EG24562A - 3-Z-[1-(4-(n-((4-methyl-piperazin-1-yl)-methylcarbonyl)-n-methyl-amino)anilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone-monoethanesulphonate and the use thereof as a pharmaceutical composition - Google Patents

3-Z-[1-(4-(n-((4-methyl-piperazin-1-yl)-methylcarbonyl)-n-methyl-amino)anilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone-monoethanesulphonate and the use thereof as a pharmaceutical composition

Info

Publication number
EG24562A
EG24562A EG2003070712A EG2003070712A EG24562A EG 24562 A EG24562 A EG 24562A EG 2003070712 A EG2003070712 A EG 2003070712A EG 2003070712 A EG2003070712 A EG 2003070712A EG 24562 A EG24562 A EG 24562A
Authority
EG
Egypt
Prior art keywords
methyl
monoethanesulphonate
indolinone
methylcarbonyl
anilino
Prior art date
Application number
EG2003070712A
Other languages
English (en)
Inventor
Gerald J Roth
Peter Sieger
Guenter Linz
Werner Rall
Frank Hilberg
Thomas Bock
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=30469050&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EG24562(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Application granted granted Critical
Publication of EG24562A publication Critical patent/EG24562A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
EG2003070712A 2002-07-24 2003-07-22 3-Z-[1-(4-(n-((4-methyl-piperazin-1-yl)-methylcarbonyl)-n-methyl-amino)anilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone-monoethanesulphonate and the use thereof as a pharmaceutical composition EG24562A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10233500A DE10233500A1 (de) 2002-07-24 2002-07-24 3-Z-[1-(4-(N-((4-Methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylen]-6-methoxycarbonyl-2-indolinon-Monoethansulfonat und dessen Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
EG24562A true EG24562A (en) 2009-10-25

Family

ID=30469050

Family Applications (1)

Application Number Title Priority Date Filing Date
EG2003070712A EG24562A (en) 2002-07-24 2003-07-22 3-Z-[1-(4-(n-((4-methyl-piperazin-1-yl)-methylcarbonyl)-n-methyl-amino)anilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone-monoethanesulphonate and the use thereof as a pharmaceutical composition

Country Status (35)

Country Link
US (2) US7119093B2 (da)
EP (2) EP1527047B1 (da)
JP (1) JP5039279B2 (da)
KR (1) KR101145691B1 (da)
CN (1) CN100351235C (da)
AR (2) AR040662A1 (da)
AT (1) ATE551322T1 (da)
AU (1) AU2003254376B2 (da)
BR (1) BRPI0312811B8 (da)
CA (1) CA2493310C (da)
CY (1) CY1112916T1 (da)
DE (1) DE10233500A1 (da)
DK (1) DK1527047T3 (da)
EA (1) EA008684B1 (da)
EC (1) ECSP055571A (da)
EG (1) EG24562A (da)
ES (1) ES2384968T3 (da)
HR (1) HRP20050070B1 (da)
IL (2) IL166405A0 (da)
ME (1) ME00353B (da)
MX (1) MXPA04012785A (da)
MY (1) MY136883A (da)
NO (1) NO330486B1 (da)
NZ (1) NZ538367A (da)
PE (1) PE20040704A1 (da)
PL (1) PL223758B1 (da)
PT (1) PT1527047E (da)
RS (1) RS52283B (da)
SA (1) SA03240446B1 (da)
SI (1) SI1527047T1 (da)
TW (1) TWI285635B (da)
UA (1) UA78352C2 (da)
UY (1) UY27904A1 (da)
WO (1) WO2004013099A1 (da)
ZA (1) ZA200409814B (da)

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Publication number Publication date
BRPI0312811A8 (pt) 2019-01-02
CA2493310C (en) 2011-01-18
PT1527047E (pt) 2012-06-28
AU2003254376A1 (en) 2004-02-23
ES2384968T3 (es) 2012-07-16
CY1112916T1 (el) 2016-04-13
ME00353B (me) 2011-10-10
TWI285635B (en) 2007-08-21
JP2005535684A (ja) 2005-11-24
PL223758B1 (pl) 2016-10-31
ZA200409814B (en) 2006-02-22
US7119093B2 (en) 2006-10-10
DE10233500A1 (de) 2004-02-19
AR040662A1 (es) 2005-04-13
EP1527047B1 (en) 2012-03-28
UY27904A1 (es) 2004-02-27
NZ538367A (en) 2008-01-31
EP1527047A1 (en) 2005-05-04
US20060258681A1 (en) 2006-11-16
US20040176392A1 (en) 2004-09-09
MEP53708A (en) 2011-05-10
EP2386543A1 (en) 2011-11-16
JP5039279B2 (ja) 2012-10-03
PE20040704A1 (es) 2004-11-29
TW200409754A (en) 2004-06-16
SA03240446B1 (ar) 2007-07-31
RS20050046A (sr) 2007-09-21
AU2003254376B2 (en) 2010-06-17
CN100351235C (zh) 2007-11-28
IL166405A (en) 2009-11-18
BRPI0312811B1 (pt) 2019-03-12
SI1527047T1 (sl) 2012-07-31
MXPA04012785A (es) 2005-06-08
RS52283B (sr) 2012-10-31
EA200500146A1 (ru) 2005-08-25
IL166405A0 (en) 2006-01-15
DK1527047T3 (da) 2012-07-16
MY136883A (en) 2008-11-28
BRPI0312811B8 (pt) 2021-05-25
PL372996A1 (en) 2005-08-08
WO2004013099A1 (en) 2004-02-12
ECSP055571A (es) 2005-04-18
ATE551322T1 (de) 2012-04-15
KR20050042139A (ko) 2005-05-04
HRP20050070B1 (hr) 2013-09-30
HRP20050070A2 (en) 2005-12-31
KR101145691B1 (ko) 2012-05-25
AR094217A2 (es) 2015-07-15
CN1671660A (zh) 2005-09-21
HK1078851A1 (zh) 2006-03-24
BR0312811A (pt) 2005-04-19
CA2493310A1 (en) 2004-02-12
UA78352C2 (uk) 2007-03-15
NO20050985L (no) 2005-02-23
NO330486B1 (no) 2011-04-26
EA008684B1 (ru) 2007-06-29

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