ECSP109978A - Nuevos compuestos - Google Patents
Nuevos compuestosInfo
- Publication number
- ECSP109978A ECSP109978A EC2010009978A ECSP109978A ECSP109978A EC SP109978 A ECSP109978 A EC SP109978A EC 2010009978 A EC2010009978 A EC 2010009978A EC SP109978 A ECSP109978 A EC SP109978A EC SP109978 A ECSP109978 A EC SP109978A
- Authority
- EC
- Ecuador
- Prior art keywords
- new compounds
- preparation
- compounds
- salts
- diastereomers
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000002483 medication Methods 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Psychology (AREA)
- Endocrinology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Otolaryngology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Objeto de la presente invención son compuestos de la fórmula general (I) , (I)en la que A, B, D, Y, R1, R2, R3, R4 y R5 se definen como se mencionaron en la descripción, sus enantiómeros, sus diastereómeros, sus mezclas y sus sales, en especial sus sales fisiológicamente tolerables con ácidos o bases orgánicos o inorgánicos, que presentan valiosas propiedades, su preparación, los medicamentos que contienen los compuestos farmacológicamente eficaces, su preparación y su uso.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2007/058408 WO2008022945A1 (de) | 2006-08-19 | 2007-08-14 | Arylsulfonamide mit analgetischer wirkung |
| PCT/EP2008/052157 WO2009021758A1 (de) | 2007-08-14 | 2008-02-21 | Arylsulfonamide mit analgetischer wirkung |
| EP08102043A EP2025673A1 (de) | 2007-08-14 | 2008-02-26 | Arylsulfonamide mit analgetischer Wirkung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP109978A true ECSP109978A (es) | 2010-03-31 |
Family
ID=40589564
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2010009978A ECSP109978A (es) | 2007-08-14 | 2010-02-19 | Nuevos compuestos |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US8394805B2 (es) |
| EP (1) | EP2188269B1 (es) |
| JP (1) | JP5250627B2 (es) |
| KR (1) | KR20100055469A (es) |
| CN (1) | CN101821245B (es) |
| AR (1) | AR068341A1 (es) |
| AU (2) | AU2008288431A1 (es) |
| BR (1) | BRPI0815181A2 (es) |
| CA (1) | CA2696261A1 (es) |
| CO (1) | CO6331335A2 (es) |
| EA (1) | EA201000296A1 (es) |
| EC (1) | ECSP109978A (es) |
| MA (1) | MA31613B1 (es) |
| MX (1) | MX2010001664A (es) |
| NZ (1) | NZ583815A (es) |
| PE (1) | PE20090593A1 (es) |
| TN (1) | TN2010000072A1 (es) |
| TW (1) | TW200911744A (es) |
| UY (1) | UY31287A1 (es) |
| WO (1) | WO2009021944A1 (es) |
| ZA (1) | ZA201008350B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102006039003A1 (de) * | 2006-08-19 | 2008-02-21 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Verbindungen |
| EP2025675A1 (de) | 2007-08-14 | 2009-02-18 | Boehringer Ingelheim International GmbH | Arylsulfonamide mit analgetischer Wirkung |
| EP2188269B1 (de) | 2007-08-14 | 2014-05-07 | Boehringer Ingelheim International GmbH | Arylsulfonamide mit analgetischer wirkung |
| CA2712582A1 (en) * | 2008-02-06 | 2009-08-13 | Norbert Hauel | Aryl sulfonamides as effective analgesics |
| KR20110053424A (ko) * | 2008-08-12 | 2011-05-23 | 베링거 인겔하임 인터내셔날 게엠베하 | 사이클로알킬-치환된 피페라진 화합물의 제조 방법 |
| US8207335B2 (en) * | 2009-02-13 | 2012-06-26 | Boehringer Ingelheim International Gmbh | Process for making certain compounds having B1 antagonistic activity |
| CN103003253A (zh) * | 2010-08-05 | 2013-03-27 | 贝林格尔.英格海姆国际有限公司 | 2-{2-[[(4-甲氧基-2,6-二甲基苯基)磺酰基]-(甲基)氨基]乙氧基}-n-甲基-n-[3-(4-甲基哌嗪-1-基)环己基]乙酰胺的酸加成盐及其作为缓激肽b1受体拮抗剂的用途 |
| WO2012022796A2 (de) | 2010-08-20 | 2012-02-23 | Boehringer Ingelheim International Gmbh | Neue kombinationen |
| WO2012028331A1 (en) | 2010-09-03 | 2012-03-08 | Grünenthal GmbH | Substituted tetrahydropyrrolopyrazine derivatives |
