EG10986A - A process for preparation of arylpiperazines - Google Patents

A process for preparation of arylpiperazines

Info

Publication number
EG10986A
EG10986A EG9/73A EG973A EG10986A EG 10986 A EG10986 A EG 10986A EG 9/73 A EG9/73 A EG 9/73A EG 973 A EG973 A EG 973A EG 10986 A EG10986 A EG 10986A
Authority
EG
Egypt
Prior art keywords
arylpiperazines
preparation
Prior art date
Application number
EG9/73A
Other languages
English (en)
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Application granted granted Critical
Publication of EG10986A publication Critical patent/EG10986A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/16—Preparation of halogenated hydrocarbons by replacement by halogens of hydroxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
EG9/73A 1972-01-15 1973-01-10 A process for preparation of arylpiperazines EG10986A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19722201889 DE2201889A1 (de) 1972-01-15 1972-01-15 Arylpiperazine und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
EG10986A true EG10986A (en) 1976-11-30

Family

ID=5833112

Family Applications (1)

Application Number Title Priority Date Filing Date
EG9/73A EG10986A (en) 1972-01-15 1973-01-10 A process for preparation of arylpiperazines

Country Status (21)

Country Link
US (1) US3926999A (de)
JP (1) JPS504085A (de)
AT (1) AT329062B (de)
AU (1) AU465081B2 (de)
BE (1) BE793955A (de)
BR (1) BR7300224D0 (de)
CH (1) CH587270A5 (de)
DD (1) DD104080A5 (de)
DE (1) DE2201889A1 (de)
DK (1) DK134177C (de)
EG (1) EG10986A (de)
ES (1) ES410618A1 (de)
FR (1) FR2168357B1 (de)
GB (1) GB1360959A (de)
HU (1) HU165959B (de)
IL (1) IL40854A (de)
NL (1) NL7215334A (de)
PL (1) PL83741B1 (de)
RO (1) RO62763A (de)
SE (1) SE397530B (de)
ZA (1) ZA728625B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5496334A (en) * 1978-01-17 1979-07-30 Oki Electric Ind Co Ltd Digital signal bus
US4182862A (en) * 1978-10-18 1980-01-08 Rohm And Haas Company Process for the preparation of 1,3-disubstituted-2-azoyl-2-propen-1-ones
CA1248531A (en) * 1984-04-17 1989-01-10 Jeffrey C. Watkins 4-substituted piperazine-2-carboxylic acids
US4562189A (en) * 1984-10-09 1985-12-31 American Cyanamid Company Pyrazolylpiperazines
US20040082717A1 (en) * 2002-06-24 2004-04-29 Southwest Research Institute Keratin-silicone copolymers and interpenetrating networks (IPN's), methods of production and methods of use thereof
US20050130989A1 (en) * 2003-01-28 2005-06-16 Aventis Pharma S. A. N-arylheteroaromatic products compositions containing them and use thereof
DE10315569A1 (de) 2003-04-05 2004-10-14 Merck Patent Gmbh Substituierte Pyrazolverbindungen
DE10315572A1 (de) * 2003-04-05 2004-10-14 Merck Patent Gmbh Substituierte Pyrazole
DE10315571A1 (de) 2003-04-05 2004-10-14 Merck Patent Gmbh Pyrazolverbindungen
DE10315573A1 (de) 2003-04-05 2004-10-14 Merck Patent Gmbh Substituierte Pyrazole
KR100868353B1 (ko) 2007-03-08 2008-11-12 한국화학연구원 도파민 d4 수용체 길항제인 신규 피페라지닐프로필피라졸유도체, 이의 제조방법 및 이를 포함하는 약학적 조성물
SG10201502484SA (en) * 2010-03-30 2015-05-28 Verseon Corp Multisubstituted aromatic compounds as inhibitors of thrombin
DK2968297T3 (en) 2013-03-15 2019-01-07 Verseon Inc MULTI-SUBSTITUTED AROMATIC COMPOUNDS AS SERINE PROTEASE INHIBITORS
WO2014149139A2 (en) 2013-03-15 2014-09-25 Verseon, Inc. Halogenopyrazoles as inhibitors of thrombin
JP2017528486A (ja) 2014-09-17 2017-09-28 ヴァーセオン コーポレイション セリンプロテアーゼ阻害剤としてのピラゾリル置換ピリドン化合物
ES2931460T3 (es) 2015-02-27 2022-12-29 Verseon Int Corporation Compuestos de pirazol sustituido como inhibidores de serina proteasa
US12479816B2 (en) 2019-02-08 2025-11-25 University of Pittsburgh—of the Commonwealth System of Higher Education 20-HETE formation inhibitors

