EE200100394A - Ketoliidsed antibiootikumid - Google Patents

Ketoliidsed antibiootikumid

Info

Publication number
EE200100394A
EE200100394A EEP200100394A EEP200100394A EE200100394A EE 200100394 A EE200100394 A EE 200100394A EE P200100394 A EEP200100394 A EE P200100394A EE P200100394 A EEP200100394 A EE P200100394A EE 200100394 A EE200100394 A EE 200100394A
Authority
EE
Estonia
Prior art keywords
ketolide antibiotics
ketolide
antibiotics
Prior art date
Application number
EEP200100394A
Other languages
English (en)
Estonian (et)
Inventor
Kaneko Takushi
Thomas Mcmillen William
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of EE200100394A publication Critical patent/EE200100394A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Gynecology & Obstetrics (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Otolaryngology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Cephalosporin Compounds (AREA)
EEP200100394A 1999-01-27 1999-12-28 Ketoliidsed antibiootikumid EE200100394A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11734299P 1999-01-27 1999-01-27
PCT/IB1999/002051 WO2000044761A2 (fr) 1999-01-27 1999-12-28 Antibiotiques cetolides

Publications (1)

Publication Number Publication Date
EE200100394A true EE200100394A (et) 2002-10-15

Family

ID=22372371

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200100394A EE200100394A (et) 1999-01-27 1999-12-28 Ketoliidsed antibiootikumid

Country Status (39)

Country Link
US (1) US6833444B2 (fr)
EP (1) EP1147121B1 (fr)
JP (1) JP3947360B2 (fr)
KR (1) KR20020002380A (fr)
CN (1) CN1342163A (fr)
AP (1) AP2001002222A0 (fr)
AT (1) ATE256694T1 (fr)
AU (1) AU1675400A (fr)
BG (1) BG105730A (fr)
BR (1) BR9916969A (fr)
CA (1) CA2359708C (fr)
CO (1) CO5150229A1 (fr)
CZ (1) CZ20012675A3 (fr)
DE (1) DE69913738T2 (fr)
DK (1) DK1147121T3 (fr)
DZ (1) DZ3000A1 (fr)
EA (1) EA200100623A1 (fr)
EE (1) EE200100394A (fr)
ES (1) ES2212655T3 (fr)
HK (1) HK1042707A1 (fr)
HN (1) HN2000000003A (fr)
HR (1) HRP20010559A2 (fr)
HU (1) HUP0105190A3 (fr)
ID (1) ID30233A (fr)
IL (1) IL144178A0 (fr)
IS (1) IS5984A (fr)
MA (1) MA26717A1 (fr)
NO (1) NO20013680L (fr)
OA (1) OA11753A (fr)
PA (1) PA8489501A1 (fr)
PE (1) PE20001422A1 (fr)
PT (1) PT1147121E (fr)
SI (1) SI1147121T1 (fr)
SK (1) SK10172001A3 (fr)
TN (1) TNSN00007A1 (fr)
TR (1) TR200102128T2 (fr)
UY (1) UY25990A1 (fr)
WO (1) WO2000044761A2 (fr)
ZA (1) ZA200105580B (fr)

Families Citing this family (30)

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AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
DK1147121T3 (da) 1999-01-27 2004-04-13 Pfizer Prod Inc Ketolidantibiotika
US6939861B2 (en) 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
WO2000062783A2 (fr) 1999-04-16 2000-10-26 Ortho-Mcneil Pharmaceutical, Inc. Agents antibacteriens cetolides
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
BR0010680A (pt) * 1999-04-16 2002-02-19 Kosan Biosciences Inc Agentes antiinfecciosos de macrolìdeo
US6514944B2 (en) 1999-04-16 2003-02-04 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6451768B1 (en) 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
AP2001002302A0 (en) 1999-05-24 2001-10-25 Pfizer Prod Inc 13-Methyl erythromycin derivatives.
DK1167376T3 (da) 2000-06-30 2004-10-25 Pfizer Prod Inc Makrolidantibiotika
US20020115621A1 (en) 2000-08-07 2002-08-22 Wei-Gu Su Macrolide antibiotics
MXPA03005668A (es) * 2000-12-21 2004-12-03 Pliva D D Macrolidos.
PE20030438A1 (es) * 2001-09-05 2003-07-03 Hokuriku Pharmaceutical Medicamento que comprende un derivado de eritromicina como agente antituberculoso
EP3738591A3 (fr) 2003-03-10 2021-03-24 Merck Sharp & Dohme Corp. Nouveaux agents antibactériens
US20080287376A1 (en) * 2004-07-28 2008-11-20 Mohammad Salman Ketolide Derivatives as Antibacterial Agents
EA011281B1 (ru) 2004-12-21 2009-02-27 Пфайзер Продактс Инк. Макролиды
US8124744B2 (en) * 2006-05-01 2012-02-28 Taisho Pharmaceutical Co., Ltd. Macrolide derivatives
US9453042B2 (en) 2007-10-25 2016-09-27 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
CN107854477A (zh) 2008-10-24 2018-03-30 森普拉制药公司 使用含三唑的大环内酯治疗抗性疾病的方法
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
CN108310000A (zh) 2009-09-10 2018-07-24 森普拉制药公司 治疗疟疾、结核病和mac疾病的方法
US8975386B2 (en) 2010-03-22 2015-03-10 Cempra Pharmaceuticals, Inc. Crystalline forms of a macrolide, and uses therefor
CN102917708B (zh) 2010-05-20 2015-11-25 森普拉制药公司 制备大环内酯和酮内酯及其中间体的方法
KR20180110181A (ko) 2010-09-10 2018-10-08 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
SG11201405895UA (en) 2012-03-27 2014-10-30 Cempra Pharmaceuticals Inc Parenteral formulations for administering macrolide antibiotics
US9861616B2 (en) 2013-03-14 2018-01-09 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
MX356772B (es) 2013-03-15 2018-06-13 Cempra Pharmaceuticals Inc Procesos convergentes para la preparacion de agentes antibacterianos macrolidos.
WO2014156549A1 (fr) 2013-03-28 2014-10-02 不二製油株式会社 Composition de gel de protéine d'ambérique et aliment de type fromage
CN106518939B (zh) * 2015-09-14 2019-12-31 江苏奥赛康药业有限公司 一种制备Solithromycin化合物的方法
CN110234323A (zh) * 2016-10-04 2019-09-13 Ti生物制药有限公司 具有抗菌活性的酮内酯

