EE05302B1 - 4-fluoro-N-(indaan-2-l)bensamiidi kasutamine ja protsess ravimi valmistamiseks - Google Patents

4-fluoro-N-(indaan-2-l)bensamiidi kasutamine ja protsess ravimi valmistamiseks

Info

Publication number: EE05302B1
Authority: EE; Estonia
Prior art keywords: indan; fluoro; benzamide; medicament; manufacture
Prior art date: 2001-02-13

Application number

EEP200300368A

Other languages

English (en)

Estonian (et)

Inventor

Wohlfart Paulus

Suzuki Teri

M. Dharanipragada Ramalinga

Safarova Alena

Walser Armin

Strobel Hartmut

Original Assignee

Aventis Pharma Deutschland Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-02-13

Filing date

2002-02-12

Publication date

2010-06-15

2002-02-12 Application filed by Aventis Pharma Deutschland Gmbh filed Critical Aventis Pharma Deutschland Gmbh

2003-10-15 Publication of EE200300368A publication Critical patent/EE200300368A/xx

2010-06-15 Publication of EE05302B1 publication Critical patent/EE05302B1/xx

Links

238000000034 method Methods 0.000 title abstract 3
KXDAEFPNCMNJSK-UHFFFAOYSA-N Benzamide Chemical compound NC(=O)C1=CC=CC=C1 KXDAEFPNCMNJSK-UHFFFAOYSA-N 0.000 title 2
239000003814 drug Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
241000124008 Mammalia Species 0.000 abstract 1
102000008299 Nitric Oxide Synthase Human genes 0.000 abstract 1
108010021487 Nitric Oxide Synthase Proteins 0.000 abstract 1
230000003511 endothelial effect Effects 0.000 abstract 1
BOFMSBVSYVESTM-UHFFFAOYSA-N n-(2,3-dihydro-1h-inden-2-yl)-4-fluorobenzamide Chemical compound C1=CC(F)=CC=C1C(=O)NC1CC2=CC=CC=C2C1 BOFMSBVSYVESTM-UHFFFAOYSA-N 0.000 abstract 1
230000004936 stimulating effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/65—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Physical Education & Sports Medicine (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Urology & Nephrology (AREA)
Pulmonology (AREA)
Hospice & Palliative Care (AREA)
Orthopedic Medicine & Surgery (AREA)
Psychiatry (AREA)
Ophthalmology & Optometry (AREA)
Hematology (AREA)
Reproductive Health (AREA)
Rheumatology (AREA)
Gastroenterology & Hepatology (AREA)
Vascular Medicine (AREA)
Gynecology & Obstetrics (AREA)
Emergency Medicine (AREA)
Obesity (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

EEP200300368A 2001-02-13 2002-02-12 4-fluoro-N-(indaan-2-l)bensamiidi kasutamine ja protsess ravimi valmistamiseks EE05302B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01102852		2001-02-13
PCT/EP2002/001443 WO2002064146A1 (en)	2001-02-13	2002-02-12	4-fluoro-n-indan-2-yl benzamide and its use as pharmaceutical

Publications (2)

Publication Number	Publication Date
EE200300368A EE200300368A (et)	2003-10-15
EE05302B1 true EE05302B1 (et)	2010-06-15

Family

ID=8176423

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200300368A EE05302B1 (et)	2001-02-13	2002-02-12	4-fluoro-N-(indaan-2-l)bensamiidi kasutamine ja protsess ravimi valmistamiseks

Country Status (33)

