EE03661B1 - Vähendatud viskoossusega oftalmoloogiline kompositsioon - Google Patents
Vähendatud viskoossusega oftalmoloogiline kompositsioonInfo
- Publication number
- EE03661B1 EE03661B1 EE9600120A EE9600120A EE03661B1 EE 03661 B1 EE03661 B1 EE 03661B1 EE 9600120 A EE9600120 A EE 9600120A EE 9600120 A EE9600120 A EE 9600120A EE 03661 B1 EE03661 B1 EE 03661B1
- Authority
- EE
- Estonia
- Prior art keywords
- amount
- pct
- weight
- viscosity
- composition
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 150000003839 salts Chemical class 0.000 abstract 3
- 229920000642 polymer Polymers 0.000 abstract 2
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000000872 buffer Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229920001477 hydrophilic polymer Polymers 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
- 239000000080 wetting agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9401108A SE9401108D0 (sv) | 1994-03-31 | 1994-03-31 | Ophthalmic composition I |
| PCT/FI1995/000166 WO1995026711A1 (en) | 1994-03-31 | 1995-03-29 | Ophthalmic composition with decreased viscosity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EE9600120A EE9600120A (et) | 1997-04-15 |
| EE03661B1 true EE03661B1 (et) | 2002-04-15 |
Family
ID=20393511
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EE9600120A EE03661B1 (et) | 1994-03-31 | 1995-03-29 | Vähendatud viskoossusega oftalmoloogiline kompositsioon |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US5710182A (pl) |
| EP (1) | EP0752847B1 (pl) |
| JP (1) | JPH10503470A (pl) |
| KR (1) | KR100365914B1 (pl) |
| CN (1) | CN1112918C (pl) |
| AT (1) | ATE202921T1 (pl) |
| AU (1) | AU694497B2 (pl) |
| BG (1) | BG63145B1 (pl) |
| BR (1) | BR9507438A (pl) |
| CA (1) | CA2186734A1 (pl) |
| CZ (1) | CZ290987B6 (pl) |
| DE (2) | DE752847T1 (pl) |
| DK (1) | DK0752847T3 (pl) |
| EE (1) | EE03661B1 (pl) |
| ES (1) | ES2161874T3 (pl) |
| GR (1) | GR3036763T3 (pl) |
| HU (1) | HU223071B1 (pl) |
| MX (1) | MX9603918A (pl) |
| NO (1) | NO314434B1 (pl) |
| PL (1) | PL179433B1 (pl) |
| PT (1) | PT752847E (pl) |
| RO (1) | RO115409B1 (pl) |
| RU (1) | RU2139016C1 (pl) |
| SE (1) | SE9401108D0 (pl) |
| SK (1) | SK280492B6 (pl) |
| WO (1) | WO1995026711A1 (pl) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9718568D0 (en) | 1997-09-03 | 1997-11-05 | Chauvin Pharmaceuticals Limite | Compositions |
| AU4808000A (en) | 1999-04-28 | 2000-11-10 | Situs Corporation | Drug delivery system |
| KR100366439B1 (ko) * | 2000-02-21 | 2003-01-09 | 주식회사 대웅 | 상피세포 성장인자를 유효성분으로 하는 안정한 약제학적조성물 |
| US6852688B2 (en) | 2000-03-10 | 2005-02-08 | University Of Florida | Compositions for treating diabetic retinopathy and methods of using same |
| RU2191013C2 (ru) * | 2000-10-04 | 2002-10-20 | Федеральное унитарное предприятие "Московский эндокринный завод" | Антиглаукоматозное средство |
| PT1484054E (pt) * | 2002-02-22 | 2012-11-28 | Santen Pharmaceutical Co Ltd | Sistema de administração de fármaco para administração subconjuntival de partículas finas |
| MXPA04008171A (es) * | 2002-02-22 | 2004-11-26 | Pharmacia Corp | Formulacion oftalmica con sistema de goma. |
| CN100453066C (zh) * | 2002-12-04 | 2009-01-21 | 参天制药株式会社 | 利用结膜下储存库的药物释放系统 |
| JP2004196787A (ja) * | 2002-12-04 | 2004-07-15 | Santen Pharmaceut Co Ltd | 結膜下デポによるドラッグデリバリーシステム |
| US7947295B2 (en) * | 2003-06-13 | 2011-05-24 | Alcon, Inc. | Ophthalmic compositions containing a synergistic combination of two polymers |
| CA2839847C (en) * | 2003-06-13 | 2016-03-15 | Masood A. Chowhan | Ophthalmic compositions containing a synergistic combination of two polymers |
| WO2005018608A1 (ja) * | 2003-08-20 | 2005-03-03 | Santen Pharmaceutical Co., Ltd. | 微粒子テノン嚢下投与ドラッグデリバリーシステム |
| RU2278656C1 (ru) * | 2004-11-29 | 2006-06-27 | Уфимский научно-исследовательский институт глазных болезней | Вискоэластик для защиты внутриглазных тканей глаза |
| TWI367098B (en) * | 2004-12-23 | 2012-07-01 | Kowa Co | Treating agent for glaucoma |
