EE05644B1 - Meetod hCG puhastamiseks ja selle meetodiga puhastatud rekombinantne hCG - Google Patents

Meetod hCG puhastamiseks ja selle meetodiga puhastatud rekombinantne hCG

Info

Publication number
EE05644B1
EE05644B1 EEP200200469A EEP200200469A EE05644B1 EE 05644 B1 EE05644 B1 EE 05644B1 EE P200200469 A EEP200200469 A EE P200200469A EE P200200469 A EEP200200469 A EE P200200469A EE 05644 B1 EE05644 B1 EE 05644B1
Authority
EE
Estonia
Prior art keywords
hcg
recombinant
purifying
purified
purification
Prior art date
Application number
EEP200200469A
Other languages
English (en)
Inventor
Paradisi Gianfranco
Rossi Mara
Scaglia Laura
Original Assignee
Applied Research Systems Ars Holding N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems Ars Holding N.V. filed Critical Applied Research Systems Ars Holding N.V.
Publication of EE200200469A publication Critical patent/EE200200469A/et
Publication of EE05644B1 publication Critical patent/EE05644B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Detergent Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
EEP200200469A 2000-02-22 2001-01-22 Meetod hCG puhastamiseks ja selle meetodiga puhastatud rekombinantne hCG EE05644B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00103690 2000-02-22
PCT/EP2001/000665 WO2001062773A1 (en) 2000-02-22 2001-01-22 PROCESS OF PURIFICATION OF hCG AND RECOMBINANT hCG PURIFIED BY THAT METHOD

Publications (2)

Publication Number Publication Date
EE200200469A EE200200469A (et) 2004-04-15
EE05644B1 true EE05644B1 (et) 2013-04-15

Family

ID=8167925

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200200469A EE05644B1 (et) 2000-02-22 2001-01-22 Meetod hCG puhastamiseks ja selle meetodiga puhastatud rekombinantne hCG

Country Status (31)

Country Link
US (2) US7297777B2 (et)
EP (2) EP1257564B1 (et)
JP (1) JP4588960B2 (et)
KR (1) KR100806911B1 (et)
CN (1) CN100482679C (et)
AT (1) ATE406378T1 (et)
AU (2) AU783320B2 (et)
BG (1) BG65807B1 (et)
BR (1) BRPI0108556B8 (et)
CA (1) CA2399020A1 (et)
CY (1) CY1108460T1 (et)
CZ (1) CZ303144B6 (et)
DE (1) DE60135541D1 (et)
DK (1) DK1257564T3 (et)
EA (1) EA006605B1 (et)
EE (1) EE05644B1 (et)
ES (1) ES2307585T3 (et)
HR (1) HRP20020650B1 (et)
HU (2) HU228935B1 (et)
IL (2) IL151308A0 (et)
ME (1) ME00296B (et)
MX (1) MXPA02007871A (et)
NO (1) NO328694B1 (et)
PL (1) PL205149B1 (et)
PT (1) PT1257564E (et)
RS (1) RS50741B (et)
SI (1) SI1257564T1 (et)
SK (1) SK287146B6 (et)
UA (2) UA78488C2 (et)
WO (1) WO2001062773A1 (et)
ZA (1) ZA200206109B (et)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4588960B2 (ja) * 2000-02-22 2010-12-01 メルク セローノ ソシエテ アノニム ｈＣＧの精製方法及び本法により精製した組換えｈＣＧ
CA2582083A1 (en) * 2004-10-04 2006-04-20 Novetide, Ltd. A counterion exchange process for peptides
CN1958603B (zh) * 2005-11-04 2010-05-05 上海天伟生物制药有限公司 一种人绒毛膜促性腺素的纯化方法
EA200802426A1 (ru) * 2006-07-11 2009-04-28 Коваль, Антон Александрович Применение хорионического или лютеинизирующего гормона для профилактики или лечения возрастного гипогонадизма
CN101397339B (zh) * 2008-09-24 2012-07-25 上海天伟生物制药有限公司 糖蛋白中去除/灭活病毒的方法
TWI532495B (zh) * 2009-10-05 2016-05-11 菲瑞茵國際中心股份有限公司 藥學製劑
CN101792481B (zh) * 2010-03-12 2012-05-30 丽珠医药集团股份有限公司 一种绒毛膜促性腺激素的纯化方法
WO2012120535A2 (en) * 2011-02-03 2012-09-13 Sanzyme Limited A composition comprising highly purified chorionic gonadotropin, it's formulation and uses of the same
WO2012131306A1 (en) 2011-03-31 2012-10-04 Ferring B.V. Pharmaceutical preparation
WO2013102921A2 (en) * 2011-11-17 2013-07-11 Sanzyme Limited Hcg - newer treatment modality for type 2 diabetes mellitus (t2dm)
CN103288950A (zh) * 2012-12-28 2013-09-11 青岛九龙生物医药有限公司 改进柱分离工序洗涤液和洗脱液配比去除杂质的方法
CN104101656A (zh) * 2013-04-01 2014-10-15 上海天伟生物制药有限公司 一种促性腺激素的纯度测定方法
US20150065426A1 (en) * 2013-08-27 2015-03-05 Professional Compounding Centers Of America Testosterone Booster Transdermal Compositions
CN105968185A (zh) * 2016-07-20 2016-09-28 宁波人健药业集团股份有限公司 一种绒促性素纯化方法
CN111233999B (zh) * 2020-03-21 2024-02-23 上海浦东明炎生物技术有限公司 一种从人尿中提取人绒毛膜促性腺激素的方法
CN113398251B (zh) * 2021-07-30 2022-08-05 宁波人健药业集团股份有限公司 一种重组人绒毛膜促性腺激素冻干粉针剂及其制备方法
CN116063452A (zh) * 2023-01-03 2023-05-05 杭州浦泰生物科技有限公司 一种人绒毛膜促性腺激素高效纯化方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE148171T1 (de) * 1989-02-21 1997-02-15 Univ Washington Modifizierte formen von fortpflanzungshormonen
IT1250075B (it) * 1991-12-18 1995-03-30 Serono Cesare Ist Ricerca Composizioni farmaceutiche contenenti gonadotropine.
IT1254370B (it) * 1992-05-22 1995-09-14 Sorin Biomedica Spa Procedimento per la purificazione di proteine da sistemi cellulari.
CN1082368C (zh) * 1995-03-21 2002-04-10 应用研究系统Ars股份公司 人绒毛膜促性腺激素液体制剂
ES2166841T3 (es) 1995-03-21 2002-05-01 Applied Research Systems Formulaciones liquidas de hcg.
BR9707589A (pt) * 1996-02-20 2000-01-04 Applied Research Systems Proteìna hìbrida, molécula de dna, vetor de expressão, célula hospedeira, composição farmacêutica e processos para produzir proteìna hìbrida e para induzir maturação folicular.
IT1287138B1 (it) * 1996-11-07 1998-08-04 Ibsa Inst Biochimique Sa Procedimento per la separazione e purificazione di fsh e lh
WO1998056806A1 (en) 1997-06-12 1998-12-17 The Regents Of The University Of California A TRANSCRIPTION FACTOR COACTIVATOR PROTEIN, p/CIP
US6121428A (en) * 1997-06-13 2000-09-19 Genentech, Inc. Protein recovery
US6583109B1 (en) * 1997-06-24 2003-06-24 Robert C. Gallo Therapeutic polypeptides from β-hCG and derivatives
JP4588960B2 (ja) * 2000-02-22 2010-12-01 メルク セローノ ソシエテ アノニム ｈＣＧの精製方法及び本法により精製した組換えｈＣＧ