Country	Link
US (3)	US6617359B2 (sr)
EP (1)	EP1361882B1 (sr)
JP (1)	JP4317689B2 (sr)
KR (1)	KR101017531B1 (sr)
CN (1)	CN100553631C (sr)
AT (1)	ATE344669T1 (sr)
AU (1)	AU2002253009B2 (sr)
BG (1)	BG66065B1 (sr)
BR (1)	BR0207178A (sr)
CA (1)	CA2437966C (sr)
CY (1)	CY1106278T1 (sr)
CZ (1)	CZ20032154A3 (sr)
DE (1)	DE60215919T2 (sr)
DK (1)	DK1361882T3 (sr)
EE (1)	EE05302B1 (sr)
ES (1)	ES2274025T3 (sr)
HR (1)	HRP20030646A2 (sr)
HU (1)	HUP0302845A3 (sr)
IL (2)	IL157208A0 (sr)
MX (1)	MXPA03006841A (sr)
MY (1)	MY135778A (sr)
NO (1)	NO333522B1 (sr)
NZ (1)	NZ527469A (sr)
PE (1)	PE20020884A1 (sr)
PL (1)	PL363452A1 (sr)
PT (1)	PT1361882E (sr)
RS (1)	RS51645B (sr)
RU (1)	RU2308946C2 (sr)
SI (1)	SI1361882T1 (sr)
SK (1)	SK286513B6 (sr)
TW (1)	TWI241190B (sr)
WO (1)	WO2002064146A1 (sr)
ZA (1)	ZA200305412B (sr)

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EP1923062A1 (en)	2006-11-16	2008-05-21	sanofi-aventis	Imidazo[2,1-b]thiazoles and their use as pharmaceuticals
KR101349187B1 (ko) *	2006-12-05	2014-01-10	(주)아모레퍼시픽	지방대사 이상질환의 치료 및 예방용 약학 조성물
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TWI243164B (en) *	2001-02-13	2005-11-11	Aventis Pharma Gmbh	Acylated indanyl amines and their use as pharmaceuticals
PE20020870A1 (es) *	2001-02-13	2002-11-18	Aventis Pharma Gmbh	6,7,8,9-tetrahidro-5h-benzocicloheptenil aminas aciladas
PE20020856A1 (es) *	2001-02-13	2002-11-11	Aventis Pharma Gmbh	1,2,3,4-tetrahidronaftil aminas aciladas
US7105513B2 (en) *	2002-08-07	2006-09-12	Sanofi-Avertis Deutschland Gmbh	Acylated, heteroaryl-condensed cycloalkenylamines and their use as pharmaceuticals
US7338956B2 (en) *	2002-08-07	2008-03-04	Sanofi-Aventis Deutschland Gmbh	Acylamino-substituted heteroaromatic compounds and their use as pharmaceuticals
US7186735B2 (en) *	2002-08-07	2007-03-06	Sanofi-Aventis Deutschland Gmbh	Acylated arylcycloalkylamines and their use as pharmaceuticals
US8309608B2 (en) *	2003-11-06	2012-11-13	Sanofi-Aventis Deutschland Gmbh	Use of eNOS transcription enhancers in the cell therapy of ischemic heart diseases