| US12570660B2 (en) * | 2019-08-16 | 2026-03-10 | Cyclacel Pharmaceuticals, Inc | Process for the preparation of a pyrimidino-diazepine derivative |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0173552B1 (en) | 1984-08-24 | 1991-10-09 | The Upjohn Company | Recombinant dna compounds and the expression of polypeptides such as tpa |
| IL115420A0 (en) | 1994-09-26 | 1995-12-31 | Zeneca Ltd | Aminoheterocyclic derivatives |
| SI1249233T1 (sl) | 1999-11-26 | 2009-02-28 | Shionogi & Co | Antagonisti NPYY5 |
| FR2819254B1 (fr) | 2001-01-08 | 2003-04-18 | Fournier Lab Sa | Nouveaux composes de la n-(phenylsulfonyl) glycine, leur procede de preparation et leur utilisation pour obtenir des compostions pharmaceutiques |
| FR2840897B1 (fr) * | 2002-06-14 | 2004-09-10 | Fournier Lab Sa | Nouveaux derives d'arylsulfonamides et leur utilisation en therapeutique |
| EP1572678A4 (en) | 2002-12-19 | 2008-05-07 | Elan Pharm Inc | SUBSTITUTED N-PHENYL SULPHONAMIDES ALSBRADYKININ ANTAGONISTS |
| CN1756551A (zh) * | 2003-01-31 | 2006-04-05 | 普雷迪克医药品控股公司 | 新型芳基哌嗪基化合物 |
| BRPI0408689B8 (pt) | 2003-03-25 | 2021-05-25 | Laboratoires Fournier S A | derivados de benzenosulfonamida, método para preparação e utilização disso para o tratamento da dor |
| US7521457B2 (en) | 2004-08-20 | 2009-04-21 | Boehringer Ingelheim International Gmbh | Pyrimidines as PLK inhibitors |
| AU2005289881A1 (en) | 2004-09-23 | 2006-04-06 | Amgen Inc. | Substituted sulfonamidopropionamides and methods of use |
| WO2006035967A1 (en) | 2004-09-30 | 2006-04-06 | Taisho Pharmaceutical Co., Ltd. | Pyridine derivatives and their use as medicaments for treating diseases related to mch receptor |
| DE102005013967A1 (de) | 2004-11-05 | 2006-10-05 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Bradykinin-B1-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel |
| WO2006071775A2 (en) | 2004-12-29 | 2006-07-06 | Elan Pharmaceuticals, Inc. | Novel compounds useful for bradykinin b1 receptor antagonism |
| JP5603770B2 (ja) | 2007-05-31 | 2014-10-08 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ccr2受容体拮抗薬およびその使用 |
| DE102007034620A1 (de) | 2007-07-25 | 2009-01-29 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue B1-Antagonisten |
| EP2188269B1 (de) | 2007-08-14 | 2014-05-07 | Boehringer Ingelheim International GmbH | Arylsulfonamide mit analgetischer wirkung |
| JP2011505334A (ja) | 2007-08-14 | 2011-02-24 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規化合物 |
| DE102007046887A1 (de) | 2007-09-28 | 2009-04-09 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung von (1R,5S)-Anhydroecgoninestersalzen |
-
2008
- 2008-08-12 EP EP08803005.1A patent/EP2188269B1/de active Active
- 2008-08-12 PE PE2008001366A patent/PE20090593A1/es not_active Application Discontinuation
- 2008-08-12 CN CN2008801116296A patent/CN101821245B/zh not_active Expired - Fee Related
- 2008-08-12 CA CA2696261A patent/CA2696261A1/en not_active Abandoned
- 2008-08-12 US US12/672,460 patent/US8394805B2/en active Active
- 2008-08-12 MX MX2010001664A patent/MX2010001664A/es active IP Right Grant
- 2008-08-12 JP JP2010520555A patent/JP5250627B2/ja active Active
- 2008-08-12 EA EA201000296A patent/EA201000296A1/ru unknown
- 2008-08-12 BR BRPI0815181 patent/BRPI0815181A2/pt not_active Application Discontinuation
- 2008-08-12 KR KR1020107005536A patent/KR20100055469A/ko not_active Ceased
- 2008-08-12 WO PCT/EP2008/060562 patent/WO2009021944A1/de not_active Ceased
- 2008-08-12 AU AU2008288431A patent/AU2008288431A1/en not_active Abandoned
- 2008-08-12 NZ NZ583815A patent/NZ583815A/en not_active IP Right Cessation
- 2008-08-13 UY UY31287A patent/UY31287A1/es not_active Application Discontinuation
- 2008-08-13 TW TW097130828A patent/TW200911744A/zh unknown
- 2008-08-13 AR ARP080103538A patent/AR068341A1/es unknown
-
2009
- 2009-02-13 AU AU2009281472A patent/AU2009281472A1/en not_active Abandoned
