EE9700166A - Melatoniini kasutamine ravimi tootmiseks - Google Patents

Melatoniini kasutamine ravimi tootmiseks

Info

Publication number: EE9700166A
Authority: EE; Estonia
Prior art keywords: melatonin; manufacture; medicinal product; medicinal; product
Prior art date: 1995-02-01

Application number

EE9700166A

Other languages

English (en)

Other versions

EE03384B1 (et

Inventor

Zisapel Nava

Original Assignee

Neurim Pharmaceuticals (1991) Ltd.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-02-01

Filing date

1996-01-29

Publication date

1998-02-16

1995-02-01 Priority claimed from US08/381,535 external-priority patent/US6469044B1/en

1996-01-29 Application filed by Neurim Pharmaceuticals (1991) Ltd. filed Critical Neurim Pharmaceuticals (1991) Ltd.

1998-02-16 Publication of EE9700166A publication Critical patent/EE9700166A/et

2001-04-16 Publication of EE03384B1 publication Critical patent/EE03384B1/et

Links

YJPIGAIKUZMOQA-UHFFFAOYSA-N Melatonin Natural products COC1=CC=C2N(C(C)=O)C=C(CCN)C2=C1 YJPIGAIKUZMOQA-UHFFFAOYSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
229940126601 medicinal product Drugs 0.000 title 1
DRLFMBDRBRZALE-UHFFFAOYSA-N melatonin Chemical compound COC1=CC=C2NC=C(CCNC(C)=O)C2=C1 DRLFMBDRBRZALE-UHFFFAOYSA-N 0.000 title 1
229960003987 melatonin Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Addiction (AREA)
Psychiatry (AREA)
Toxicology (AREA)
Anesthesiology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

EE9700166A 1995-02-01 1996-01-29 Melatoniini kasutamine ravimi tootmiseks EE03384B1 (et)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US08/381,535 US6469044B1 (en)	1995-02-01	1995-02-01	Method for treating patients suffering from drug dependencies which lead to plasma melationin deficiencies
EP95303853A EP0724878B1 (en)	1995-02-01	1995-06-06	Use of melatonin for treating patients suffering from drug dependencies
PCT/IB1996/000082 WO1996023496A1 (en)	1995-02-01	1996-01-29	Use of melatonin for treating patients suffering from drug addiction

Publications (2)

Publication Number	Publication Date
EE9700166A true EE9700166A (et)	1998-02-16
EE03384B1 EE03384B1 (et)	2001-04-16

Family

ID=26140195

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EE9700166A EE03384B1 (et)	1995-02-01	1996-01-29	Melatoniini kasutamine ravimi tootmiseks

Country Status (22)

