EE9900593A - Omeprasooli naatriumisool - Google Patents

Omeprasooli naatriumisool

Info

Publication number: EE9900593A
Authority: EE; Estonia
Prior art keywords: sodium salt; omeprazole sodium; omeprazole; salt; sodium
Prior art date: 1997-06-27

Application number

EEP199900593A

Other languages

English (en)

Inventor

Gustavsson Anders

Kjellbom Kristina

Ymn Ingvar

Original Assignee

Astra Aktiebolag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-06-27

Filing date

1998-06-11

Publication date

2000-08-15

1998-06-11 Application filed by Astra Aktiebolag filed Critical Astra Aktiebolag

2000-08-15 Publication of EE9900593A publication Critical patent/EE9900593A/et

2002-02-15 Publication of EE03613B1 publication Critical patent/EE03613B1/et

Links

RRFCKCAQHRITRG-UHFFFAOYSA-N sodium;5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-3-ide;hydrate Chemical compound O.[Na+].N=1C2=CC(OC)=CC=C2[N-]C=1S(=O)CC1=NC=C(C)C(OC)=C1C RRFCKCAQHRITRG-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

EEP199900593A 1997-06-27 1998-06-11 Omeprasooli naatriumisool,selle valmistamise protsess,seda sisaldav ravimkoostis ja selle kasutamine seedetrakti häirete ravimiseks EE03613B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE9702483A SE510643C2 (sv)	1997-06-27	1997-06-27	Termodynamiskt stabil omeprazol natrium form B
PCT/SE1998/001124 WO1999000380A1 (en)	1997-06-27	1998-06-11	Omeprazole sodium salt

Publications (2)

Publication Number	Publication Date
EE9900593A true EE9900593A (et)	2000-08-15
EE03613B1 EE03613B1 (et)	2002-02-15

Family

ID=20407555

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP199900593A EE03613B1 (et)	1997-06-27	1998-06-11	Omeprasooli naatriumisool,selle valmistamise protsess,seda sisaldav ravimkoostis ja selle kasutamine seedetrakti häirete ravimiseks

Country Status (34)

