ECSP12011577A - Produccion recombinante de péptidos - Google Patents

Produccion recombinante de péptidos

Info

Publication number
ECSP12011577A
ECSP12011577A EC2012011577A ECSP12011577A ECSP12011577A EC SP12011577 A ECSP12011577 A EC SP12011577A EC 2012011577 A EC2012011577 A EC 2012011577A EC SP12011577 A ECSP12011577 A EC SP12011577A EC SP12011577 A ECSP12011577 A EC SP12011577A
Authority
EC
Ecuador
Prior art keywords
peptides
recombinant production
precursor proteins
assembled
self
Prior art date
Application number
EC2012011577A
Other languages
English (en)
Inventor
Theodor Fehr
Daniel Hümmerich
Burghard Liebmann
Carsten Schwalb
Heike Brüser
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se filed Critical Basf Se
Publication of ECSP12011577A publication Critical patent/ECSP12011577A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente invención se refiere a proteínas precursoras repetitivas autoensambladas, secuencias de ácidos nucleicos y constructos de expresión que los codifican, y a métodos para la producción recombinante de péptidos mediante el uso de dichas proteínas precursoras.
EC2012011577A 2009-06-03 2012-01-06 Produccion recombinante de péptidos ECSP12011577A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP09161837 2009-06-03

Publications (1)

Publication Number Publication Date
ECSP12011577A true ECSP12011577A (es) 2012-02-29

Family

ID=43298234

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2012011577A ECSP12011577A (es) 2009-06-03 2012-01-06 Produccion recombinante de péptidos

Country Status (20)

Country Link
US (1) US9481719B2 (es)
EP (1) EP2437769B1 (es)
JP (1) JP5730293B2 (es)
KR (2) KR101812842B1 (es)
CN (1) CN102724992B (es)
AR (1) AR076977A1 (es)
AU (1) AU2010255732B8 (es)
BR (1) BRPI1011144B8 (es)
CA (1) CA2763626A1 (es)
CL (1) CL2011003075A1 (es)
CR (1) CR20110619A (es)
EC (1) ECSP12011577A (es)
ES (1) ES2763168T3 (es)
IL (1) IL216619A0 (es)
MX (1) MX2011012906A (es)
NZ (2) NZ596735A (es)
PE (1) PE20121033A1 (es)
RU (1) RU2548815C2 (es)
TW (1) TWI429750B (es)
WO (1) WO2010139736A2 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8039582B2 (en) * 2005-02-24 2011-10-18 The University Of Queensland Peptide networks
WO2012079125A1 (en) * 2010-12-14 2012-06-21 The University Of Queensland Designed biosurfactants, their manufacture, purification and use
CN103740659B (zh) * 2012-05-10 2015-06-03 江南大学 一种提高酶热稳定性的方法
CN103756979B (zh) * 2012-05-10 2015-07-08 江南大学 一种提高酶热稳定性的方法
CN103740661B (zh) * 2012-05-10 2015-06-03 江南大学 一种提高酶热稳定性的方法
EP2864349A4 (en) * 2012-06-20 2016-02-24 Univ California DYNAMIC BIOMIMETIC SYNZYM CATALYST, CATALYSIS AND CATALYST SYSTEMS
WO2014056199A1 (zh) * 2012-10-12 2014-04-17 清华大学 多肽的产生和纯化方法
WO2017055587A1 (de) * 2015-10-01 2017-04-06 Basf Se Rekombinante herstellung von peptiden
KR101976923B1 (ko) * 2017-05-10 2019-05-10 건국대학교 산학협력단 D-루이신 치환을 통해 항균 효과를 증진시킨 항생 펩타이드 및 이의 용도
KR101970875B1 (ko) * 2017-05-10 2019-04-19 건국대학교 산학협력단 글루탐산 치환을 통해 항균 효과를 증진시킨 항생 펩타이드 및 이의 용도
KR101970876B1 (ko) * 2017-05-10 2019-04-19 건국대학교 산학협력단 D-라이신 치환을 통해 항균 효과를 증진시킨 항생 펩타이드 및 이의 용도
CN106496307B (zh) * 2016-11-09 2019-11-01 湖南科技学院 一种新的抗菌肽及其用途
CN108503690B (zh) * 2017-02-28 2020-07-03 暨南大学 一种促进创伤后组织修复与再生的修复肽及其应用
US11260101B2 (en) 2017-02-28 2022-03-01 Jinan University Repair peptide for use in promoting post-traumatic tissue repair and regeneration, and application thereof
WO2020048996A1 (en) 2018-09-06 2020-03-12 ETH Zürich Self-assembling globular proteins and uses thereof
CN111388374B (zh) * 2020-04-11 2022-09-06 百草堂(湖北)制药有限公司 一种洗发露
CN116981680A (zh) 2021-01-14 2023-10-31 生物催化剂有限责任公司 用于肽生产的组合物和方法
CN116874613B (zh) * 2023-09-06 2023-11-17 南京华盖制药有限公司 一种广谱高效的抗菌多肽aph143及其制备方法和应用

