ECSP12011971A - NUEVOS DERIVADOS (HETEROCICLO-TETRAHIDRO-PIRIDIN)-(PIPERAZINIL)-1-ALCANONA Y (HETEROCICLO-DIHIDRO-PIRROLIDIN)-(PIPERAZINIL)-1-ALCANONA Y SU UTILIZACIÓN COMO INHIBIDORES DE p75 - Google Patents

NUEVOS DERIVADOS (HETEROCICLO-TETRAHIDRO-PIRIDIN)-(PIPERAZINIL)-1-ALCANONA Y (HETEROCICLO-DIHIDRO-PIRROLIDIN)-(PIPERAZINIL)-1-ALCANONA Y SU UTILIZACIÓN COMO INHIBIDORES DE p75

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Publication number
ECSP12011971A
ECSP12011971A ECSP12011971A ECSP12011971A EC SP12011971 A ECSP12011971 A EC SP12011971A EC SP12011971 A ECSP12011971 A EC SP12011971A EC SP12011971 A ECSP12011971 A EC SP12011971A
Authority
EC
Ecuador
Prior art keywords
alcanona
heterociclo
piperazinil
pirrolidin
tetrahidro
Prior art date
Application number
Other languages
English (en)
Inventor
Françoise Bono
Marco Baroni
Gossart Sandrine Delbary
Valentina Vercesi
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of ECSP12011971A publication Critical patent/ECSP12011971A/es

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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Abstract

La invención se refiere a los derivados (heterociclico-tetrahidro-piridin)-(piperazinil)-1-alcanona y (heterociclo-dihidro-pirrolidin)-(piperazinil)-1-alcanona de la formula general (I) en la que A, B, m, W, n y R2 son tal como se han definido en la reivindicación 1, así como su procedimiento de preparación y su aplicación en tetapéutica.
ECSP12011971 2009-12-14 2012-06-12 NUEVOS DERIVADOS (HETEROCICLO-TETRAHIDRO-PIRIDIN)-(PIPERAZINIL)-1-ALCANONA Y (HETEROCICLO-DIHIDRO-PIRROLIDIN)-(PIPERAZINIL)-1-ALCANONA Y SU UTILIZACIÓN COMO INHIBIDORES DE p75 ECSP12011971A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0906025A FR2953836B1 (fr) 2009-12-14 2009-12-14 Nouveaux derives (heterocycle-tetrahydro-pyridine)-(piperazinyl)-1-alcanone et (heterocycle-dihydro-pyrrolidine)-(piperazinyl)-1-alcanone et leur utilisation comme inhibiteurs de p75

Publications (1)

Publication Number Publication Date
ECSP12011971A true ECSP12011971A (es) 2012-07-31

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ID=41693508

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP12011971 ECSP12011971A (es) 2009-12-14 2012-06-12 NUEVOS DERIVADOS (HETEROCICLO-TETRAHIDRO-PIRIDIN)-(PIPERAZINIL)-1-ALCANONA Y (HETEROCICLO-DIHIDRO-PIRROLIDIN)-(PIPERAZINIL)-1-ALCANONA Y SU UTILIZACIÓN COMO INHIBIDORES DE p75

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EP (1) EP2513088B1 (es)
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DO (1) DOP2012000146A (es)
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EC (1) ECSP12011971A (es)
ES (1) ES2548872T3 (es)
FR (1) FR2953836B1 (es)
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Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2953839A1 (fr) 2009-12-14 2011-06-17 Sanofi Aventis Nouveaux derives d'(heterocycle-piperidine condensee)-(piperazinyl)-1alcanone ou d'(heterocycle-pyrrolidine condensee)-(piperazinyl)-1alcanone et leur utilisation comme inhibiteurs de p75
EP2606894A1 (en) * 2011-12-20 2013-06-26 Sanofi Novel therapeutic use of p75 receptor antagonists
IL326597A (en) 2019-10-07 2026-04-01 Contineum Therapeutics Inc Muscarinic M1 acetylcholine receptor antagonists
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