ECSP13012402A - Inmunoglobulinas con dominio variable dual y su uso - Google Patents

Inmunoglobulinas con dominio variable dual y su uso

Info

Publication number
ECSP13012402A
ECSP13012402A ECSP13012402A ECSP13012402A EC SP13012402 A ECSP13012402 A EC SP13012402A EC SP13012402 A ECSP13012402 A EC SP13012402A EC SP13012402 A ECSP13012402 A EC SP13012402A
Authority
EC
Ecuador
Prior art keywords
immunoglobulins
variable domain
dual variable
dual
multivalent
Prior art date
Application number
Other languages
English (en)
Inventor
James Jakway
Tariq Ghayur
Lorenzo Benatuil
Junjisn Liu
Robert V Talanian
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of ECSP13012402A publication Critical patent/ECSP13012402A/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/64—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a combination of variable region and constant region components

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Abstract

Proteínas de unión multivalentes y multiespecíficas manipuladas, métodos para elaborarlas y, específicamente, sus usos en la prevención, el diagnóstico y/o el tratamiento de enfermedades.
ECSP13012402 2010-06-24 2013-01-22 Inmunoglobulinas con dominio variable dual y su uso ECSP13012402A (es)

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AU (1) AU2011270848A1 (es)
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CA (1) CA2803392A1 (es)
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EC (1) ECSP13012402A (es)
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AR072000A1 (es) 2008-06-03 2010-07-28 Abbott Lab Proteinas de union multivalentes con capacidad de unir dos o mas antigenos y usos de la misma
JP2011523853A (ja) 2008-06-03 2011-08-25 アボット・ラボラトリーズ 二重可変ドメイン免疫グロブリン及びその使用
BRPI0915448A2 (pt) 2008-07-08 2015-11-10 Abbott Lab imunoglobulinas de domínio variável duplo para prostaglandina e2 e usos das mesmas
MX336152B (es) 2009-08-29 2016-01-08 Abbvie Inc Proteinas terapeutico de union a dll4.
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TW201119676A (en) 2009-10-15 2011-06-16 Abbott Lab Dual variable domain immunoglobulins and uses thereof
UY32979A (es) 2009-10-28 2011-02-28 Abbott Lab Inmunoglobulinas con dominio variable dual y usos de las mismas
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CN104159920A (zh) 2011-12-30 2014-11-19 艾伯维公司 针对il-13和/或il-17的双重可变结构域免疫球蛋白
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MY171664A (en) 2012-11-01 2019-10-22 Abbvie Inc Anti-dll4/vegf dual variable domain immunoglobulins and uses thereof
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US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
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TWI725702B (zh) * 2020-01-13 2021-04-21 國立清華大學 收集類澱粉蛋白的系統、其用途及移除類澱粉蛋白的方法
CN115551896B (zh) * 2020-05-15 2026-01-30 神州细胞工程有限公司 通过形成Fc片段融合蛋白糖缀合物增强抗原免疫原性的方法
TWI780616B (zh) 2021-03-04 2022-10-11 國立清華大學 灌流式細胞培養裝置及灌流式細胞培養系統

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TW201204831A (en) 2012-02-01
US20110318349A1 (en) 2011-12-29
EP2585607A2 (en) 2013-05-01
SG188944A1 (en) 2013-05-31
WO2011163478A2 (en) 2011-12-29
RU2013103060A (ru) 2014-07-27
PH12012502523A1 (en) 2013-02-11
PE20130614A1 (es) 2013-07-01
CO6650372A2 (es) 2013-04-15
AU2011270848A1 (en) 2013-02-07
WO2011163478A3 (en) 2012-05-03
CL2012003610A1 (es) 2013-05-17
KR20130043168A (ko) 2013-04-29
BR112012032778A2 (pt) 2019-09-24
ZA201300623B (en) 2014-05-28
CA2803392A1 (en) 2011-12-29
WO2011163478A4 (en) 2012-07-05
CN103200963A (zh) 2013-07-10
EP2585607A4 (en) 2014-01-22

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