Country	Link
JP (1)	JP4516159B2 (et)
CN (1)	CN1083263C (et)
AT (1)	AT408188B (et)
AU (1)	AU695366B2 (et)
BG (1)	BG62876B1 (et)
BR (1)	BR9607169A (et)
CZ (1)	CZ291349B6 (et)
DK (1)	DK176081B1 (et)
EE (1)	EE03384B1 (et)
FI (1)	FI119586B (et)
IS (1)	IS1980B (et)
LU (1)	LU90118B1 (et)
LV (1)	LV11940B (et)
MD (1)	MD1716C2 (et)
NO (1)	NO312814B1 (et)
NZ (1)	NZ298878A (et)
PL (1)	PL183148B1 (et)
SI (1)	SI9620022A (et)
SK (1)	SK284521B6 (et)
TR (1)	TR199700723T1 (et)
TW (1)	TW483757B (et)
WO (1)	WO1996023496A1 (et)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MXPA02005783A (es)	2000-01-05	2003-10-14	Neurim Pharma 1991	Metodo y formulacion para el tratamiento de la resistencia a los antihipertensivos y otras afecciones asociadas.
IL149377A (en) *	2002-04-28	2012-10-31	Neurim Pharma 1991	Pharmaceutical formulation comprising melatonin for the potentiation of the effect of hypnotic compounds
IL155666A (en)	2003-04-29	2013-12-31	Neurim Pharma 1991	Insomnia treatment
US9119846B2 (en)	2003-04-29	2015-09-01	Neurim Pharmaceuticals (1991) Ltd.	Method and composition for enhancing cognition in alzheimer's patients
WO2013112951A2 (en)	2012-01-26	2013-08-01	Vanda Pharmaceuticals Inc.	Treatment of circadian rhythm disorders
US11918557B2 (en)	2012-01-26	2024-03-05	Vanda Pharmaceuticals Inc.	Treatment of circadian rhythm disorders
KR102148990B1 (ko)	2012-12-18	2020-08-27	반다 파마슈티칼즈, 인코퍼레이티드.	일주기 리듬 장애의 치료
US10376487B2 (en)	2013-11-12	2019-08-13	Vanda Pharmaceuticals Inc.	Method of treatment
US11090285B2 (en)	2013-11-12	2021-08-17	Vanda Pharmaceuticals Inc	Treatment of circadian rhythm disorders
JP6830156B2 (ja) *	2016-10-31	2021-02-17	ニューリム・ファーマシューティカルズ・リミテッドＮｅｕｒｉｍＰｈａｒｍａｃｅｕｔｉｃａｌｓＬｔｄ．	メラトニンミニタブレットおよびその製造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2134789T3 (es) *	1991-05-09	1999-10-16	Neurim Pharma 1991	Composiciones que contienen melatonina.
IT1251544B (it) *	1991-05-13	1995-05-17	Gabriele Biella	Composizioni farmaceutiche attive nella terapia dei disturbi del sonno comprendenti melatonina o un suo derivato in associazione con un derivato benzodiazepinico

1996
- 1996-01-29 MD MD97-0254A patent/MD1716C2/ro not_active IP Right Cessation
- 1996-01-29 EE EE9700166A patent/EE03384B1/et not_active IP Right Cessation
- 1996-01-29 BR BR9607169A patent/BR9607169A/pt not_active Application Discontinuation
- 1996-01-29 SK SK1030-97A patent/SK284521B6/sk unknown
- 1996-01-29 TR TR97/00723T patent/TR199700723T1/xx unknown
- 1996-01-29 PL PL96321630A patent/PL183148B1/pl unknown
- 1996-01-29 AT AT0901396A patent/AT408188B/de not_active IP Right Cessation
- 1996-01-29 SI SI9620022A patent/SI9620022A/sl not_active IP Right Cessation
- 1996-01-29 NZ NZ298878A patent/NZ298878A/xx not_active IP Right Cessation
- 1996-01-29 CZ CZ19972405A patent/CZ291349B6/cs not_active IP Right Cessation
- 1996-01-29 WO PCT/IB1996/000082 patent/WO1996023496A1/en not_active Ceased
- 1996-01-29 CN CN96191750A patent/CN1083263C/zh not_active Expired - Lifetime
- 1996-01-29 JP JP52338596A patent/JP4516159B2/ja not_active Expired - Lifetime
- 1996-01-29 AU AU44574/96A patent/AU695366B2/en not_active Expired
- 1996-04-12 TW TW085104319A patent/TW483757B/zh not_active IP Right Cessation
1997
- 1997-07-24 LV LVP-97-144A patent/LV11940B/en unknown
- 1997-07-25 IS IS4532A patent/IS1980B/is unknown
- 1997-07-30 BG BG101803A patent/BG62876B1/bg unknown
- 1997-07-30 DK DK199700896A patent/DK176081B1/da not_active IP Right Cessation
- 1997-07-31 FI FI973185A patent/FI119586B/fi not_active IP Right Cessation
- 1997-07-31 NO NO19973531A patent/NO312814B1/no not_active IP Right Cessation
- 1997-08-01 LU LU90118A patent/LU90118B1/fr active

