ECSP993135A - 1,2,3,4- TETRAHIDROQUINOLINAS -2-SUBSTITUTED 4- AMINO SUBSTITUTED - Google Patents
1,2,3,4- TETRAHIDROQUINOLINAS -2-SUBSTITUTED 4- AMINO SUBSTITUTEDInfo
- Publication number
- ECSP993135A ECSP993135A ECSP993135A ECSP993135A EC SP993135 A ECSP993135 A EC SP993135A EC SP993135 A ECSP993135 A EC SP993135A EC SP993135 A ECSP993135 A EC SP993135A
- Authority
- EC
- Ecuador
- Prior art keywords
- substituted
- inhibitors
- levels
- cholesterol
- plasma lipid
- Prior art date
Links
- 238000008214 LDL Cholesterol Methods 0.000 abstract 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- 150000002632 lipids Chemical class 0.000 abstract 2
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 108010023302 HDL Cholesterol Proteins 0.000 abstract 1
- 108010010234 HDL Lipoproteins Proteins 0.000 abstract 1
- 102000015779 HDL Lipoproteins Human genes 0.000 abstract 1
- 241000282414 Homo sapiens Species 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- 239000003354 cholesterol ester transfer protein inhibitor Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003626 triacylglycerols Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Inhibidores de la proteína de transferencia de colesteril éster, composiciones farmacéuticas que contienen tales inhibidores y el uso de tales inhibidores para elevar ciertos niveles de lípidos en plasma, incluyendo colesterol de lipoproteínas de alta densidad, y para reducir ciertos otros niveles de lípidos en plasma, tales como el colesterol LDL y los triglicériodos y, por consiguiente, para tratar enfermedades que se exacerban por los bajos niveles de colesterol HDL y/o altos niveles de colesterol LDL y triglicéridos, tales como la aterosclerósis y enfermedades cardiovasculares en algunos mamíferos, incluyendo los seres humanos.Cholesteryl ester transfer protein inhibitors, pharmaceutical compositions containing such inhibitors, and the use of such inhibitors to raise certain plasma lipid levels, including high-density lipoprotein cholesterol, and to reduce certain other plasma lipid levels, such as LDL cholesterol and triglyceriodes and, consequently, to treat diseases that are exacerbated by low levels of HDL cholesterol and / or high levels of LDL cholesterol and triglycerides, such as atherosclerosis and cardiovascular disease in some mammals, including those human beings.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP993135 ECSP993135A (en) | 1999-09-10 | 1999-09-10 | 1,2,3,4- TETRAHIDROQUINOLINAS -2-SUBSTITUTED 4- AMINO SUBSTITUTED |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP993135 ECSP993135A (en) | 1999-09-10 | 1999-09-10 | 1,2,3,4- TETRAHIDROQUINOLINAS -2-SUBSTITUTED 4- AMINO SUBSTITUTED |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP993135A true ECSP993135A (en) | 1999-10-29 |
Family
ID=42044123
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP993135 ECSP993135A (en) | 1999-09-10 | 1999-09-10 | 1,2,3,4- TETRAHIDROQUINOLINAS -2-SUBSTITUTED 4- AMINO SUBSTITUTED |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP993135A (en) |
-
1999
- 1999-09-10 EC ECSP993135 patent/ECSP993135A/en unknown
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