ECSP14007092A - Microorganismos modificados y métodos para elaborar butadieno utilizando los mismos - Google Patents

Microorganismos modificados y métodos para elaborar butadieno utilizando los mismos

Info

Publication number
ECSP14007092A
ECSP14007092A ECIEPI20147092A ECPI201407092A ECSP14007092A EC SP14007092 A ECSP14007092 A EC SP14007092A EC IEPI20147092 A ECIEPI20147092 A EC IEPI20147092A EC PI201407092 A ECPI201407092 A EC PI201407092A EC SP14007092 A ECSP14007092 A EC SP14007092A
Authority
EC
Ecuador
Prior art keywords
methods
butadien
prepare
same
modified microorganisms
Prior art date
Application number
ECIEPI20147092A
Other languages
English (en)
Inventor
Lopes Mateus Schreiner Garcez
Lucas Penderson Parizzi
Iuri Estrada Gouvea
Johana Rincones Perez
Avram Michael Slovic
Original Assignee
Braskem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Braskem Sa filed Critical Braskem Sa
Publication of ECSP14007092A publication Critical patent/ECSP14007092A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
    • C12P5/026—Unsaturated compounds, i.e. alkenes, alkynes or allenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01001—Alcohol dehydrogenase (1.1.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C12Y402/01127—Linalool dehydratase (4.2.1.127)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/30—Fuel from waste, e.g. synthetic alcohol or diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

La presente descripción se relaciona en general con microorganismos que comprenden uno o más polinucleótidos que codifican para enzimas en una o más trayectorias que catalizan una conversión de una fuente de carbono fermentable a butadieno. También se proporcionan métodos de uso de microorganismos en procesos industriales, que se incluyen, para uso en la producción de butadieno y productos derivados de los mismos.
ECIEPI20147092A 2011-12-16 2014-06-27 Microorganismos modificados y métodos para elaborar butadieno utilizando los mismos ECSP14007092A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161576788P 2011-12-16 2011-12-16
US201261606035P 2012-03-02 2012-03-02

Publications (1)

Publication Number Publication Date
ECSP14007092A true ECSP14007092A (es) 2015-06-30

Family

ID=48613275

Family Applications (1)

Application Number Title Priority Date Filing Date
ECIEPI20147092A ECSP14007092A (es) 2011-12-16 2014-06-27 Microorganismos modificados y métodos para elaborar butadieno utilizando los mismos

Country Status (14)