2002
- 2002-02-08 TW TW091102292A patent/TWI241190B/zh not_active IP Right Cessation
- 2002-02-11 MY MYPI20020481A patent/MY135778A/en unknown
- 2002-02-12 KR KR1020037010490A patent/KR101017531B1/ko not_active Expired - Fee Related
- 2002-02-12 NZ NZ527469A patent/NZ527469A/xx not_active IP Right Cessation
- 2002-02-12 RU RU2003127750/15A patent/RU2308946C2/ru not_active IP Right Cessation
- 2002-02-12 AU AU2002253009A patent/AU2002253009B2/en not_active Ceased
- 2002-02-12 WO PCT/EP2002/001443 patent/WO2002064146A1/en not_active Ceased
- 2002-02-12 EP EP02722066A patent/EP1361882B1/en not_active Expired - Lifetime
- 2002-02-12 HU HU0302845A patent/HUP0302845A3/hu unknown
- 2002-02-12 RS YU61703A patent/RS51645B/sr unknown
- 2002-02-12 CZ CZ20032154A patent/CZ20032154A3/cs unknown
- 2002-02-12 AT AT02722066T patent/ATE344669T1/de active
- 2002-02-12 SI SI200230443T patent/SI1361882T1/sl unknown
- 2002-02-12 IL IL15720802A patent/IL157208A0/xx unknown
- 2002-02-12 PT PT02722066T patent/PT1361882E/pt unknown
- 2002-02-12 PL PL02363452A patent/PL363452A1/xx not_active Application Discontinuation
- 2002-02-12 ES ES02722066T patent/ES2274025T3/es not_active Expired - Lifetime
- 2002-02-12 DE DE60215919T patent/DE60215919T2/de not_active Expired - Lifetime
- 2002-02-12 CN CNB028048636A patent/CN100553631C/zh not_active Expired - Fee Related
- 2002-02-12 DK DK02722066T patent/DK1361882T3/da active
- 2002-02-12 BR BR0207178-9A patent/BR0207178A/pt not_active Application Discontinuation
- 2002-02-12 SK SK1011-2003A patent/SK286513B6/sk not_active IP Right Cessation
- 2002-02-12 MX MXPA03006841A patent/MXPA03006841A/es active IP Right Grant
- 2002-02-12 HR HR20030646A patent/HRP20030646A2/hr not_active Application Discontinuation
- 2002-02-12 EE EEP200300368A patent/EE05302B1/xx not_active IP Right Cessation
- 2002-02-12 JP JP2002563939A patent/JP4317689B2/ja not_active Expired - Fee Related
- 2002-02-12 CA CA2437966A patent/CA2437966C/en not_active Expired - Fee Related
- 2002-02-13 US US10/073,330 patent/US6617359B2/en not_active Expired - Lifetime
- 2002-02-13 PE PE2002000123A patent/PE20020884A1/es not_active Application Discontinuation
2003
- 2003-07-14 ZA ZA200305412A patent/ZA200305412B/xx unknown
- 2003-07-15 BG BG107994A patent/BG66065B1/bg unknown
- 2003-07-22 US US10/623,775 patent/US6812253B2/en not_active Expired - Lifetime
- 2003-08-03 IL IL157208A patent/IL157208A/en not_active IP Right Cessation
- 2003-08-11 NO NO20033546A patent/NO333522B1/no not_active IP Right Cessation
2004
- 2004-08-18 US US10/920,395 patent/US7202278B2/en not_active Expired - Lifetime
2006
- 2006-12-06 CY CY20061101753T patent/CY1106278T1/el unknown

Also Published As

Publication number	Publication date
EP1361882B1 (en)	2006-11-08
CA2437966C (en)	2011-06-14
MXPA03006841A (es)	2003-11-13
ZA200305412B (en)	2004-09-02
US20040019114A1 (en)	2004-01-29
CN1496264A (zh)	2004-05-12
US7202278B2 (en)	2007-04-10
KR20030074809A (ko)	2003-09-19
IL157208A (en)	2009-09-22
HRP20030646A2 (en)	2005-06-30
PE20020884A1 (es)	2002-11-25
HK1062140A1 (en)	2004-10-21
IL157208A0 (en)	2004-02-19
ES2274025T3 (es)	2007-05-16
DE60215919D1 (de)	2006-12-21
US6812253B2 (en)	2004-11-02
ATE344669T1 (de)	2006-11-15
CA2437966A1 (en)	2002-08-22
BR0207178A (pt)	2004-03-30
CY1106278T1 (el)	2011-10-12
HUP0302845A2 (hu)	2003-12-29
RS51645B (sr)	2011-10-31
CZ20032154A3 (cs)	2004-05-12
DK1361882T3 (da)	2007-03-12
TWI241190B (en)	2005-10-11
RU2308946C2 (ru)	2007-10-27
BG66065B1 (bg)	2011-01-31
RS61703A (sr)	2006-12-15
NO333522B1 (no)	2013-07-01
BG107994A (bg)	2004-08-31
EP1361882A1 (en)	2003-11-19
US6617359B2 (en)	2003-09-09
US20030022939A1 (en)	2003-01-30
JP4317689B2 (ja)	2009-08-19
SK286513B6 (sk)	2008-12-05
EE200300368A (et)	2003-10-15
AU2002253009B2 (en)	2006-09-14
CN100553631C (zh)	2009-10-28
SI1361882T1 (sl)	2007-02-28
KR101017531B1 (ko)	2011-02-28
HUP0302845A3 (en)	2005-11-28
JP2004518713A (ja)	2004-06-24
NZ527469A (en)	2005-04-29
NO20033546D0 (no)	2003-08-11
PT1361882E (pt)	2007-01-31
SK10112003A3 (sk)	2004-01-08
MY135778A (en)	2008-06-30
WO2002064146A1 (en)	2002-08-22
DE60215919T2 (de)	2007-05-31
US20050054729A1 (en)	2005-03-10
RU2003127750A (ru)	2005-03-10
NO20033546L (no)	2003-09-24
PL363452A1 (en)	2004-11-15

