EE9900031A - Tramadooli mitmikühikulised preparaadid - Google Patents

Tramadooli mitmikühikulised preparaadid

Info

Publication number
EE9900031A
EE9900031A EEP199900031A EE9900031A EE9900031A EE 9900031 A EE9900031 A EE 9900031A EE P199900031 A EEP199900031 A EE P199900031A EE 9900031 A EE9900031 A EE 9900031A EE 9900031 A EE9900031 A EE 9900031A
Authority
EE
Estonia
Prior art keywords
tramadol
multiple unit
unit formulations
formulations
unit
Prior art date
Application number
EEP199900031A
Other languages
English (en)
Other versions
EE03742B1 (et
Inventor
Momberger Helmut
Raber Marc
Kuhn Dieter
Schmid Wolfgang
Original Assignee
Asta Medica Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Aktiengesellschaft filed Critical Asta Medica Aktiengesellschaft
Publication of EE9900031A publication Critical patent/EE9900031A/et
Publication of EE03742B1 publication Critical patent/EE03742B1/et

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Glanulating (AREA)
EEP199900031A 1996-07-25 1997-07-19 Tramadooli mitmikühikulised preparaadid ja nende valmistamismeetod EE03742B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19630035A DE19630035A1 (de) 1996-07-25 1996-07-25 Tramadol Multiple Unit Formulierungen
PCT/EP1997/003934 WO1998004249A2 (de) 1996-07-25 1997-07-19 Tramadol multiple unit formulierungen

Publications (2)

Publication Number Publication Date
EE9900031A true EE9900031A (et) 1999-08-16
EE03742B1 EE03742B1 (et) 2002-06-17

Family

ID=7800815

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP199900031A EE03742B1 (et) 1996-07-25 1997-07-19 Tramadooli mitmikühikulised preparaadid ja nende valmistamismeetod

Country Status (28)

Country Link
US (2) US5955104A (et)
EP (1) EP0917463B1 (et)
JP (1) JP3631762B2 (et)
KR (1) KR100474793B1 (et)
CN (1) CN1111402C (et)
AR (1) AR008002A1 (et)
AT (1) ATE213408T1 (et)
AU (1) AU737121B2 (et)
BG (1) BG63708B1 (et)
BR (1) BR9710761A (et)
CA (1) CA2211284C (et)
CZ (1) CZ296964B6 (et)
DE (2) DE19630035A1 (et)
DK (1) DK0917463T3 (et)
EE (1) EE03742B1 (et)
ES (1) ES2171268T3 (et)
HU (1) HU227971B1 (et)
IL (1) IL127915A (et)
NO (1) NO324207B1 (et)
NZ (1) NZ333822A (et)
PL (1) PL188834B1 (et)
PT (1) PT917463E (et)
RU (1) RU2201223C2 (et)
SK (1) SK285300B6 (et)
TW (1) TW495363B (et)
UA (1) UA52679C2 (et)
WO (1) WO1998004249A2 (et)
ZA (1) ZA975408B (et)

Families Citing this family (59)

