ATE306280T1 - Verwendung von il6r- il6 chimären für die behandlung von neurodegenerativen erkankungen - Google Patents
Verwendung von il6r- il6 chimären für die behandlung von neurodegenerativen erkankungenInfo
- Publication number
- ATE306280T1 ATE306280T1 AT00939022T AT00939022T ATE306280T1 AT E306280 T1 ATE306280 T1 AT E306280T1 AT 00939022 T AT00939022 T AT 00939022T AT 00939022 T AT00939022 T AT 00939022T AT E306280 T1 ATE306280 T1 AT E306280T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- il6r
- chimeras
- neurodegenerative diseases
- disorders
- Prior art date
Links
- 208000015122 neurodegenerative disease Diseases 0.000 title 1
- 208000012902 Nervous system disease Diseases 0.000 abstract 2
- 208000025966 Neurological disease Diseases 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/204—IL-6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL13058699A IL130586A0 (en) | 1999-06-21 | 1999-06-21 | IL6RIL6 chimera for the treatment of demyelinating diseases |
| PCT/IL2000/000363 WO2000078331A2 (en) | 1999-06-21 | 2000-06-21 | Il6ril6 chimera for the treatment of neurodegenerative diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE306280T1 true ATE306280T1 (de) | 2005-10-15 |
Family
ID=11072949
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00939022T ATE306280T1 (de) | 1999-06-21 | 2000-06-21 | Verwendung von il6r- il6 chimären für die behandlung von neurodegenerativen erkankungen |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7201896B1 (de) |
| EP (1) | EP1185293B1 (de) |
| JP (1) | JP4846148B2 (de) |
| KR (1) | KR100678290B1 (de) |
| CN (1) | CN1164328C (de) |
| AT (1) | ATE306280T1 (de) |
| AU (1) | AU778662B2 (de) |
| BR (1) | BR0011363A (de) |
| CA (1) | CA2374997C (de) |
| DE (1) | DE60023139T2 (de) |
| DK (1) | DK1185293T3 (de) |
| EA (1) | EA004626B1 (de) |
| EE (1) | EE05559B1 (de) |
| ES (1) | ES2250140T3 (de) |
| IL (2) | IL130586A0 (de) |
| MX (1) | MXPA02000116A (de) |
| NO (1) | NO329028B1 (de) |
| UA (1) | UA76695C2 (de) |
| WO (1) | WO2000078331A2 (de) |
| ZA (1) | ZA200109488B (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2262680T3 (es) * | 2000-09-14 | 2006-12-01 | Ares Trading S.A. | Uso de una quimera il-6r/il-6 en la enfermedad de huntington. |
| DE10107737A1 (de) * | 2001-02-16 | 2002-09-05 | S Rose John Christian Albrecht | Verwendung eines Konjugats aus IL-6 und einem IL-6 Rezeptor zur Tumortherapie |
| JP4594588B2 (ja) * | 2001-04-10 | 2010-12-08 | ザ ボード オブ トラスティーズ オブ ザ リランド スタンフォード ジュニア ユニヴァーシティ | 抗体特異的プロファイルの治療的および診断的使用方法 |
| IL147412A0 (en) * | 2001-12-31 | 2002-08-14 | Yeda Res & Dev | The use of il6r/il6 chimera in nerve cell regeneration |
| US8617887B2 (en) | 2003-06-12 | 2013-12-31 | Yeda Research And Development Co. Ltd | Method of generating oligodendrocytes from neurosphere cells |
| US20070071727A1 (en) * | 2003-11-14 | 2007-03-29 | Olsson Mats J | Melanocytes in therapy of neurodegenerative diseases |
| IL161672A0 (en) | 2004-04-29 | 2004-09-27 | Yeda Res & Dev | Compositions and methods for therapy of chemotherapy-induced neuropathy |
| IL163856A0 (en) * | 2004-09-01 | 2005-12-18 | Applied Research Systems | Use of IL-6 in vascular complications |
| CN108778121A (zh) * | 2016-02-12 | 2018-11-09 | Als治疗发展研究所 | 基于动力学数据评估als病情进展 |
