ECSP961719A - DERIVATIVES OF ACID ARIL SULFONIL HIDROXAMICO - Google Patents
DERIVATIVES OF ACID ARIL SULFONIL HIDROXAMICOInfo
- Publication number
- ECSP961719A ECSP961719A ECSP961719A ECSP961719A EC SP961719 A ECSP961719 A EC SP961719A EC SP961719 A ECSP961719 A EC SP961719A EC SP961719 A ECSP961719 A EC SP961719A
- Authority
- EC
- Ecuador
- Prior art keywords
- derivatives
- hidroxamico
- sulfonil
- aril
- acid
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 102100040247 Tumor necrosis factor Human genes 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000030507 AIDS Diseases 0.000 abstract 1
- 206010053177 Epidermolysis Diseases 0.000 abstract 1
- 102000002274 Matrix Metalloproteinases Human genes 0.000 abstract 1
- 108010000684 Matrix Metalloproteinases Proteins 0.000 abstract 1
- 102000005741 Metalloproteases Human genes 0.000 abstract 1
- 108010006035 Metalloproteases Proteins 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 206010039705 Scleritis Diseases 0.000 abstract 1
- 206010040047 Sepsis Diseases 0.000 abstract 1
- 206010040070 Septic Shock Diseases 0.000 abstract 1
- 108060008682 Tumor Necrosis Factor Proteins 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 206010003246 arthritis Diseases 0.000 abstract 1
- -1 arylsulfonyl hydroxamic Chemical compound 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 208000028169 periodontal disease Diseases 0.000 abstract 1
- 208000037803 restenosis Diseases 0.000 abstract 1
- 230000036303 septic shock Effects 0.000 abstract 1
- 208000013223 septicemia Diseases 0.000 abstract 1
- 102000003390 tumor necrosis factor Human genes 0.000 abstract 1
- 230000036269 ulceration Effects 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Esta invención se refiere a derivados del ácido arilsulfonil hidroxámico que son inhibidores de metaloproteinasas de la matriz o de la producción del factor de necrosis de tumor (a partir de aquí denominado TNF) y como tales son útiles en el tratamiento de un transtorno seleccionado entre el grupo formado por artritis, cáncer, ulceración de tejidos, reestenosis, enfermedad periodontal, epidermólisis vesicular, escleritis y otras enfermedades caracterizadas por actividad de metaloproteinasa en la matriz, asi como SIDA, septicemia, choque séptico y otras enfermedades que impliquen la producción de TNF.This invention relates to arylsulfonyl hydroxamic acid derivatives that are inhibitors of matrix metalloproteinases or of the production of tumor necrosis factor (hereinafter called TNF) and as such are useful in the treatment of a disorder selected from the group formed by arthritis, cancer, tissue ulceration, restenosis, periodontal disease, vesicular epidermolysis, scleritis and other diseases characterized by metalloproteinase activity in the womb, as well as AIDS, septicemia, septic shock and other diseases that involve the production of TNF.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP961719 ECSP961719A (en) | 1996-04-12 | 1996-04-12 | DERIVATIVES OF ACID ARIL SULFONIL HIDROXAMICO |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP961719 ECSP961719A (en) | 1996-04-12 | 1996-04-12 | DERIVATIVES OF ACID ARIL SULFONIL HIDROXAMICO |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP961719A true ECSP961719A (en) | 1997-09-09 |
Family
ID=42042449
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP961719 ECSP961719A (en) | 1996-04-12 | 1996-04-12 | DERIVATIVES OF ACID ARIL SULFONIL HIDROXAMICO |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP961719A (en) |
-
1996
- 1996-04-12 EC ECSP961719 patent/ECSP961719A/en unknown
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