EE200300519A - Meetod pioglitasooni kui suhkurtõvevastase aine saamiseks - Google Patents

Meetod pioglitasooni kui suhkurtõvevastase aine saamiseks

Info

Publication number
EE200300519A
EE200300519A EEP200300519A EEP200300519A EE200300519A EE 200300519 A EE200300519 A EE 200300519A EE P200300519 A EEP200300519 A EE P200300519A EE P200300519 A EEP200300519 A EE P200300519A EE 200300519 A EE200300519 A EE 200300519A
Authority
EE
Estonia
Prior art keywords
sup
formula
group
residue
general formula
Prior art date
Application number
EEP200300519A
Other languages
English (en)
Estonian (et)
Inventor
Halama Ales
Hejtm�nkov� Ludmila
Lustig Petr
Richter Jindrich
Srsnov� Lucie
Jirman Josef
Original Assignee
L�civa, a.s.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CZ20011502A external-priority patent/CZ291364B6/cs
Priority claimed from CZ20011501A external-priority patent/CZ20011501A3/cs
Application filed by L�civa, a.s. filed Critical L�civa, a.s.
Publication of EE200300519A publication Critical patent/EE200300519A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Pyridine Compounds (AREA)
EEP200300519A 2001-04-26 2002-04-25 Meetod pioglitasooni kui suhkurtõvevastase aine saamiseks EE200300519A (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CZ20011502A CZ291364B6 (cs) 2001-04-26 2001-04-26 Způsob výroby antidiabetika
CZ20011501A CZ20011501A3 (cs) 2001-04-26 2001-04-26 Způsob výroby meziproduktu pro výrobu antidiabetika
PCT/CZ2002/000024 WO2002088120A1 (en) 2001-04-26 2002-04-25 Method for obtaining pioglitazone as an antidiabetic agent

Publications (1)

Publication Number Publication Date
EE200300519A true EE200300519A (et) 2004-02-16

Family

ID=25746959

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200300519A EE200300519A (et) 2001-04-26 2002-04-25 Meetod pioglitasooni kui suhkurtõvevastase aine saamiseks

Country Status (11)

Country Link
US (1) US7009057B2 (de)
EP (1) EP1387843B1 (de)
AT (1) ATE355286T1 (de)
AU (1) AU2002311057A1 (de)
DE (1) DE60218449D1 (de)
EE (1) EE200300519A (de)
HU (1) HUP0400091A2 (de)
PL (1) PL363738A1 (de)
RU (1) RU2281285C2 (de)
SK (1) SK14452003A3 (de)
WO (1) WO2002088120A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60316152D1 (de) 2002-07-16 2007-10-18 Cadila Healthcare Ltd Prozess zur herstellung von pioglitazon via verschiedene zwischenstufen
US8993773B2 (en) 2002-07-16 2015-03-31 Cadila Healthcare Limited Process to prepare pioglitazone via several novel intermediates
WO2004108721A1 (en) * 2003-04-01 2004-12-16 Sun Pharmaceutical Industries Limited Process for the preparation of 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl] methyl]-2,4-thiazolidinedione
ES2219180B1 (es) * 2003-05-09 2006-03-01 Medichem, S.A. Compuesto intermedio util para la preparacion de pioglitazona.
US7230016B2 (en) 2003-05-13 2007-06-12 Synthon Ip Inc. Pioglitazone salts, such as pioglitazone sulfate, and pharmaceutical compositions and processes using the same
CN1812988A (zh) * 2003-05-13 2006-08-02 斯索恩有限公司 制备噻唑烷二酮衍生物的方法及其化合物
US20070078170A1 (en) * 2003-08-28 2007-04-05 Khanduri Chandra H Process for the preparation of pioglitazone
CN1319956C (zh) * 2003-09-12 2007-06-06 深圳市海粤门生物科技开发有限公司 一种噻唑烷二酮的衍生物及其药用制剂的制备方法和应用
EP1716144A2 (de) 2004-02-20 2006-11-02 Synthon B.V. Verfahren zur herstellung von pioglitazon und verbindungen des verfahrens
US7402713B2 (en) * 2006-03-07 2008-07-22 E.I. Du Pont De Nemours And Company Processes for conversion of tyrosine to p-hydroxystyrene and p-acetoxystyrene
WO2007109037A2 (en) 2006-03-16 2007-09-27 Metabolic Solutions Development Company Thiazolidinedione analogues for the treatment of hypertension and for lowering lipids
UA96441C2 (ru) 2006-03-16 2011-11-10 Метаболик Солюшнз Девелопмент Компани Фармацевтическая композиция, которая содержит аналог тиазолидиндиона митоглитазон, для лечения заболеваний, опосредованных метаболическим воспалением
KR100791400B1 (ko) 2006-09-06 2008-01-07 동우신테크 주식회사 티아졸리딘디온 유도체의 제조방법
US8304441B2 (en) 2007-09-14 2012-11-06 Metabolic Solutions Development Company, Llc Thiazolidinedione analogues for the treatment of metabolic diseases
KR101537830B1 (ko) 2007-09-14 2015-07-17 메타볼릭 솔루션스 디벨롭먼트 컴퍼니, 엘엘씨 고혈압 치료용 티아졸리딘디온 유사체
WO2009148195A1 (en) * 2008-06-02 2009-12-10 Daebong Ls, Ltd. 5-(4-hydroxybenzyl)thiazolidine-2,4-dione as intermediate for synthesis of thiazolidinedione based compounds and process for preparing the same
RU2564661C2 (ru) 2009-12-15 2015-10-10 МЕТАБОЛИК СОЛЮШНЗ ДЕВЕЛОПМЕНТ КОМПАНИ, ЭлЭлСи Соли тиазолидиндиона со сниженным сродством к ppar для лечения нарушений обмена веществ
CN108003090A (zh) * 2018-01-05 2018-05-08 白银亿尔精细化工有限公司 一种制备4-[2-(5-乙基-2-吡啶基)乙氧基]硝基苯的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57209274A (en) 1981-06-16 1982-12-22 Takeda Chem Ind Ltd Urea derivative, its preparation and its use
WO1986006069A1 (fr) * 1985-04-09 1986-10-23 Takeda Chemical Industries, Ltd. Derives de thiazolidinedione, leur procede de preparation et composition medicinale les contenant
AR240698A1 (es) 1985-01-19 1990-09-28 Takeda Chemical Industries Ltd Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales
JPS62205054A (ja) 1986-03-05 1987-09-09 Takeda Chem Ind Ltd 尿素誘導体
US5952509A (en) * 1996-06-27 1999-09-14 Takeda Chemical Industries, Ltd. Production of benzaldehyde compounds
JP4316787B2 (ja) 2000-01-11 2009-08-19 壽製薬株式会社 エーテル又はアミド誘導体、その製法並びにそれを含有する糖尿病治療剤、

Also Published As

Publication number Publication date
WO2002088120A1 (en) 2002-11-07
RU2003134542A (ru) 2005-06-10
WO2002088120B1 (en) 2004-02-26
DE60218449D1 (de) 2007-04-12
RU2281285C2 (ru) 2006-08-10
EP1387843A1 (de) 2004-02-11
SK14452003A3 (sk) 2004-04-06
PL363738A1 (en) 2004-11-29
US7009057B2 (en) 2006-03-07
AU2002311057A1 (en) 2002-11-11
US20050043360A1 (en) 2005-02-24
ATE355286T1 (de) 2006-03-15
EP1387843B1 (de) 2007-02-28
HUP0400091A2 (hu) 2004-06-28

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Legal Events

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HC1A Change of owner name