Legal Events

Date	Code	Title	Description
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231
2013-10-15	MM4A	Lapsed by not paying the annual fees	Effective date: 20130212

Publication	Publication Date	Title
NO20033546D0 (no)	2003-08-11	4-fluor-N-indan-2-yl-benzamid og dets anvendelse som legemiddel
ATE381537T1 (de)	2008-01-15	Formanilid-derivative als beta2-adrenorezeptor- agonisten
DK1411932T3 (da)	2010-05-31	Kombinationsterapi med substituerede oxazolidinoner
SE0200979D0 (sv)	2002-03-28	New compounds
SE0100569D0 (sv)	2001-02-20	New compounds
ATE365720T1 (de)	2007-07-15	Agonisten von beta-adrenorezeptoren
BG106095A (bg)	2002-06-28	Нови лекарствени състави на базата на антихолинергично активни съединения и бета-миметици
SE0101387D0 (sv)	2001-04-20	Novel compounds
CY1107850T1 (el)	2013-06-19	Παραγωγα θειαδιαζολυλοπιπεραζiνης mε χρησιμοτητα στην αποτροπη ή στην αγωγη εναντι tου αλγους
SE0301882D0 (sv)	2003-06-25	New use I
BRPI0108395B8 (pt)	2021-05-25	derivados de pirrolopirimidinona, processos de preparação e uso
SE0301886D0 (sv)	2003-06-25	New use V
EP1543158A4 (en)	2007-06-06	REGULATED APTAMER THERAPEUTICS
DE60220055D1 (de)	2007-06-21	4-(4-methoxybenzyl)-n'-(5-nitro-1,3-thiazol-2-yl)harnstoff und dessen verwendung bei der behandlung von mit glycogensynthasekinase-3 (gsk3) assoziierten leiden
PT1030667E (pt)	2005-06-30	Utilizacao de mirtazapina para o fabrico de um medicamento para o tratamento de apenas do sono
HRP20120344T1 (hr)	2012-05-31	N-(2-hidroksietil)-n-metil-4-(kinolin-8-il(1-(tiazol-4-ilmetil) piperidin-4-iliden)metil)benzamid, postupak njegovog dobivanja kao i njegova uporaba za liječenje bola, tjeskobe i depresije
SE0004101D0 (sv)	2000-11-09	New use
NO20033413D0 (no)	2003-07-30	Krystallmodifisering av et syklisk depsipeptid med forbedret aktivitet
UY28129A1 (es)	2004-07-30	Complejos de e.-2-metoxi.-n-(3-(4-(3-metil-4-(6-metil piridin-3- iloxi)fenilamino)quinazolin-6-il)alil)acetamida, su procedimiento de producción y uso
SE0000303D0 (sv)	2000-01-31	Novel compounds
SE0301885D0 (sv)	2003-06-25	New use IV
ATE299027T1 (de)	2005-07-15	Verwendung von übersulfatierten polysacchariden als hiv-hemmer
DE602004023861D1 (de)	2009-12-10	Verwendung von oxcarbazepin zur verbesserung des schlafes bei patienten die an chronischem schmerz leiden
UY27475A1 (es)	2003-06-30	Amidas de ácido piperazinciclohexanocarboxílico sustituidas y su utilización
SE0401716D0 (sv)	2004-07-02	New compounds

EE05302B1 - 4-fluoro-N-(indaan-2-l)bensamiidi kasutamine ja protsess ravimi valmistamiseks - Google Patents