EG19551A - Process for preparing of diastereoisomeric tetrahydropyrido (2,3-d) pyrimidine derivatives - Google Patents

Process for preparing of diastereoisomeric tetrahydropyrido (2,3-d) pyrimidine derivatives

Info

Publication number
EG19551A
EG19551A EG26087A EG26087A EG19551A EG 19551 A EG19551 A EG 19551A EG 26087 A EG26087 A EG 26087A EG 26087 A EG26087 A EG 26087A EG 19551 A EG19551 A EG 19551A
Authority
EG
Egypt
Prior art keywords
tetrahydropyrido
diastereoisomeric
preparing
pyrimidine derivatives
pyrimidine
Prior art date
Application number
EG26087A
Other languages
English (en)
Inventor
Edward C Taylor
Original Assignee
Univ Princeton
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Princeton filed Critical Univ Princeton
Application granted granted Critical
Publication of EG19551A publication Critical patent/EG19551A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EG26087A 1986-06-06 1987-05-04 Process for preparing of diastereoisomeric tetrahydropyrido (2,3-d) pyrimidine derivatives EG19551A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87153986A 1986-06-06 1986-06-06

Publications (1)

Publication Number Publication Date
EG19551A true EG19551A (en) 1996-02-29

Family

ID=25357673

Family Applications (1)

Application Number Title Priority Date Filing Date
EG26087A EG19551A (en) 1986-06-06 1987-05-04 Process for preparing of diastereoisomeric tetrahydropyrido (2,3-d) pyrimidine derivatives

Country Status (15)

Country Link
EP (1) EP0248573A3 (fr)
JP (1) JPH07116190B2 (fr)
KR (1) KR950004894B1 (fr)
CN (1) CN1019391B (fr)
AU (1) AU592182B2 (fr)
CA (1) CA1301155C (fr)
DK (1) DK170023B1 (fr)
EG (1) EG19551A (fr)
ES (1) ES2003828A6 (fr)
GR (1) GR870783B (fr)
NZ (1) NZ219971A (fr)
PH (1) PH25509A (fr)
PT (1) PT84990B (fr)
SU (1) SU1627087A3 (fr)
ZA (1) ZA873083B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE60038B1 (en) * 1986-06-30 1994-05-18 Univ Princeton 4(3H)-oxo-5, 6, 7, 8-tetrahydropyrido-[2, 3-d]pyrimidine derivatives
GB8625019D0 (en) * 1986-10-18 1986-11-19 Wellcome Found Compounds
US4895946A (en) * 1987-10-26 1990-01-23 The Trustees Of Princeton University Process for the preparation of fused pyridine compounds
US4889859A (en) * 1988-02-05 1989-12-26 The Trustees Of Princeton University Pyrido[2,3-d]pyrimidine derivatives
JP2830008B2 (ja) * 1988-04-01 1998-12-02 武田薬品工業株式会社 縮合ピリミジン誘導体
US5223620A (en) * 1988-04-01 1993-06-29 Takeda Chemical Industries, Ltd. Pyrido[2,3-d]pyrimidine compounds useful as intermediates
DK172753B1 (da) * 1988-05-25 1999-06-28 Lilly Co Eli N-(5,6,7,8-tetrahydropyrido[2,3--d]pyrimidin-6-yl-alkanoyl)-glutaminsyrederivater, deres anvendelse, farmaceutiske præparat
US5008391A (en) * 1989-07-07 1991-04-16 Eli Lilly And Company Enantioselective synthesis of antifolates
US5066828A (en) * 1990-04-12 1991-11-19 Merrell Dow Pharmaceuticals Inc. Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
JPH0873461A (ja) * 1994-09-06 1996-03-19 Yakult Honsha Co Ltd 新規なカンプトテシン誘導体、その製造法および抗腫瘍剤
WO1999041230A1 (fr) * 1998-02-11 1999-08-19 Eli Lilly And Company Procedes et intermediaires utiles pour la fabrication d'antifoliques
CN110749692B (zh) * 2019-10-15 2022-03-18 扬子江药业集团有限公司 L-谷氨酸二乙酯盐酸盐及其光学异构体的分离检测方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA861235B (en) * 1985-03-08 1986-10-29 Univ Princeton Pyrido(2,3-d)pyrimidine derivatives

Also Published As

Publication number Publication date
DK232387D0 (da) 1987-05-06
EP0248573A2 (fr) 1987-12-09
JPS6339878A (ja) 1988-02-20
DK170023B1 (da) 1995-05-01
AU592182B2 (en) 1990-01-04
DK232387A (da) 1987-12-07
KR880000431A (ko) 1988-03-25
PT84990B (pt) 1990-03-08
CN87104103A (zh) 1987-12-30
SU1627087A3 (ru) 1991-02-07
ES2003828A6 (es) 1988-11-16
ZA873083B (en) 1987-10-26
CN1019391B (zh) 1992-12-09
JPH07116190B2 (ja) 1995-12-13
GR870783B (en) 1987-09-25
CA1301155C (fr) 1992-05-19
EP0248573A3 (fr) 1989-06-14
PH25509A (en) 1991-07-24
PT84990A (en) 1987-07-01
KR950004894B1 (ko) 1995-05-15
AU7273187A (en) 1987-12-10
NZ219971A (en) 1989-08-29

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