Country	Link
US (1)	US6207188B1 (et)
EP (2)	EP1186602A3 (et)
JP (1)	JP3377218B2 (et)
KR (1)	KR100580987B1 (et)
CN (1)	CN1134432C (et)
AR (1)	AR013350A1 (et)
AT (1)	ATE233756T1 (et)
AU (1)	AU750239B2 (et)
BR (1)	BR9810483A (et)
CA (1)	CA2294614C (et)
CZ (1)	CZ296723B6 (et)
DE (1)	DE69811892T2 (et)
DK (1)	DK0991641T3 (et)
EE (1)	EE03613B1 (et)
EG (1)	EG24224A (et)
ES (1)	ES2191944T3 (et)
HU (1)	HU227976B1 (et)
ID (1)	ID24829A (et)
IL (2)	IL133559A0 (et)
IS (1)	IS1946B (et)
MY (1)	MY127871A (et)
NO (1)	NO318245B1 (et)
NZ (1)	NZ501929A (et)
PL (1)	PL190869B1 (et)
PT (1)	PT991641E (et)
RU (1)	RU2186778C2 (et)
SA (1)	SA98190410B1 (et)
SE (1)	SE510643C2 (et)
SK (1)	SK283958B6 (et)
TR (1)	TR199903270T2 (et)
TW (1)	TW483758B (et)
UA (1)	UA58556C2 (et)
WO (1)	WO1999000380A1 (et)
ZA (1)	ZA985317B (et)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6489346B1 (en)	1996-01-04	2002-12-03	The Curators Of The University Of Missouri	Substituted benzimidazole dosage forms and method of using same
GB2324093A (en)	1996-01-04	1998-10-14	Rican Limited	Helicobacter pylori bacterioferritin
US5840737A (en)	1996-01-04	1998-11-24	The Curators Of The University Of Missouri	Omeprazole solution and method for using same
SE510643C2 (sv)	1997-06-27	1999-06-14	Astra Ab	Termodynamiskt stabil omeprazol natrium form B
SE9900274D0 (sv) *	1999-01-28	1999-01-28	Astra Ab	New compound
WO2000071122A1 (en) *	1999-05-20	2000-11-30	Par Pharmaceutical, Inc.	Stabilized composition based on pyridinyl-sulfinyl-benzimidazoles and process
SE9903831D0 (sv)	1999-10-22	1999-10-22	Astra Ab	Formulation of substituted benzimidazoles
SE0000774D0 (sv) *	2000-03-08	2000-03-08	Astrazeneca Ab	New formulation
SE0000773D0 (sv) *	2000-03-08	2000-03-08	Astrazeneca Ab	New formulation
EP1706397A4 (en) *	2000-05-15	2007-08-01	Ranbaxy Lab Ltd	AMORPHOUS FORM OF OMEPRAZOLE SALTS
CA2417311C (en) *	2000-08-04	2012-07-10	Takeda Chemical Industries, Ltd.	Crystalline alkali metal salts of lansoprazole and their production and use
CA2419067C (en)	2000-08-18	2008-12-23	Takeda Chemical Industries, Ltd.	Injectable composition comprising benzimidazole compound and strong alkali
US8206741B2 (en)	2001-06-01	2012-06-26	Pozen Inc.	Pharmaceutical compositions for the coordinated delivery of NSAIDs
EP1411900B2 (en) *	2001-06-01	2013-12-04	Pozen, Inc.	PHARMACEUTICAL COMPOSITIONS FOR THE COORDINATED DELIVERY OF NSAIDs
KR100433735B1 (ko) *	2001-06-27	2004-06-04	주식회사 씨트리	결정형 ⅰ을 갖는 란소프라졸의 제조방법
SE0102993D0 (sv)	2001-09-07	2001-09-07	Astrazeneca Ab	New self emulsifying drug delivery system
AU2003278406A1 (en) *	2002-10-22	2004-05-13	Ranbaxy Laboratories Limited	Amorphous form of esomeprazole salts
US20070060556A1 (en)	2003-05-05	2007-03-15	Yatendra Kumar	Barium salt of benzimidazole derivative
US8993599B2 (en)	2003-07-18	2015-03-31	Santarus, Inc.	Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en)	2004-05-25	2014-12-09	Santarus, Inc.	Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
FR2871800B1 (fr) *	2004-06-17	2006-08-25	Sidem Pharma Sa Sa	Sel de sodium monohydrate du s-tenatoprazole et application en therapeutique
CA2570795C (en) *	2004-06-24	2013-05-28	Astrazeneca Ab	Process for the preparation of crystal modifications for use in the preparation of esomeprazole sodium salt
