EE05559B1 - IL6R/IL6 kimri kasutamine ravimi valmistamiseks, mis on ette nhtud neuroloogiliste haiguste ja hirete ravimiseks ja/v?i vltimiseks - Google Patents
IL6R/IL6 kimri kasutamine ravimi valmistamiseks, mis on ette nhtud neuroloogiliste haiguste ja hirete ravimiseks ja/v?i vltimiseksInfo
- Publication number
- EE05559B1 EE05559B1 EEP200100689A EEP200100689A EE05559B1 EE 05559 B1 EE05559 B1 EE 05559B1 EE P200100689 A EEP200100689 A EE P200100689A EE P200100689 A EEP200100689 A EE P200100689A EE 05559 B1 EE05559 B1 EE 05559B1
- Authority
- EE
- Estonia
- Prior art keywords
- disorders
- prevention
- treatment
- il6r
- kim
- Prior art date
Links
- 208000012902 Nervous system disease Diseases 0.000 title abstract 4
- 208000025966 Neurological disease Diseases 0.000 title abstract 4
- 230000002265 prevention Effects 0.000 title abstract 2
- 101000599048 Homo sapiens Interleukin-6 receptor subunit alpha Proteins 0.000 title 1
- 102100037792 Interleukin-6 receptor subunit alpha Human genes 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/204—IL-6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL13058699A IL130586A0 (en) | 1999-06-21 | 1999-06-21 | IL6RIL6 chimera for the treatment of demyelinating diseases |
| PCT/IL2000/000363 WO2000078331A2 (en) | 1999-06-21 | 2000-06-21 | Il6ril6 chimera for the treatment of neurodegenerative diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EE200100689A EE200100689A (et) | 2003-02-17 |
| EE05559B1 true EE05559B1 (et) | 2012-08-15 |
Family
ID=11072949
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200100689A EE05559B1 (et) | 1999-06-21 | 2000-06-21 | IL6R/IL6 kimri kasutamine ravimi valmistamiseks, mis on ette nhtud neuroloogiliste haiguste ja hirete ravimiseks ja/v?i vltimiseks |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7201896B1 (et) |
| EP (1) | EP1185293B1 (et) |
| JP (1) | JP4846148B2 (et) |
| KR (1) | KR100678290B1 (et) |
| CN (1) | CN1164328C (et) |
| AT (1) | ATE306280T1 (et) |
| AU (1) | AU778662B2 (et) |
| BR (1) | BR0011363A (et) |
| CA (1) | CA2374997C (et) |
| DE (1) | DE60023139T2 (et) |
| DK (1) | DK1185293T3 (et) |
| EA (1) | EA004626B1 (et) |
| EE (1) | EE05559B1 (et) |
| ES (1) | ES2250140T3 (et) |
| IL (2) | IL130586A0 (et) |
| MX (1) | MXPA02000116A (et) |
| NO (1) | NO329028B1 (et) |
| UA (1) | UA76695C2 (et) |
| WO (1) | WO2000078331A2 (et) |
| ZA (1) | ZA200109488B (et) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL154777A0 (en) * | 2000-09-14 | 2003-10-31 | Applied Research Systems | Il-6 receptor/il-6 chimera in huntington's disease |
| DE10107737A1 (de) * | 2001-02-16 | 2002-09-05 | S Rose John Christian Albrecht | Verwendung eines Konjugats aus IL-6 und einem IL-6 Rezeptor zur Tumortherapie |
| US7785819B2 (en) * | 2001-04-10 | 2010-08-31 | The Board Of Trustees Of The Leland Stanford Junior University | Therapeutic and diagnostic uses of antibody specificity profiles |
| IL147412A0 (en) * | 2001-12-31 | 2002-08-14 | Yeda Res & Dev | The use of il6r/il6 chimera in nerve cell regeneration |
| AU2004247961B2 (en) | 2003-06-12 | 2010-06-24 | Yeda Research & Development Co.Ltd | Enhancement of oligodendrocyte differentiation |
| EP1692273A1 (en) * | 2003-11-14 | 2006-08-23 | Mats J. Olsson | Melanocytes in therapy of neurodegenerative diseases |
| IL161672A0 (en) * | 2004-04-29 | 2004-09-27 | Yeda Res & Dev | Compositions and methods for therapy of chemotherapy-induced neuropathy |
| IL163856A0 (en) * | 2004-09-01 | 2005-12-18 | Applied Research Systems | Use of IL-6 in vascular complications |
