ECSP14013132A - Anticuerpos anti-psgl-1 y usos de los mismos - Google Patents

Anticuerpos anti-psgl-1 y usos de los mismos

Info

Publication number
ECSP14013132A
ECSP14013132A ECSP14013132A ECSP14013132A EC SP14013132 A ECSP14013132 A EC SP14013132A EC SP14013132 A ECSP14013132 A EC SP14013132A EC SP14013132 A ECSP14013132 A EC SP14013132A
Authority
EC
Ecuador
Prior art keywords
antibodies
psgl
same
cells
here
Prior art date
Application number
Other languages
English (en)
Inventor
Sanjaya Singh
Tobias Litzenburger
Stefan Bassarab
Barbara Enenkel
Patrick Garidel
Heidrun Schott
Original Assignee
Abgenomics Cooperatief Ua
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47357432&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP14013132(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abgenomics Cooperatief Ua filed Critical Abgenomics Cooperatief Ua
Publication of ECSP14013132A publication Critical patent/ECSP14013132A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • C07K2317/53Hinge

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Mycology (AREA)
  • Emergency Medicine (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Aquí se proporciona, en un aspecto, anticuerpos que se unen inmunoespecíficamente a PSGL-1, polinucleótidos que comprenden secuencias de nucleótido que codifican a tales anticuerpos, y los vectores de expresión y células huésped para producir a tales anticuerpos. También se proveen aquí los kits y las composiciones farmacéuticas que comprenden los anticuerpos que se unen específicamente a PSGL-1, así como los métodos para tratar un desorden o enfermedad causado por o asociado con la proliferación aumentada y/o cantidades aumentadas de células T activadas usando los anticuerpos aquí descritos.
ECSP14013132 2011-06-13 2014-01-13 Anticuerpos anti-psgl-1 y usos de los mismos ECSP14013132A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161496249P 2011-06-13 2011-06-13

Publications (1)

Publication Number Publication Date
ECSP14013132A true ECSP14013132A (es) 2015-04-30

Family

ID=47357432

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP14013132 ECSP14013132A (es) 2011-06-13 2014-01-13 Anticuerpos anti-psgl-1 y usos de los mismos

Country Status (21)

Country Link
US (4) US20130209449A9 (es)
EP (2) EP3925978A1 (es)
JP (1) JP6180408B2 (es)
KR (1) KR102103036B1 (es)
CN (3) CN116063522A (es)
AU (1) AU2012271845B2 (es)
BR (1) BR112013031892A2 (es)
CA (1) CA2838952C (es)
CL (1) CL2013003570A1 (es)
CO (1) CO6940376A2 (es)
EC (1) ECSP14013132A (es)
IL (2) IL229844B (es)
MX (1) MX358447B (es)
NZ (1) NZ619524A (es)
PH (1) PH12013502568B1 (es)
RU (1) RU2650817C2 (es)
SG (1) SG10201604767TA (es)
TW (1) TWI643872B (es)
UA (1) UA114712C2 (es)
WO (1) WO2012174001A1 (es)
ZA (1) ZA201400209B (es)

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CN106659784B (zh) * 2014-07-08 2022-03-29 桑福德伯纳姆医学研究所 Psgl-1调控剂及其用途
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CN113667015B (zh) * 2021-08-20 2022-10-11 北京康特泊瑞生物医药科技股份公司 靶向psgl-1蛋白的抗体及其用途
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CN120265323A (zh) * 2022-09-13 2025-07-04 泰克斯制药公司 抗体、组合物和治疗方法
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Also Published As

Publication number Publication date
US20130209449A9 (en) 2013-08-15
EP3925978A1 (en) 2021-12-22
AU2012271845B2 (en) 2017-07-27
CO6940376A2 (es) 2014-05-09
NZ619524A (en) 2016-10-28
KR102103036B1 (ko) 2020-04-22
US20130251708A1 (en) 2013-09-26
JP2014519524A (ja) 2014-08-14
AU2012271845A1 (en) 2014-01-23
KR20140066153A (ko) 2014-05-30
ZA201400209B (en) 2020-05-27
US20130011391A1 (en) 2013-01-10
IL287270A (en) 2021-12-01
PH12013502568A1 (en) 2014-01-27
CN116063522A (zh) 2023-05-05
IL229844B (en) 2022-02-01
EP2718325A1 (en) 2014-04-16
PH12013502568B1 (en) 2018-08-10
CA2838952C (en) 2020-11-24
EP2718325A4 (en) 2015-03-11
CL2013003570A1 (es) 2014-08-22
MX2013014814A (es) 2014-07-22
BR112013031892A2 (pt) 2016-11-22
US20240124604A1 (en) 2024-04-18
RU2650817C2 (ru) 2018-04-17
CN108892726A (zh) 2018-11-27
US11897964B2 (en) 2024-02-13
CA2838952A1 (en) 2012-12-20
SG10201604767TA (en) 2016-08-30
CN103732626A (zh) 2014-04-16
TW201302791A (zh) 2013-01-16
US20210395383A1 (en) 2021-12-23
TWI643872B (zh) 2018-12-11
WO2012174001A1 (en) 2012-12-20
MX358447B (es) 2018-08-21
UA114712C2 (uk) 2017-07-25
RU2013158083A (ru) 2015-09-20
JP6180408B2 (ja) 2017-08-16

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