Country Link
US (3) US9518273B2 (es)
EP (1) EP2791342B1 (es)
JP (2) JP6415326B2 (es)
KR (1) KR20150068925A (es)
CN (2) CN112877370A (es)
AU (1) AU2012353654B2 (es)
BR (1) BR112014014652B1 (es)
CA (1) CA2859556C (es)
EC (1) ECSP14007092A (es)
MX (1) MX349910B (es)
PH (1) PH12014501364A1 (es)
RU (1) RU2639564C2 (es)
SG (1) SG11201403276TA (es)
WO (1) WO2013090915A1 (es)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9422578B2 (en) 2011-06-17 2016-08-23 Invista North America S.A.R.L. Methods for biosynthesizing 1,3 butadiene
BR112013032516A2 (pt) 2011-06-17 2017-03-01 Invista Tech Sarl método de biosintetizar butadieno e método para produzir butadieno
JP5997939B2 (ja) * 2012-05-31 2016-09-28 株式会社ブリヂストン 共役ジエン系重合体の製造方法
JP5997938B2 (ja) * 2012-05-31 2016-09-28 株式会社ブリヂストン ブタジエン重合体の製造方法及びタイヤの製造方法
WO2013192183A1 (en) * 2012-06-18 2013-12-27 Braskem S/A Ap 09 Modified microorganisms and methods of co-producing butadiene with 1-propanol and/or 1,2-propanediol
US9777295B2 (en) 2012-11-28 2017-10-03 Invista North America S.A.R.L. Methods for biosynthesis of isobutene
US20140206066A1 (en) * 2013-01-18 2014-07-24 Coskata, Inc. Syntrophic co-culture of anaerobic microorganism for production of n-butanol from syngas
US20150050708A1 (en) * 2013-03-15 2015-02-19 Genomatica, Inc. Microorganisms and methods for producing butadiene and related compounds by formate assimilation
WO2014152434A2 (en) * 2013-03-15 2014-09-25 Genomatica, Inc. Microorganisms and methods for producing butadiene and related compounds by formate assimilation
US10294496B2 (en) 2013-07-19 2019-05-21 Invista North America S.A.R.L. Methods for biosynthesizing 1,3 butadiene
WO2015021045A2 (en) 2013-08-05 2015-02-12 INVISTA North America S.á r.l. Methods for biosynthesis of isoprene
WO2015021059A1 (en) 2013-08-05 2015-02-12 INVISTA North America S.á r.l. Methods for biosynthesis of isobutene
WO2015035226A2 (en) * 2013-09-05 2015-03-12 Braskem S/A Modified microorganism and methods of using same for producing 2- propanol and 1-propanol and/or 1.2-propanediol
US10000744B2 (en) 2013-09-23 2018-06-19 Braskem S.A. Engineered enzyme having acetoacetyl-CoA hydrolase activity, microorganisms comprising same, and methods of using same
US9920339B2 (en) 2014-06-16 2018-03-20 Invista North America S.A.R.L. Methods, reagents and cells for biosynthesizing compounds
US10487342B2 (en) 2014-07-11 2019-11-26 Genomatica, Inc. Microorganisms and methods for the production of butadiene using acetyl-CoA
WO2016097293A1 (en) * 2014-12-19 2016-06-23 Global Bioenergies Process for the enzymatic production of 1-butene from 2-pentenoyl-coa
US9938542B2 (en) 2015-02-27 2018-04-10 White Dog Labs, Inc. Mixotrophic fermentation method for making acetone, isopropanol, butyric acid and other bioproducts, and mixtures thereof
CN107750276A (zh) * 2015-04-09 2018-03-02 基因组股份公司 用于改进巴豆醇生产的工程化微生物和方法
WO2016196233A1 (en) 2015-05-30 2016-12-08 Genomatica, Inc. Vinylisomerase-dehydratases, alkenol dehydratases, linalool dehydratases and/ crotyl alcohol dehydratases and methods for making and using them
EP3333263B1 (en) 2015-08-03 2021-12-29 Riken Diphosphomevalonate decarboxylase variant and method for manufacturing olefin compound using same
US20190218578A1 (en) * 2015-08-24 2019-07-18 White Dog Labs, Inc. Microbial organisms for converting acetyl-coa into crotyl alcohol and methods for producing crotyl alcohol
WO2018013701A1 (en) 2016-07-12 2018-01-18 Braskem S.A. Formation of alkenes through enzymatic dehydration of alkanols
KR101929631B1 (ko) 2016-12-20 2018-12-14 서강대학교산학협력단 미생물 발효를 이용한 1,3-부타디엔의 제조 방법
US11162115B2 (en) 2017-06-30 2021-11-02 Inv Nylon Chemicals Americas, Llc Methods, synthetic hosts and reagents for the biosynthesis of hydrocarbons
WO2019006255A1 (en) 2017-06-30 2019-01-03 Invista North America S.A.R.L. METHODS, MATERIALS, SYNTHETIC HOSTS AND REAGENTS FOR HYDROCARBON BIOSYNTHESIS AND DERIVATIVES
US11505809B2 (en) 2017-09-28 2022-11-22 Inv Nylon Chemicals Americas Llc Organisms and biosynthetic processes for hydrocarbon synthesis
CN108690851B (zh) * 2018-05-30 2020-11-06 青岛农业大学 一种丁二烯生产菌及其生产丁二烯的方法
CN108949788B (zh) * 2018-07-10 2020-07-14 广东省微生物研究所（广东省微生物分析检测中心） 番茄红素合成相关基因及其应用
CN109666683B (zh) * 2019-02-27 2021-10-29 昆明理工大学 乙酰辅酶A乙酰转移酶基因RKAcaT2及其应用
CN110433619B (zh) * 2019-09-05 2021-11-16 北京工商大学 杀鲑气单胞菌亚种在挥发性有机污染物降解方面的应用
JP7761892B2 (ja) 2023-06-15 2025-10-29 株式会社Ｃｏ２資源化研究所 クロチルアルコールを生成するヒドロゲノフィラス属細菌形質転換体
WO2025059545A1 (en) * 2023-09-13 2025-03-20 The Fynder Group, Inc. Biomaterial-based elastomeric materials