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US4474768A (en) 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
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UA51730C2 (uk) 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
FR2757168B1 (fr) 1996-12-12 1999-06-11 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
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FR2771008B1 (fr) * 1997-11-17 2000-04-28 Hoechst Marion Roussel Inc Utilisation des ketolides pour la preparation de compositions pharmaceutiques destinees a prevenir les complications thrombotiques arterielles liees a l'atherosclerose
AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
FR2777282B1 (fr) 1998-04-08 2001-04-20 Hoechst Marion Roussel Inc Nouveaux derives de la 2-fluoro 3-de((2,6-dideoxy 3-c-methyl 3-0-methyl-alpha-l-ribohexopyranosyl) oxyl) 6-o-methyl 3-oxo erythromycine, leur procede de preparation et leur application a la synthese de principes actifs de medicaments
DE69926005T2 (de) 1998-09-22 2006-05-18 Pfizer Products Inc., Groton Carbamat- und carbazatketolidantibiotika
US6100240A (en) 1998-10-09 2000-08-08 Pfizer Inc Macrolide derivatives
FR2785612A1 (fr) 1998-11-10 2000-05-12 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
EA200100396A1 (ru) 1998-11-03 2001-10-22 Пфайзер Продактс Инк. Новые макролидные антибиотики
FR2786188B1 (fr) 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
WO2000034297A1 (fr) 1998-12-10 2000-06-15 Pfizer Products Inc. Antibiotiques a base de cetolides de carbamate et de carbazate
DK1147121T3 (da) 1999-01-27 2004-04-13 Pfizer Prod Inc Ketolidantibiotika
FR2789392B1 (fr) * 1999-02-04 2001-10-05 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
WO2000062783A2 (fr) 1999-04-16 2000-10-26 Ortho-Mcneil Pharmaceutical, Inc. Agents antibacteriens cetolides
BR0010680A (pt) 1999-04-16 2002-02-19 Kosan Biosciences Inc Agentes antiinfecciosos de macrolìdeo
US6355620B1 (en) 1999-05-14 2002-03-12 Abbott Laboratories C-2 modified erythromycin derivatives
AP2001002302A0 (en) 1999-05-24 2001-10-25 Pfizer Prod Inc 13-Methyl erythromycin derivatives.
EP1114826A3 (fr) 1999-12-29 2001-10-31 Pfizer Products Inc. Macrolides antibactériennes et prokinétiques
EP1122261A3 (fr) 2000-01-31 2001-09-26 Pfizer Products Inc. Macrolides antibactériennes à 13 ou 14 chainons
US20020061856A1 (en) 2000-04-24 2002-05-23 Yong-Jin Wu Novel tricyclic erythromycin derivatives
DK1167376T3 (da) 2000-06-30 2004-10-25 Pfizer Prod Inc Makrolidantibiotika

Also Published As

Publication number Publication date
OA11753A (en) 2005-07-19
DK1147121T3 (da) 2004-04-13
HN2000000003A (es) 2001-02-02
EP1147121A2 (fr) 2001-10-24
EA200100623A1 (ru) 2002-02-28
JP3947360B2 (ja) 2007-07-18
ID30233A (id) 2001-11-15
DE69913738T2 (de) 2004-06-17
IL144178A0 (en) 2002-05-23
US20020156027A1 (en) 2002-10-24
CA2359708C (fr) 2005-10-25
KR20020002380A (ko) 2002-01-09
EP1147121B1 (fr) 2003-12-17
UY25990A1 (es) 2000-09-29
PA8489501A1 (es) 2000-09-29
ZA200105580B (en) 2003-02-17
HUP0105190A2 (hu) 2002-04-29
WO2000044761A3 (fr) 2001-01-04
AU1675400A (en) 2000-08-18
HRP20010559A2 (en) 2002-08-31
PE20001422A1 (es) 2000-12-18
SI1147121T1 (en) 2004-04-30
US6833444B2 (en) 2004-12-21
AP2001002222A0 (en) 2001-09-30
CN1342163A (zh) 2002-03-27
BR9916969A (pt) 2001-11-06
BG105730A (en) 2002-03-29
JP2002535414A (ja) 2002-10-22
TNSN00007A1 (fr) 2005-11-10
HK1042707A1 (zh) 2002-08-23
SK10172001A3 (sk) 2002-06-04
NO20013680D0 (no) 2001-07-26
NO20013680L (no) 2001-09-19
WO2000044761A2 (fr) 2000-08-03
DE69913738D1 (de) 2004-01-29
HUP0105190A3 (en) 2003-03-28
PT1147121E (pt) 2004-04-30
TR200102128T2 (tr) 2001-12-21
CA2359708A1 (fr) 2000-08-03
CO5150229A1 (es) 2002-04-29
ATE256694T1 (de) 2004-01-15
ES2212655T3 (es) 2004-07-16
DZ3000A1 (fr) 2004-03-27
MA26717A1 (fr) 2004-12-20
CZ20012675A3 (cs) 2002-04-17
IS5984A (is) 2001-06-28

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