EG12280A - Process for preparing neue 6-aryl-s-triazolo-(4,3-a)pyrido-(2,3-f)-1,4-diazepine - Google Patents

Process for preparing neue 6-aryl-s-triazolo-(4,3-a)pyrido-(2,3-f)-1,4-diazepine

Info

Publication number
EG12280A
EG12280A EG76673A EG67376A EG12280A EG 12280 A EG12280 A EG 12280A EG 76673 A EG76673 A EG 76673A EG 67376 A EG67376 A EG 67376A EG 12280 A EG12280 A EG 12280A
Authority
EG
Egypt
Prior art keywords
neue
diazepine
triazolo
pyrido
aryl
Prior art date
Application number
EG76673A
Other languages
English (en)
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Application granted granted Critical
Publication of EG12280A publication Critical patent/EG12280A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
EG76673A 1975-11-04 1976-11-02 Process for preparing neue 6-aryl-s-triazolo-(4,3-a)pyrido-(2,3-f)-1,4-diazepine EG12280A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT837275A AT350056B (de) 1975-11-04 1975-11-04 Verfahren zur herstellung von neuen pyrido- (2,3-f)-(1,4)-diazepinen, deren optischen isomeren und salzen

Publications (1)

Publication Number Publication Date
EG12280A true EG12280A (en) 1978-12-31

Family

ID=3604891

Family Applications (1)

Application Number Title Priority Date Filing Date
EG76673A EG12280A (en) 1975-11-04 1976-11-02 Process for preparing neue 6-aryl-s-triazolo-(4,3-a)pyrido-(2,3-f)-1,4-diazepine

Country Status (30)

Country Link
US (1) US4110455A (pl)
JP (1) JPS5831351B2 (pl)
AR (3) AR217814A1 (pl)
AT (1) AT350056B (pl)
AU (1) AU504228B2 (pl)
BE (1) BE847952A (pl)
CA (1) CA1076111A (pl)
CH (1) CH630920A5 (pl)
CS (1) CS191181B2 (pl)
DD (1) DD128178A5 (pl)
DE (1) DE2649116A1 (pl)
DK (1) DK142324B (pl)
EG (1) EG12280A (pl)
ES (2) ES452969A1 (pl)
FI (1) FI62088C (pl)
FR (1) FR2330404A1 (pl)
GB (1) GB1562800A (pl)
HU (1) HU177422B (pl)
IL (1) IL50816A (pl)
IN (1) IN144289B (pl)
MX (1) MX4284E (pl)
NL (1) NL7612187A (pl)
NO (1) NO146470C (pl)
PL (2) PL118308B1 (pl)
PT (1) PT65787B (pl)
RO (2) RO77294A (pl)
SE (1) SE7612260L (pl)
SU (2) SU667137A3 (pl)
YU (1) YU269176A (pl)
ZA (1) ZA766620B (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1185601A (en) * 1981-02-27 1985-04-16 Walter Hunkeler Imidazodiazepines
DE3435973A1 (de) * 1984-10-01 1986-04-10 Boehringer Ingelheim KG, 6507 Ingelheim Diazepine enthaltende pharmazeutische zusammensetzungen mit paf-antagonistischer wirkung
US4798896A (en) * 1988-01-19 1989-01-17 American Home Products Corporation Antipsychotic gamma-carboline N-oxides
TW201201813A (en) * 2010-03-31 2012-01-16 Arqule Inc Substituted benzo-pyrido-triazolo-diazepine compounds
AR084070A1 (es) 2010-12-02 2013-04-17 Constellation Pharmaceuticals Inc Inhibidores del bromodominio y usos de los mismos
WO2012075456A1 (en) 2010-12-02 2012-06-07 Constellation Pharmaceuticals Bromodomain inhibitors and uses thereof
WO2012151512A2 (en) 2011-05-04 2012-11-08 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
WO2012174487A2 (en) 2011-06-17 2012-12-20 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
WO2013184878A1 (en) 2012-06-06 2013-12-12 Constellation Pharmaceuticals, Inc. Benzo [b] isoxazoloazepine bromodomain inhibitors and uses thereof
TWI602820B (zh) 2012-06-06 2017-10-21 星宿藥物公司 溴域抑制劑及其用途
CN106687463B (zh) 2014-06-20 2019-04-09 星座制药公司 一种乙酰胺类化合物的晶型

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT327917B (de) * 1973-04-12 1976-02-25 Degussa Verfahren zur herstellung von neuen 5-aryl-pyrido- (b-6,7) -1,4-diazepinen und deren salzen
US4039551A (en) * 1976-03-15 1977-08-02 The Upjohn Company 1-[(Hydroxyamino)methyl]-6-aryl-4H-s-triazolo[4,3-a][1,4]benzodiazepines

