EE04438B1 - Bensodioksaani, bensofuraani või bensopüraani derivaadid, nende valmistamismeetod ja kasutamine ning farmatseutiline kompositsioon ja selle valmistamismeetod - Google Patents

Bensodioksaani, bensofuraani või bensopüraani derivaadid, nende valmistamismeetod ja kasutamine ning farmatseutiline kompositsioon ja selle valmistamismeetod

Info

Publication number
EE04438B1
EE04438B1 EEP200000328A EEP200000328A EE04438B1 EE 04438 B1 EE04438 B1 EE 04438B1 EE P200000328 A EEP200000328 A EE P200000328A EE P200000328 A EEP200000328 A EE P200000328A EE 04438 B1 EE04438 B1 EE 04438B1
Authority
EE
Estonia
Prior art keywords
benzodioxane
benzofuran
preparation
pharmaceutical composition
benzopyran derivatives
Prior art date
Application number
EEP200000328A
Other languages
English (en)
Inventor
Tom Bert Paul Wigerinck Piet
Gaston Verschueren Wim
Francis Josephine Schroven Marc
Frans Leopold De Bruyn Marcel
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of EE200000328A publication Critical patent/EE200000328A/et
Publication of EE04438B1 publication Critical patent/EE04438B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
EEP200000328A 1997-12-05 1998-11-27 Bensodioksaani, bensofuraani või bensopüraani derivaadid, nende valmistamismeetod ja kasutamine ning farmatseutiline kompositsioon ja selle valmistamismeetod EE04438B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97203808 1997-12-05
PCT/EP1998/007771 WO1999029687A1 (en) 1997-12-05 1998-11-27 (benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties

Publications (2)

Publication Number Publication Date
EE200000328A EE200000328A (et) 2001-08-15
EE04438B1 true EE04438B1 (et) 2005-02-15

Family

ID=8229014

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000328A EE04438B1 (et) 1997-12-05 1998-11-27 Bensodioksaani, bensofuraani või bensopüraani derivaadid, nende valmistamismeetod ja kasutamine ning farmatseutiline kompositsioon ja selle valmistamismeetod

Country Status (31)

Country Link
US (4) US6133277A (et)
EP (1) EP1036073B8 (et)
JP (1) JP2001525407A (et)
KR (1) KR100591605B1 (et)
CN (1) CN1155597C (et)
AR (1) AR017195A1 (et)
AT (1) ATE334125T1 (et)
AU (1) AU748669B2 (et)
BG (1) BG64624B1 (et)
BR (1) BR9814256A (et)
CA (1) CA2311669C (et)
CO (1) CO5011114A1 (et)
CZ (1) CZ297895B6 (et)
DE (1) DE69835372T2 (et)
EA (1) EA003365B1 (et)
EE (1) EE04438B1 (et)
ES (1) ES2270541T3 (et)
HR (1) HRP20000340B1 (et)
HU (1) HU224813B1 (et)
ID (1) ID24616A (et)
IL (1) IL136529A (et)
MY (1) MY124586A (et)
NO (1) NO320727B1 (et)
NZ (1) NZ503603A (et)
PL (1) PL191144B1 (et)
SK (1) SK286268B6 (et)
TR (1) TR200001542T2 (et)
TW (1) TW577886B (et)
UA (1) UA70308C2 (et)
WO (1) WO1999029687A1 (et)
ZA (1) ZA9811081B (et)