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GB9504761D0 (en) 1995-03-09 1995-04-26 Unilever Plc Amphiphilic peptide and analogs thereof
KR100263583B1 (ko) * 1997-05-28 2000-08-01 박종헌 항균 펩타이드의 대량 제조방법 및 그에 유용한 플라즈미드 벡타
AU1255300A (en) * 1998-11-20 2000-06-13 Micrologix Biotech, Inc. Efficient methods for producing antimicrobial cationic peptides in host cells
WO2002099082A2 (en) * 2001-06-06 2002-12-12 University Of Wyoming Expression of spider silk proteins in higher plants
KR100438416B1 (ko) 2001-09-19 2004-07-02 학교법인조선대학교 Ｃａ－ｍａ 펩타이드의 아미노산 중 하나 또는 그 이상을치환하여 ＋ 전극과 소수성 영역이 증가된 신규한펩타이드 및 그를 포함하는 약학적 조성물
EP1448595B1 (en) * 2001-11-20 2006-10-18 Novozymes A/S Antimicrobial polypeptides from pseudoplectania nigrella
US20030219854A1 (en) 2002-03-21 2003-11-27 Micrologix Biotech Inc. Methods for producing modified anti-infective peptides
CA2482995C (en) * 2002-04-22 2013-01-29 Dow Global Technologies Inc. Low-cost production of peptides
WO2004082634A2 (en) 2003-03-17 2004-09-30 The Trustees Of The University Of Pennsylvania Facially amphiphilic polymers and oligomers and uses thereof
CN101018806B (zh) 2004-07-22 2014-05-07 Am丝绸有限责任公司 重组蜘蛛丝蛋白
AU2006286753B2 (en) * 2005-08-29 2011-08-18 Amsilk Gmbh Modified spider silk proteins
US7709227B2 (en) 2006-01-04 2010-05-04 Phasebio Pharmaceuticals, Inc. Multimeric ELP fusion constructs
CN104856962A (zh) 2006-01-20 2015-08-26 慕尼黑工业大学 两性自组装蛋白质在配制低水溶性的有效物质中的用途
CN101784655A (zh) * 2007-04-27 2010-07-21 菲尼克斯股份有限公司 可溶性重组二十面体病毒样颗粒的改良生成和体内装配
CA2690658C (en) 2007-06-20 2016-08-09 Basf Se Synthetic repetitive proteins, their production and use thereof
RU2491052C2 (ru) * 2007-12-21 2013-08-27 Басф Се Противоперхотные композиции, содержащие пептиды

Also Published As

Publication number Publication date
AU2010255732B8 (en) 2014-03-13
US20120088268A1 (en) 2012-04-12
KR101834018B1 (ko) 2018-03-05
CL2011003075A1 (es) 2012-06-29
AU2010255732A8 (en) 2014-03-13
CR20110619A (es) 2012-02-09
TWI429750B (zh) 2014-03-11
NZ596735A (en) 2013-10-25
WO2010139736A3 (de) 2011-03-10
IL216619A0 (en) 2012-02-29
PE20121033A1 (es) 2012-08-02
ES2763168T3 (es) 2020-05-27
TW201103981A (en) 2011-02-01
AU2010255732B2 (en) 2013-09-12
AR076977A1 (es) 2011-07-20
WO2010139736A2 (de) 2010-12-09
NZ615847A (en) 2014-11-28
US9481719B2 (en) 2016-11-01
BRPI1011144B1 (pt) 2021-02-02
KR20140127344A (ko) 2014-11-03
BRPI1011144A2 (pt) 2016-10-25
EP2437769A2 (de) 2012-04-11
EP2437769B1 (de) 2019-09-25
JP2012528579A (ja) 2012-11-15
RU2011153757A (ru) 2013-07-20
CA2763626A1 (en) 2010-12-09
AU2010255732A1 (en) 2011-12-22
CN102724992A (zh) 2012-10-10
JP5730293B2 (ja) 2015-06-10
KR20120014940A (ko) 2012-02-20
BRPI1011144B8 (pt) 2021-05-25
CN102724992B (zh) 2016-05-18
KR101812842B1 (ko) 2017-12-27
MX2011012906A (es) 2012-02-01
RU2548815C2 (ru) 2015-04-20

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