EG19353A - Ligand- containing medium for chromatographic separation, process for preparing the medium, and use of the medium for isolating synthetic or natural molecules from a fluid mixture - Google Patents

Ligand- containing medium for chromatographic separation, process for preparing the medium, and use of the medium for isolating synthetic or natural molecules from a fluid mixture

Info

Publication number: EG19353A
Authority: EG; Egypt
Prior art keywords: medium; ligand; preparing; media; chromatographic separation
Prior art date: 1989-09-29

Application number

EG56990A

Other languages

English (en)

Inventor

Ferdinand Cal Haase

Original Assignee

Rohm & Haas

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-09-29

Filing date

1990-09-26

Publication date

1994-12-30

1990-09-26 Application filed by Rohm & Haas filed Critical Rohm & Haas

1994-12-30 Application granted granted Critical

1994-12-30 Publication of EG19353A publication Critical patent/EG19353A/xx

Links

238000004519 manufacturing process Methods 0.000 title abstract 2
238000013375 chromatographic separation Methods 0.000 title 1
239000012530 fluid Substances 0.000 title 1
239000000203 mixture Substances 0.000 title 1
108090001008 Avidin Proteins 0.000 abstract 2
239000003446 ligand Substances 0.000 abstract 2
108090000765 processed proteins & peptides Proteins 0.000 abstract 2
108090000623 proteins and genes Proteins 0.000 abstract 2
102000004169 proteins and genes Human genes 0.000 abstract 2
108091034117 Oligonucleotide Proteins 0.000 abstract 1
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 1
230000006287 biotinylation Effects 0.000 abstract 1
238000007413 biotinylation Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000002773 nucleotide Substances 0.000 abstract 1
125000003729 nucleotide group Chemical group 0.000 abstract 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 1
238000000926 separation method Methods 0.000 abstract 1
239000007787 solid Substances 0.000 abstract 1
239000000758 substrate Substances 0.000 abstract 1

Classifications

- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
- B01D15/3804—Affinity chromatography
- B01D15/3823—Affinity chromatography of other types, e.g. avidin, streptavidin or biotin
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
- B01J20/3206—Organic carriers, supports or substrates
- B01J20/3208—Polymeric carriers, supports or substrates
- B01J20/321—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
- B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
- B01J20/3219—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3268—Macromolecular compounds
- B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
- B01J20/3274—Proteins, nucleic acids, polysaccharides, antibodies or antigens
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
- Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
- Y10S530/815—Carrier is a synthetic polymer
- Y10S530/816—Attached to the carrier via a bridging agent

Landscapes

Chemical & Material Sciences (AREA)
Analytical Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Biochemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Treatment Of Liquids With Adsorbents In General (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Peptides Or Proteins (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Enzymes And Modification Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

EG56990A 1989-09-29 1990-09-26 Ligand- containing medium for chromatographic separation, process for preparing the medium, and use of the medium for isolating synthetic or natural molecules from a fluid mixture EG19353A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US41478589A	1989-09-29	1989-09-29

Publications (1)

Publication Number	Publication Date
EG19353A true EG19353A (en)	1994-12-30

Family

ID=23642952

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EG56990A EG19353A (en)	1989-09-29	1990-09-26	Ligand- containing medium for chromatographic separation, process for preparing the medium, and use of the medium for isolating synthetic or natural molecules from a fluid mixture

Country Status (18)

