ECSP22054471A - Anticuerpo multiespec?fico con especificidad de uni?n para il-13 e il-17 humanas - Google Patents

Anticuerpo multiespec?fico con especificidad de uni?n para il-13 e il-17 humanas

Info

Publication number
ECSP22054471A
ECSP22054471A ECSENADI202254471A ECDI202254471A ECSP22054471A EC SP22054471 A ECSP22054471 A EC SP22054471A EC SENADI202254471 A ECSENADI202254471 A EC SENADI202254471A EC DI202254471 A ECDI202254471 A EC DI202254471A EC SP22054471 A ECSP22054471 A EC SP22054471A
Authority
EC
Ecuador
Prior art keywords
human
multispecific antibody
binding specificity
specificity
relates
Prior art date
Application number
ECSENADI202254471A
Other languages
English (en)
Inventor
Adnan Rahman Khan
Sam Philip Heywood
David Paul Humphreys
Emma Dave
Sarah Jayne Stanyon
Daniel John Lightwood
Emily Mary Cairistine Barry
Original Assignee
UCB Biopharma SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UCB Biopharma SRL filed Critical UCB Biopharma SRL
Publication of ECSP22054471A publication Critical patent/ECSP22054471A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La presente invenci?n se refiere a un anticuerpo multiespec?fico que tiene especificidad para IL-13 humana, IL-17A humana y/o IL-17F humana. La invenci?n se refiere adem?s a m?todos para producir el anticuerpo multiespec?fico y a su uso terap?utico para el tratamiento de la dermatitis at?pica y otras enfermedades.
ECSENADI202254471A 2019-12-20 2022-07-13 Anticuerpo multiespec?fico con especificidad de uni?n para il-13 e il-17 humanas ECSP22054471A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1919061.0A GB201919061D0 (en) 2019-12-20 2019-12-20 Multi-specific antibody

Publications (1)

Publication Number Publication Date
ECSP22054471A true ECSP22054471A (es) 2022-08-31

Family

ID=69323008

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSENADI202254471A ECSP22054471A (es) 2019-12-20 2022-07-13 Anticuerpo multiespec?fico con especificidad de uni?n para il-13 e il-17 humanas

Country Status (19)

Country Link
US (2) US12570738B2 (es)
EP (1) EP4077381A1 (es)
JP (1) JP7689125B2 (es)
KR (1) KR20220117307A (es)
CN (3) CN122541578A (es)
AR (1) AR120818A1 (es)
AU (1) AU2020407279A1 (es)
BR (1) BR112022011627A2 (es)
CA (1) CA3164276A1 (es)
CL (2) CL2022001685A1 (es)
CO (1) CO2022009711A2 (es)
EC (1) ECSP22054471A (es)
GB (1) GB201919061D0 (es)
IL (1) IL294035A (es)
MX (1) MX2022007150A (es)
PE (1) PE20221173A1 (es)
PH (1) PH12022551411A1 (es)
WO (1) WO2021123186A1 (es)
ZA (1) ZA202207715B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017189805A1 (en) 2016-04-27 2017-11-02 Abbvie Inc. Methods of treatment of diseases in which il-13 activity is detrimental using anti-il-13 antibodies
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Also Published As

Publication number Publication date
TW202130365A (zh) 2021-08-16
EP4077381A1 (en) 2022-10-26
IL294035A (en) 2022-08-01
BR112022011627A2 (pt) 2022-09-13
CN114846026B (zh) 2026-05-15
JP7689125B2 (ja) 2025-06-05
PH12022551411A1 (en) 2023-11-20
GB201919061D0 (en) 2020-02-05
CA3164276A1 (en) 2021-06-24
PE20221173A1 (es) 2022-07-25
US20230087378A1 (en) 2023-03-23
AU2020407279A1 (en) 2022-08-11
MX2022007150A (es) 2022-07-19
KR20220117307A (ko) 2022-08-23
US20260226151A1 (en) 2026-08-06
CO2022009711A2 (es) 2022-07-19
ZA202207715B (en) 2024-01-31
CL2022001685A1 (es) 2023-05-26
US12570738B2 (en) 2026-03-10
CL2023002975A1 (es) 2024-04-01
WO2021123186A1 (en) 2021-06-24
CN122502498A (zh) 2026-08-04
CN114846026A (zh) 2022-08-02
CN122541578A (zh) 2026-08-11
JP2023507280A (ja) 2023-02-22
AR120818A1 (es) 2022-03-23

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