ECSP993136A - 4- CARBOXYAMINE- 2- METHYL- 1,2,3,4- TETRAHYDROKINOLINS - Google Patents
4- CARBOXYAMINE- 2- METHYL- 1,2,3,4- TETRAHYDROKINOLINSInfo
- Publication number
- ECSP993136A ECSP993136A ECSP993136A ECSP993136A EC SP993136 A ECSP993136 A EC SP993136A EC SP993136 A ECSP993136 A EC SP993136A EC SP993136 A ECSP993136 A EC SP993136A
- Authority
- EC
- Ecuador
- Prior art keywords
- cholesterol
- inhibitors
- levels
- triglycerides
- tetrahydrokinolins
- Prior art date
Links
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- 150000002632 lipids Chemical class 0.000 abstract 2
- 150000003626 triacylglycerols Chemical class 0.000 abstract 2
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 108010023302 HDL Cholesterol Proteins 0.000 abstract 1
- 108010028554 LDL Cholesterol Proteins 0.000 abstract 1
- 238000008214 LDL Cholesterol Methods 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- 239000003354 cholesterol ester transfer protein inhibitor Substances 0.000 abstract 1
- 108010022197 lipoprotein cholesterol Proteins 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
El invento se refiere a inhibidores de la proteína de transferencia del éster colesterílico, composiciones farmacéuticas que contienen dichos inhibidores y el uso de dichos inhibidores para elevar ciertos niveles de lípidos en plasma, incluyendo lipoproteínas de alta densidad de colestrol y para disminuir ciertos otros niveles de lípidos en plasma, tales como LDL-colesterol y triglicéridos, y por consiguiente para tratar enfermedades que son excerbadas por bajos niveles de HDL-colesterol y triglicéridos, tales como aterosclerósis y enfermedades an algunos mamiferos incluyendo seres humanos.The invention relates to cholesteryl ester transfer protein inhibitors, pharmaceutical compositions containing such inhibitors, and the use of said inhibitors to raise certain plasma lipid levels, including high cholesterol cholesterol lipoproteins and to decrease certain other levels of plasma lipids, such as LDL-cholesterol and triglycerides, and therefore to treat diseases that are exacerbated by low levels of HDL-cholesterol and triglycerides, such as atherosclerosis and diseases in some mammals including humans.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP993136 ECSP993136A (en) | 1999-09-10 | 1999-09-10 | 4- CARBOXYAMINE- 2- METHYL- 1,2,3,4- TETRAHYDROKINOLINS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP993136 ECSP993136A (en) | 1999-09-10 | 1999-09-10 | 4- CARBOXYAMINE- 2- METHYL- 1,2,3,4- TETRAHYDROKINOLINS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP993136A true ECSP993136A (en) | 1999-10-29 |
Family
ID=42044124
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP993136 ECSP993136A (en) | 1999-09-10 | 1999-09-10 | 4- CARBOXYAMINE- 2- METHYL- 1,2,3,4- TETRAHYDROKINOLINS |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP993136A (en) |
-
1999
- 1999-09-10 EC ECSP993136 patent/ECSP993136A/en unknown
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