Also Published As

Publication number Publication date
AR216915A1 (es) 1980-02-15
NO146470C (no) 1982-10-06
FR2330404A1 (fr) 1977-06-03
AR217814A1 (es) 1980-04-30
YU269176A (en) 1983-02-28
DD128178A5 (de) 1977-11-02
SE7612260L (sv) 1977-05-05
ES452971A1 (es) 1978-10-16
DK142324B (da) 1980-10-13
PL113803B1 (en) 1981-01-31
HU177422B (en) 1981-10-28
CH630920A5 (de) 1982-07-15
FI62088C (fi) 1982-11-10
MX4284E (es) 1982-03-12
JPS5831351B2 (ja) 1983-07-05
CA1076111A (en) 1980-04-22
NO146470B (no) 1982-06-28
RO77294A (ro) 1982-09-09
BE847952A (fr) 1977-05-03
SU667137A3 (ru) 1979-06-05
FR2330404B1 (pl) 1979-07-20
NO763739L (pl) 1977-05-05
FI763158A7 (pl) 1977-05-05
GB1562800A (en) 1980-03-19
RO70245A (ro) 1981-06-30
PL193439A1 (pl) 1979-07-16
DE2649116A1 (de) 1977-05-18
IL50816A0 (en) 1977-01-31
AU1931176A (en) 1978-05-11
JPS5259194A (en) 1977-05-16
ZA766620B (en) 1977-12-28
PL118308B1 (en) 1981-09-30
IN144289B (pl) 1978-04-22
DK497076A (pl) 1977-05-05
ES452969A1 (es) 1977-11-16
SU676165A3 (ru) 1979-07-25
DK142324C (pl) 1981-03-02
PT65787B (de) 1978-05-10
PT65787A (de) 1976-12-01
IL50816A (en) 1980-09-16
NL7612187A (nl) 1977-05-06
US4110455A (en) 1978-08-29
CS191181B2 (en) 1979-06-29
ATA837275A (de) 1978-10-15
AT350056B (de) 1979-05-10
AU504228B2 (en) 1979-10-04
FI62088B (fi) 1982-07-30
AR216916A1 (es) 1980-02-15

Similar Documents

Publication Publication Date Title
HU178129B (en) Process for preparing 21-phenyl-sulphinyl-20-alkoxy-pregna-4,17/20/-dien-3-ones
YU19876A (en) Process for obtaining 1,2,3-thiadiazolyl-carbamide
YU146285A (en) Process for making 3',4'-dideoxicanamycine b
PT65787B (de) Neue 6-aryl-s-triazolo-(4,3-a)-pyrido-(2,3-f)-1,4-diazepine
AU1710176A (en) 3-phenylspiro(isobenzofuran-1,4'-piperidine)-sulfenamides andderivatives
YU39481B (en) Process for the manufacture of 1-alkyl-1-(beta-alkoxycarboethyl)-1,2,3,4,6,7,12,12b-octahydroindolo(2,3-a)-quinolizine
CS191982B2 (en) Process for preparing 3,7-dimethyl-3-hydroxyoctannitrile
JPS5214705A (en) Process for preparing 22chlorobutadienee1*3
JPS5246006A (en) Process for preparing 2*33dichloroo1*33butadiene
JPS5283309A (en) Process for preparing 1*11dihaloo44methyll1*33pentadiene
YU258476A (en) Process for preparing 2,9-dioxa-triyclo-4,3,1,0,3,7,-decanes
JPS51138634A (en) Process for preparing 2*55dimethoxyy44 chloroaniline
JPS51143637A (en) Process for preparing 3*55diitertt butyll44hydroxybenzaldehyde
GB1545521A (en) 10-substituted-4h-benzo(4,5)cyclohepta(1,2-b)-thiophens
JPS51131840A (en) Process for preparing nnacetoacetyll2*55 dimethoxyy44chloroanilide
JPS51136604A (en) Process for preparing 1*11dichloroo44methylpentaa1*33diene
JPS51143602A (en) Process for preparing 1*11dihaloo1*33diene
JPS5251304A (en) Process for preparing 1*11difluoroethane
YU42626B (en) Process for making 3',4'-dideoxykanamycine b
JPS5210264A (en) 1*33dihydroo33phenyll1***22 propynyl* spiro *isobenzofurane*
JPS51150846A (en) Forming machine for underdrain
JPS527907A (en) Process for preparing 1*11dihaloo44methylpentadiene
YU175376A (en) Process for preparing substituted 6-aryl-4h-s-triazolo-(3,4-c)-thieno-(2,3-e)-1,4-diazepines
CS192554B2 (en) Process for preparing 3,5-diphenylpyrazolones
CS180895B1 (en) Process for preparing methyl-1,2,2-tri-0-acetyl-4-0-methyl- - d-glukopyranuronate