WO2006073779A1 (en) *	2004-12-30	2006-07-13	Transform Phamaceuticals, Inc.	Novel omeprazole forms and related methods
WO2006131338A2 (en) *	2005-06-08	2006-12-14	Lek Pharmaceuticals D.D.	Crystalline solvate of omeprazole sodium
EA201100313A1 (ru)	2008-09-09	2011-10-31	Астразенека Аб	Способ доставки фармацевтической композиции пациенту, нуждающемуся в этом
CN101412710B (zh) *	2008-12-16	2010-04-21	海南百那医药发展有限公司	一种奥美拉唑钠化合物及其制法
CA2764963C (en)	2009-06-25	2016-11-01	Astrazeneca Ab	Method for treating a patient at risk for developing an nsaid-associated ulcer
US20110008432A1 (en) *	2009-06-25	2011-01-13	Pozen Inc.	Method for Treating a Patient in Need of Aspirin Therapy
CN102351846B (zh) *	2011-09-07	2012-08-22	周晓东	一种新的奥美拉唑钠化合物及其药物组合物
CN102319223B (zh) *	2011-09-21	2013-06-19	石药集团欧意药业有限公司	一种埃索美拉唑冻干制剂及其制备方法
CN102512380B (zh) *	2011-12-20	2013-04-17	海南锦瑞制药股份有限公司	一种以奥美拉唑钠为活性成分的冻干粉针剂及其制备方法
BR112014016085A8 (pt)	2011-12-28	2017-07-04	Pozen Inc	composições aprimoradas e métodos para distribuição de omeprazol mais ácido acetilsalicílico
CN102827147B (zh) *	2012-09-13	2013-08-07	山东罗欣药业股份有限公司	一种奥美拉唑钠晶体化合物及含有该晶体化合物的药物组合物
CN102871973A (zh) *	2012-10-16	2013-01-16	浙江亚太药业股份有限公司	一种奥美拉唑钠冻干制剂及其制备方法
CN103012371B (zh) *	2013-01-05	2014-02-12	宁辉	奥美拉唑钠结晶化合物、其制备方法及其药物组合物
CN103570687B (zh) *	2013-11-15	2015-01-07	悦康药业集团有限公司	一种奥美拉唑钠晶体化合物
CN104788426B (zh) *	2015-04-02	2015-12-30	天津大学	一种奥美拉唑钠半水合物及其制备方法
WO2024075017A1 (en)	2022-10-04	2024-04-11	Zabirnyk Arsenii	Inhibition of aortic valve calcification
CN116041325B (zh) *	2022-12-09	2025-03-07	山东北大高科华泰制药有限公司	稳定化质子泵抑制剂的方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2719916C2 (de) *	1977-05-04	1987-03-19	Kali-Chemie Pharma Gmbh, 3000 Hannover	Verfahren zur Herstellung von 2,9-Dioxatricyclo[4,3,1,0↑3↑↑,↑↑7↑]decanen
SE7804231L (sv)	1978-04-14	1979-10-15	Haessle Ab	Magsyrasekretionsmedel
SE8301182D0 (sv) *	1983-03-04	1983-03-04	Haessle Ab	Novel compounds
GB2189698A (en)	1986-04-30	1987-11-04	Haessle Ab	Coated omeprazole tablets
SE9002043D0 (sv) *	1990-06-07	1990-06-07	Astra Ab	Improved method for synthesis
ES2023778A6 (es) *	1990-12-12	1992-02-01	Genesis Para La Investigacion	Procedimiento para preparar sales alcalinas del omeprazol
SE9301830D0 (sv) *	1993-05-28	1993-05-28	Ab Astra	New compounds
WO1995032957A1 (en) *	1994-05-27	1995-12-07	Astra Aktiebolag	Novel ethoxycarbonyloxymethyl derivatives of substituted benzimidazoles
CZ289804B6 (cs)	1994-07-08	2002-04-17	Astrazeneca Ab	Multijednotková tabletovaná dávková forma I
SE504459C2 (sv) *	1994-07-15	1997-02-17	Astra Ab	Förfarande för framställning av substituerade sulfoxider
CN1042423C (zh) *	1995-05-25	1999-03-10	常州市第四制药厂	奥美拉唑盐水合物及其制备方法
WO1998040377A1 (en) *	1997-03-07	1998-09-17	A/S Gea Farmaceutisk Fabrik	Process for the preparation of 2-[[(2-pyridinyl)methyl]sulfinyl]-1h-benzimidazoles and novel compounds of use for such purpose
AU5982298A (en) *	1997-03-07	1998-09-29	A/S Gea Farmaceutisk Fabrik	Process for the preparation of 2-{{(2-pyridinyl)me thyl}sulfinyl}-1h-benzimidazoles and novel compounds of use for such purpos
SE510643C2 (sv)	1997-06-27	1999-06-14	Astra Ab	Termodynamiskt stabil omeprazol natrium form B