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US6133277A (en) 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties
EE04780B1 (et) * 1999-06-02 2007-02-15 Janssen Pharmaceutica N.V. Aminoalküül-asendatud bensodioksaani, bensofuraani või bensopüraani derivaadid, nende valmistamismeetod, farmatseutiline kompositsioon ja selle valmistamismeetod
SK286159B6 (sk) * 1999-06-02 2008-04-07 Janssen Pharmaceutica N. V. Benzodioxánový, benzofuránový alebo benzopyránovýderivát, spôsob jeho prípravy, tento derivát na použitie ako liečivo, farmaceutická kompozícia obsahujúca tento derivát a spôsob jej prípravy
JO2352B1 (en) 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus
JO2654B1 (en) * 2000-09-04 2012-06-17 شركة جانسين فارماسوتيكا ان. في Multiple aryl caroxa amides are useful as lipid - lowering agents
JO2409B1 (en) 2000-11-21 2007-06-17 شركة جانسين فارماسوتيكا ان. في Second-phenyl carboxy amides are useful as lipid-lowering agents
US6688079B2 (en) 2001-04-18 2004-02-10 Kraft Foods Holdings, Inc. Method for manufacturing flexible packages having slide closures
JPWO2003040382A1 (ja) * 2001-11-09 2005-03-03 株式会社カネカ 光学活性クロマン誘導体の製造法および中間体
ES2199086B1 (es) 2002-07-31 2005-06-01 Cepa Schwarz Pharma Sl Nuevos derivados de cicloalcanodionas, procedimiento para su preparacion y sus aplicaciones farmacologicas.
US7071821B2 (en) * 2003-05-14 2006-07-04 Bellsouth Intellectual Property Corporation Method and system for alerting a person to a situation
ITTO20030140U1 (it) * 2003-09-16 2005-03-17 Interfila Srl Matita cosmetica
WO2005033093A1 (en) 2003-09-19 2005-04-14 Galileo Pharmaceuticals, Inc. 7,8-bicycloalkyl-chroman derivatives
BRPI0416206A (pt) 2003-11-20 2006-12-26 Janssen Pharmaceutica Nv 2-quinolinonas e 2-quinoxalinonas substituìdas por 6-alquenila e 6-fenilalquila como inibidores de polimerase de poli(adp-ribose)
CA2546002C (en) 2003-11-20 2012-09-18 Janssen Pharmaceutica N.V. 7-phenylalkyl substituted 2-quinolinones and 2-quinoxalinones as poly(adp-ribose) polymerase inhibitors
ES2238015B1 (es) * 2004-01-30 2006-11-01 Cepa Schwarz Pharma, S.L. Derivados de cicloalcanodionas con actividad neuroprotectora.
EA011552B1 (ru) 2004-06-30 2009-04-28 Янссен Фармацевтика Н.В. Производные хиназолиндиона в качестве ингибиторов parp
SG154433A1 (en) 2004-06-30 2009-08-28 Janssen Pharmaceutica Nv Phthalazine derivatives as parp inhibitors
ATE540936T1 (de) 2004-06-30 2012-01-15 Janssen Pharmaceutica Nv Substituierte 2-alkyl-chinazolinonderivate als parp-hemmer
RU2391350C2 (ru) * 2004-07-02 2010-06-10 Базелль Полиолефине Гмбх Способ рацемоселективного синтеза анса-металлоценов
DE102004032277A1 (de) * 2004-07-02 2006-01-19 Basell Polyolefine Gmbh Verfahren zur racemoselektiven Synthese von ansa-Metallocenen
JP2008530229A (ja) 2005-02-17 2008-08-07 ワイス シクロアルキル縮合インドール、ベンゾチオフェン、ベンゾフランおよびインデン誘導体
WO2006116165A1 (en) * 2005-04-22 2006-11-02 Wyeth Chromane and chromene derivatives and uses thereof
WO2008015538A2 (en) * 2006-07-31 2008-02-07 Schwarz Pharma S.L. Use of diaza- and thiaza-cycloalkanediones for preventing and/or treating pain and /or migraine
US20080033050A1 (en) 2006-08-04 2008-02-07 Richards Patricia Allison Tewe Method of treating thermoregulatory disfunction with paroxetine
US8503431B2 (en) * 2006-08-25 2013-08-06 Wireless Wonders Ltd. Mobile phone related indirect communication system and method
US8299256B2 (en) 2007-03-08 2012-10-30 Janssen Pharmaceutica Nv Quinolinone derivatives as PARP and TANK inhibitors
JP5017703B2 (ja) * 2007-05-16 2012-09-05 住友ゴム工業株式会社 ビードエイペックスおよびタイヤ
US8404713B2 (en) 2007-10-26 2013-03-26 Janssen Pharmaceutica Nv Quinolinone derivatives as PARP inhibitors
ES2367760T3 (es) 2008-03-27 2011-11-08 Janssen Pharmaceutica, N.V. Derivados de quinazolinona como inhibidores de la polimerización de la tubulina.
CN101981013B (zh) 2008-03-27 2013-05-29 詹森药业有限公司 作为parp和微管蛋白聚合抑制剂的四氢菲啶酮和四氢环戊二烯并喹啉酮
PL2817299T3 (pl) 2012-02-24 2019-12-31 Lupin Limited Podstawione związki chromanowe jako modulatory receptorów wapniowych
DE102012206062B4 (de) 2012-04-13 2019-09-12 Adidas Ag Schuhoberteil
WO2014102592A2 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Oxime/substituted quinoxaline-type piperidine compounds and uses thereof
DE102013207163B4 (de) 2013-04-19 2022-09-22 Adidas Ag Schuhoberteil
DE102014220087B4 (de) 2014-10-02 2016-05-12 Adidas Ag Flachgestricktes Schuhoberteil für Sportschuhe
EP3397643A1 (en) 2015-12-30 2018-11-07 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Pt(IV) PRODRUGS
CN119462701A (zh) * 2024-10-11 2025-02-18 合肥工业大学 一种四吡啶草酸铜金属配合物的制备及用途

