EE9600201A - CDCH uus kristallmodifikatsioon, selle valmistamismeetod ning seda modifikatsiooni sisaldavad farmatseutilised preparaadid - Google Patents

CDCH uus kristallmodifikatsioon, selle valmistamismeetod ning seda modifikatsiooni sisaldavad farmatseutilised preparaadid

Info

Publication number
EE9600201A
EE9600201A EE9600201A EE9600201A EE9600201A EE 9600201 A EE9600201 A EE 9600201A EE 9600201 A EE9600201 A EE 9600201A EE 9600201 A EE9600201 A EE 9600201A EE 9600201 A EE9600201 A EE 9600201A
Authority
EE
Estonia
Prior art keywords
modification
cdch
preparation
pharmaceutical preparations
preparations containing
Prior art date
Application number
EE9600201A
Other languages
English (en)
Other versions
EE03474B1 (et
Inventor
Grunenberg Alfons
Bosche Patrick
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7779831&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE9600201(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of EE9600201A publication Critical patent/EE9600201A/et
Publication of EE03474B1 publication Critical patent/EE03474B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EE9600201A 1995-12-12 1996-12-11 CDCH kristallimodifikatsioon, selle valmistamismeetod ning seda modifikatsiooni sisaldavad farmatseutilised preparaadid EE03474B1 (et)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19546249A DE19546249A1 (de) 1995-12-12 1995-12-12 Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen

Publications (2)

Publication Number Publication Date
EE9600201A true EE9600201A (et) 1997-06-16
EE03474B1 EE03474B1 (et) 2001-08-15

Family

ID=7779831

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9600201A EE03474B1 (et) 1995-12-12 1996-12-11 CDCH kristallimodifikatsioon, selle valmistamismeetod ning seda modifikatsiooni sisaldavad farmatseutilised preparaadid

Country Status (42)

