ECSP11010912A - Compuestos de pirrol - Google Patents

Compuestos de pirrol

Info

Publication number
ECSP11010912A
ECSP11010912A EC2011010912A ECSP11010912A ECSP11010912A EC SP11010912 A ECSP11010912 A EC SP11010912A EC 2011010912 A EC2011010912 A EC 2011010912A EC SP11010912 A ECSP11010912 A EC SP11010912A EC SP11010912 A ECSP11010912 A EC SP11010912A
Authority
EC
Ecuador
Prior art keywords
halogen
optionally substituted
group optionally
alkyl group
hydrogen atom
Prior art date
Application number
EC2011010912A
Other languages
English (en)
Inventor
Haruyuki Nishida
Yasuyoshi Arikawa
Ikuo Fujimori
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41508823&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP11010912(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of ECSP11010912A publication Critical patent/ECSP11010912A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La presente invención se refiere a un compuesto representado por la fórmula:en donde A es grupo piridilo que tiene al menos un sustituyenteen donde R1, R2 y R3 son cada uno un átomo de hidrógeno, un átomo de halógeno, un grupo alquilo C1-6 opcionalmente sustituido con halógeno o un grupo alcoxi C1-6 opcionalmente sustituido con halógeno, R4 y R6 son cada uno un átomo de hidrógeno, un átomo de halógeno o un grupo alquilo C1-6 opcionalmente sustituido con halógeno, R5 es un átomo de hidrógeno, un átomo de halógeno, un grupo alquilo C1-6 opcionalmente sustituido con halógeno o un grupo alcoxi C1-6 opcionalmente sustituido con halógeno y R7 es un átomo de hidrógeno o un grupo alquilo C1-6 opcionalmente sustituido con halógeno o una de sus sales o una composición farmacéutica que los contiene.
EC2011010912A 2008-08-27 2011-03-25 Compuestos de pirrol ECSP11010912A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2008218851 2008-08-27
JP2008269099 2008-10-17

Publications (1)

Publication Number Publication Date
ECSP11010912A true ECSP11010912A (es) 2011-04-29

Family

ID=41508823

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2011010912A ECSP11010912A (es) 2008-08-27 2011-03-25 Compuestos de pirrol

Country Status (38)

Country Link
US (3) US8592597B2 (es)
EP (1) EP2318390B1 (es)
JP (1) JP5638515B2 (es)
KR (1) KR101629181B1 (es)
CN (1) CN102197033B (es)
AR (1) AR073136A1 (es)
AU (1) AU2009284867B2 (es)
BR (1) BRPI0917705A2 (es)
CA (1) CA2735162C (es)
CL (1) CL2011000402A1 (es)
CO (1) CO6321166A2 (es)
CR (1) CR20110169A (es)
CY (1) CY1114452T1 (es)
DK (1) DK2318390T3 (es)
DO (1) DOP2011000061A (es)
EA (1) EA019741B1 (es)
EC (1) ECSP11010912A (es)
ES (1) ES2423289T3 (es)
GE (1) GEP20135786B (es)
HR (1) HRP20130653T1 (es)
IL (1) IL211335A (es)
JO (1) JO2871B1 (es)
MA (1) MA32647B1 (es)
ME (1) ME01598B (es)
MX (1) MX2011001955A (es)
MY (1) MY152008A (es)
NZ (1) NZ591793A (es)
PE (2) PE20110300A1 (es)
PL (1) PL2318390T3 (es)
PT (1) PT2318390E (es)
RS (1) RS52872B (es)
SI (1) SI2318390T1 (es)
SM (1) SMT201300085B (es)
TW (1) TWI473798B (es)
UA (1) UA105185C2 (es)
UY (1) UY32074A (es)
WO (1) WO2010024451A1 (es)
ZA (1) ZA201101774B (es)

Cited By (2)

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US10835541B2 (en) 2015-07-30 2020-11-17 Takeda Pharmaceutical Company Limited Tablet
US11696893B2 (en) 2017-07-10 2023-07-11 Takeda Pharmaceutical Company Limited Preparation comprising vonoprazan

