EE04580B1 - Mikroorganismi tüvi Lactobacillus fermentum ME-3 kui antimikroobne ja antioksüdantne probiootikum - Google Patents

Mikroorganismi tüvi Lactobacillus fermentum ME-3 kui antimikroobne ja antioksüdantne probiootikum

Info

Publication number: EE04580B1
Authority: EE; Estonia
Prior art keywords: strain; micro; probiotic; organism; oxidative
Prior art date: 2001-06-29

Application number

EEP200100356A

Other languages

English (en)

Inventor

Mikelsaar Marika

Zilmer Mihkel

Kullisaar Tiiu

Annuk Heidi

Songisepp Epp

Original Assignee

Tartu �likool

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-06-29

Filing date

2001-06-29

Publication date

2006-02-15

2001-06-29 Application filed by Tartu �likool filed Critical Tartu �likool

2001-06-29 Priority to EEP200100356A priority Critical patent/EE04580B1/et

2002-06-21 Priority to PCT/EE2002/000006 priority patent/WO2003002131A1/en

2002-06-21 Priority to US10/481,713 priority patent/US7244424B2/en

2002-06-21 Priority to DE60238482T priority patent/DE60238482D1/de

2002-06-21 Priority to ES02742853T priority patent/ES2356119T3/es

2002-06-21 Priority to AT02742853T priority patent/ATE489959T1/de

2002-06-21 Priority to EP02742853A priority patent/EP1401457B1/en

2002-06-21 Priority to RU2003137810/13A priority patent/RU2284354C2/ru

2002-06-21 Priority to DK02742853.1T priority patent/DK1401457T3/da

2003-02-17 Publication of EE200100356A publication Critical patent/EE200100356A/et

2006-02-15 Publication of EE04580B1 publication Critical patent/EE04580B1/et

Links

244000005700 microbiome Species 0.000 title abstract 4
230000000845 anti-microbial effect Effects 0.000 title abstract 3
230000003078 antioxidant effect Effects 0.000 title abstract 3
239000006041 probiotic Substances 0.000 title abstract 3
230000000529 probiotic effect Effects 0.000 title abstract 3
235000018291 probiotics Nutrition 0.000 title abstract 3
241000186840 Lactobacillus fermentum Species 0.000 title abstract 2
239000004599 antimicrobial Substances 0.000 title abstract 2
229940012969 lactobacillus fermentum Drugs 0.000 title abstract 2
239000003963 antioxidant agent Substances 0.000 title 1
RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 abstract 2
208000017667 Chronic Disease Diseases 0.000 abstract 1
241000588724 Escherichia coli Species 0.000 abstract 1
108010024636 Glutathione Proteins 0.000 abstract 1
241000590002 Helicobacter pylori Species 0.000 abstract 1
241000293869 Salmonella enterica subsp. enterica serovar Typhimurium Species 0.000 abstract 1
241000607760 Shigella sonnei Species 0.000 abstract 1
241000191967 Staphylococcus aureus Species 0.000 abstract 1
102000019197 Superoxide Dismutase Human genes 0.000 abstract 1
108010012715 Superoxide dismutase Proteins 0.000 abstract 1
239000008280 blood Substances 0.000 abstract 1
210000004369 blood Anatomy 0.000 abstract 1
239000002775 capsule Substances 0.000 abstract 1
235000013351 cheese Nutrition 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
235000013376 functional food Nutrition 0.000 abstract 1
229960003180 glutathione Drugs 0.000 abstract 1
229940037467 helicobacter pylori Drugs 0.000 abstract 1
230000000968 intestinal effect Effects 0.000 abstract 1
239000006166 lysate Substances 0.000 abstract 1
230000036542 oxidative stress Effects 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1
230000002035 prolonged effect Effects 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
229940115939 shigella sonnei Drugs 0.000 abstract 1
231100000331 toxic Toxicity 0.000 abstract 1
230000002588 toxic effect Effects 0.000 abstract 1
238000011282 treatment Methods 0.000 abstract 1
235000013618 yogurt Nutrition 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Mycology (AREA)
Microbiology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Molecular Biology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)
Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Medicinal Preparation (AREA)
Fodder In General (AREA)
Anti-Oxidant Or Stabilizer Compositions (AREA)

