EE9900533A - Budesoniidi peenestatud kristallilisi osakesi sisaldav ravimvorm - Google Patents

Budesoniidi peenestatud kristallilisi osakesi sisaldav ravimvorm

Info

Publication number
EE9900533A
EE9900533A EEP199900533A EEP9900533A EE9900533A EE 9900533 A EE9900533 A EE 9900533A EE P199900533 A EEP199900533 A EE P199900533A EE P9900533 A EEP9900533 A EE P9900533A EE 9900533 A EE9900533 A EE 9900533A
Authority
EE
Estonia
Prior art keywords
budesonide
finely divided
pharmaceutical formulation
formulation containing
crystalline particles
Prior art date
Application number
EEP199900533A
Other languages
English (en)
Inventor
Bisrat Mikael
Moshashaee Saeed
Original Assignee
Astra Aktiebolag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Aktiebolag filed Critical Astra Aktiebolag
Publication of EE9900533A publication Critical patent/EE9900533A/et
Publication of EE03850B1 publication Critical patent/EE03850B1/et

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EEP199900533A 1997-05-23 1998-05-15 Budesoniidi peenestatud kristallilisi osakesi sisaldav ravimvorm EE03850B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9701956A SE9701956D0 (sv) 1997-05-23 1997-05-23 New composition of matter
PCT/SE1998/000908 WO1998052544A1 (en) 1997-05-23 1998-05-15 Composition comprising finely divided, crystalline particles of budesonide

Publications (2)

Publication Number Publication Date
EE9900533A true EE9900533A (et) 2000-06-15
EE03850B1 EE03850B1 (et) 2002-10-15

Family

ID=20407079

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP199900533A EE03850B1 (et) 1997-05-23 1998-05-15 Budesoniidi peenestatud kristallilisi osakesi sisaldav ravimvorm

Country Status (28)

Country Link
US (2) US6346523B1 (et)
EP (1) EP1005328B1 (et)
JP (1) JP2001525850A (et)
KR (1) KR100514971B1 (et)
CN (1) CN1146406C (et)
AR (1) AR015820A1 (et)
AT (1) ATE246492T1 (et)
AU (1) AU734763B2 (et)
BR (1) BR9808812A (et)
CA (1) CA2290538C (et)
DE (1) DE69816997T2 (et)
DK (1) DK1005328T3 (et)
EE (1) EE03850B1 (et)
ES (1) ES2205496T3 (et)
HU (1) HUP0002212A3 (et)
ID (1) ID24332A (et)
IL (1) IL133098A (et)
IS (1) IS5254A (et)
NO (1) NO995540L (et)
NZ (1) NZ500852A (et)
PL (1) PL336902A1 (et)
PT (1) PT1005328E (et)
SE (1) SE9701956D0 (et)
SK (1) SK158799A3 (et)
TR (1) TR199902880T2 (et)
TW (1) TW518236B (et)
WO (1) WO1998052544A1 (et)
ZA (1) ZA984127B (et)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996025918A1 (en) * 1995-02-24 1996-08-29 Nanosystems L.L.C. Aerosols containing nanoparticle dispersions
RU2271851C2 (ru) 2000-03-03 2006-03-20 Бёрингер Ингельхайм Фармасьютиклз, Инк. Обработка материалов многократным расширением-сжатием растворителя
EP1354581A4 (en) * 2000-12-26 2007-07-04 Takeda Pharmaceutical POROUS SUBSTANCE AND METHOD FOR THE PRODUCTION THEREOF
GB0106403D0 (en) * 2001-03-15 2001-05-02 Pharmaceutical Profiles Labelling of dry powder formulations for inhalation
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
JP2004537401A (ja) 2001-08-08 2004-12-16 ブラウン ユニバーシティ リサーチ ファウンデーション 疎水性薬物の微粉砕方法
DE60211004T2 (de) * 2001-10-10 2006-08-31 Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield Pulververarbeitung mit unter druck stehenden gasförmigen fluids
US20030129242A1 (en) * 2002-01-04 2003-07-10 Bosch H. William Sterile filtered nanoparticulate formulations of budesonide and beclomethasone having tyloxapol as a surface stabilizer
US7582284B2 (en) 2002-04-17 2009-09-01 Nektar Therapeutics Particulate materials
GB0216562D0 (en) * 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
JP2007501683A (ja) 2003-05-22 2007-02-01 エラン ファーマ インターナショナル リミテッド γ線照射によるナノ粒子活性物質分散体の滅菌法
TWI359675B (en) 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
US20070020298A1 (en) * 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether gamma-cyclodextrin and corticosteroid
US20070020196A1 (en) * 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid prepared from a unit dose suspension
US20070020299A1 (en) * 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
ATE446581T1 (de) * 2004-03-12 2009-11-15 Trinity College Dublin Magnetoresistives medium
CN101312713A (zh) * 2005-03-18 2008-11-26 纳米材料科技有限公司 可吸入的药物
EP1904219A4 (en) 2005-07-15 2011-07-27 Map Pharmaceuticals Inc METHOD FOR FORMING PARTICLES
EP1782839A1 (en) 2005-11-03 2007-05-09 Genetic S.p.A. Sterilization process of Glucocorticosteroid by supercritical CO2
US20070249572A1 (en) * 2005-12-20 2007-10-25 Verus Pharmaceuticals, Inc. Systems and methods for the delivery of corticosteroids
US20070178049A1 (en) * 2005-12-20 2007-08-02 Verus Pharmaceuticals, Inc. Systems and methods for the delivery of corticosteroids having an enhanced pharmacokinetic profile
US20070197486A1 (en) * 2005-12-20 2007-08-23 Verus Pharmaceuticals, Inc. Methods and systems for the delivery of corticosteroids
US20070185066A1 (en) * 2005-12-20 2007-08-09 Verus Pharmaceuticals, Inc. Systems and methods for the delivery of corticosteroids
US20070160542A1 (en) * 2005-12-20 2007-07-12 Verus Pharmaceuticals, Inc. Methods and systems for the delivery of corticosteroids having an enhanced pharmacokinetic profile
US20070178051A1 (en) * 2006-01-27 2007-08-02 Elan Pharma International, Ltd. Sterilized nanoparticulate glucocorticosteroid formulations
WO2007095341A2 (en) * 2006-02-15 2007-08-23 Tika Läkemedel Ab Sterilization of corticosteroids with reduced mass loss
DK2425820T3 (en) 2007-02-11 2015-07-13 Map Pharmaceuticals Inc A method for the therapeutic administration of DHE in order to enable quick relief of migraine, while minimizing the adverse event profile
US12370352B2 (en) 2007-06-28 2025-07-29 Cydex Pharmaceuticals, Inc. Nasal and ophthalmic delivery of aqueous corticosteroid solutions
US20100298602A1 (en) * 2009-05-19 2010-11-25 Massachusetts Institute Of Technology Systems and methods for microfluidic crystallization
US20100294986A1 (en) * 2009-05-19 2010-11-25 Massachusetts Institute Of Technology Supercritical fluid facilitated particle formation in microfluidic systems
EP2618816A4 (en) * 2010-09-22 2014-10-29 Map Pharmaceuticals Ltd AEROSOL COMPOSITION FOR THE ADMINISTRATION OF MEDICAMENTS
CN102975731B (zh) * 2012-04-24 2015-08-12 南车南京浦镇车辆有限公司 轨道车辆司机室骨架与车体的安装结构
WO2021219230A1 (en) 2020-04-30 2021-11-04 Paolo Fiorina Antiviral treatment
KR102567655B1 (ko) 2020-11-13 2023-08-17 주식회사 비츠로이엠 진공커패시터 및 진공커패시터 제조 방법
KR102739398B1 (ko) 2021-11-17 2024-12-06 주식회사 비츠로이엠 가변형 진공 커패시터
KR102739399B1 (ko) 2021-11-17 2024-12-06 주식회사 비츠로이엠 가변형 진공 커패시터의 나선형 전극 위치 결정구조