Country Link
US (1) US5849752A (et)
EP (1) EP0780390B1 (et)
JP (1) JP4104687B2 (et)
KR (1) KR100525146B1 (et)
CN (1) CN1061348C (et)
AR (1) AR005009A1 (et)
AT (1) ATE221531T1 (et)
AU (1) AU708006B2 (et)
BG (1) BG62258B1 (et)
BR (1) BR9605968A (et)
CA (1) CA2192418C (et)
CO (1) CO4480105A1 (et)
CU (1) CU22774A3 (et)
CZ (1) CZ288657B6 (et)
DE (2) DE19546249A1 (et)
DK (1) DK0780390T3 (et)
EE (1) EE03474B1 (et)
ES (1) ES2179910T3 (et)
HR (1) HRP960558B1 (et)
HU (1) HU226521B1 (et)
ID (1) ID22625A (et)
IL (1) IL119795A (et)
IN (1) IN185805B (et)
MA (1) MA24342A1 (et)
MY (1) MY117492A (et)
NL (1) NL300109I1 (et)
NO (1) NO306725B1 (et)
NZ (1) NZ299905A (et)
PL (1) PL184885B1 (et)
PT (1) PT780390E (et)
RO (1) RO119782B1 (et)
RU (1) RU2162468C2 (et)
SA (1) SA96170492B1 (et)
SG (1) SG47201A1 (et)
SI (1) SI0780390T1 (et)
SK (1) SK282805B6 (et)
SV (1) SV1996000109A (et)
TR (1) TR199600970A2 (et)
TW (1) TW411340B (et)
UA (1) UA35638C2 (et)
YU (1) YU49485B (et)
ZA (1) ZA9610405B (et)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999015172A1 (de) 1997-09-25 1999-04-01 Bayer Aktiengesellschaft Arzneimittelformulierung mit kontrollierter wirkstofffreisetzung
DE19751948A1 (de) * 1997-11-24 1999-05-27 Bayer Ag Verfahren zur Herstellung von 8-Methoxy-Chinoloncarbonsäuren
US6509327B1 (en) 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
US6395746B1 (en) 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
US6716830B2 (en) * 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
ATE279193T1 (de) * 1998-11-10 2004-10-15 Bayer Healthcare Ag Pharmazeutische zubereitung von moxifloxacin
DE19854355A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854356A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854357A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908449A1 (de) * 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
AU2003278418A1 (en) * 2002-10-31 2004-05-25 Ranbaxy Laboratories Limited Amorphous moxifloxacin hydrochloride
CA2521398C (en) * 2003-04-09 2011-03-22 Dr. Reddy's Laboratories Limited A crystalline form iii of anhydrous moxifloxacin hydrochloride and a process for preparation thereof
WO2005012285A1 (en) * 2003-08-05 2005-02-10 Matrix Laboratories Ltd An improved process for the preparation of moxifloxacin hydrochloride
ITMI20032259A1 (it) 2003-11-20 2005-05-21 Chemi Spa Nuovo polimorfo dell'acido 1-ciclopropil-7-(s,s-2,8-diazabciclo-4.3.0-non-8-il)-6-fluoro-1,4-diidro-8-metossi-4-oxo-chinolin carbossilico cloridrato e metodi per la sua preparazione
EP1685130B1 (en) * 2003-11-20 2008-12-10 CHEMI S.p.A. Polymorphs of 1-cyclopropyl-7-([s,s] - 2,8-diazadicyclo [4.3.0] non-8-yl) -6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinoline carboxylic acid hydrochloride and methods for the preparation thereof
US7491725B2 (en) 2004-02-06 2009-02-17 Bristol-Myers Squibb Company Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors
DE102004015981A1 (de) * 2004-04-01 2005-10-20 Bayer Healthcare Ag Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE102004063347A1 (de) * 2004-12-23 2006-07-13 Stada Arzneimittel Ag Gebrauchsfertige Gemcitabinlösungen und Gemcitabinlösungskonzentrate
WO2007033515A1 (fr) * 2005-09-21 2007-03-29 Shenzhen Tys R & D Co., Ltd. Formulation orale contenant de la moxifloxacine et son procédé de préparation
GB0612422D0 (en) * 2006-06-23 2006-08-02 Generics Uk Ltd Novel hydrate form
PL2032521T3 (pl) 2006-06-27 2010-05-31 Sandoz Ag Nowy sposób wytwarzania soli
ES2303768B1 (es) * 2006-09-08 2009-06-05 Quimica Sintetica, S.A. Nueva forma cristalina de moxifloxacino clorhidrato.
NZ576929A (en) * 2006-11-13 2012-07-27 Cipla Ltd Crystalline anhydrous form C of moxifloxacin hydrochloride
EP1992626A1 (en) * 2007-05-10 2008-11-19 Sandoz AG Process for the preparation of moxifloxacin hydrochloride
EP2083010A1 (en) * 2008-01-08 2009-07-29 Chemo Ibérica, S.A. Polymorphic Forms of Moxifloxacin hydrochloride and processes for preparation thereof
EP2154137A1 (en) 2008-08-04 2010-02-17 Chemo Ibérica, S.A. Crystalline form of moxifloxacin base
CN102176902B (zh) 2008-10-09 2012-10-31 阿卜迪易卜拉欣贸易公司 有机溶剂在莫西沙星湿法造粒中的应用
WO2010052726A1 (en) * 2008-11-06 2010-05-14 Hetero Research Foundation Novel polymorph of moxifloxacin hydrochloride
US20110293717A1 (en) 2008-12-08 2011-12-01 Ratiopharm Gmbh Compacted moxifloxacin
CA2762022A1 (en) 2009-05-15 2010-11-18 Redx Pharma Limited Redox drug derivatives
WO2011121596A2 (en) * 2010-04-01 2011-10-06 Neuland Laboratories Ltd. Crystal modification of moxifloxacin hydrochloride
BRPI1106900A2 (pt) 2011-12-26 2013-11-05 Ems Sa Composição farmacêutica sólida compreendendo antibótico da familia das quinolonas e processo de sua obtenção
FR2992218B1 (fr) 2012-06-22 2015-01-23 Rivopharm Sa Composition pharmaceutique de chlorhydrate de moxifloxacine et procede de preparation
CN102924449B (zh) * 2012-10-30 2015-08-12 重庆福安药业集团庆余堂制药有限公司 盐酸莫西沙星h晶型及其制备方法和药物组合物
CA2893534A1 (en) 2012-12-04 2014-06-12 Mankind Research Centre An improved process for the preparation of moxifloxacin hydrochloride
RU2561037C2 (ru) * 2013-02-07 2015-08-20 Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") Антибактериальная фармацевтическая композиция и способ ее получения
CA2904387C (en) 2013-03-15 2021-12-07 Melinta Therapeutics, Inc. Methods of treating infections in overweight and obese patients using antibiotics

