EE200400065A - Atasanaviiri kasutamine HIV-i ravis - Google Patents

Atasanaviiri kasutamine HIV-i ravis

Info

Publication number: EE200400065A
Authority: EE; Estonia
Prior art keywords: hiv; atazanavir; protease inhibitor; treatment; triglyceride levels
Prior art date: 2001-08-31

Application number

EEP200400065A

Other languages

English (en)

Inventor

M. Bechtold Clifford

Original Assignee

Bristol-Myers Squibb Company

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-08-31

Filing date

2002-08-21

Publication date

2004-06-15

2002-08-21 Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company

2004-06-15 Publication of EE200400065A publication Critical patent/EE200400065A/et

Links

AXRYRYVKAWYZBR-UHFFFAOYSA-N Atazanavir Natural products C=1C=C(C=2N=CC=CC=2)C=CC=1CN(NC(=O)C(NC(=O)OC)C(C)(C)C)CC(O)C(NC(=O)C(NC(=O)OC)C(C)(C)C)CC1=CC=CC=C1 AXRYRYVKAWYZBR-UHFFFAOYSA-N 0.000 title abstract 3
108010019625 Atazanavir Sulfate Proteins 0.000 title abstract 3
229960003277 atazanavir Drugs 0.000 title abstract 3
AXRYRYVKAWYZBR-GASGPIRDSA-N atazanavir Chemical compound C([C@H](NC(=O)[C@@H](NC(=O)OC)C(C)(C)C)[C@@H](O)CN(CC=1C=CC(=CC=1)C=1N=CC=CC=1)NC(=O)[C@@H](NC(=O)OC)C(C)(C)C)C1=CC=CC=C1 AXRYRYVKAWYZBR-GASGPIRDSA-N 0.000 title abstract 3
229940122440 HIV protease inhibitor Drugs 0.000 abstract 2
239000004030 hiv protease inhibitor Substances 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract 2
102000002004 Cytochrome P-450 Enzyme System Human genes 0.000 abstract 1
208000031886 HIV Infections Diseases 0.000 abstract 1
208000037357 HIV infectious disease Diseases 0.000 abstract 1
108010028554 LDL Cholesterol Proteins 0.000 abstract 1
238000008214 LDL Cholesterol Methods 0.000 abstract 1
108010007622 LDL Lipoproteins Proteins 0.000 abstract 1
101710198130 NADPH-cytochrome P450 reductase Proteins 0.000 abstract 1
230000001747 exhibiting effect Effects 0.000 abstract 1
208000033519 human immunodeficiency virus infectious disease Diseases 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Hematology (AREA)
Bioinformatics & Cheminformatics (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Diabetes (AREA)
Obesity (AREA)
Engineering & Computer Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

EEP200400065A 2001-08-31 2002-08-21 Atasanaviiri kasutamine HIV-i ravis EE200400065A (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US31674501P	2001-08-31	2001-08-31
PCT/US2002/026675 WO2003020206A2 (en)	2001-08-31	2002-08-21	Use of atazanavir in hiv therapy

Publications (1)

Publication Number	Publication Date
EE200400065A true EE200400065A (et)	2004-06-15

Family

ID=23230468

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200400065A EE200400065A (et)	2001-08-31	2002-08-21	Atasanaviiri kasutamine HIV-i ravis

Country Status (27)