EEP200100356A 2001-06-29 2001-06-29 Mikroorganismi tüvi Lactobacillus fermentum ME-3 kui antimikroobne ja antioksüdantne probiootikum EE04580B1 (et)

Priority Applications (9)

Application Number	Priority Date	Filing Date	Title
EEP200100356A EE04580B1 (et)	2001-06-29	2001-06-29	Mikroorganismi tüvi Lactobacillus fermentum ME-3 kui antimikroobne ja antioksüdantne probiootikum
PCT/EE2002/000006 WO2003002131A1 (en)	2001-06-29	2002-06-21	Strain of micro-organism lactobacillus fermentum me-3 as novel anti-microbial and antioxidative probiotic
US10/481,713 US7244424B2 (en)	2001-06-29	2002-06-21	Strain of micro-organism Lactobacillus fermentum ME-3 as novel anti-microbiol and anti-oxidative probiotic
DE60238482T DE60238482D1 (de)	2001-06-29	2002-06-21	Mikroorganismus stamm lactobacillus fermentum me-3 als neues antioxidatives probiotisches mittel
ES02742853T ES2356119T3 (es)	2001-06-29	2002-06-21	Cepa del microorganismo lactobacillus fermentum me-3 como nuevo probiótico antioxidante.
AT02742853T ATE489959T1 (de)	2001-06-29	2002-06-21	Mikroorganismus stamm lactobacillus fermentum me- 3 als neues antioxidatives probiotisches mittel
EP02742853A EP1401457B1 (en)	2001-06-29	2002-06-21	Strain of micro-organism lactobacillus fermentum me-3 as novel antioxidative probiotic
RU2003137810/13A RU2284354C2 (ru)	2001-06-29	2002-06-21	Пробиотик
DK02742853.1T DK1401457T3 (da)	2001-06-29	2002-06-21	Stamme af mikroorganismen lactobacillus fermentum ME-3 som nyt antioxidativt probiotika

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EEP200100356A EE04580B1 (et)	2001-06-29	2001-06-29	Mikroorganismi tüvi Lactobacillus fermentum ME-3 kui antimikroobne ja antioksüdantne probiootikum

Publications (2)

Publication Number	Publication Date
EE200100356A EE200100356A (et)	2003-02-17
EE04580B1 true EE04580B1 (et)	2006-02-15

Family

ID=8161768

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200100356A EE04580B1 (et)	2001-06-29	2001-06-29	Mikroorganismi tüvi Lactobacillus fermentum ME-3 kui antimikroobne ja antioksüdantne probiootikum

Country Status (9)

Country	Link
US (1)	US7244424B2 (et)
EP (1)	EP1401457B1 (et)
AT (1)	ATE489959T1 (et)
DE (1)	DE60238482D1 (et)
DK (1)	DK1401457T3 (et)
EE (1)	EE04580B1 (et)
ES (1)	ES2356119T3 (et)
RU (1)	RU2284354C2 (et)
WO (1)	WO2003002131A1 (et)