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DE2852945A1 (de) * 1978-12-07 1980-06-26 Boehringer Sohn Ingelheim Benzodioxanyl-hydroxyaethylpiperidyl- imidazolidinone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4329348A (en) * 1979-02-26 1982-05-11 Ciba-Geigy Corporation N-Oxacyclic-alkylpiperidines as psychostimulants
US4239348A (en) * 1979-11-30 1980-12-16 Hughes Aircraft Company High resolution AC silicon MOS light-valve substrate
DE3901814A1 (de) * 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
DE4140540A1 (de) * 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
SI9300097B (en) * 1992-02-27 2001-12-31 Janssen Pharmaceutica Nv (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines
DE4319038A1 (de) * 1993-06-08 1994-12-15 Bayer Ag Verwendung von teilweise bekannten substituierten Chromanen als Arzneimittel, neue Wirkstoffe und Verfahren zu ihrer Herstellung
ES2212797T3 (es) * 1993-08-19 2004-08-01 Janssen Pharmaceutica N.V. Derivados de dihidrobenzopirano vasoconstrictores.
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US6133277A (en) 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties

Also Published As

Publication number Publication date
HRP20000340A2 (en) 2001-04-30
ATE334125T1 (de) 2006-08-15
US20030149093A1 (en) 2003-08-07
IL136529A0 (en) 2001-06-14
AR017195A1 (es) 2001-08-22
WO1999029687A8 (en) 2000-04-13
KR20010031010A (ko) 2001-04-16
ID24616A (id) 2000-07-27
EE200000328A (et) 2001-08-15
UA70308C2 (uk) 2004-10-15
AU2412799A (en) 1999-06-28
NO20002074L (no) 2000-06-02
NZ503603A (en) 2001-10-26
ES2270541T3 (es) 2007-04-01
US6747045B2 (en) 2004-06-08
EP1036073B8 (en) 2006-11-15
NO320727B1 (no) 2006-01-23
HUP0004492A3 (en) 2002-04-29
CO5011114A1 (es) 2001-02-28
BG64624B1 (bg) 2005-09-30
ZA9811081B (en) 2000-06-22
EP1036073A1 (en) 2000-09-20
EP1036073B1 (en) 2006-07-26
DE69835372D1 (de) 2006-09-07
CZ297895B6 (cs) 2007-04-25
EA200000616A1 (ru) 2000-12-25
CA2311669C (en) 2010-04-27
US6133277A (en) 2000-10-17
CN1155597C (zh) 2004-06-30
JP2001525407A (ja) 2001-12-11
HU224813B1 (en) 2006-02-28
CN1280577A (zh) 2001-01-17
BR9814256A (pt) 2000-10-03
NO20002074D0 (no) 2000-04-19
MY124586A (en) 2006-06-30
KR100591605B1 (ko) 2006-06-20
US6852714B2 (en) 2005-02-08
IL136529A (en) 2003-03-12
SK8032000A3 (en) 2001-02-12
SK286268B6 (sk) 2008-06-06
WO1999029687A1 (en) 1999-06-17
CZ20002018A3 (cs) 2000-10-11
AU748669B2 (en) 2002-06-06
HRP20000340B1 (hr) 2008-12-31
DE69835372T2 (de) 2007-08-09
HUP0004492A2 (hu) 2002-03-28
US20030083365A1 (en) 2003-05-01
US6495547B1 (en) 2002-12-17
TR200001542T2 (tr) 2001-01-22
PL341007A1 (en) 2001-03-12
EA003365B1 (ru) 2003-04-24
BG104372A (en) 2000-12-29
PL191144B1 (pl) 2006-03-31
HK1028400A1 (en) 2001-02-16
TW577886B (en) 2004-03-01
CA2311669A1 (en) 1999-06-17

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