EG25699A - N-aryl piperidine substituted biphenylcarboxamides - Google Patents

N-aryl piperidine substituted biphenylcarboxamides

Info

Publication number: EG25699A
Authority: EG; Egypt
Prior art keywords: piperidine substituted; aryl piperidine; biphenylcarboxamides; substituted biphenylcarboxamides; aryl
Prior art date: 2002-08-12

Application number

EG2003080749A

Other languages

English (en)

Inventor

Lieven Meerpoel

Leo Jacobus Jozef Backx

Peter Walter Maria Roevens

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-08-12

Filing date

2003-08-02

Publication date

2012-05-22

2003-08-02 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2012-05-22 Application granted granted Critical

2012-05-22 Publication of EG25699A publication Critical patent/EG25699A/xx

Links

GTKIGDZXPDCIKR-UHFFFAOYSA-N 2-phenylbenzamide Chemical class NC(=O)C1=CC=CC=C1C1=CC=CC=C1 GTKIGDZXPDCIKR-UHFFFAOYSA-N 0.000 title 1
NQRYJNQNLNOLGT-UHFFFAOYSA-N tetrahydropyridine hydrochloride Natural products C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Diabetes (AREA)
Obesity (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Child & Adolescent Psychology (AREA)
Vascular Medicine (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)

EG2003080749A 2002-08-12 2003-08-02 N-aryl piperidine substituted biphenylcarboxamides EG25699A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP02078309		2002-08-12

Publications (1)

Publication Number	Publication Date
EG25699A true EG25699A (en)	2012-05-22

Family

ID=31896911

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EG2003080749A EG25699A (en)	2002-08-12	2003-08-02	N-aryl piperidine substituted biphenylcarboxamides

Country Status (31)

Country	Link
US (2)	US20060040989A1 (is)
EP (1)	EP1536796B1 (is)
JP (1)	JP4559856B2 (is)
KR (1)	KR101052204B1 (is)
CN (3)	CN101165053A (is)
AR (1)	AR040968A1 (is)
AT (1)	ATE385796T1 (is)
AU (1)	AU2003250215B2 (is)
BR (1)	BR0313377A (is)
CA (1)	CA2494208C (is)
CY (1)	CY1107945T1 (is)
DE (1)	DE60319097T2 (is)
DK (1)	DK1536796T3 (is)
EA (1)	EA008061B1 (is)
EG (1)	EG25699A (is)
ES (1)	ES2301873T3 (is)
HR (1)	HRP20050103B1 (is)
IL (1)	IL166795A (is)
IS (1)	IS2726B (is)
MX (1)	MXPA05001712A (is)
MY (1)	MY136632A (is)
NO (1)	NO329308B1 (is)
NZ (1)	NZ538680A (is)
PA (1)	PA8579901A1 (is)
PL (1)	PL212405B1 (is)
PT (1)	PT1536796E (is)
SI (1)	SI1536796T1 (is)
TW (1)	TWI342775B (is)
UA (1)	UA79300C2 (is)
WO (1)	WO2004017969A1 (is)
ZA (1)	ZA200501225B (is)

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US8183239B2 (en)	2005-10-31	2012-05-22	Janssen Pharmaceutica Nv	Substituted piperazines and piperidines as modulators of the neuropeptide Y2 receptor
CA3042781C (en)	2006-04-03	2021-10-19	Roche Innovation Center Copenhagen A/S	Pharmaceutical composition comprising anti-mirna antisense oligonucleotides
EA201100811A1 (ru) *	2006-04-03	2012-06-29	Сантарис Фарма А/С	Фармацевтическая композиция
US20080249130A1 (en) *	2007-02-09	2008-10-09	Sirtris Pharmaceuticals, Inc.	Gut microsomal triglyceride transport protein inhibitors
US8580756B2 (en) *	2007-03-22	2013-11-12	Santaris Pharma A/S	Short oligomer antagonist compounds for the modulation of target mRNA
US8470791B2 (en) *	2007-03-22	2013-06-25	Santaris Pharma A/S	RNA antagonist compounds for the inhibition of Apo-B100 expression
US20110054011A1 (en) *	2007-08-30	2011-03-03	Mccullagh Keith	RNA Antagonist Compounds for the Modulation of FABP4/AP2
ATE505454T1 (de) *	2007-09-20	2011-04-15	Amgen Inc	1-(4-(4-benzylbenzamid)-benzyl)-azetidin-3- carboxylsäurederivate und entsprechende verbindungen als s1p-rezeptor-modulatoren zur behandlung von immunerkrankungen
DK2205737T3 (da) *	2007-10-04	2013-05-21	Santaris Pharma As	Mikromirer
EP2268811A1 (en) *	2008-03-07	2011-01-05	Santaris Pharma A/S	Pharmaceutical compositions for treatment of microrna related diseases
US8492357B2 (en)	2008-08-01	2013-07-23	Santaris Pharma A/S	Micro-RNA mediated modulation of colony stimulating factors
US9034837B2 (en) *	2009-04-24	2015-05-19	Roche Innovation Center Copenhagen A/S	Pharmaceutical compositions for treatment of HCV patients that are poor-responders to interferon
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MX367083B (es)	2013-06-27	2019-08-05	Roche Innovation Ct Copenhagen As	Oligomeros antisentido y conjugados con diana en la proteina-convertasa subtilisina/kexina tipo 9(pcsk9).
JP6594351B2 (ja)	2014-06-16	2019-10-23	ジョンソン、マッセイ、パブリック、リミテッド、カンパニー	新規中間体を含むアルキル化アリールピペラジン及びアルキル化アリールピペリジン化合物の製造方法

