EP0055251A1 - Zusammensetzungen zum entkalken und reinigen von gebissen - Google Patents
Zusammensetzungen zum entkalken und reinigen von gebissenInfo
- Publication number
- EP0055251A1 EP0055251A1 EP19810900204 EP81900204A EP0055251A1 EP 0055251 A1 EP0055251 A1 EP 0055251A1 EP 19810900204 EP19810900204 EP 19810900204 EP 81900204 A EP81900204 A EP 81900204A EP 0055251 A1 EP0055251 A1 EP 0055251A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- citric acid
- composition
- sodium bicarbonate
- dentures
- calcium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000002360 preparation method Methods 0.000 title description 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract description 91
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims abstract description 40
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims abstract description 20
- 235000017557 sodium bicarbonate Nutrition 0.000 claims abstract description 20
- 238000000034 method Methods 0.000 claims abstract description 13
- 239000000758 substrate Substances 0.000 claims abstract description 8
- 208000004434 Calcinosis Diseases 0.000 claims abstract description 7
- 150000001875 compounds Chemical class 0.000 claims abstract description 7
- 235000015165 citric acid Nutrition 0.000 claims description 29
- 239000000203 mixture Substances 0.000 claims description 28
- 229960004106 citric acid Drugs 0.000 claims description 25
- 125000003118 aryl group Chemical group 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 4
- 229960004543 anhydrous citric acid Drugs 0.000 claims description 3
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims 2
- KKEBXNMGHUCPEZ-UHFFFAOYSA-N 4-phenyl-1-(2-sulfanylethyl)imidazolidin-2-one Chemical compound N1C(=O)N(CCS)CC1C1=CC=CC=C1 KKEBXNMGHUCPEZ-UHFFFAOYSA-N 0.000 claims 1
- 239000000049 pigment Substances 0.000 claims 1
- 229910000029 sodium carbonate Inorganic materials 0.000 claims 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric Acid Chemical compound [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 abstract description 7
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 abstract description 5
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 abstract description 5
- FEWJPZIEWOKRBE-XIXRPRMCSA-N Mesotartaric acid Chemical compound OC(=O)[C@@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-XIXRPRMCSA-N 0.000 abstract 1
- 238000004140 cleaning Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 12
- 238000006243 chemical reaction Methods 0.000 description 11
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 8
- 239000000292 calcium oxide Substances 0.000 description 7
- ODINCKMPIJJUCX-UHFFFAOYSA-N calcium oxide Inorganic materials [Ca]=O ODINCKMPIJJUCX-UHFFFAOYSA-N 0.000 description 7
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 6
- 229930006000 Sucrose Natural products 0.000 description 6
- 239000005720 sucrose Substances 0.000 description 6
- 239000011575 calcium Substances 0.000 description 5
- 238000004040 coloring Methods 0.000 description 5
- 125000000896 monocarboxylic acid group Chemical group 0.000 description 5
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 4
- 235000016257 Mentha pulegium Nutrition 0.000 description 4
- 244000246386 Mentha pulegium Species 0.000 description 4
- 235000004357 Mentha x piperita Nutrition 0.000 description 4
- 239000002253 acid Substances 0.000 description 4
- 229910000019 calcium carbonate Inorganic materials 0.000 description 4
- BRPQOXSCLDDYGP-UHFFFAOYSA-N calcium oxide Chemical compound [O-2].[Ca+2] BRPQOXSCLDDYGP-UHFFFAOYSA-N 0.000 description 4
- 235000001050 hortel pimenta Nutrition 0.000 description 4
- 150000001261 hydroxy acids Chemical class 0.000 description 4
- 239000001630 malic acid Substances 0.000 description 4
- 235000011090 malic acid Nutrition 0.000 description 4
- 235000002906 tartaric acid Nutrition 0.000 description 4
- 239000011975 tartaric acid Substances 0.000 description 4
- 150000007513 acids Chemical class 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- FNAQSUUGMSOBHW-UHFFFAOYSA-H calcium citrate Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O FNAQSUUGMSOBHW-UHFFFAOYSA-H 0.000 description 3
- 239000001354 calcium citrate Substances 0.000 description 3
- 229910002092 carbon dioxide Inorganic materials 0.000 description 3
- 235000013337 tricalcium citrate Nutrition 0.000 description 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- OLOZVPHKXALCRI-UHFFFAOYSA-L calcium malate Chemical compound [Ca+2].[O-]C(=O)C(O)CC([O-])=O OLOZVPHKXALCRI-UHFFFAOYSA-L 0.000 description 2
- 239000001362 calcium malate Substances 0.000 description 2
- 229940016114 calcium malate Drugs 0.000 description 2