1997
- 1997-06-27 SE SE9702483A patent/SE510643C2/sv not_active IP Right Cessation
1998
- 1998-06-11 PL PL337735A patent/PL190869B1/pl unknown
- 1998-06-11 EP EP01128973A patent/EP1186602A3/en not_active Withdrawn
- 1998-06-11 BR BR9810483-7A patent/BR9810483A/pt not_active Application Discontinuation
- 1998-06-11 JP JP50548499A patent/JP3377218B2/ja not_active Expired - Lifetime
- 1998-06-11 DK DK98931166T patent/DK0991641T3/da active
- 1998-06-11 ES ES98931166T patent/ES2191944T3/es not_active Expired - Lifetime
- 1998-06-11 NZ NZ501929A patent/NZ501929A/en not_active IP Right Cessation
- 1998-06-11 EE EEP199900593A patent/EE03613B1/et not_active IP Right Cessation
- 1998-06-11 PT PT98931166T patent/PT991641E/pt unknown
- 1998-06-11 RU RU2000100361/04A patent/RU2186778C2/ru active
- 1998-06-11 AT AT98931166T patent/ATE233756T1/de active
- 1998-06-11 AU AU81353/98A patent/AU750239B2/en not_active Expired
- 1998-06-11 KR KR1019997012236A patent/KR100580987B1/ko not_active Expired - Fee Related
- 1998-06-11 EP EP98931166A patent/EP0991641B1/en not_active Expired - Lifetime
- 1998-06-11 WO PCT/SE1998/001124 patent/WO1999000380A1/en not_active Ceased
- 1998-06-11 ID IDW991685A patent/ID24829A/id unknown
- 1998-06-11 US US09/101,081 patent/US6207188B1/en not_active Expired - Lifetime
- 1998-06-11 DE DE69811892T patent/DE69811892T2/de not_active Expired - Lifetime
- 1998-06-11 CA CA002294614A patent/CA2294614C/en not_active Expired - Lifetime
- 1998-06-11 CZ CZ0469999A patent/CZ296723B6/cs not_active IP Right Cessation
- 1998-06-11 CN CNB988066165A patent/CN1134432C/zh not_active Expired - Lifetime
- 1998-06-11 TR TR1999/03270T patent/TR199903270T2/xx unknown
- 1998-06-11 SK SK1729-99A patent/SK283958B6/sk not_active IP Right Cessation
- 1998-06-11 IL IL13355998A patent/IL133559A0/xx active IP Right Grant
- 1998-06-11 HU HU0003017A patent/HU227976B1/hu not_active IP Right Cessation
- 1998-06-15 TW TW087109498A patent/TW483758B/zh not_active IP Right Cessation
- 1998-06-16 AR ARP980102857A patent/AR013350A1/es active IP Right Grant
- 1998-06-18 ZA ZA985317A patent/ZA985317B/xx unknown
- 1998-06-24 EG EG74298A patent/EG24224A/xx active
- 1998-06-26 MY MYPI98002907A patent/MY127871A/en unknown
- 1998-08-19 SA SA98190410A patent/SA98190410B1/ar unknown
- 1998-11-06 UA UA99126959A patent/UA58556C2/uk unknown
1999
- 1999-12-16 IL IL133559A patent/IL133559A/en not_active IP Right Cessation
- 1999-12-21 IS IS5314A patent/IS1946B/is unknown
- 1999-12-23 NO NO19996440A patent/NO318245B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
NO318245B1 (no)	2005-02-21
IS1946B (is)	2004-10-13
WO1999000380A1 (en)	1999-01-07
US6207188B1 (en)	2001-03-27
DE69811892D1 (de)	2003-04-10
CA2294614C (en)	2002-01-08
KR100580987B1 (ko)	2006-05-17
HUP0003017A2 (hu)	2001-06-28
AU750239B2 (en)	2002-07-11
RU2186778C2 (ru)	2002-08-10
CN1261362A (zh)	2000-07-26
EP0991641A1 (en)	2000-04-12
DE69811892T2 (de)	2004-03-04
ID24829A (id)	2000-08-24
CA2294614A1 (en)	1999-01-07
PT991641E (pt)	2003-06-30
NZ501929A (en)	2001-06-29
SE9702483D0 (sv)	1997-06-27
EP1186602A3 (en)	2002-03-27
NO996440L (no)	2000-02-08
IL133559A (en)	2006-04-10
HK1026699A1 (en)	2000-12-22
MY127871A (en)	2006-12-29
NO996440D0 (no)	1999-12-23
BR9810483A (pt)	2000-09-12
DK0991641T3 (da)	2003-05-19
EE03613B1 (et)	2002-02-15
SE510643C2 (sv)	1999-06-14
IS5314A (is)	1999-12-21
JP2001508805A (ja)	2001-07-03
PL190869B1 (pl)	2006-02-28
ZA985317B (en)	1999-01-11
CZ296723B6 (cs)	2006-05-17
TW483758B (en)	2002-04-21
JP3377218B2 (ja)	2003-02-17
TR199903270T2 (xx)	2000-07-21
HU227976B1 (en)	2012-07-30
UA58556C2 (uk)	2003-08-15
AR013350A1 (es)	2000-12-27
CZ469999A3 (cs)	2000-08-16
SA98190410B1 (ar)	2006-06-10
SE9702483L (sv)	1998-12-28
KR20010014165A (ko)	2001-02-26
SK283958B6 (sk)	2004-06-08
AU8135398A (en)	1999-01-19
EP0991641B1 (en)	2003-03-05
ES2191944T3 (es)	2003-09-16
EP1186602A2 (en)	2002-03-13
EG24224A (en)	2008-11-10
SK172999A3 (en)	2000-07-11
PL337735A1 (en)	2000-08-28
CN1134432C (zh)	2004-01-14
ATE233756T1 (de)	2003-03-15
HUP0003017A3 (en)	2002-01-28
IL133559A0 (en)	2001-04-30