Country	Link
US (1)	US20030045501A1 (et)
EP (1)	EP1420799B1 (et)
JP (1)	JP2005501880A (et)
KR (1)	KR20040029447A (et)
CN (1)	CN1245988C (et)
AT (1)	ATE341332T1 (et)
AU (1)	AU2002332610B2 (et)
BG (1)	BG108585A (et)
BR (1)	BR0211544A (et)
CA (1)	CA2458807A1 (et)
CZ (1)	CZ2004288A3 (et)
DE (1)	DE60215189T2 (et)
DK (1)	DK1420799T3 (et)
EE (1)	EE200400065A (et)
ES (1)	ES2274119T3 (et)
HR (1)	HRP20040181A2 (et)
HU (1)	HUP0401091A2 (et)
IL (1)	IL159849A0 (et)
IS (1)	IS7158A (et)
MX (1)	MXPA04001721A (et)
NO (1)	NO20040803L (et)
NZ (1)	NZ530722A (et)
PL (1)	PL367873A1 (et)
RU (1)	RU2316341C2 (et)
WO (1)	WO2003020206A2 (et)
YU (1)	YU12204A (et)
ZA (1)	ZA200401412B (et)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP4839221B2 (ja) *	2003-11-07	2011-12-21	ジェイジェイファーマ，インコーポレイテッド	Ｈｄｌを高める併用療法用複合物
US20050148523A1 (en) *	2003-12-15	2005-07-07	Colonno Richard J.	Method of treating HIV infection in atazanavir-resistant patients using a combination of atazanavir and another protease inhibitor
WO2008156632A1 (en)	2007-06-12	2008-12-24	Concert Pharmaceuticals, Inc.	Azapeptide derivatives
DE602008005896D1 (de) *	2007-06-22	2011-05-12	Bristol Myers Squibb Co	Tablettierte atazanavirhaltige zusammensetzungen
US20100178340A1 (en) *	2007-06-22	2010-07-15	Bristol-Myers Squibb Company	Tableted compositions containing atazanavir
AU2008268627A1 (en) *	2007-06-22	2008-12-31	Bristol-Myers Squibb Company	Tableted compositions containing atazanavir
SI2170292T1 (sl) *	2007-06-22	2014-05-30	Bristol-Myers Squibb Holdings Ireland	Tabletirani sestavki, ki vsebujejo atazanavir
AP3010A (en) *	2007-10-29	2014-10-31	Cipla Ltd	Novel antiretroviral combination
CN101249138B (zh) *	2008-03-28	2012-03-21	中国人民解放军军事医学科学院野战输血研究所	一种含五味子乙醇提取物的抗艾滋病药物组合物
US20130023496A1 (en) *	2010-04-02	2013-01-24	Randy Tressler	Combination Therapy Comprising A CCR5 Antagonist, A HIV-1 Protease Inhibtior and a Pharmacokinetic Enhancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2188638C2 (ru) *	1996-04-04	2002-09-10	Шионоги Энд Ко., Лтд.	Анти-вич-композиция, содержащая имидазольные производные

2002
- 2002-08-21 EE EEP200400065A patent/EE200400065A/et unknown
- 2002-08-21 HU HU0401091A patent/HUP0401091A2/hu unknown
- 2002-08-21 HR HR20040181A patent/HRP20040181A2/xx not_active Application Discontinuation
- 2002-08-21 RU RU2004106787/14A patent/RU2316341C2/ru not_active IP Right Cessation
- 2002-08-21 CZ CZ2004288A patent/CZ2004288A3/cs unknown
- 2002-08-21 AU AU2002332610A patent/AU2002332610B2/en not_active Ceased
- 2002-08-21 MX MXPA04001721A patent/MXPA04001721A/es active IP Right Grant
- 2002-08-21 PL PL02367873A patent/PL367873A1/xx not_active Application Discontinuation
- 2002-08-21 DK DK02797744T patent/DK1420799T3/da active
- 2002-08-21 JP JP2003524520A patent/JP2005501880A/ja not_active Withdrawn
- 2002-08-21 DE DE60215189T patent/DE60215189T2/de not_active Expired - Fee Related
- 2002-08-21 CN CNB028166868A patent/CN1245988C/zh not_active Expired - Fee Related
- 2002-08-21 BR BR0211544-1A patent/BR0211544A/pt not_active IP Right Cessation
- 2002-08-21 NZ NZ530722A patent/NZ530722A/en unknown
- 2002-08-21 US US10/225,754 patent/US20030045501A1/en not_active Abandoned
- 2002-08-21 ES ES02797744T patent/ES2274119T3/es not_active Expired - Lifetime
- 2002-08-21 IL IL15984902A patent/IL159849A0/xx unknown
- 2002-08-21 KR KR10-2004-7002851A patent/KR20040029447A/ko not_active Ceased
- 2002-08-21 AT AT02797744T patent/ATE341332T1/de not_active IP Right Cessation
- 2002-08-21 EP EP02797744A patent/EP1420799B1/en not_active Expired - Lifetime
- 2002-08-21 YU YU12204A patent/YU12204A/sh unknown
- 2002-08-21 CA CA002458807A patent/CA2458807A1/en not_active Abandoned
- 2002-08-21 WO PCT/US2002/026675 patent/WO2003020206A2/en not_active Ceased
2004
- 2004-02-17 BG BG108585A patent/BG108585A/bg unknown
- 2004-02-19 IS IS7158A patent/IS7158A/is unknown
- 2004-02-20 ZA ZA200401412A patent/ZA200401412B/en unknown
- 2004-02-24 NO NO20040803A patent/NO20040803L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
CZ2004288A3 (cs)	2004-12-15
PL367873A1 (en)	2005-03-07
DE60215189T2 (de)	2007-10-25
DE60215189D1 (de)	2006-11-16
WO2003020206A3 (en)	2003-10-02
AU2002332610B2 (en)	2007-11-08
DK1420799T3 (da)	2007-01-15
EP1420799A4 (en)	2004-11-24
ATE341332T1 (de)	2006-10-15
RU2316341C2 (ru)	2008-02-10
US20030045501A1 (en)	2003-03-06
EP1420799A2 (en)	2004-05-26
IS7158A (is)	2004-02-19
NO20040803L (no)	2004-02-24
YU12204A (sh)	2006-08-17
BR0211544A (pt)	2004-07-13
HUP0401091A2 (hu)	2004-08-30
HRP20040181A2 (en)	2004-08-31
JP2005501880A (ja)	2005-01-20
CA2458807A1 (en)	2003-03-13
CN1547476A (zh)	2004-11-17
HK1061640A1 (en)	2004-09-30
BG108585A (bg)	2005-04-30
ZA200401412B (en)	2005-03-18
WO2003020206A2 (en)	2003-03-13
IL159849A0 (en)	2004-06-20
ES2274119T3 (es)	2007-05-16
EP1420799B1 (en)	2006-10-04
CN1245988C (zh)	2006-03-22
KR20040029447A (ko)	2004-04-06
NZ530722A (en)	2007-11-30
MXPA04001721A (es)	2004-05-31