Also Published As

Publication number Publication date
BG107000A (en) 2003-04-30
HUP0204231A2 (hu) 2003-03-28
AU783320B2 (en) 2005-10-13
UA78488C2 (en) 2007-04-10
HRP20020650A2 (en) 2004-12-31
CA2399020A1 (en) 2001-08-30
EA200200892A1 (ru) 2003-02-27
CY1108460T1 (el) 2014-04-09
HU228935B1 (en) 2013-06-28
PT1257564E (pt) 2008-09-10
RS50741B (sr) 2010-08-31
SI1257564T1 (sl) 2008-12-31
EP1257564B1 (en) 2008-08-27
DK1257564T3 (da) 2008-10-06
ES2307585T3 (es) 2008-12-01
JP4588960B2 (ja) 2010-12-01
PL205149B1 (pl) 2010-03-31
NO20023985D0 (no) 2002-08-21
BRPI0108556B8 (pt) 2021-05-25
MEP38908A (en) 2011-02-10
DE60135541D1 (de) 2008-10-09
SK12062002A3 (sk) 2002-12-03
US20030104553A1 (en) 2003-06-05
HU1300063D0 (hu) 2003-03-28
EA006605B1 (ru) 2006-02-24
IL151308A0 (en) 2003-04-10
WO2001062773A1 (en) 2001-08-30
EP1752466A2 (en) 2007-02-14
UA86938C2 (uk) 2009-06-10
KR100806911B1 (ko) 2008-02-22
AU2006200059A1 (en) 2006-02-02
CN100482679C (zh) 2009-04-29
YU60202A (sh) 2005-09-19
AU2680401A (en) 2001-09-03
IL151308A (en) 2009-11-18
NO328694B1 (no) 2010-04-26
PL357508A1 (en) 2004-07-26
HUP0204231A3 (en) 2005-09-28
JP2003524015A (ja) 2003-08-12
ZA200206109B (en) 2003-07-31
BRPI0108556B1 (pt) 2015-04-14
ME00296B (me) 2011-05-10
HK1052016A1 (zh) 2003-08-29
SK287146B6 (sk) 2010-01-07
CZ303144B6 (cs) 2012-05-02
EP1257564A1 (en) 2002-11-20
US7297777B2 (en) 2007-11-20
CZ20022855A3 (cs) 2002-11-13
MXPA02007871A (es) 2003-02-10
NO20023985L (no) 2002-08-21
US20070299001A1 (en) 2007-12-27
ATE406378T1 (de) 2008-09-15
EP1752466A3 (en) 2012-10-10
HRP20020650B1 (en) 2011-02-28
KR20030001359A (ko) 2003-01-06
EE200200469A (et) 2004-04-15
CN1404485A (zh) 2003-03-19
BR0108556A (pt) 2003-01-28
BG65807B1 (bg) 2009-12-31

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Legal Events

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HC1A Change of owner name