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US20040170617A1 (en) *	2000-06-05	2004-09-02	Finegold Sydney M.	Method of treating diseases associated with abnormal gastrointestinal flora
EP1608737A1 (en) *	2003-04-02	2005-12-28	Axcan Pharma S.A	Lactobacillus fermentum strain and uses thereof
DE102005062731A1 (de) *	2005-12-22	2007-06-28	Organobalance Gmbh	Neue Lactobacillus Stämme und deren Verwendung
TWI346554B (en)	2008-04-30	2011-08-11	Genmont Biotech Inc	Lactobacillus isolates having anti-inflammatory activities and uses of the same
RU2412239C2 (ru) *	2008-08-15	2011-02-20	Учреждение Российской Академии медицинских наук Научно-исследовательский институт экспериментальной медицины Северо-Западного отделения РАМН /НИИЭМ СЗО РАМН/	ШТАММ Lactobacillus fermentum Z, ИСПОЛЬЗУЕМЫЙ ДЛЯ ПРОИЗВОДСТВА ПРОБИОТИЧЕСКИХ МОЛОЧНОКИСЛЫХ ПРОДУКТОВ
RU2391395C1 (ru) *	2008-11-19	2010-06-10	Галина Геннадиевна Алехина	ШТАММ Lactobacillus fermentum TS3-06, ИСПОЛЬЗУЕМЫЙ ДЛЯ ИЗГОТОВЛЕНИЯ БАКТЕРИАЛЬНЫХ ПРЕПАРАТОВ И ПРОИЗВОДСТВА ЖИДКОЙ МОЛОЧНОКИСЛОЙ ЗАКВАСКИ В КАЧЕСТВЕ ПРОДУКТА ПИТАНИЯ ЛЕЧЕБНО-ПРОФИЛАКТИЧЕСКОГО НАЗНАЧЕНИЯ
JP2012531189A (ja) *	2009-06-30	2012-12-10	セーホーエル．ハンセンアクティーゼルスカブ	発酵乳製品の生産のための方法
CN102858948B (zh)	2010-01-08	2015-11-25	热尔韦·达诺尼公司	具有抗氧化作用的乳酸杆菌
ES2543738T3 (es)	2010-01-08	2015-08-21	Compagnie Gervais Danone	Método para seleccionar bacterias con acción antioxidante
US9707207B2 (en)	2010-05-26	2017-07-18	The United States Of America As Represented By The Department Of Veterans Affairs	Method for diagnosing, preventing, and treating neurological diseases
CN103648511B (zh) *	2011-06-08	2018-12-07	诺沃奇梅兹有限公司	喷雾干燥的乳杆菌属菌株/细胞及其对抗幽门螺杆菌的用途
JP6240610B2 (ja) *	2011-10-27	2017-11-29	サリックスファーマシューティカルズ，インコーポレイテッド	電解質下剤
WO2013062034A1 (ja) *	2011-10-28	2013-05-02	株式会社明治	ナチュラルチーズおよびその製造方法
GB201223370D0 (en)	2012-12-24	2013-02-06	Univ Tartu	Method of treatment using lactobacillus fermentum ME-3
US20160279180A1 (en) *	2013-08-23	2016-09-29	Consejo Superior de Investigaciones Científicas ( CSIC)	Probiotic Strain of Lactobacillus Reuteri Exhibiting Anti-Helicobacter Activity, a Probiotic or Biotherapeutic Product Comprising Said Strain, and the Use Thereof
RS57471B1 (sr) *	2015-12-17	2018-09-28	Institut Za Molekularnu Genetiku I Geneticko Inzenjerstvo Univerzitet U Beogradu	Nova probiotička starter kultura za humanu i animalnu primenu
CN106967630B (zh) *	2016-12-01	2019-12-10	广东省微生物研究所（广东省微生物分析检测中心）	一种发酵乳杆菌及其应用
RU2705250C2 (ru) *	2018-02-05	2019-11-06	Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан"	Штамм Lactobacillus fermentum U-21, продуцирующий комплекс биологически активных веществ, осуществляющих нейтрализацию супероксид-аниона, индуцируемого химическими агентами
US20220151267A1 (en) *	2019-04-16	2022-05-19	Locus Ip Company, Llc	Microbe-Based Emulsifying Food Additives
RU2757118C2 (ru) *	2019-12-11	2021-10-11	Общество с ограниченной ответственностью "Фармабиотики"	Применение клеток штамма Lactobacillus fermentum U-21 для предотвращения патологических изменений в тканях, вызванных оксидативным стрессом
KR102424594B1 (ko) *	2020-11-30	2022-07-25	파이토지노믹스 주식회사	항염 활성 및 유해 미생물에 대한 항균 활성을 가지는 락토바실러스 퍼멘텀 okbl-l.fe 1 균주 및 이의 용도
CN116574630B (zh) *	2023-01-31	2024-02-20	江苏省农业科学院	具有抑菌和抗氧化活性的乳杆菌、适用于秸秆青贮的复合微生物菌剂及其应用
CN116590175A (zh) *	2023-04-12	2023-08-15	吉林省中科特殊食品创新研究院有限公司	一种发酵乳杆菌elf041及其应用
CN119193375A (zh) *	2024-09-19	2024-12-27	扬州大学	植物乳杆菌Grx403及其在制备发酵酶解脱脂乳中的应用