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DE19630035A1 (de) * 1996-07-25 1998-01-29 Asta Medica Ag Tramadol Multiple Unit Formulierungen
US6197347B1 (en) * 1998-06-29 2001-03-06 Andrx Pharmaceuticals, Inc. Oral dosage for the controlled release of analgesic
US6312728B1 (en) * 1998-07-07 2001-11-06 Cascade Development, Inc. Sustained release pharmaceutical preparation
DE19901687B4 (de) * 1999-01-18 2006-06-01 Grünenthal GmbH Opioide Analgetika mit kontrollierter Wirkstofffreisetzung
DE19901686A1 (de) * 1999-01-18 2000-07-20 Gruenenthal Gmbh Retardierte Tramadolzubereitungen mit einem lagerstabilen Freisetzungsprofil und Verfahren zu deren Herstellung
AU781058B2 (en) * 1999-08-31 2005-05-05 Grunenthal Gmbh Delayed-action form of administration containing tramadol saccharinate
DE19940944B4 (de) * 1999-08-31 2006-10-12 Grünenthal GmbH Retardierte, orale, pharmazeutische Darreichungsformen
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
AU764453B2 (en) 1999-10-29 2003-08-21 Euro-Celtique S.A. Controlled release hydrocodone formulations
AR030557A1 (es) * 2000-04-14 2003-08-27 Jagotec Ag Una tableta en multicapa de liberacion controlada y metodo de tratamiento
US6620431B1 (en) 2000-04-17 2003-09-16 Charles Signorino Shellac film coatings providing release at selected pH and method
US20030157247A1 (en) * 2000-06-14 2003-08-21 Yoshiro Chikami Method for producing coated bioactive granule
EP1296666A2 (en) * 2000-07-06 2003-04-02 Delsys Pharmaceutical Corporation Improved thyroid hormone formulations
MXPA03003895A (es) 2000-10-30 2003-07-28 Euro Celtique Sa Formulaciones de hidrocodona de liberacion controlada.
RU2174836C1 (ru) * 2000-12-15 2001-10-20 Открытое акционерное общество "Химико-фармацевтический комбинат "Акрихин" Фармацевтическая композиция, обладающая анальгезирующим действием
DE10108122A1 (de) 2001-02-21 2002-10-02 Gruenenthal Gmbh Arzneimittel auf Basis von Tramadol
WO2003009805A2 (en) * 2001-07-23 2003-02-06 Brigham And Women's Hospital, Inc. Analgesic methods using endothelin receptor ligands
PE20030527A1 (es) * 2001-10-24 2003-07-26 Gruenenthal Chemie Formulacion farmaceutica con liberacion retardada que contiene 3-(3-dimetilamino-1-etil-2-metil-propil) fenol o una sal farmaceuticamente aceptable del mismo y tabletas para administracion oral que la contienen
US20050182056A9 (en) * 2002-02-21 2005-08-18 Seth Pawan Modified release formulations of at least one form of tramadol
US8128957B1 (en) * 2002-02-21 2012-03-06 Valeant International (Barbados) Srl Modified release compositions of at least one form of tramadol
CA2476201C (en) * 2002-02-21 2009-09-01 Biovail Laboratories Incorporated Modified release formulations of at least one form of tramadol
DK1894562T3 (da) * 2002-08-15 2011-03-28 Euro Celtique Sa Farmaceutiske sammensætninger omfattende en opioidantagonist
ES2269591T3 (es) * 2002-11-27 2007-04-01 ORAMON-ARZNEIMITTEL GMBH & CO. KG Procedimiento para la fabricacion de granulados que contienen un antidepresivo triciclico o tetraciclico, asi como preparaciones farmaceuticas que contienen estos granulados.
JP2006516969A (ja) * 2003-01-23 2006-07-13 アモレパシフィック コーポレーション 徐放性製剤及びその製造方法
RU2223757C1 (ru) * 2003-03-04 2004-02-20 Закрытое акционерное общество "Брынцалов-А" Препарат, обладающий анальгезирующим действием
US20040202717A1 (en) 2003-04-08 2004-10-14 Mehta Atul M. Abuse-resistant oral dosage forms and method of use thereof
US20050053669A1 (en) * 2003-09-05 2005-03-10 Boehringer Ingelheim International Gmbh Administration form for the oral application of poorly soluble acidic and amphorteric drugs
DE10341414A1 (de) * 2003-09-05 2005-03-31 Boehringer Ingelheim Pharma Gmbh & Co. Kg Oral zu applizierende Darreichungsform für schwerlösliche saure und amphotere Wirkstoffe
CA2874604A1 (en) * 2003-10-03 2005-04-21 Elite Laboratories Inc. Extended release formulations of opioids and method of use thereof
US8163114B2 (en) * 2004-04-07 2012-04-24 New Jersey Institute Of Technology Netshape manufacturing processes and compositions
US20070224281A1 (en) * 2004-07-22 2007-09-27 Amorepacific Corporation Sustained-Release Preparations Containing Topiramate and the Producing Method Thereof
CN101010072A (zh) 2004-09-01 2007-08-01 欧洲凯尔特公司 具有与剂量成比例的稳态Cave和AUC并且小于与剂量成比例的单剂量CMAX的阿片类物质剂量形式
JP2008525313A (ja) 2004-12-27 2008-07-17 エーザイ・アール・アンド・ディー・マネジメント株式会社 抗痴呆薬の安定化方法
US20070129402A1 (en) * 2004-12-27 2007-06-07 Eisai Research Institute Sustained release formulations
US20060246003A1 (en) * 2004-12-27 2006-11-02 Eisai Co. Ltd. Composition containing anti-dementia drug
EP1915137B8 (de) * 2005-08-10 2013-09-11 ADD Advanced Drug Delivery Technologies, Ltd. Orales präparat mit kontrollierter freisetzung
EP2289497A1 (en) * 2005-11-10 2011-03-02 Circ Pharma Research and Development Limited Once-daily administration of central nervous system drugs
US20070185145A1 (en) * 2006-02-03 2007-08-09 Royds Robert B Pharmaceutical composition containing a central opioid agonist, a central opioid antagonist, and a peripheral opioid antagonist, and method for making the same
US20070264346A1 (en) * 2006-02-16 2007-11-15 Flamel Technologies Multimicroparticulate pharmaceutical forms for oral administration
US20070190141A1 (en) * 2006-02-16 2007-08-16 Aaron Dely Extended release opiate composition
US20070264335A1 (en) * 2006-05-09 2007-11-15 Sherman Bernard C Modified release tablets comprising tramadol
WO2008094877A2 (en) * 2007-01-30 2008-08-07 Drugtech Corporation Compositions for oral delivery of pharmaceuticals
CA2678367C (en) * 2007-03-02 2014-07-08 Farnam Companies, Inc. Sustained release compositions using wax-like materials
AU2008286914B2 (en) * 2007-08-13 2014-10-02 Ohemo Life Sciences Inc. Abuse resistant drugs, method of use and method of making
CN101095666B (zh) * 2007-08-14 2010-10-06 石药集团欧意药业有限公司 一种盐酸曲马多缓释片剂及其制备方法
CZ300468B6 (cs) * 2007-09-20 2009-05-27 Zentiva, A. S Léková forma obsahující tramadol s kontrolovaným uvolnováním po dobu 24 hodin a zpusob její prípravy
US20100285119A1 (en) * 2008-01-11 2010-11-11 Jubilant Organosys Ltd. Multiparticulate Extended Release Pharmaceutical Composition Of Carbamazepine And Process For Manufacturing The Same
US20100003322A1 (en) * 2008-07-03 2010-01-07 Lai Felix S Enteric coated hydrophobic matrix formulation
WO2010028290A1 (en) * 2008-09-04 2010-03-11 Farnam Companies, Inc. Chewable sustained release formulations
FR2938431B1 (fr) * 2008-11-14 2013-12-20 Debregeas Et Associes Pharma Nouvelle composition a base d'acide gamma-hydroxybutyrique
AU2009317280B2 (en) 2008-11-18 2014-03-06 Ucb Pharma, S.A. Prolonged release formulations comprising an 2 -oxo- 1 -pyrrolidine derivative
US20100233259A1 (en) * 2008-12-12 2010-09-16 Pascal Grenier Dosage form of ropinirole
FR2949062B1 (fr) 2009-08-12 2011-09-02 Debregeas Et Associes Pharma Nouvelles formulations pharmaceutiques contre le mesusage des medicaments
FR2949061B1 (fr) 2009-08-12 2013-04-19 Debregeas Et Associes Pharma Microgranules flottants
AR082189A1 (es) 2010-07-06 2012-11-21 Gruenenthal Gmbh Formas de dosificacion gastrorretentivas, procedimiento
BR112015000320B1 (pt) 2012-07-12 2023-03-07 SpecGx LLC Composições farmacêuticas dissuasivas de abuso e seu processo de preparação
WO2014146093A2 (en) 2013-03-15 2014-09-18 Inspirion Delivery Technologies, Llc Abuse deterrent compositions and methods of use
US10729685B2 (en) 2014-09-15 2020-08-04 Ohemo Life Sciences Inc. Orally administrable compositions and methods of deterring abuse by intranasal administration
IT201800011125A1 (it) * 2018-12-14 2020-06-14 Dpl Pharma S P A Composizioni farmaceutiche orali solide comprendenti matrici monolitiche complesse per la somministrazione cronotropica di medicamenti nel tratto gastroenterico