| US7862552B2 (en) | 2005-05-09 | 2011-01-04 | Boston Scientific Scimed, Inc. | Medical devices for treating urological and uterine conditions |
| DE102005035986B4 (de) * | 2005-07-28 | 2009-10-15 | Bausch & Lomb Incorporated | Steriles tropfbares mehrphasiges emulgatorfreies ophthalmisches Präparat |
| RU2340327C1 (ru) * | 2007-05-03 | 2008-12-10 | Лев Давидович Раснецов | Офтальмологический гель и способ его приготовления |
| US20110190323A1 (en) * | 2008-08-28 | 2011-08-04 | President And Fellows Of Harvard College | Cortistatin analogues and syntheses thereof |
| EP2383286A1 (en) | 2010-04-30 | 2011-11-02 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and compositions for treatment of retinal degenerative diseases |
| TW201309343A (zh) * | 2011-02-10 | 2013-03-01 | 參天製藥股份有限公司 | 經改善親水性藥物之藥物移行性之水性組成物 |
| WO2013124477A1 (en) | 2012-02-24 | 2013-08-29 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and compositions for treatment of retinal degenerative diseases |
| AU2014369834B2 (en) | 2013-12-24 | 2018-12-20 | President And Fellows Of Harvard College | Cortistatin analogues and syntheses and uses thereof |
| WO2016182932A1 (en) | 2015-05-08 | 2016-11-17 | President And Fellows Of Harvard College | Cortistatin analogues, syntheses, and uses thereof |
| EP3302426A4 (en) | 2015-05-29 | 2018-12-05 | Sydnexis, Inc. | D2o stabilized pharmaceutical formulations |
| EP3316889A4 (en) | 2015-07-01 | 2018-11-14 | President and Fellows of Harvard College | Cortistatin analogues and syntheses and uses thereof |
| AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
| WO2017035408A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Compounds for treatment of immune and inflammatory disorders |
| CN109475756A (zh) | 2016-02-17 | 2019-03-15 | 儿童医疗中心有限公司 | Ffa1(gpr40)作为神经血管生成疾病或病症的治疗标靶 |
| CN109790143A (zh) | 2016-05-10 | 2019-05-21 | C4医药公司 | 用于靶蛋白降解的胺连接的c3-戊二酰亚胺降解决定子体 |
| SG11201811491YA (en) | 2016-06-27 | 2019-01-30 | Achillion Pharmaceuticals Inc | Quinazoline and indole compounds to treat medical disorders |
| WO2018033854A1 (en) | 2016-08-15 | 2018-02-22 | Santen Pharmaceutical Co., Ltd. | Ophthalmic composition and a method for treating ocular hypertension and glaucoma |
| PT3500255T (pt) | 2016-08-19 | 2023-01-10 | Orasis Pharmaceuticals Ltd | Composições farmacêuticas oftálmicas e utilizações relacionadas com estas |
| CN110603252A (zh) | 2017-03-01 | 2019-12-20 | 艾其林医药公司 | 用于治疗医学障碍的芳基、杂芳基和杂环药物化合物 |
| US10251875B2 (en) * | 2017-05-11 | 2019-04-09 | Nevakar Inc. | Atropine pharmaceutical compositions |
| CN110769822A (zh) | 2017-06-20 | 2020-02-07 | C4医药公司 | 用于蛋白降解的n/o-连接的降解决定子和降解决定子体 |
| EP3773576A4 (en) | 2018-03-26 | 2021-12-29 | C4 Therapeutics, Inc. | Cereblon binders for the degradation of ikaros |
| US20230022157A1 (en) | 2018-08-20 | 2023-01-26 | Achillion Pharmaceuticals, Inc. | Pharmaceutical compounds for the treatment of complement factor d medical disorders |
| JP7443375B2 (ja) | 2018-09-06 | 2024-03-05 | アキリオン ファーマシューティカルズ, インコーポレーテッド | 医学的障害の治療のための大環状化合物 |
| EP3866773B1 (en) | 2018-10-16 | 2024-08-28 | Georgia State University Research Foundation, Inc. | Carbon monoxide prodrugs for the treatment of medical disorders |
| GB201904125D0 (en) | 2019-03-26 | 2019-05-08 | Ge Healthcare Bio Sciences Ab | Method for sanitization of a chromatography column |
| WO2020210630A1 (en) | 2019-04-12 | 2020-10-15 | C4 Therapeutics, Inc. | Tricyclic degraders of ikaros and aiolos |
| CN115362162A (zh) | 2020-02-20 | 2022-11-18 | 艾其林医药公司 | 用于治疗补体因子d介导的障碍的杂芳基化合物 |
| TW202146412A (zh) | 2020-03-05 | 2021-12-16 | 美商C4醫藥公司 | 用於標靶降解brd9之化合物 |
| CN116437913A (zh) | 2020-09-23 | 2023-07-14 | 艾其林医药公司 | 用于治疗补体介导的病症的药物化合物 |
| US20240139166A1 (en) * | 2021-02-04 | 2024-05-02 | Sydnexis, Inc. | Ophthalmic compositions for presbyopia |
| EP4088713A1 (en) | 2021-05-10 | 2022-11-16 | Warszawskie Zaklady Farmaceutyczne Polfa S.A. | Ophthalmic pharmaceutical composition comprising atropine |