Legal Events

Date	Code	Title	Description
2003-02-17	KB4A	Valid patent at the end of a year	Effective date: 20021231
2004-02-16	KB4A	Valid patent at the end of a year	Effective date: 20031231
2005-02-15	KB4A	Valid patent at the end of a year	Effective date: 20041231
2006-02-15	KB4A	Valid patent at the end of a year	Effective date: 20051231
2007-02-15	KB4A	Valid patent at the end of a year	Effective date: 20061231
2008-02-15	KB4A	Valid patent at the end of a year	Effective date: 20071231
2009-02-16	KB4A	Valid patent at the end of a year	Effective date: 20081231
2010-02-15	KB4A	Valid patent at the end of a year	Effective date: 20091231
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231
2017-02-15	MM4A	Lapsed by not paying the annual fees	Effective date: 20160611

Publication	Publication Date	Title
NO996440L (no)	2000-02-08	Omeprazol-natriumsalt
DK1005446T3 (da)	2004-06-07	N-aroylphenylalaninderivater
ATE235220T1 (de)	2003-04-15	Resorcinderivate
ID22781A (id)	1999-12-09	Turunan-turunan nikotinamida
ATE284385T1 (de)	2004-12-15	Sulfonamidderivate
DE69817186D1 (de)	2003-09-18	Diaminorhodamin-derivate
DE59712204D1 (de)	2005-03-24	Radaufhängung
DE69802569D1 (de)	2002-01-03	Aufhängungseinrichtung
DK0958282T3 (da)	2004-11-29	2-Amino-6-(2-substitueret-4-phenoxy)-substitueret-pyridiner
FI20000850L (fi)	2000-04-10	Kamana
ATE255098T1 (de)	2003-12-15	Substituierte chromanderivate
DE69805807D1 (de)	2002-07-11	Mikrobiozide n-sulfonylglycin-alkynyloxyphenethylamid-derivate
ATE440854T1 (de)	2009-09-15	5-deoxy-cytidin-derivate
ATE255099T1 (de)	2003-12-15	Substituierte chromanderivate
DK0966437T3 (da)	2002-10-07	5-Aroylnaphthalenderivater
ID18027A (id)	1998-02-19	Garam amina
NO995853D0 (no)	1999-11-29	Nytt salt
DE69829682D1 (de)	2005-05-12	Cis-disubstituierte aminocycloalkyl-pyrrolidin-derivate
ATE241275T1 (de)	2003-06-15	Phosphoniumsalz-zusammensetzung
DE69828780D1 (de)	2005-03-03	Amidinocamptpthecin-derivate
NO981495L (no)	1998-10-05	Fenoksymetylpiperidin-derivater
DE69813264D1 (de)	2003-05-15	Kleiderbügel
DE69824255D1 (de)	2004-07-08	Deformylase
DK1015447T3 (da)	2002-06-17	Piperidinylmethyloxazolidinonderivat
DE69814731D1 (de)	2003-06-26	Kleiderbügel