Country	Link
US (1)	US5276062A (de)
EP (1)	EP0423938B1 (de)
JP (1)	JPH03197500A (de)
KR (1)	KR910006320A (de)
AT (1)	ATE102074T1 (de)
BR (1)	BR9004848A (de)
CA (1)	CA2025487A1 (de)
DE (1)	DE69007006T2 (de)
DK (1)	DK0423938T3 (de)
EG (1)	EG19353A (de)
ES (1)	ES2062394T3 (de)
IL (1)	IL95772A (de)
NO (1)	NO180558C (de)
NZ (1)	NZ235480A (de)
PL (1)	PL287102A1 (de)
PT (1)	PT95468B (de)
TR (1)	TR26082A (de)
ZA (1)	ZA907678B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5556748A (en) *	1991-07-30	1996-09-17	Xenopore Corporation	Methods of sandwich hybridization for the quantitative analysis of oligonucleotides
BE1006312A3 (fr) *	1991-11-29	1994-07-19	Univ Catholique Louvain	Procede de selection de microorganismes recombinants comportant a leur surface au moins une molecule a activite enzymatique.
CN1091315A (zh) *	1992-10-08	1994-08-31	E·R·斯奎布父子公司	血纤维蛋白封闭剂组合物及其使用方法
US5512169A (en) *	1992-12-30	1996-04-30	Dow Corning Corporation	Liquid column packing materials
US5503933A (en) *	1994-02-25	1996-04-02	Purdue Research Foundation	Covalently bonded coatings
US5691152A (en) *	1995-11-09	1997-11-25	E. R. Squibb & Sons, Inc.	Stable avidin composition
EP1255603A1 (de) *	2000-02-09	2002-11-13	RESQ Lab B.V.	Packungsmaterial für die trennung von biomolekülen
US6638728B1 (en) *	2000-06-16	2003-10-28	Pierce Biotechnology, Inc.	Coated surfaces with high capacity for capturing target molecules
AU2003233498A1 (en) *	2002-06-10	2003-12-22	Phynexus, Inc.	Biomolecule open channel solid phase extraction systems and methods
US20040224329A1 (en) *	2003-05-08	2004-11-11	Gjerde Douglas T.	Three-dimensional solid phase extraction surfaces
US20040224425A1 (en) *	2003-05-08	2004-11-11	Gjerde Douglas T.	Biomolecule open channel solid phase extraction systems and methods
KR100988321B1 (ko) *	2003-07-26	2010-10-18	포항공과대학교 산학협력단	쿠커비투릴을 포함하는 고분자, 이를 이용한 정지상 및 컬럼
DE102008050588A1 (de)	2008-10-09	2010-04-15	Martin-Luther-Universität Halle-Wittenberg	Monolithische Säule mit immobilisiertem monomeren Avidin zur Anreicherung und Identifizierung biotinylierter Spezies
CN111936230A (zh) *	2018-01-12	2020-11-13	株式会社钟化	具有氨基的配体的固定化方法
CN114371243A (zh) *	2021-12-28	2022-04-19	湖南中晟全肽生化有限公司	一种d-生物素的HPLC检测方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4382124B1 (en) *	1958-07-18	1994-10-04	Rohm & Haas	Process for preparing macroreticular resins, copolymers and products of said process
DE2603319C3 (de) *	1976-01-29	1979-08-23	Boehringer Mannheim Gmbh, 6800 Mannheim	Verfahren zur Fixierung von biologisch aktiven Proteinen an Trägern
US4656252A (en) *	1980-01-24	1987-04-07	Giese Roger W	Amidobiotin compounds useful in a avidin-biotin multiple layering process
IL65131A0 (en) *	1982-02-28	1982-04-30	Yeda Res & Dev	Process for the production of agarose-polyaldehyde beads and their biological applications
US4582810A (en) *	1983-09-30	1986-04-15	Becton, Dickinson And Company	Immuno-agglutination particle suspensions
US4687820A (en) *	1984-08-22	1987-08-18	Cuno Incorporated	Modified polypeptide supports
FR2571498B1 (fr) *	1984-10-04	1988-04-08	Immunotech Sa	Procede de separation de cellules utilisant des anticorps et des billes de faible densite
US4874813A (en) *	1987-02-09	1989-10-17	Shannessy Daniel J O	Proteins bound to a marker or solid phase support matrix using a hydrazone linkage
CA1320718C (en) *	1987-06-08	1993-07-27	Richard Frederick Hammen	Chromatographic material
JPH0819010B2 (ja) *	1987-06-24	1996-02-28	エーザイ株式会社	光学異性体用分離剤
NL8701915A (nl) *	1987-08-14	1989-03-01	Waander Riethorst	Adsorbensmateriaal en toepassing daarvan voor het isoleren van stollingsfaktoren.