Also Published As

Publication number Publication date
DK134177C (da) 1977-02-28
JPS504085A (de) 1975-01-16
AT329062B (de) 1976-04-26
FR2168357A1 (de) 1973-08-31
DD104080A5 (de) 1974-02-20
DE2201889A1 (de) 1973-07-19
FR2168357B1 (de) 1975-10-31
ZA728625B (en) 1973-08-29
SE397530B (sv) 1977-11-07
CH587270A5 (de) 1977-04-29
NL7215334A (de) 1973-07-17
BE793955A (fr) 1973-07-12
IL40854A0 (en) 1973-01-30
PL83741B1 (de) 1976-01-31
ATA26273A (de) 1975-07-15
US3926999A (en) 1975-12-16
ES410618A1 (es) 1976-06-01
AU465081B2 (en) 1975-09-18
AU4985272A (en) 1974-06-13
DK134177B (da) 1976-09-27
HU165959B (de) 1974-12-28
RO62763A (fr) 1978-01-15
GB1360959A (en) 1974-07-24
BR7300224D0 (pt) 1973-10-25
IL40854A (en) 1976-03-31

Similar Documents

Publication Publication Date Title
JPS5387333A (en) Process for preparing acyldiamine
CS185216B2 (en) Process for preparing dimethylethere
ZA728625B (en) Arylpiperazines and processes for their preparation
YU78473A (en) Process for preparing 1-hydroxy-2-pyridines
HU175725B (hu) Sposob poluchenija tetrakhlor-izoftalonitrila
KR780000072B1 (en) Process for preparing new 2-alkylamino-dihydropyridines
JPS52122349A (en) Process for preparing tntermediate of 155substituteddomegaa pentanoprostagladines
ZA735348B (en) Method of preparing a mixture
YU36015B (en) Process for preparing 1-ethyl-imidazoles
IL43385A0 (en) Process for preparing perchloro-methylmercaptane
EG11125A (en) A process for preparation of 2-alkoxy-5-alkylsulphonyl-benzoic acids
YU238572A (en) Process for preparing n-(-ethyl-delta-pyrrolidyl-methyl)-2-methoxy-5-sulfamidobenzamide
KR780000029B1 (en) Process for preparing novel benzyl-pyrimidines
YU36303B (en) Process for preparing tetramisol
IL41600A (en) A process for the preparation of alpha-6-deoxytetracyclines
ZA735801B (en) An improved process for the preparation of a catalyst
IL42226A0 (en) A process for the preparation of eburnamonines
YU141973A (en) New process for preparing 2-methoxy-5-alkylsulfonyl benzamides
EG11435A (en) Process for preparation of n(1-ethyl-2-pyrrolidylmethyl)-2-methoxy-5-ethylsulphonyl-benzamide
YU36020B (en) Process for preparing m-dioxane-5-methylamine
IL42308A0 (en) New process for the preparation of 2-methoxy-5-sulfamoyl benzoyl-n-ethyl-2-pyrrolidine-methylamine
EG10939A (en) A process for preparation of steroidalpyrazole compounds
YU212873A (en) Process for preparing bicyclomycin
YU123273A (en) Process for preparing 2-amino-benzylamines
ZA73721B (en) Process for preparing polythiodiglycol