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3601567A1 (de) * 1986-01-21 1987-07-23 Bayer Ag 7-(azabicycloalkyl)-chinoloncarbonsaeure- und -naphthyridon-carbonsaeure-derivate
FI871419L (fi) * 1986-03-31 1987-10-01 Sankyo Co Kinolin-3-karboxylsyraderivat, deras framstaellning och anvaendning.
AU609974B2 (en) * 1988-05-18 1991-05-09 Warner-Lambert Company Improved process for the preparation of 5-amino-7- (substituted amino)-quinoline-3-carboxylic acids
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
RO108347B1 (ro) * 1989-10-30 1994-04-28 Bellon Labor Sa Roger DERIVATI DE BENZO-(b)-NAFTIRIDIN-1,8 SI PROCEDEU DE PREPARARE A ACESTORA
TW209865B (et) 1992-01-10 1993-07-21 Bayer Ag
KR100228572B1 (ko) * 1992-01-31 1999-11-01 이병언 퀴놀론카르복실산 유도체 수화물 결정
DE4234078A1 (de) 1992-10-09 1994-04-14 Bayer Ag Chinoloncarbonsäuren
JP3268098B2 (ja) * 1992-12-25 2002-03-25 第一製薬株式会社 二環性環状アミン誘導体
ZA946853B (en) * 1993-09-10 1995-04-24 Daiichi Seiyaku Co Crystals of antimicrobial compound.
DK0676199T3 (da) * 1994-04-07 1999-02-08 Pfizer Anvendelse af trovafloxacin eller derivater deraf til fremstilling af et medikament til behandling af H. pylori-infektione

Also Published As

Publication number Publication date
CU22774A3 (es) 2002-07-24
NO965298L (no) 1997-06-13
DE59609501D1 (de) 2002-09-05
SK282805B6 (sk) 2002-12-03
NZ299905A (en) 1998-09-24
BG101043A (en) 1998-04-30
HUP9603428A3 (en) 1997-10-28
NO306725B1 (no) 1999-12-13
CA2192418C (en) 2001-06-12
DK0780390T3 (da) 2002-11-11
ID22625A (id) 1999-12-02
CN1061348C (zh) 2001-01-31
TR199600970A2 (tr) 1997-06-21
EE03474B1 (et) 2001-08-15
NO965298D0 (no) 1996-12-11
HRP960558B1 (en) 2002-04-30
JPH09169757A (ja) 1997-06-30
HU9603428D0 (en) 1997-01-28
US5849752A (en) 1998-12-15
DE19546249A1 (de) 1997-06-19
CZ288657B6 (cs) 2001-08-15
AR005009A1 (es) 1999-04-07
CO4480105A1 (es) 1997-07-09
BR9605968A (pt) 1998-08-18
IN185805B (et) 2001-05-05
SI0780390T1 (en) 2002-10-31
CZ364696A3 (en) 1997-07-16
RO119782B1 (ro) 2005-03-30
AU708006B2 (en) 1999-07-29
EP0780390B1 (de) 2002-07-31
PL184885B1 (pl) 2003-01-31
SA96170492B1 (ar) 2006-05-23
BG62258B1 (bg) 1999-06-30
SV1996000109A (es) 1997-10-23
TW411340B (en) 2000-11-11
CA2192418A1 (en) 1997-06-13
AU7421696A (en) 1997-06-19
HUP9603428A2 (en) 1997-08-28
CN1160052A (zh) 1997-09-24
PL317415A1 (en) 1997-06-23
IL119795A0 (en) 1997-03-18
ATE221531T1 (de) 2002-08-15
YU65096A (sh) 1998-12-23
MX9606325A (es) 1997-10-31
MA24342A1 (fr) 1998-07-01
ZA9610405B (en) 1997-06-23
EP0780390A1 (de) 1997-06-25
JP4104687B2 (ja) 2008-06-18
SK159196A3 (en) 1997-10-08
KR970042550A (ko) 1997-07-24
UA35638C2 (uk) 2001-04-16
RU2162468C2 (ru) 2001-01-27
HU226521B1 (en) 2009-03-30
PT780390E (pt) 2002-11-29
IL119795A (en) 1998-12-27
ES2179910T3 (es) 2003-02-01
YU49485B (sh) 2006-08-17
HRP960558A2 (en) 1998-02-28
MY117492A (en) 2004-07-31
NL300109I1 (nl) 2003-02-03
SG47201A1 (en) 1998-03-20
KR100525146B1 (ko) 2006-01-27