| WO2017139736A1 (en) * | 2016-02-12 | 2017-08-17 | Als Therapy Development Institute | Measurement of als progression based on kinetic data |
| JP7064197B2 (ja) * | 2016-09-23 | 2022-05-10 | 国立大学法人大阪大学 | シュワン細胞分化促進剤及び末梢神経再生促進剤 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL122818A0 (en) * | 1997-07-10 | 1998-08-16 | Yeda Res & Dev | Chimeric interleukin-6 soluble receptor/ligand protein analogs thereof and uses thereof |
| JPH1148413A (ja) | 1997-08-06 | 1999-02-23 | Dainippon Printing Co Ltd | ホルムアルデヒド捕捉壁紙およびその製造方法 |
| JP4859153B2 (ja) * | 1999-02-25 | 2012-01-25 | 東ソー株式会社 | 新規神経系細胞分化促進剤 |
-
1999
- 1999-06-21 IL IL13058699A patent/IL130586A0/xx unknown
-
2000
- 2000-06-21 WO PCT/IL2000/000363 patent/WO2000078331A2/en not_active Ceased
- 2000-06-21 CA CA2374997A patent/CA2374997C/en not_active Expired - Fee Related
- 2000-06-21 KR KR1020017015303A patent/KR100678290B1/ko not_active Expired - Fee Related
- 2000-06-21 CN CNB008089108A patent/CN1164328C/zh not_active Expired - Fee Related
- 2000-06-21 US US09/980,823 patent/US7201896B1/en not_active Expired - Fee Related
- 2000-06-21 EP EP00939022A patent/EP1185293B1/en not_active Expired - Lifetime
- 2000-06-21 DK DK00939022T patent/DK1185293T3/da active
- 2000-06-21 ES ES00939022T patent/ES2250140T3/es not_active Expired - Lifetime
- 2000-06-21 AU AU54231/00A patent/AU778662B2/en not_active Ceased
- 2000-06-21 AT AT00939022T patent/ATE306280T1/de active
- 2000-06-21 DE DE60023139T patent/DE60023139T2/de not_active Expired - Lifetime
- 2000-06-21 BR BR0011363-8A patent/BR0011363A/pt not_active Application Discontinuation
- 2000-06-21 EE EEP200100689A patent/EE05559B1/et not_active IP Right Cessation
- 2000-06-21 JP JP2001504394A patent/JP4846148B2/ja not_active Expired - Fee Related
- 2000-06-21 MX MXPA02000116A patent/MXPA02000116A/es active IP Right Grant
- 2000-06-21 UA UA2002010458A patent/UA76695C2/uk unknown
- 2000-06-21 EA EA200200063A patent/EA004626B1/ru not_active IP Right Cessation
-
2001
- 2001-11-16 ZA ZA200109488A patent/ZA200109488B/xx unknown
- 2001-11-20 NO NO20015673A patent/NO329028B1/no not_active IP Right Cessation
- 2001-12-19 IL IL147188A patent/IL147188A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR100678290B1 (ko) | 2007-02-05 |
| DK1185293T3 (da) | 2005-12-27 |
| CA2374997C (en) | 2010-04-13 |
| IL147188A (en) | 2015-09-24 |
| EE200100689A (et) | 2003-02-17 |
| JP2003502382A (ja) | 2003-01-21 |
| ES2250140T3 (es) | 2006-04-16 |
| US7201896B1 (en) | 2007-04-10 |
| MXPA02000116A (es) | 2003-07-21 |
| CN1164328C (zh) | 2004-09-01 |
| WO2000078331A2 (en) | 2000-12-28 |
| NO329028B1 (no) | 2010-08-02 |
| DE60023139D1 (de) | 2006-02-23 |
| HK1047549A1 (en) | 2003-02-28 |
| JP4846148B2 (ja) | 2011-12-28 |
| DE60023139T2 (de) | 2006-05-04 |
| NO20015673D0 (no) | 2001-11-20 |
| EA200200063A1 (ru) | 2002-06-27 |
| AU778662B2 (en) | 2004-12-16 |
| WO2000078331A3 (en) | 2001-07-05 |
| UA76695C2 (uk) | 2006-09-15 |
| ATE306280T1 (de) | 2005-10-15 |
| BR0011363A (pt) | 2002-02-26 |
| IL130586A0 (en) | 2000-06-01 |
| NO20015673L (no) | 2001-12-17 |
| ZA200109488B (en) | 2002-11-18 |
| CN1364088A (zh) | 2002-08-14 |
| EP1185293A2 (en) | 2002-03-13 |
| EP1185293B1 (en) | 2005-10-12 |
| KR20020013901A (ko) | 2002-02-21 |
| EA004626B1 (ru) | 2004-06-24 |
| CA2374997A1 (en) | 2000-12-28 |
| AU5423100A (en) | 2001-01-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB1A | Change in the ownership or in the address of the owner | ||
| HC1A | Change of owner name | ||
| MM4A | Lapsed by not paying the annual fees |
Effective date: 20160621 |