| US11207354B2 (en) | 2016-09-23 | 2021-12-28 | Osaka University | Schwann cell differentiation promoting agent and a peripheral nerve regeneration promoting agent |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL122818A0 (en) * | 1997-07-10 | 1998-08-16 | Yeda Res & Dev | Chimeric interleukin-6 soluble receptor/ligand protein analogs thereof and uses thereof |
| JPH1148413A (ja) | 1997-08-06 | 1999-02-23 | Dainippon Printing Co Ltd | ホルムアルデヒド捕捉壁紙およびその製造方法 |
| JP4859153B2 (ja) * | 1999-02-25 | 2012-01-25 | 東ソー株式会社 | 新規神経系細胞分化促進剤 |
-
1999
- 1999-06-21 IL IL13058699A patent/IL130586A0/xx unknown
-
2000
- 2000-06-21 UA UA2002010458A patent/UA76695C2/uk unknown
- 2000-06-21 CN CNB008089108A patent/CN1164328C/zh not_active Expired - Fee Related
- 2000-06-21 BR BR0011363-8A patent/BR0011363A/pt not_active Application Discontinuation
- 2000-06-21 AU AU54231/00A patent/AU778662B2/en not_active Ceased
- 2000-06-21 DK DK00939022T patent/DK1185293T3/da active
- 2000-06-21 EA EA200200063A patent/EA004626B1/ru not_active IP Right Cessation
- 2000-06-21 DE DE60023139T patent/DE60023139T2/de not_active Expired - Lifetime
- 2000-06-21 ES ES00939022T patent/ES2250140T3/es not_active Expired - Lifetime
- 2000-06-21 US US09/980,823 patent/US7201896B1/en not_active Expired - Fee Related
- 2000-06-21 MX MXPA02000116A patent/MXPA02000116A/es active IP Right Grant
- 2000-06-21 JP JP2001504394A patent/JP4846148B2/ja not_active Expired - Fee Related
- 2000-06-21 AT AT00939022T patent/ATE306280T1/de active
- 2000-06-21 WO PCT/IL2000/000363 patent/WO2000078331A2/en not_active Ceased
- 2000-06-21 CA CA2374997A patent/CA2374997C/en not_active Expired - Fee Related
- 2000-06-21 EP EP00939022A patent/EP1185293B1/de not_active Expired - Lifetime
- 2000-06-21 EE EEP200100689A patent/EE05559B1/xx not_active IP Right Cessation
- 2000-06-21 KR KR1020017015303A patent/KR100678290B1/ko not_active Expired - Fee Related
-
2001
- 2001-11-16 ZA ZA200109488A patent/ZA200109488B/xx unknown
- 2001-11-20 NO NO20015673A patent/NO329028B1/no not_active IP Right Cessation
- 2001-12-19 IL IL147188A patent/IL147188A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200109488B (en) | 2002-11-18 |
| CA2374997A1 (en) | 2000-12-28 |
| KR20020013901A (ko) | 2002-02-21 |
| EP1185293B1 (de) | 2005-10-12 |
| EP1185293A2 (de) | 2002-03-13 |
| CN1364088A (zh) | 2002-08-14 |
| WO2000078331A2 (en) | 2000-12-28 |
| CN1164328C (zh) | 2004-09-01 |
| BR0011363A (pt) | 2002-02-26 |
| NO329028B1 (no) | 2010-08-02 |
| NO20015673L (no) | 2001-12-17 |
| NO20015673D0 (no) | 2001-11-20 |
| KR100678290B1 (ko) | 2007-02-05 |
| WO2000078331A3 (en) | 2001-07-05 |
| US7201896B1 (en) | 2007-04-10 |
| EE05559B1 (et) | 2012-08-15 |
| DE60023139D1 (de) | 2006-02-23 |
| AU778662B2 (en) | 2004-12-16 |
| AU5423100A (en) | 2001-01-09 |
| HK1047549A1 (en) | 2003-02-28 |
| EE200100689A (et) | 2003-02-17 |
| IL130586A0 (en) | 2000-06-01 |
| UA76695C2 (uk) | 2006-09-15 |
| MXPA02000116A (es) | 2003-07-21 |
| DK1185293T3 (da) | 2005-12-27 |
| JP4846148B2 (ja) | 2011-12-28 |
| IL147188A (en) | 2015-09-24 |
| DE60023139T2 (de) | 2006-05-04 |
| CA2374997C (en) | 2010-04-13 |
| ES2250140T3 (es) | 2006-04-16 |
| EA200200063A1 (ru) | 2002-06-27 |
| JP2003502382A (ja) | 2003-01-21 |
| EA004626B1 (ru) | 2004-06-24 |
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Legal Events
| Date | Code | Title | Description |
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| UEP | Publication of translation of european patent specification |
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