Similar Documents

Publication Publication Date Title
EE03474B1 (et) CDCH kristallimodifikatsioon, selle valmistamismeetod ning seda modifikatsiooni sisaldavad farmatseutilised preparaadid
NO20002835L (no) 2-aryl-oksodihydropurinderivater, fremgangsmÕte for fremstilling av disse medisinske preparater inneholdende disse, og mellomprodukter derfor
EE200000317A (et) Ühend, seda sisaldav farmatseutiline kompositsioon, keemiline ühend ja meetod nende valmistamiseks
FR2707882B1 (fr) Nouveaux kits thérapeutiques anti-médiateurs protéiques, procédé de préparation et compositions pharmaceutiques les renfermant.
ATE402187T1 (de) Abgewandelte aminosäuren, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
NO975987D0 (no) 4-Fenylaminotiazol-derivater, fremgangsmåte for fremstilling av disse og farmasöytiske blandinger inneholdende nevnte derivater
CZ129596A3 (en) Oxazolidinone derivative, process of its preparation and pharmaceutical composition containing thereof
EE03489B1 (et) Olansapiini polümorfne vorm II, selle saamismeetod ja farmatseutiline preparaat
NO973479L (no) Substituerte heterosykliske forbindelser, fremgangsmåte for fremstilling og farmasöytiske blandinger inneholdende samme
HUP0000214A3 (en) Alpha-substituted benzenesulphonamido hydroxamic acids, process for their preparation and pharmaceutical compositions containing them
FI922620A7 (fi) Peptidijohdannainen, menetelmä sen valmistamiseksi, sitä sisältävä far maseuttinen valmiste ja menetelmä glaukooman hoitamiseksi
NO305903B1 (no) Benzonitriler og benzofluorider, legemidler bestående av forbindelsene, farmasöytiske preparater inneholdende forbindelsene, samt anvendelse av forbindelsene for fremstilling av farmasöytiske preparater
EE9600183A (et) Kristalne (R)-(-)-2-{N-[4-(1,1-dioksido-3-okso-2,3-dihüdrobensisotiasool-2-üül) butüül ] aminometüül }kromaanhüdrokloriid, selle valmistamismeetod, kasutamine ravimite valmistamiseks ja ravimid
AU6611396A (en) New oxazolidinone derivatives, processes for the production thereof and pharmaceutical agents containing these compounds
EE03353B1 (et) Kristalne 5-atseetamido-2,3,4,5-tetradesoksü-4-guanidino-D-glütsero-D-galaktonon-2-eenpüranosoonh ape, selle valmistamismeetod ja seda sisaldavad farmatseutilised preparaadid
AU8087087A (en) Process for the preparation of 5,6 dihydroxyindole and its 3-alkyl derivative; intermediate compounds and its nitrile intermediate compounds
EE200200199A (et) N-guanidinoalküülamiid, meetod selle valmistamiseks, seda sisaldav farmatseutiline preparaat ning raviotstarbeline kasutamine
EE200100662A (et) Hüübimistegurit pärssiv ühend, meetod selle valmistamiseks, seda sisaldav farmatseutiline preparaatning raviotstarbeline kasutamine
DZ2510A1 (fr) Composition comprenant de la 5-Ä4-Ä2-(n-méthyl-n-(2-pyridyl)amino)éthoxyÜbenzylÜthiazolidine-2,4-dione et procédé pour sa préparation.
AU5103196A (en) Form of administration for applying pharmaceutical substances and auxiliary substances, and process for the preparation thereof
EE9600109A (et) a-amino- ja tsüklopentaan-ß-aminohapet(-happeid) ja/või nende derivaate sisaldavad segud ja dipeptiidid, dipeptiidide valmistamismeetod ning nimetatud segusid ja/või dipeptiide sisaldavad ravimid
FI955238A7 (fi) Uudet 5-(aryylioksimetyyli)oksatsoliinit, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset
DK1100775T3 (da) 2,5-Substituerede benzensulfonylurinstoffer og -thiourinstoffer, fremgangsmåde til fremstilling deraf, anvendelse deraf og farmaceutiske præparater indeholdende disse
FI960284L (fi) Uudet merkaptoalkanoyylidipeptidiyhdisteet, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset
KR950703559A (ko) 신규한 축합 티아졸 유도체, 이의 제조방법 및 이를 함유하는 약제학적 조성물(Novel condensed thiazole derivative, process for producing the same, and pharmaceutical composition containing the same)

Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20021231

KB4A Valid patent at the end of a year

Effective date: 20031231

GB1A Change in the ownership or in the address of the owner
KB4A Valid patent at the end of a year

Effective date: 20041231

KB4A Valid patent at the end of a year

Effective date: 20051231

KB4A Valid patent at the end of a year

Effective date: 20061231

KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

GB1A Change in the ownership or in the address of the owner
KB4A Valid patent at the end of a year

Effective date: 20091231

KB4A Valid patent at the end of a year

Effective date: 20101231