) 2014-02-18
IL210081A0 (en) 2011-02-28
AU2009260905B2 (en) 2012-08-23
UY31919A (es) 2010-01-29

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