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US30985A (en) 1860-12-18 Thomas l
US4560655A (en) 1982-12-16 1985-12-24 Immunex Corporation Serum-free cell culture medium and process for making same
US4657866A (en) 1982-12-21 1987-04-14 Sudhir Kumar Serum-free, synthetic, completely chemically defined tissue culture media
DD266710A3 (de) 1983-06-06 1989-04-12 Ve Forschungszentrum Biotechnologie Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase
US4767704A (en) 1983-10-07 1988-08-30 Columbia University In The City Of New York Protein-free culture medium
US4879231A (en) 1984-10-30 1989-11-07 Phillips Petroleum Company Transformation of yeasts of the genus pichia
GB8516415D0 (en) 1985-06-28 1985-07-31 Celltech Ltd Culture of animal cells
US4927762A (en) 1986-04-01 1990-05-22 Cell Enterprises, Inc. Cell culture medium with antioxidant
GB8610600D0 (en) 1986-04-30 1986-06-04 Novo Industri As Transformation of trichoderma
IL87737A (en) 1987-09-11 1993-08-18 Genentech Inc Method for culturing polypeptide factor dependent vertebrate recombinant cells
EP0402226A1 (en) 1989-06-06 1990-12-12 Institut National De La Recherche Agronomique Transformation vectors for yeast yarrowia
SE464472B (sv) 1989-08-31 1991-04-29 Aga Ab Saett och anordning foer tillverkning av ihaaliga foeremaal av glas
US5122469A (en) 1990-10-03 1992-06-16 Genentech, Inc. Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins
DE102004054766A1 (de) * 2004-11-12 2006-05-18 Basf Ag Verfahren zur Herstellung von Butadien aus n-Butan
CA2715093A1 (en) * 2006-12-01 2008-11-27 Gevo, Inc. Engineered microorganisms for producing n-butanol and related methods
US7981647B2 (en) * 2008-03-03 2011-07-19 Joule Unlimited, Inc. Engineered CO2 fixing microorganisms producing carbon-based products of interest
ES2647785T3 (es) 2008-07-04 2017-12-26 Scientist Of Fortune S.A. Producción de alquenos mediante descarboxilación enzimática de ácidos 3-hidroxi-alcanoicos
SG179048A1 (en) * 2009-09-09 2012-04-27 Genomatica Inc Microorganisms and methods for the co-production of isopropanol with primary alcohols, diols and acids
US8410326B2 (en) * 2010-01-14 2013-04-02 Wisconsin Alumni Research Foundation Integrated process and apparatus to produce hydrocarbons from aqueous solutions of lactones, hydroxy-carboxylic acids, alkene-carboxylic acids, and/or alcohols
EP2566969B1 (en) * 2010-05-05 2019-09-04 Genomatica, Inc. Microorganisms and methods for the biosynthesis of butadiene
CN103025877A (zh) 2010-07-26 2013-04-03 基因组股份公司 用于生物合成芳族化合物、2,4-戊二烯酸和1,3-丁二烯的微生物和方法
US9422578B2 (en) * 2011-06-17 2016-08-23 Invista North America S.A.R.L. Methods for biosynthesizing 1,3 butadiene
US10808262B2 (en) * 2013-12-03 2020-10-20 Genomatica, Inc. Microorganisms and methods for improving product yields on methanol using acetyl-CoA synthesis
US10487342B2 (en) * 2014-07-11 2019-11-26 Genomatica, Inc. Microorganisms and methods for the production of butadiene using acetyl-CoA