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IT1227154B (it) *	1988-08-05	1991-03-19	A Tosi Farmaceutici S R L Nova	Composizioni farmaceutiche per uso ginecologico a base di lattobacilli
US6180100B1 (en) *	1994-09-30	2001-01-30	Urex Biotech., Inc.	Lactobacillus compositions and methods for treating urinary tract infections
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KR100211529B1 (ko)	1997-04-28	1999-08-02	박원훈	유해 미생물 억제 활성을 갖는 신규 내산성 락토바실러스 속 미생물 및 이를 함유하는 가축용 생균활성제
IT1299070B1 (it) *	1998-04-10	2000-02-07	Proge Farm Srl	Ceppi di lattobacilli capaci di inibire e/o avere azione microbicida nei confronti di microorganismi patogeni e metodo di induzione e
RU2133272C1 (ru)	1998-06-11	1999-07-20	Акционерное общество открытого типа "Биомед" им.И.И.Мечникова	Штамм бактерии lactobacillus fermentum 90-ts-4(21), используемый для получения эубиотического препарата для применения в гинекологической практике
CA2354054C (en) *	1998-12-11	2011-04-12	Urex Biotech, Inc.	Oral administration of lactobacillus for the treatment and prevention of urogenital infection

2001
- 2001-06-29 EE EEP200100356A patent/EE04580B1/et unknown
2002
- 2002-06-21 DK DK02742853.1T patent/DK1401457T3/da active
- 2002-06-21 EP EP02742853A patent/EP1401457B1/en not_active Expired - Lifetime
- 2002-06-21 ES ES02742853T patent/ES2356119T3/es not_active Expired - Lifetime
- 2002-06-21 WO PCT/EE2002/000006 patent/WO2003002131A1/en not_active Ceased
- 2002-06-21 US US10/481,713 patent/US7244424B2/en not_active Expired - Fee Related
- 2002-06-21 RU RU2003137810/13A patent/RU2284354C2/ru active
- 2002-06-21 DE DE60238482T patent/DE60238482D1/de not_active Expired - Lifetime
- 2002-06-21 AT AT02742853T patent/ATE489959T1/de active

Also Published As

Publication number	Publication date
DE60238482D1 (de)	2011-01-13
EE200100356A (et)	2003-02-17
US20040151708A1 (en)	2004-08-05
EP1401457B1 (en)	2010-12-01
ES2356119T3 (es)	2011-04-05
WO2003002131B1 (en)	2003-03-06
US7244424B2 (en)	2007-07-17
DK1401457T3 (da)	2011-01-17
WO2003002131A1 (en)	2003-01-09
ATE489959T1 (de)	2010-12-15
RU2284354C2 (ru)	2006-09-27
EP1401457A1 (en)	2004-03-31
RU2003137810A (ru)	2005-05-20

Legal Events

Date	Code	Title	Description
2007-02-15	KB4A	Valid patent at the end of a year	Effective date: 20061231
2008-02-15	KB4A	Valid patent at the end of a year	Effective date: 20071231
2009-02-16	KB4A	Valid patent at the end of a year	Effective date: 20081231
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231