-
2010
- 2010-02-12 CO CO10016009A patent/CO6331335A2/es active IP Right Grant
- 2010-02-12 TN TNP2010000072A patent/TN2010000072A1/fr unknown
- 2010-02-15 MA MA32623A patent/MA31613B1/fr unknown
- 2010-02-19 EC EC2010009978A patent/ECSP109978A/es unknown
- 2010-11-22 ZA ZA2010/08350A patent/ZA201008350B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA201008350B (en) | 2011-08-31 |
| US8394805B2 (en) | 2013-03-12 |
| CN101821245A (zh) | 2010-09-01 |
| MA31613B1 (fr) | 2010-08-02 |
| CN101821245B (zh) | 2012-10-10 |
| EP2188269B1 (de) | 2014-05-07 |
| MX2010001664A (es) | 2010-03-10 |
| TN2010000072A1 (en) | 2011-09-26 |
| JP5250627B2 (ja) | 2013-07-31 |
| CA2696261A1 (en) | 2009-02-19 |
| AR068341A1 (es) | 2009-11-11 |
| BRPI0815181A2 (pt) | 2015-03-31 |
| JP2010535839A (ja) | 2010-11-25 |
| PE20090593A1 (es) | 2009-06-03 |
| KR20100055469A (ko) | 2010-05-26 |
| NZ583815A (en) | 2012-03-30 |
| AU2008288431A1 (en) | 2009-02-19 |
| AU2009281472A1 (en) | 2010-02-18 |
| EP2188269A1 (de) | 2010-05-26 |
| EA201000296A1 (ru) | 2010-08-30 |
| TW200911744A (en) | 2009-03-16 |
| CO6331335A2 (es) | 2011-10-20 |
| US20110098282A1 (en) | 2011-04-28 |
| UY31287A1 (es) | 2009-04-30 |
| WO2009021944A1 (de) | 2009-02-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ECSP109978A (es) | Nuevos compuestos | |
| ECSP12012161A (es) | Compuestos en calidad de antagonistas de Bradiquinina-b1 | |
| UY30979A1 (es) | Pirrolidinamidas sustituidas, su preparacion y su uso como medicamentos | |
| ECSP088824A (es) | Prolinamidas sustituidas, su preparación y su uso como medicamentos | |
| ECSP078058A (es) | Nuevas glicinamidas sustituidas, su preparación y su uso como medicamentos | |
| ECSP10010105A (es) | Antagonistas de cgrp | |
| UY29437A1 (es) | Nuevos antagonistas de cgrp | |
| ECSP10010722A (es) | Compuestos orgánicos | |
| UY29071A1 (es) | Aminas policíclicas sustituidas con arilo, procedimientos para su preparación y su uso como medicamentos. | |
| UY31524A1 (es) | Nuevos compuestos 010 | |
| UY30498A1 (es) | Nueva clase de compuestos de benzimidazolilo, sus sales, composiciones farmacéuticas conteniéndolos y aplicaciones | |
| CR11750A (es) | Pirimidin-5-carboxamidas sustituidas 281 | |
| CR11370A (es) | Inhibidores de quinasas simil polo | |
| UY28859A1 (es) | Antagonistas de cgrp seleccionados, procedimiento para su preparación así como su uso como medicamento | |
| ECSP088638A (es) | Bencensulfonil-cromano, tiocromano, tetrahidronaftaleno e inhibidores de gamma secretasa relacionados | |
| UY28773A1 (es) | Nuevas amidas de ácidos carboxílicos, su preparación y su uso como medicamentos. | |
| MX2009003383A (es) | Nuevos derivados de diosmetina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. | |
| UY28848A1 (es) | Antagonistas de cgrp seleccionados, procedimientos para su preparación, y su empleo como medicamentos | |
| ECSP088194A (es) | Antagonistas de cgrp seleccionados, procedimientos para su preparación, así como su uso como medicamentos | |
| CR11273A (es) | Derivados-2-ona disustituidos en 3, su preparacion y su aplicacion en terapeutica | |
| UY33565A (es) | Compuestos de tetrahidrofuranilo disustituidos como antagonistas de bradiquinina-B1 | |
| UY31286A1 (es) | Antagonistas de receptores de bradiquinina b1. proceso de preparación y aplicaciones. | |
| HN2011000404A (es) | Derivados de enfumafungina y composicion comprendiendo los mismos | |
| DOP2007000121A (es) | Imidazolidina-2,4-dionas sustituidas con arilaminoarilalquilo, procedimiento para su preparación, medicamentos que comprenden estos compuestos y su uso | |
| UY31642A1 (es) | Imidazolidina-2,4.dionas sustituidas con arilo, procesos para su preparación, medicamentos que comprenden estos compuestos y uso de los mismos. |