CR20160082A - Nuevo derivado de triazina - Google Patents

Nuevo derivado de triazina

Info

Publication number
CR20160082A
CR20160082A CR20160082A CR20160082A CR20160082A CR 20160082 A CR20160082 A CR 20160082A CR 20160082 A CR20160082 A CR 20160082A CR 20160082 A CR20160082 A CR 20160082A CR 20160082 A CR20160082 A CR 20160082A
Authority
CR
Costa Rica
Prior art keywords
triazina
new derivative
new
derivative
substituted
Prior art date
Application number
CR20160082A
Other languages
English (en)
Inventor
Wataru Kawahata
Tokiko ASAMI
Masaaki Sawa
Yuko ASAMITSU
Takayuki Irie
Takahiro Miyake
Takao Kiyol
Original Assignee
Carna Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carna Biosciences Inc filed Critical Carna Biosciences Inc
Publication of CR20160082A publication Critical patent/CR20160082A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere a proporcionar un nuevo derivado de triazina de la fórmula (I): donde R1 representa un grupo alquilo inferior sustituido o no sustituido
CR20160082A 2013-07-26 2016-02-18 Nuevo derivado de triazina CR20160082A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2013155331 2013-07-26
JP2013187987 2013-09-11
JP2014073227 2014-03-31

Publications (1)

Publication Number Publication Date
CR20160082A true CR20160082A (es) 2016-06-08

Family

ID=52393193

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20160082A CR20160082A (es) 2013-07-26 2016-02-18 Nuevo derivado de triazina

Country Status (15)

Country Link
US (1) US9656995B2 (es)
EP (1) EP3026050B1 (es)
JP (1) JP6156953B2 (es)
KR (1) KR101742550B1 (es)
CN (1) CN105683178B (es)
AU (1) AU2014294225B2 (es)
CA (1) CA2919068C (es)
CR (1) CR20160082A (es)
DK (1) DK3026050T3 (es)
ES (1) ES2699452T3 (es)
IL (1) IL243737B (es)
NO (1) NO20160292A1 (es)
PH (1) PH12016500152A1 (es)
SG (1) SG11201600497VA (es)
WO (1) WO2015012149A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3048102A1 (en) * 2013-09-20 2016-07-27 Carna Biosciences Inc. Novel triazine derivative
ES2968023T3 (es) 2016-11-25 2024-05-06 Carna Biosciences Inc Derivados de oxoisoquinolina novedosos
EP4101468A4 (en) * 2020-02-05 2024-02-28 Carna Biosciences, Inc. Anticancer agent composition
WO2022034914A1 (ja) * 2020-08-13 2022-02-17 カルナバイオサイエンス株式会社 易溶性固形製剤およびその製法
JPWO2022102715A1 (es) * 2020-11-13 2022-05-19
WO2024245578A1 (en) 2023-06-02 2024-12-05 Netherlands Translational Research Center Holding B.V. Therapeutic combinations of an irreversible btk inhibitor and a macrocyclic reversible btk inhibitor
WO2024245577A1 (en) 2023-06-02 2024-12-05 Netherlands Translational Research Center Holding B.V. Therapeutic combinations of an irreversible btk inhibitor and a reversible btk inhibitor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2300459T3 (pl) 2008-07-02 2013-10-31 Hoffmann La Roche Nowe fenylopirazynony jako inhibitory kinazy
US8299077B2 (en) 2009-03-02 2012-10-30 Roche Palo Alto Llc Inhibitors of Bruton's tyrosine kinase
KR20140052032A (ko) 2011-08-17 2014-05-02 에프. 호프만-라 로슈 아게 브루톤 티로신 키나아제의 억제제
MX2014006674A (es) * 2011-12-09 2014-09-04 Hoffmann La Roche Inhibidores de tirosina cinasa de bruton.
CN104169260A (zh) * 2012-03-09 2014-11-26 卡尔那生物科学株式会社 新三嗪衍生物
WO2013161848A1 (ja) 2012-04-27 2013-10-31 カルナバイオサイエンス株式会社 新規1,2,4-トリアジン誘導体

Also Published As

Publication number Publication date
US20160168122A1 (en) 2016-06-16
NO20160292A1 (en) 2016-02-19
PH12016500152A1 (en) 2016-04-25
DK3026050T3 (en) 2019-02-18
EP3026050A4 (en) 2016-12-14
EP3026050B1 (en) 2018-11-07
CA2919068A1 (en) 2015-01-29
SG11201600497VA (en) 2016-02-26
CN105683178A (zh) 2016-06-15
CN105683178B (zh) 2019-04-12
IL243737A0 (en) 2016-04-21
CA2919068C (en) 2018-03-20
AU2014294225B2 (en) 2017-02-23
ES2699452T3 (es) 2019-02-11
JP6156953B2 (ja) 2017-07-05
KR101742550B1 (ko) 2017-06-01
IL243737B (en) 2019-09-26
WO2015012149A1 (ja) 2015-01-29
AU2014294225A1 (en) 2016-03-03
EP3026050A1 (en) 2016-06-01
JPWO2015012149A1 (ja) 2017-03-02
KR20160041946A (ko) 2016-04-18
US9656995B2 (en) 2017-05-23

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)