ECSP951557A - Analogos composiciones y procedimientos de uso de peptidos insulinotropicos similares al glucagon - Google Patents
Analogos composiciones y procedimientos de uso de peptidos insulinotropicos similares al glucagonInfo
- Publication number
- ECSP951557A ECSP951557A ECSP951557A ECSP951557A EC SP951557 A ECSP951557 A EC SP951557A EC SP951557 A ECSP951557 A EC SP951557A EC SP951557 A ECSP951557 A EC SP951557A
- Authority
- EC
- Ecuador
- Prior art keywords
- glucagon
- procedures
- analogs
- insulinotropic peptides
- compositions
- Prior art date
Links
- 230000002473 insulinotropic effect Effects 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
- 102000004877 Insulin Human genes 0.000 abstract 1
- 108090001061 Insulin Proteins 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 210000000227 basophil cell of anterior lobe of hypophysis Anatomy 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940125396 insulin Drugs 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- 238000011191 terminal modification Methods 0.000 abstract 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
El invento se refiere a análogos y derivados de péptidos insulinotrópicos similares al glucagón (GLP-(7-37). Los análogos incluyen sustituciones de aminoácidos, modificaciones del terminal amino y carboxilo y acilaciones de C6-C10. Los compuestos reivindicados estimulan la secreción o biosintesis de insulina en células beta con baja acción y son por lo tanto útiles en el tratamiento de los diabéticos tipo II.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP951557 ECSP951557A (es) | 1995-10-17 | 1995-10-17 | Analogos composiciones y procedimientos de uso de peptidos insulinotropicos similares al glucagon |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP951557 ECSP951557A (es) | 1995-10-17 | 1995-10-17 | Analogos composiciones y procedimientos de uso de peptidos insulinotropicos similares al glucagon |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP951557A true ECSP951557A (es) | 1997-07-28 |
Family
ID=42042199
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP951557 ECSP951557A (es) | 1995-10-17 | 1995-10-17 | Analogos composiciones y procedimientos de uso de peptidos insulinotropicos similares al glucagon |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP951557A (es) |
-
1995
- 1995-10-17 EC ECSP951557 patent/ECSP951557A/es unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE285473T1 (de) | Glucagon-ähnliche insulinotrope peptid-analoge, zusammensetzungen und verwendungsverfahren | |
| PT699686E (pt) | Fragmentos de peptido insulinotropico do tipo glucagona biologicamente activos | |
| DE69129226D1 (de) | Glp-1-analoga verwendbar in der diabetesbehandlung | |
| ES2351661T3 (es) | Péptido-2 análogo al glucagón. | |
| ATE193541T1 (de) | Insulinotropes hormon | |
| RU2208015C2 (ru) | Аналоги гпп-1 | |
| ES2334864T3 (es) | Peptido-2 analogo al glucagon y su uso terapeutico. | |
| MX9303554A (es) | Peptido similar al glucagon y derivados de insulinotropina. | |
| ZA202306729B (en) | Novel glp-1 analogues | |
| AR019806A1 (es) | Cristales de glp de morfologia semejante a placas o varillas planas tetragonales; composiciones sustancialmente homogeneas de dichos cristales;formulaciones farmaceuticas que comprenden cristales de glp que comprenden a una de dichas morfologias; procedimiento para preparar dichos cristales deglp y | |
| DE68928810D1 (de) | Analoge vom menschlichen Insulin | |
| ES2153367T3 (es) | Derivados de clorofila y de bacterioclorofila, su preparacion y composiciones farmaceuticas que los contienen. | |
| MD960317A (ro) | Noile peptide-agoniste ale amilinei şi utilizarea lor | |
| AR247590A1 (es) | Una secuencia de adn que codifica derivados de factor viii humano recombinante y un procedimiento para su obtencion | |
| KR20150088294A (ko) | 인슐린 저항성에 대한 개선된 펩티드 약제 | |
| DK169784A (da) | Peptider til farmaceutisk behandling af pattedyr | |
| DE69838647D1 (de) | Behandlung von fettleibigkeit | |
| Irwin et al. | Antidiabetic potential of two novel fatty acid derivatised, N-terminally modified analogues of glucose-dependent insulinotropic polypeptide (GIP): N-AcGIP (LysPAL 16) and N-AcGIP (LysPAL 37). | |
| US20090281032A1 (en) | Modified CCK peptides | |
| EP2384338A2 (en) | Glp-1 analogs and uses thereof | |
| EA202092017A1 (ru) | Новые аналоги glp-1 | |
| HK40044876A (en) | Novel glp-1 analogues | |
| HK40044876B (en) | Novel glp-1 analogues |