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BRPI0917705A2 (pt) * 2008-08-27 2016-02-16 Takeda Pharmaceutical composto, pró-droga, composição farmacêutica, método para tratar ou prevenir uma doença ou condição, e, uso do composto
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CN102452979B (zh) * 2010-11-03 2015-04-01 天津药明康德新药开发有限公司 5-氟-3-吡啶磺酰氯的合成方法
CN102863371B (zh) * 2011-07-06 2016-04-13 中国科学院上海有机化学研究所 氟代二氢吡咯或氟代吡咯
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AR091567A1 (es) 2012-06-27 2015-02-11 Takeda Pharmaceutical Preparacion liquida, metodo, kit de inyeccion
US9487485B2 (en) 2013-02-28 2016-11-08 Takeda Pharmaceutical Company Limited Method for producing sulfonyl chloride compound
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KR102084185B1 (ko) * 2013-08-29 2020-03-04 주식회사 대웅제약 테트라히드로사이클로펜타피롤 유도체 및 이의 제조방법
CN105367550A (zh) * 2014-08-11 2016-03-02 江苏柯菲平医药股份有限公司 四氢环戊二烯并[c]吡咯类衍生物、其制备方法及其在医药上的应用
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WO2016138099A1 (en) 2015-02-24 2016-09-01 Massachusetts Institute Of Technology Use of ghrelin or functional ghrelin receptor agonists to prevent and treat stress-sensitive psychiatric illness
EP3331870B1 (de) 2015-08-07 2021-06-16 Bayer CropScience Aktiengesellschaft 2-(het)aryl-substituierte kondensierte heterocyclen-derivate als schädlingsbekämpfungsmittel
CN106430006B (zh) * 2016-08-18 2018-06-12 国网湖南省电力公司带电作业中心 配电线路移动式绝缘登高作业装置及方法
CN108203430A (zh) * 2016-12-16 2018-06-26 天地人和生物科技有限公司 一种新型可逆性质子泵抑制剂及其制备方法和用途
KR102126576B1 (ko) 2018-09-19 2020-06-24 주식회사 대웅제약 4-메톡시 피롤 유도체의 제조 방법
CN113527536B (zh) * 2020-04-21 2024-03-22 杭州德柯医疗科技有限公司 一种含氟多糖高分子化合物及其制备方法
AU2021293694B2 (en) * 2020-06-17 2023-12-21 Ildong Pharmaceutical Co., Ltd. Novel Acid Secretion Inhibitor and use thereof
EP4074317A1 (en) 2021-04-14 2022-10-19 Bayer AG Phosphorus derivatives as novel sos1 inhibitors
CN113620930B (zh) * 2021-07-12 2022-08-16 南京烁慧医药科技有限公司 一种含磺酰胺结构的化合物及其制备方法和应用、一种药物组合物及应用
CN118541361A (zh) * 2021-12-15 2024-08-23 日东制药株式会社 1-磺酰基吡咯衍生物的新型盐、其制备方法和包括其的药物组合物
WO2023113458A1 (en) * 2021-12-15 2023-06-22 Ildong Pharmaceutical Co., Ltd. Novel salt of 1-sulfonyl pyrrole derivative, preparation method thereof and pharmaceutical composition comprising thereof
KR20230102353A (ko) * 2021-12-30 2023-07-07 주식회사 대웅제약 삼중음성유방암의 예방 또는 치료용 약학적 조성물

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10835541B2 (en) 2015-07-30 2020-11-17 Takeda Pharmaceutical Company Limited Tablet
US11696893B2 (en) 2017-07-10 2023-07-11 Takeda Pharmaceutical Company Limited Preparation comprising vonoprazan

Also Published As

Publication number Publication date
CY1114452T1 (el) 2016-10-05
CL2011000402A1 (es) 2011-07-29
ME01598B (me) 2014-09-20
US8993598B2 (en) 2015-03-31
MA32647B1 (fr) 2011-09-01
UY32074A (es) 2010-03-26
US20100056577A1 (en) 2010-03-04
DK2318390T3 (da) 2013-07-08
EP2318390B1 (en) 2013-05-01
SMT201300085B (it) 2013-09-06
DOP2011000061A (es) 2011-04-15
IL211335A (en) 2013-12-31
US8592597B2 (en) 2013-11-26
KR101629181B1 (ko) 2016-06-13
PE20110300A1 (es) 2011-06-16
CN102197033B (zh) 2014-07-16
ZA201101774B (en) 2012-06-27
US20140031393A1 (en) 2014-01-30
PT2318390E (pt) 2013-07-10
UA105185C2 (uk) 2014-04-25
CO6321166A2 (es) 2011-09-20
TW201010993A (en) 2010-03-16
AU2009284867A2 (en) 2011-04-21
BRPI0917705A2 (pt) 2016-02-16
CA2735162A1 (en) 2010-03-04
CN102197033A (zh) 2011-09-21
AU2009284867A1 (en) 2010-03-04
CA2735162C (en) 2015-06-23
ES2423289T3 (es) 2013-09-19
TWI473798B (zh) 2015-02-21
AR073136A1 (es) 2010-10-13
AU2009284867B2 (en) 2014-08-28
WO2010024451A1 (en) 2010-03-04
US20110172275A1 (en) 2011-07-14
PE20141174A1 (es) 2014-09-19
SI2318390T1 (sl) 2013-08-30
RS52872B (sr) 2013-12-31
GEP20135786B (en) 2013-03-11
HRP20130653T1 (en) 2013-08-31
NZ591793A (en) 2012-11-30
JO2871B1 (en) 2015-03-15
EP2318390A1 (en) 2011-05-11
HK1157756A1 (en) 2012-07-06
PL2318390T3 (pl) 2013-09-30
JP2012501296A (ja) 2012-01-19
JP5638515B2 (ja) 2014-12-10
MY152008A (en) 2014-08-15
EA019741B1 (ru) 2014-05-30
US8969387B2 (en) 2015-03-03
IL211335A0 (en) 2011-04-28
CR20110169A (es) 2011-05-16
KR20110071067A (ko) 2011-06-28
MX2011001955A (es) 2011-03-29
EA201170384A1 (ru) 2011-10-31

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