Publication	Publication Date	Title
EE200100356A (et)	2003-02-17	Mikroorganismi tüvi Lactobacillus fermentum ME-3 kui uudne antimikroobne ja antioksüdantne probiootikum
Piekarska-Radzik et al.	2021	Mutual influence of polyphenols and Lactobacillus spp. bacteria in food: A review
Aguilar-Galvez et al.	2014	Potential of tara (Caesalpinia spinosa) gallotannins and hydrolysates as natural antibacterial compounds
Gotteland et al.	2006	Systematic review: are probiotics useful in controlling gastric colonization by Helicobacter pylori?
Abuelsaad et al.	2013	Antimicrobial and immunomodulating activities of hesperidin and ellagic acid against diarrheic Aeromonas hydrophila in a murine model
Singh et al.	2011	Antimicrobial activity of lemongrass (Cymbopogon citratus) oil against microbes of environmental, clinical and food origin.
Joshi et al.	2014	Cronobacter sakazakii reduction by blueberry proanthocyanidins
Min et al.	2014	Antimicrobial activity of acid-hydrolyzed Citrus unshiu peel extract in milk
Ankolekar et al.	2012	Fermentation of whole apple juice using Lactobacillus acidophilus for potential dietary management of hyperglycemia, hypertension, and modulation of beneficial bacterial responses
Javed et al.	2022	Signature probiotic and pharmacological attributes of lactic acid bacteria isolated from human breast milk
Serrano et al.	2020	Antimicrobial resistance of three common molecularly identified pathogenic bacteria to Allium aqueous extracts
Viedma et al.	2008	Enhanced bactericidal effect of enterocin AS-48 in combination with high-intensity pulsed-electric field treatment against Salmonella enterica in apple juice
KR20120111091A (ko)	2012-10-10	신규한 바실러스 아밀로리퀴페시언스의 배양물 및 그의 용도
WO2019209086A1 (ko)	2019-10-31	류코노스톡 메젠테로이드 균주 및 이의 용도
Chauhan et al.	2025	Screening of lactic acid bacteria from the milk of Sahiwal cows and characterization of their probiotic potential for preventing bovine mastitis
Pleskova et al.	2026	The oral microbiota, its evolution, and aspects of support for oral health
Haghighatafshar et al.	2021	The effect of bacteriocin isolated from Lactobacillus rhamnosus on Pseudomonas aeruginosa lipopolysaccharides
Kaur et al.	2018	Dietary antioxidants and infectious diseases
Nguyen et al.	2015	Biological Activities of Tetrodotoxin‐Producing Enterococcus faecium AD1 Isolated from Puffer Fishes
Rukayadi et al.	2009	Antibacterial and sporicidal activity of macelignan isolated from nutmeg (Myristica fragrans Houtt.) against Bacillus cereus
François et al.	2013	ANTIMICROBIAL ACTIVITY OF PROBIOTIC STRAIN Lactobacillus plantarum ISOLATED FROM â€ œSHAâ€™ Aâ€ AND ASSESSMENT OF ITS VIABILITY IN LOCAL HONEY
KR20120019551A (ko)	2012-03-07	소나무로부터 항균 활성 및 항산화 활성을 가진 물질을 생산하는 방법
KR102065180B1 (ko)	2020-01-17	클로스트리디오이데스 디피실레에 항균 활성을 갖는 락토바실러스 속 WiKim0092 균주 및 이를 포함하는 조성물
KR102065181B1 (ko)	2020-01-17	클로스트리디오이데스 디피실레에 항균 활성을 갖는 락토바실러스 속 WiKim0093 균주 및 이를 포함하는 조성물
Saffari et al.	2012	Comparing the antimicrobial properties of pomegranate seed and peel extract with common antibiotics used on helicobacter pylori isolated from biopsies of patients referring to Kashan Shahid-Beheshti hospital.