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1282405C (en) 1984-05-21 1991-04-02 Michael R. Violante Method for making uniformly sized particles from water-insoluble organic compounds
AU624421B2 (en) 1988-10-05 1992-06-11 Pharmacia & Upjohn Company Finely divided solid crystalline powders via precipitation into an anti-solvent
GB9001635D0 (en) 1990-01-24 1990-03-21 Ganderton David Aerosol carriers
DE69112917T2 (de) 1990-06-15 1996-05-15 Merck & Co Inc Kristallisationsverfahren zur Verbesserung der Kristallstruktur und -grösse.
SE9302777D0 (sv) 1993-08-27 1993-08-27 Astra Ab Process for conditioning substances
US5874063A (en) * 1991-04-11 1999-02-23 Astra Aktiebolag Pharmaceutical formulation
SG48301A1 (en) * 1991-12-18 1998-04-17 Astra Ab New combination
GB9313642D0 (en) * 1993-07-01 1993-08-18 Glaxo Group Ltd Method and apparatus for the formation of particles
SE9501384D0 (sv) 1995-04-13 1995-04-13 Astra Ab Process for the preparation of respirable particles

Also Published As

Publication number Publication date
TR199902880T2 (xx) 2000-02-21
AR015820A1 (es) 2001-05-30
EP1005328A1 (en) 2000-06-07
BR9808812A (pt) 2000-07-18
DE69816997D1 (de) 2003-09-11
ID24332A (id) 2000-07-13
SK158799A3 (en) 2000-05-16
NZ500852A (en) 2001-07-27
IL133098A (en) 2005-03-20
ZA984127B (en) 1998-11-23
PT1005328E (pt) 2003-11-28
CA2290538C (en) 2007-01-02
US20020037257A1 (en) 2002-03-28
IS5254A (is) 1999-11-18
DE69816997T2 (de) 2004-07-22
TW518236B (en) 2003-01-21
ATE246492T1 (de) 2003-08-15
AU7680098A (en) 1998-12-11
EP1005328B1 (en) 2003-08-06
ES2205496T3 (es) 2004-05-01
SE9701956D0 (sv) 1997-05-23
DK1005328T3 (da) 2003-11-17
KR100514971B1 (ko) 2005-09-15
NO995540D0 (no) 1999-11-12
PL336902A1 (en) 2000-07-17
NO995540L (no) 1999-11-12
IL133098A0 (en) 2001-03-19
EE03850B1 (et) 2002-10-15
CA2290538A1 (en) 1998-11-26
JP2001525850A (ja) 2001-12-11
HUP0002212A3 (en) 2001-04-28
CN1257424A (zh) 2000-06-21
US6468994B2 (en) 2002-10-22
HUP0002212A2 (hu) 2000-12-28
US6346523B1 (en) 2002-02-12
AU734763B2 (en) 2001-06-21
CN1146406C (zh) 2004-04-21
KR20010012821A (ko) 2001-02-26
WO1998052544A1 (en) 1998-11-26

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Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20021231

KB4A Valid patent at the end of a year

Effective date: 20031231

MM4A Lapsed by not paying the annual fees

Effective date: 20040515