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GB0129015D0 (en) *	2001-12-04	2002-01-23	Glaxo Group Ltd	Compounds

2003
- 2003-05-08 UA UAA200501990A patent/UA79300C2/uk unknown
- 2003-08-02 EG EG2003080749A patent/EG25699A/xx active
- 2003-08-05 AU AU2003250215A patent/AU2003250215B2/en not_active Ceased
- 2003-08-05 DK DK03792260T patent/DK1536796T3/da active
- 2003-08-05 NZ NZ538680A patent/NZ538680A/en not_active IP Right Cessation
- 2003-08-05 SI SI200331203T patent/SI1536796T1/sl unknown
- 2003-08-05 US US10/524,051 patent/US20060040989A1/en not_active Abandoned
- 2003-08-05 KR KR1020057000829A patent/KR101052204B1/ko not_active Expired - Fee Related
- 2003-08-05 ES ES03792260T patent/ES2301873T3/es not_active Expired - Lifetime
- 2003-08-05 CA CA2494208A patent/CA2494208C/en not_active Expired - Fee Related
- 2003-08-05 EP EP03792260A patent/EP1536796B1/en not_active Expired - Lifetime
- 2003-08-05 MX MXPA05001712A patent/MXPA05001712A/es active IP Right Grant
- 2003-08-05 PL PL373379A patent/PL212405B1/pl unknown
- 2003-08-05 EA EA200500348A patent/EA008061B1/ru not_active IP Right Cessation
- 2003-08-05 PT PT03792260T patent/PT1536796E/pt unknown
- 2003-08-05 CN CNA2007101866745A patent/CN101165053A/zh active Pending
- 2003-08-05 BR BR0313377-0A patent/BR0313377A/pt not_active Application Discontinuation
- 2003-08-05 AT AT03792260T patent/ATE385796T1/de active
- 2003-08-05 HR HRP20050103AA patent/HRP20050103B1/hr not_active IP Right Cessation
- 2003-08-05 WO PCT/EP2003/008694 patent/WO2004017969A1/en not_active Ceased
- 2003-08-05 JP JP2004530089A patent/JP4559856B2/ja not_active Expired - Fee Related
- 2003-08-05 CN CNB03818592XA patent/CN100366252C/zh not_active Expired - Fee Related
- 2003-08-05 DE DE60319097T patent/DE60319097T2/de not_active Expired - Lifetime
- 2003-08-05 CN CN2007101866730A patent/CN101165052B/zh not_active Expired - Fee Related
- 2003-08-07 PA PA20038579901A patent/PA8579901A1/es unknown
- 2003-08-08 MY MYPI20033022A patent/MY136632A/en unknown
- 2003-08-11 TW TW092121938A patent/TWI342775B/zh not_active IP Right Cessation
- 2003-08-11 AR ARP030102901A patent/AR040968A1/es not_active Application Discontinuation
2004
- 2004-12-29 IS IS7622A patent/IS2726B/is unknown
2005
- 2005-01-31 NO NO20050563A patent/NO329308B1/no not_active IP Right Cessation
- 2005-02-10 IL IL166795A patent/IL166795A/en unknown
- 2005-02-10 ZA ZA200501225A patent/ZA200501225B/en unknown
2008
- 2008-05-13 CY CY20081100504T patent/CY1107945T1/el unknown
2009
- 2009-01-09 US US12/351,385 patent/US8258304B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
PL373379A1 (en)	2005-08-22
ES2301873T3 (es)	2008-07-01
HRP20050103A2 (en)	2006-09-30
PT1536796E (pt)	2008-05-13
CA2494208C (en)	2011-05-10
JP2006500371A (ja)	2006-01-05
IL166795A0 (en)	2006-01-15
WO2004017969A1 (en)	2004-03-04
HRP20050103B1 (hr)	2013-09-30
IS7622A (is)	2004-12-29
PL212405B1 (pl)	2012-09-28
CN101165052A (zh)	2008-04-23
DE60319097T2 (de)	2009-06-04
AR040968A1 (es)	2005-04-27
ZA200501225B (en)	2006-07-26
CN101165052B (zh)	2012-04-18
CY1107945T1 (el)	2013-09-04
UA79300C2 (en)	2007-06-11
NZ538680A (en)	2006-01-27
CN1674900A (zh)	2005-09-28
AU2003250215A1 (en)	2004-03-11
HK1083451A1 (en)	2006-07-07
IL166795A (en)	2010-11-30
EP1536796B1 (en)	2008-02-13
MY136632A (en)	2008-11-28
BR0313377A (pt)	2005-07-12
US20090156623A1 (en)	2009-06-18
NO329308B1 (no)	2010-09-27
US8258304B2 (en)	2012-09-04
EA200500348A1 (ru)	2005-08-25
ATE385796T1 (de)	2008-03-15
NO20050563L (no)	2005-01-31
CN100366252C (zh)	2008-02-06
CA2494208A1 (en)	2004-03-04
CN101165053A (zh)	2008-04-23
KR20050026483A (ko)	2005-03-15
TW200412954A (en)	2004-08-01
JP4559856B2 (ja)	2010-10-13
EP1536796A1 (en)	2005-06-08
DK1536796T3 (da)	2008-06-09
MXPA05001712A (es)	2005-04-19
SI1536796T1 (sl)	2008-08-31
IS2726B (is)	2011-03-15
DE60319097D1 (de)	2008-03-27
PA8579901A1 (es)	2005-03-03
US20060040989A1 (en)	2006-02-23
EA008061B1 (ru)	2007-02-27
TWI342775B (en)	2011-06-01
KR101052204B1 (ko)	2011-07-29
AU2003250215B2 (en)	2009-01-22

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