Also Published As

Publication number Publication date
MX2014007235A (es) 2015-04-13
AU2012353654A8 (en) 2014-07-17
US10059963B2 (en) 2018-08-28
AU2012353654A1 (en) 2014-07-10
RU2639564C2 (ru) 2017-12-21
AU2012353654B2 (en) 2016-09-29
JP6415326B2 (ja) 2018-10-31
RU2014129026A (ru) 2016-02-10
EP2791342A4 (en) 2016-04-13
EP2791342A1 (en) 2014-10-22
BR112014014652A8 (pt) 2017-06-13
US20160032325A1 (en) 2016-02-04
KR20150068925A (ko) 2015-06-22
JP2018134113A (ja) 2018-08-30
JP2015501659A (ja) 2015-01-19
WO2013090915A1 (en) 2013-06-20
US10273505B2 (en) 2019-04-30
BR112014014652A2 (pt) 2017-06-13
US20180346936A1 (en) 2018-12-06
PH12014501364A1 (en) 2014-09-22
MX349910B (es) 2017-08-17
CN104471068A (zh) 2015-03-25
EP2791342B1 (en) 2020-04-29
CA2859556C (en) 2022-01-11
CN112877370A (zh) 2021-06-01
US20150152439A2 (en) 2015-06-04
SG11201403276TA (en) 2014-10-30
US20140370564A1 (en) 2014-12-18
US9518273B2 (en) 2016-12-13
CA2859556A1 (en) 2013-06-20
BR112014014652B1 (pt) 2021-07-13

Similar Documents

Publication Publication Date Title
ECSP14007092A (es) Microorganismos modificados y métodos para elaborar butadieno utilizando los mismos
PH12018501397A1 (en) Processing biomass
CO6351813A2 (es) "metodos y composiciones para mejorar la produccion de productos en microorganismos"
PH12014500588A1 (en) Microorganisms and methods for producing alkenes
SG10201804869UA (en) Purification of biological molecules
IN2015DN01365A (es)
MX2016014235A (es) Biosintesis microbiana de ergotioneina.
AU2011372711B2 (en) Method for processing mesenchymal stem cells and the use thereof in the treatment of diseases associated with oxidative stress
IN2014DN09244A (es)
BR112013031414A2 (pt) métodos para converter material lignocelulósico em produtos úteis
GEP20186826B (en) Intermediate product for treprostinil synthesis and methods for preparation thereof
MX2012002019A (es) Sistema de placa de pozos profundos con tapa.
ECSP13013036A (es) Alfa glucosidasa ácida modificada con procesamiento acelerado
WO2013105827A3 (ko) 퓨트레신 생산능이 향상된 재조합 미생물 및 이를 이용하여 퓨트레신을 생산하는 방법
EA201171364A1 (ru) Ферментный комплекс
MY182946A (en) Production of organic acids by fermentation at low ph
MX2016002651A (es) Microorganismo modificado para la produccion mejorada de alanina.
WO2016094877A3 (en) High solids enzymatic hydrolysis and fermentation of pretreated biomass
EA201591197A1 (ru) Способ получения алкилметакрилата
WO2014049382A3 (en) Ethylenediamine fermentative production by a recombinant microorganism
EA201290801A1 (ru) Способ получения сциллоинозита
IN2014MN01621A (es)
WO2014036140A3 (en) Methods for production of a terpene and a co-product
WO2012068537A3 (en) New biocatalysts and primers for production of chemicals
WO2014063156A3 (en) Modified microorganisms and methods of using same for producing butadiene and one or more of 1,3-butanediol, 1,4-butanediol, and/or 1,3-propanediol