ECSP961684A - DERIVATIVES OF ACID ARILSULFONILAMINO HIDROXAMICO - Google Patents
DERIVATIVES OF ACID ARILSULFONILAMINO HIDROXAMICOInfo
- Publication number
- ECSP961684A ECSP961684A ECSP961684A ECSP961684A EC SP961684 A ECSP961684 A EC SP961684A EC SP961684 A ECSP961684 A EC SP961684A EC SP961684 A ECSP961684 A EC SP961684A
- Authority
- EC
- Ecuador
- Prior art keywords
- derivatives
- acid
- hidroxamico
- arilsulfonilamino
- production
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 102100040247 Tumor necrosis factor Human genes 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 208000030507 AIDS Diseases 0.000 abstract 1
- 206010014989 Epidermolysis bullosa Diseases 0.000 abstract 1
- 102000002274 Matrix Metalloproteinases Human genes 0.000 abstract 1
- 108010000684 Matrix Metalloproteinases Proteins 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 206010039705 Scleritis Diseases 0.000 abstract 1
- 206010040047 Sepsis Diseases 0.000 abstract 1
- 206010040070 Septic Shock Diseases 0.000 abstract 1
- 108060008682 Tumor Necrosis Factor Proteins 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 206010003246 arthritis Diseases 0.000 abstract 1
- 125000004657 aryl sulfonyl amino group Chemical group 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 208000028169 periodontal disease Diseases 0.000 abstract 1
- 208000037803 restenosis Diseases 0.000 abstract 1
- 230000036303 septic shock Effects 0.000 abstract 1
- 230000036269 ulceration Effects 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente invención se refiere a derivados delo ácido arilsulfonilamino hidroxímico que son inhibidores de las metas loproteasas de la matriz o de la producción del factor de necrosis tumoral (denominado en lo sucesivo FNT) y, que como tal, son útiles en el tratamiento de un estado seleccionado a partir del grupo que consiste en artritis, cáncer, ulceración tisular, reestenosis, enfermedad periodontal, epidermólisis bullosa, escleritis y otras enfermedades caracterizadas por la actividad de las metaloproteinasas de la matriz, sida, sepsis, choque séptico y otras enfermedades que implican la producción del FNT.The present invention relates to derivatives of arylsulfonylamino hydroxymic acid which are inhibitors of the meta-loprotease targets of the matrix or of the production of tumor necrosis factor (hereinafter referred to as TNF) and which, as such, are useful in the treatment of a status selected from the group consisting of arthritis, cancer, tissue ulceration, restenosis, periodontal disease, epidermolysis bullosa, scleritis, and other diseases characterized by the activity of matrix metalloproteinases, AIDS, sepsis, septic shock, and other diseases involving FNT production.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP961684 ECSP961684A (en) | 1996-03-08 | 1996-03-08 | DERIVATIVES OF ACID ARILSULFONILAMINO HIDROXAMICO |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP961684 ECSP961684A (en) | 1996-03-08 | 1996-03-08 | DERIVATIVES OF ACID ARILSULFONILAMINO HIDROXAMICO |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP961684A true ECSP961684A (en) | 1997-09-22 |
Family
ID=42042417
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP961684 ECSP961684A (en) | 1996-03-08 | 1996-03-08 | DERIVATIVES OF ACID ARILSULFONILAMINO HIDROXAMICO |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP961684A (en) |
-
1996
- 1996-03-08 EC ECSP961684 patent/ECSP961684A/en unknown
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