EE200400044A - Struktuuripõhised ravimite kujundusmeetodid identifitseerimaks D-Ala-D-Ala ligaasi inhibiitoreid kui antibakteriaalseid ravimeid - Google Patents

Struktuuripõhised ravimite kujundusmeetodid identifitseerimaks D-Ala-D-Ala ligaasi inhibiitoreid kui antibakteriaalseid ravimeid

Info

Publication number
EE200400044A
EE200400044A EEP200400044A EEP200400044A EE200400044A EE 200400044 A EE200400044 A EE 200400044A EE P200400044 A EEP200400044 A EE P200400044A EE P200400044 A EEP200400044 A EE P200400044A EE 200400044 A EE200400044 A EE 200400044A
Authority
EE
Estonia
Prior art keywords
ala
identify
drug design
based drug
design methods
Prior art date
Application number
EEP200400044A
Other languages
English (en)
Inventor
A. Navia Manuel
J. Ala Paul
P. Griffith James
A. Ali Janid
H. Faerman Carlos
T. Moe Scott
S. Magee Andrew
R. Connelly Patrick
Perola Emanuele
Original Assignee
Essential Therapeutics, Inc.
Pliva D.D.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Essential Therapeutics, Inc., Pliva D.D. filed Critical Essential Therapeutics, Inc.
Publication of EE200400044A publication Critical patent/EE200400044A/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EEP200400044A 2001-06-28 2002-06-28 Struktuuripõhised ravimite kujundusmeetodid identifitseerimaks D-Ala-D-Ala ligaasi inhibiitoreid kui antibakteriaalseid ravimeid EE200400044A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30167601P 2001-06-28 2001-06-28
PCT/US2002/020465 WO2003002063A2 (en) 2001-06-28 2002-06-28 Structure-based drug design methods for identifying d-ala-d-ala ligase inhibitors as antibacterial drugs

Publications (1)

Publication Number Publication Date
EE200400044A true EE200400044A (et) 2004-10-15

Family

ID=23164377

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200400044A EE200400044A (et) 2001-06-28 2002-06-28 Struktuuripõhised ravimite kujundusmeetodid identifitseerimaks D-Ala-D-Ala ligaasi inhibiitoreid kui antibakteriaalseid ravimeid

Country Status (16)

Country Link
US (2) US20030119061A1 (et)
EP (1) EP1412516A4 (et)
CN (1) CN1268765C (et)
BG (1) BG108549A (et)
BR (1) BR0211312A (et)
CA (1) CA2451837A1 (et)
CZ (1) CZ200441A3 (et)
EA (1) EA007612B1 (et)
EE (1) EE200400044A (et)
HU (1) HUP0600158A2 (et)
IL (1) IL159539A0 (et)
MX (1) MXPA04000157A (et)
PL (1) PL367484A1 (et)
SK (1) SK282004A3 (et)
WO (1) WO2003002063A2 (et)
YU (1) YU102403A (et)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8329060B2 (en) * 2008-10-22 2012-12-11 General Electric Company Blue-green and green phosphors for lighting applications
US20170314007A1 (en) * 2014-09-30 2017-11-02 China Three Gorges University Medicament design pocket of ornithine decarboxylase and application of medicament design pocket
CN108504647B (zh) * 2018-03-09 2021-11-05 中山大学 一种dna促旋酶的药物结合口袋及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6251620B1 (en) * 1995-08-30 2001-06-26 Ariad Pharmaceuticals, Inc. Three dimensional structure of a ZAP tyrosine protein kinase fragment and modeling methods
US6037117A (en) * 1997-01-31 2000-03-14 Smithkline Beecham Corporation Methods using the Staphylococcus aureus glycyl tRNA synthetase crystalline structure
US6183121B1 (en) * 1997-08-14 2001-02-06 Vertex Pharmaceuticals Inc. Hepatitis C virus helicase crystals and coordinates that define helicase binding pockets

Also Published As

Publication number Publication date
PL367484A1 (en) 2005-02-21
CZ200441A3 (cs) 2004-08-18
EP1412516A4 (en) 2004-09-08
EP1412516A2 (en) 2004-04-28
US20070207512A1 (en) 2007-09-06
US20030119061A1 (en) 2003-06-26
WO2003002063A3 (en) 2003-02-20
CA2451837A1 (en) 2003-01-09
HUP0600158A2 (en) 2006-05-29
CN1539020A (zh) 2004-10-20
MXPA04000157A (es) 2005-06-06
BG108549A (bg) 2005-02-28
CN1268765C (zh) 2006-08-09
EA200400093A1 (ru) 2005-06-30
EA007612B1 (ru) 2006-12-29
IL159539A0 (en) 2004-06-01
WO2003002063A2 (en) 2003-01-09
SK282004A3 (sk) 2005-06-02
YU102403A (sh) 2006-08-17
BR0211312A (pt) 2004-07-13

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