ECSP982444A - PHARMACEUTICAL COMPOSITIONS - Google Patents
PHARMACEUTICAL COMPOSITIONSInfo
- Publication number
- ECSP982444A ECSP982444A ECSP982444A ECSP982444A EC SP982444 A ECSP982444 A EC SP982444A EC SP982444 A ECSP982444 A EC SP982444A EC SP982444 A ECSP982444 A EC SP982444A
- Authority
- EC
- Ecuador
- Prior art keywords
- fatty acid
- hydrophilic
- mixture
- cyclosporin
- pharmaceutical compositions
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 2
- 229930105110 Cyclosporin A Natural products 0.000 abstract 2
- 108010036949 Cyclosporine Proteins 0.000 abstract 2
- 229960001265 ciclosporin Drugs 0.000 abstract 2
- 229930182912 cyclosporin Natural products 0.000 abstract 2
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 2
- 229930195729 fatty acid Natural products 0.000 abstract 2
- 239000000194 fatty acid Substances 0.000 abstract 2
- 150000004665 fatty acids Chemical class 0.000 abstract 2
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 abstract 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000004667 medium chain fatty acids Chemical class 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 150000003138 primary alcohols Chemical class 0.000 abstract 1
- RUOJZAUFBMNUDX-UHFFFAOYSA-N propylene carbonate Chemical compound CC1COC(=O)O1 RUOJZAUFBMNUDX-UHFFFAOYSA-N 0.000 abstract 1
- 239000007901 soft capsule Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención se refiere a una preparación de cápsula blanda que contiene ciclosporina, la cual comprende una composición que contiene ciclosporina como ingrediente activo: un componente hidrofílico de glicol de polietileno, o un componente no hidrofilico de carbonato de propileno o su mezcla, uno o una mezcla de dos o más seleccionados a partir del grupo que consiste en un compuesto esterificado de ácido graso y alcohol primario, triglicérido de ácido graso de cadena mediana, y monoglicérido de ácido graso como un componente de aceite; y un tenso activo que tiene un valor HLB (Equilibrio Hidrofilico-Lipofilico) de 8 a 17.The present invention relates to a cyclosporin-containing soft capsule preparation, which comprises a composition containing cyclosporin as the active ingredient: a hydrophilic component of polyethylene glycol, or a non-hydrophilic component of propylene carbonate or its mixture, one or a mixture of two or more selected from the group consisting of an esterified compound of fatty acid and primary alcohol, medium chain fatty acid triglyceride, and fatty acid monoglyceride as an oil component; and an active surfactant that has an HLB (Hydrophilic-Lipophilic Balance) value of 8 to 17.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP982444 ECSP982444A (en) | 1998-03-12 | 1998-03-12 | PHARMACEUTICAL COMPOSITIONS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP982444 ECSP982444A (en) | 1998-03-12 | 1998-03-12 | PHARMACEUTICAL COMPOSITIONS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP982444A true ECSP982444A (en) | 1999-01-12 |
Family
ID=42043366
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP982444 ECSP982444A (en) | 1998-03-12 | 1998-03-12 | PHARMACEUTICAL COMPOSITIONS |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP982444A (en) |
-
1998
- 1998-03-12 EC ECSP982444 patent/ECSP982444A/en unknown
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