Also Published As

Publication number	Publication date
IS1980B (is)	2005-01-14
AT408188B (de)	2001-09-25
TW483757B (en)	2002-04-21
AU695366B2 (en)	1998-08-13
CZ291349B6 (cs)	2003-02-12
LU90118B1 (fr)	1997-11-13
FI973185L (fi)	1997-09-30
MD1716C2 (ro)	2002-02-28
FI973185A0 (fi)	1997-07-31
CN1083263C (zh)	2002-04-24
BG62876B1 (bg)	2000-10-31
MD970254A (en)	1999-05-31
AU4457496A (en)	1996-08-21
BG101803A (en)	1998-04-30
JP4516159B2 (ja)	2010-08-04
NZ298878A (en)	1999-05-28
JPH10513177A (ja)	1998-12-15
DK176081B1 (da)	2006-04-18
WO1996023496A1 (en)	1996-08-08
DK89697A (da)	1997-07-30
FI119586B (fi)	2009-01-15
CN1172431A (zh)	1998-02-04
TR199700723T1 (xx)	1998-02-21
CZ240597A3 (cs)	1998-01-14
IS4532A (is)	1997-07-25
SK284521B6 (sk)	2005-05-05
MX9705856A (es)	1998-07-31
SI9620022A (sl)	1998-10-31
NO973531D0 (no)	1997-07-31
NO973531L (no)	1997-09-30
EE03384B1 (et)	2001-04-16
PL321630A1 (en)	1997-12-08
BR9607169A (pt)	1997-11-11
MD1716B2 (en)	2001-08-31
SK103097A3 (en)	1998-01-14
LV11940B (en)	1998-05-20
ATA901396A (de)	2001-02-15
PL183148B1 (pl)	2002-05-31
LV11940A (lv)	1998-01-20
NO312814B1 (no)	2002-07-08

Legal Events

Date	Code	Title	Description
2003-02-17	KB4A	Valid patent at the end of a year	Effective date: 20021231
2004-02-16	KB4A	Valid patent at the end of a year	Effective date: 20031231
2005-02-15	KB4A	Valid patent at the end of a year	Effective date: 20041231
2006-02-15	KB4A	Valid patent at the end of a year	Effective date: 20051231
2007-02-15	KB4A	Valid patent at the end of a year	Effective date: 20061231
2007-10-15	MM4A	Lapsed by not paying the annual fees	Effective date: 20070129

Publication	Publication Date	Title
ATE248594T1 (de)	2003-09-15	Irbesartanhaltiges arzneimittel
FI954402A0 (fi)	1995-09-18	Uusi farmaseuttinen tuote
HRP960365B1 (en)	2002-04-30	New medicaments and the use thereof
FI956227L (fi)	1995-12-22	Sisäänhengitykseen tarkoitettu terapeuttinen valmiste
DE69632756D1 (de)	2004-07-29	Hautpflegemittel
IL111380A0 (en)	1994-12-29	Potentiation of drug response
DE69523440D1 (de)	2001-11-29	Mundpflegemittel
ZA963413B (en)	1996-11-06	Use of retinoids in a cosmetic composition or for the manufacture of a pharmaceutical composition
DE69516453D1 (de)	2000-05-31	Hautpflegemittel
EP0823255A4 (en)	1999-01-27	Pharmaceutical composition containing sucralfate
DE69521692D1 (de)	2001-08-16	Mundpflegemittel
ITMI940884A0 (it)	1994-05-06	Medicamento topico ad attivita' cicatrizzante
EE9700166A (et)	1998-02-16	Melatoniini kasutamine ravimi tootmiseks
DK86492D0 (da)	1992-06-30	Laegemiddel
LV12067A (lv)	1998-06-20	17B-N-vienaizvietota-karbamoil-4-aza-5alfa-androst-1-en-3-onu pielietojums medikamenta razosanai
DE59610423D1 (de)	2003-06-12	Partikulare arzneiform
FI942803A7 (fi)	1994-12-16	Ipsapironi-lääkevalmiste
NO962385L (no)	1996-12-09	Terapeutiske amider
EP0790829A4 (en)	2001-08-08	Medicaments
ZA948357B (en)	1996-04-24	Potentiation of drug response
UA25976C2 (uk)	1999-02-26	Противиразковий лікарський препарат
SK1062U (sk)	1996-01-10	Obkladový liečebný prostriedok
DE69315324D1 (de)	1998-01-02	Mundpflegemittel
ID15808A (id)	1997-08-07	Penggunaan protease dibidang kedokteran
ATE239508T1 (de)	2003-05-15	Partikulare arzneiform