1990
- 1990-09-17 AT AT90310154T patent/ATE102074T1/de active
- 1990-09-17 DE DE69007006T patent/DE69007006T2/de not_active Expired - Fee Related
- 1990-09-17 CA CA002025487A patent/CA2025487A1/en not_active Abandoned
- 1990-09-17 DK DK90310154.1T patent/DK0423938T3/da active
- 1990-09-17 ES ES90310154T patent/ES2062394T3/es not_active Expired - Lifetime
- 1990-09-17 EP EP90310154A patent/EP0423938B1/de not_active Expired - Lifetime
- 1990-09-25 IL IL9577290A patent/IL95772A/en not_active IP Right Cessation
- 1990-09-25 NO NO904160A patent/NO180558C/no unknown
- 1990-09-26 EG EG56990A patent/EG19353A/xx active
- 1990-09-26 ZA ZA907678A patent/ZA907678B/xx unknown
- 1990-09-27 TR TR90/0904A patent/TR26082A/xx unknown
- 1990-09-27 NZ NZ235480A patent/NZ235480A/xx unknown
- 1990-09-27 BR BR909004848A patent/BR9004848A/pt not_active Application Discontinuation
- 1990-09-28 JP JP2260346A patent/JPH03197500A/ja active Pending
- 1990-09-28 PT PT95468A patent/PT95468B/pt not_active IP Right Cessation
- 1990-09-28 PL PL28710290A patent/PL287102A1/xx unknown
- 1990-09-28 KR KR1019900015425A patent/KR910006320A/ko not_active Ceased
1991
- 1991-05-16 US US07/702,433 patent/US5276062A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE69007006D1 (de)	1994-04-07
DK0423938T3 (da)	1994-03-28
CA2025487A1 (en)	1991-03-30
DE69007006T2 (de)	1994-08-25
AU6314390A (en)	1991-04-11
JPH03197500A (ja)	1991-08-28
IL95772A (en)	1995-05-26
NO904160L (no)	1991-04-02
NZ235480A (en)	1992-12-23
PT95468A (pt)	1991-05-22
AU629692B2 (en)	1992-10-08
NO180558B (no)	1997-01-27
ZA907678B (en)	1991-06-26
TR26082A (tr)	1994-12-15
ATE102074T1 (de)	1994-03-15
KR910006320A (ko)	1991-04-29
PT95468B (pt)	1997-07-31
BR9004848A (pt)	1991-09-10
EP0423938B1 (de)	1994-03-02
EP0423938A1 (de)	1991-04-24
IL95772A0 (en)	1991-06-30
NO180558C (no)	1997-05-07
US5276062A (en)	1994-01-04
NO904160D0 (no)	1990-09-25
ES2062394T3 (es)	1994-12-16
PL287102A1 (en)	1991-07-29

Publication	Publication Date	Title
ZA907678B (en)	1991-06-26	Ligand-containing medium for chromatographic separation,process for preparing the medium,and use of the medium for isolating synthetic or natural molecules from a fluid mixture
Banerjee et al.	1990	Increased microtubule assembly in bovine brain tubulin lacking the type III isotype of beta-tubulin.
CA2128208A1 (en)	1994-06-09	Novel seven transmembrane receptors
NO913186D0 (no)	1991-08-15	Fremgangsmaate for anvendelse og syntese av peptider.
EP1555328A3 (de)	2009-05-06	Siebtestverfahren für Genbanken (recombinant libraries)
ATE522610T1 (de)	2011-09-15	Menschliche, metabotrope glutamatrezeptor- subtypen (hmr6) und verwandte dns-verbindungen
ATE129347T1 (de)	1995-11-15	Biologisch aktive reagenzien aus carboxylgruppenhaltigen polymerisaten, analytisches element und verfahren zur verwendung.
SE8300693L (sv)	1984-08-10	Sett att framstella och isolera proteiner och polypeptider samt en hybridvektor for detta
WO1991008298A3 (en)	1991-10-17	Fusion proteins consisting of a ligand binding protein and a stable plasma protein
EP0496473A3 (en)	1993-01-13	Method of preparing biologically active reagents from succinimide-containing polymers, analytical element and methods of use
Sada et al.	1986	Adsorption equilibrium in immuno‐affinity chromatography with polyclonal and monoclonal antibodies
EP0992584A3 (de)	2000-06-07	Gereinigte Säugetier FLT3 Liganden und deren Agonisten und Antagonisten
DE69822767D1 (de)	2004-05-06	Verfahren zur Gastrennung durch Adsorption mit variabler Produktionsrate
WO1989010786A3 (en)	1990-03-08	Process for forming and using microdroplets
DE69623746D1 (de)	2002-10-24	Icam-4 material und verfahren
CA2491125A1 (en)	2004-01-15	Purification methods
WO1991015582A3 (en)	1991-12-12	Purified rap gaps, rap gap sequences, and uses thereof
Haase	1995	HPLC avidin monomer affinity resin
DE69421086D1 (de)	1999-11-11	Herstellung und anwendung von polypeptiden, die durch bindmolekuele markiert sind
JPS63145961A (ja)	1988-06-18	固相結合試薬、その製造方法及びそれを含有する検定用キット
AU629692C (en)	1993-09-09	Ligand-containing medium for chromatographic separation, process for preparing the medium, and use of the medium for isolating synthetic or natural molecules from a fluid mixture
SG58794G (en)	1994-10-14	Ligand-containing medium for chromatographic separation, process for preparing the medium and use of the medium for isolating synthetic or natural molecules from a fluid mixture.