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US4415547A (en) * 1982-06-14 1983-11-15 Sterling Drug Inc. Sustained-release pharmaceutical tablet and process for preparation thereof
JPS62103012A (ja) * 1985-10-23 1987-05-13 Eisai Co Ltd 多重顆粒
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US5344657A (en) * 1988-04-27 1994-09-06 Elf Sanofi Microbeads of diltiazem, a process for their manufacture and a substained-release pharmaceutical composition containing them
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DE19630035A1 (de) * 1996-07-25 1998-01-29 Asta Medica Ag Tramadol Multiple Unit Formulierungen

Also Published As

Publication number Publication date
AR008002A1 (es) 1999-11-24
DE59706441D1 (de) 2002-03-28
HUP9903053A2 (hu) 2000-01-28
CA2211284A1 (en) 1998-01-25
PT917463E (pt) 2002-07-31
PL188834B1 (pl) 2005-04-29
NO990261D0 (no) 1999-01-21
HUP9903053A3 (en) 2000-02-28
AU737121B2 (en) 2001-08-09
RU2201223C2 (ru) 2003-03-27
KR20000029530A (ko) 2000-05-25
CN1226824A (zh) 1999-08-25
UA52679C2 (uk) 2003-01-15
AU3849197A (en) 1998-02-20
ES2171268T3 (es) 2002-09-01
BG103158A (en) 1999-08-31
TW495363B (en) 2002-07-21
BR9710761A (pt) 1999-08-17
IL127915A0 (en) 1999-11-30
IL127915A (en) 2001-08-08
EE03742B1 (et) 2002-06-17
US6436438B1 (en) 2002-08-20
HU227971B1 (en) 2012-07-30
SK9899A3 (en) 1999-09-10
CA2211284C (en) 2001-10-23
ATE213408T1 (de) 2002-03-15
US5955104A (en) 1999-09-21
ZA975408B (en) 1998-01-05
JP3631762B2 (ja) 2005-03-23
KR100474793B1 (ko) 2005-03-08
CN1111402C (zh) 2003-06-18
NO990261L (no) 1999-01-21
CZ18599A3 (cs) 1999-04-14
NZ333822A (en) 1999-11-29
JP2000515871A (ja) 2000-11-28
NO324207B1 (no) 2007-09-10
WO1998004249A3 (de) 1998-04-30
WO1998004249A2 (de) 1998-02-05
EP0917463B1 (de) 2002-02-20
CZ296964B6 (cs) 2006-08-16
DK0917463T3 (da) 2002-06-10
BG63708B1 (bg) 2002-10-31
SK285300B6 (sk) 2006-10-05
HK1020876A1 (en) 2000-05-26
PL331387A1 (en) 1999-07-05
DE19630035A1 (de) 1998-01-29
EP0917463A2 (de) 1999-05-26

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