Legal Events

Date	Code	Title	Description
2008-12-15	HC1A	Change of owner name

Publication	Publication Date	Title
EP4445900A3 (en)	2024-10-23	Therapeutic compounds for hiv virus infection
EE200400065A (et)	2004-06-15	Atasanaviiri kasutamine HIV-i ravis
MY138732A (en)	2009-07-31	Conjugated complement cascade inhibitors
ECSP034922A (es)	2004-04-28	Pirrolopirimidinas
ATE416789T1 (de)	2008-12-15	Kombinationen für die hcv-behandlung
DK0871465T3 (da)	2003-02-03	Anvendelse af ritonavir (ABT-538) til at forbedre farmakokinetikken af lægemidler, som metaboliseres af cytochrom P450, i en metode til behandling af AIDS
DE60107065D1 (de)	2004-12-16	Behandlung des kongestiven herzversagens durch vorbehandeltes autologes blut
NO20034094L (no)	2003-09-15	Sammensetninger som omfatter et antidiar±middel og et epotilon eller et epotilonderivat
ATE534433T1 (de)	2011-12-15	Kombinierte verwendung von enzyminhibitoren zur therapie und prävention allergischer reaktionen vom typ i nach gell und coombs und zur therapie und prävention dermatologischer erkrankungen mit follikulären und epidermalen hyperkeratosen und einer verstärkten keratinozytenproliferation
EA200702242A1 (ru)	2008-02-28	Использование сульфонамидного соединения для улучшения фармакокинетики лекарственного средства
WO2003024386A8 (en)	2004-06-24	Use of potent, selective and non toxic c-kit inhibitors for treating interstitial cystitis
MX2010002909A (es)	2010-03-30	Metodo de tratamiento de pacientes de hepatitis c.
MX2022014034A (es)	2023-01-11	Métodos para tratar covid-19 con el uso de bardoxolona metilo o análogos de esta.
WO2003004006A8 (en)	2003-08-21	Use of potent, selective and non toxic c-kit inhibitors for treating tumor angiogenesis
MX2024015041A (es)	2025-04-02	Fitusiran para el tratamiento de la hemofilia a y b
MXPA05001885A (es)	2005-06-03	El uso de una combinacion de ciclesonida y antihistaminas para el tratamiento de la rinitis alergica.
RU2004106787A (ru)	2004-12-10	Применение атазанавира в терапии вич-инфекции
ZA202210111B (en)	2025-05-28	Anti-coronavirus effect and application of pi4k inhibitor
MXPA05005911A (es)	2005-08-29	Utilizacion del acido docosahexaenoico como sustancia activa para el tratamiento de la lipodistrofia.
AU4111600A (en)	2000-12-12	The use of gssg reductase for the therapy and prophylaxis of hiv infected patients
WO2022092907A3 (ko)	2022-12-08	다부위에 적용가능한 플라즈마 치료기
AU2002317877A1 (en)	2003-02-17	Use of a lactate salt for the treatment and prophylaxis of atherosclerosis
DE602005023717D1 (de)	2010-11-04	Chinolin-4-one als inhibitoren der retroviralen integrase zur behandlung von hiv, aids und aids-related complex (arc)
UA32184A (uk)	2000-12-15	Суміш для лаважу інфікованого вогнища
UA3215U (uk)	2004-10-15	Спосіб лікування пацієнтів хворих фосааксиляріозом