| EP4088714A1 (en) | 2021-05-10 | 2022-11-16 | Warszawskie Zaklady Farmaceutyczne Polfa S.A. | Ophthalmic pharmaceutical composition comprising atropine |
| CN113786380A (zh) * | 2021-09-18 | 2021-12-14 | 华北制药股份有限公司 | 一种硝酸毛果芸香碱眼用凝胶及其制备方法 |
| WO2025160409A1 (en) | 2024-01-26 | 2025-07-31 | Flagship Pioneering Innovations V, Inc. | Viral vectors for modulating vegf function |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6056684B2 (ja) * | 1977-11-07 | 1985-12-11 | 東興薬品工業株式会社 | 点眼剤 |
| RU2000790C1 (ru) * | 1987-07-15 | 1993-10-15 | Уфимский научно-исследовательский институт глазных болезней | Глазна мазь |
| US5252318A (en) * | 1990-06-15 | 1993-10-12 | Allergan, Inc. | Reversible gelation compositions and methods of use |
| FR2678832B1 (fr) * | 1991-07-10 | 1995-03-17 | Europhta Sa Laboratoire | Nouvelles compositions ophtalmiques a resorption amelioree et leurs procedes de preparation. |
| RU2056821C1 (ru) * | 1993-02-26 | 1996-03-27 | Межотраслевой научно-технический комплекс "Микрохирургия глаза" | Глазные капли "кератоник" |
-
1994
- 1994-03-31 SE SE9401108A patent/SE9401108D0/xx unknown
-
1995
- 1995-03-29 DE DE0752847T patent/DE752847T1/de active Pending
- 1995-03-29 BR BR9507438A patent/BR9507438A/pt not_active IP Right Cessation
- 1995-03-29 SK SK1239-96A patent/SK280492B6/sk not_active IP Right Cessation
- 1995-03-29 CA CA002186734A patent/CA2186734A1/en not_active Abandoned
- 1995-03-29 DE DE69521686T patent/DE69521686T2/de not_active Expired - Lifetime
- 1995-03-29 PT PT95914362T patent/PT752847E/pt unknown
- 1995-03-29 HU HU9602691A patent/HU223071B1/hu active IP Right Grant
- 1995-03-29 CN CN95192185A patent/CN1112918C/zh not_active Expired - Fee Related
- 1995-03-29 RU RU96119953A patent/RU2139016C1/ru active
- 1995-03-29 ES ES95914362T patent/ES2161874T3/es not_active Expired - Lifetime
- 1995-03-29 US US08/535,037 patent/US5710182A/en not_active Expired - Lifetime
- 1995-03-29 AU AU21389/95A patent/AU694497B2/en not_active Ceased
- 1995-03-29 WO PCT/FI1995/000166 patent/WO1995026711A1/en not_active Ceased
- 1995-03-29 CZ CZ19962865A patent/CZ290987B6/cs not_active IP Right Cessation
- 1995-03-29 PL PL95316584A patent/PL179433B1/pl unknown
- 1995-03-29 DK DK95914362T patent/DK0752847T3/da active
- 1995-03-29 EP EP95914362A patent/EP0752847B1/en not_active Expired - Lifetime
- 1995-03-29 AT AT95914362T patent/ATE202921T1/de active
- 1995-03-29 EE EE9600120A patent/EE03661B1/xx unknown
- 1995-03-29 JP JP7525423A patent/JPH10503470A/ja not_active Ceased
- 1995-03-29 KR KR1019960705391A patent/KR100365914B1/ko not_active Expired - Fee Related
- 1995-03-29 MX MX9603918A patent/MX9603918A/es unknown
- 1995-03-29 RO RO96-01877A patent/RO115409B1/ro unknown
-
1996
- 1996-09-27 NO NO19964070A patent/NO314434B1/no not_active IP Right Cessation
- 1996-10-16 BG BG100915A patent/BG63145B1/bg unknown
-
2001
- 2001-09-28 GR GR20010401621T patent/GR3036763T3/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB4A | Valid patent at the end of a year |
Effective date: 20021231 |
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| KB4A | Valid patent at the end of a year |
Effective date: 20031231 |
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| KB4A | Valid patent at the end of a year |
Effective date: 20041231 |
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| KB4A | Valid patent at the end of a year |
Effective date: 20051231 |
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| KB4A | Valid patent at the end of a year |
Effective date: 20061231 |
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| KB4A | Valid patent at the end of a year |
Effective date: 20071231 |
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| KB4A | Valid patent at the end of a year |
Effective date: 20081231 |
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| KB4A | Valid patent at the end of a year |
Effective date: 20091231 |
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| KB4A | Valid patent at the end of a year |
Effective date: 20101231 |