- 235000011038 calcium malates Nutrition 0.000 description 2
- GUPPESBEIQALOS-UHFFFAOYSA-L calcium tartrate Chemical compound [Ca+2].[O-]C(=O)C(O)C(O)C([O-])=O GUPPESBEIQALOS-UHFFFAOYSA-L 0.000 description 2
- 239000001427 calcium tartrate Substances 0.000 description 2
- 235000011035 calcium tartrate Nutrition 0.000 description 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 235000013311 vegetables Nutrition 0.000 description 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 description 1
- 239000004135 Bone phosphate Substances 0.000 description 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 1
- 235000008733 Citrus aurantifolia Nutrition 0.000 description 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
- 235000011941 Tilia x europaea Nutrition 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 150000001447 alkali salts Chemical class 0.000 description 1
- 238000004061 bleaching Methods 0.000 description 1
- 238000007664 blowing Methods 0.000 description 1
- 159000000007 calcium salts Chemical class 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 239000002781 deodorant agent Substances 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000012456 homogeneous solution Substances 0.000 description 1
- 239000004571 lime Substances 0.000 description 1
- 230000010399 physical interaction Effects 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- CLJTZNIHUYFUMR-UHFFFAOYSA-M sodium;hydrogen carbonate;2-hydroxypropane-1,2,3-tricarboxylic acid Chemical compound [Na+].OC([O-])=O.OC(=O)CC(O)(C(O)=O)CC(O)=O CLJTZNIHUYFUMR-UHFFFAOYSA-M 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000003313 weakening effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
- A61Q11/02—Preparations for deodorising, bleaching or disinfecting dentures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/362—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/22—Gas releasing
- A61K2800/222—Effervescent
Definitions
- This invention relates to a preparation for decalcifying and cleansing dentures and other substrates having calcium deposits formed thereon. Hitherto dentures have been subjected to many different denture cleansing preparations but have met with little success.
- the method of the invention includes the step of applying to the dentures a compound selected from the group consisting of malic, tartaric, mesotartaric and citric acids so as to remove calcium deposits formed thereon.
- the denture cleansing preparation of the invention is a composition containing malic, tartaric, mesotartaric or citric acids.
- the composition also includes an alkali salt which is preferably sodium bicarbonate.
- the most preferred hydroxy acid which is used in relation to the present invention is citric acid because of its tribasic nature. While the other acids such as malic and tartaric may be used with good effectiveness, these acids are dibasic and as such will not prove as effective as citric acid.
- citric acid In relation to citric acid, it has been found in accordance with the invention that when it is combined with sodium bicarbonate there is provided a most effective composition for cleansing and decalcifying artificial dentures .
- Citric acid has the formula:
- sodium bicarbonate (Na HCO-,) ⁇ is useful as it promotes an effervescent action because it reacts with the citric acid to release carbon dioxide. This effervescent action helps in releasing food particles trapped in inaccessible locations within the mouth and breaks up tablets incorporating the composition of the 0 invention into a homogeneous solution.
- the hydroxy acid may be used per se but it is much preferred to use sodium bicarbonate in conjunction therewith for the reasons discussed above. 5 Also if hydrous citric acid (i.e. having one molecule of waterl is mixed with sodium bicarbonate initially, the resulting mixture f ses, due to physical interaction due to the water present which is provided by the water molecules in the hydrous citric acid. If the mixture is then dried, such as by blowing hot air there ⁇ through with simultaneous agitation of the particles in the mixture, a dry granular residue is obtained containing anhydrous citric acid.
- hydrous citric acid i.e. having one molecule of waterl
- the resulting mixture f ses, due to physical interaction due to the water present which is provided by the water molecules in the hydrous citric acid. If the mixture is then dried, such as by blowing hot air there ⁇ through with simultaneous agitation of the particles in the mixture, a dry granular residue is obtained containing anhydrous citric acid.
- anhydrous citric acid may be obtained commercially to which is added sodium bicarbonate plus other desired components. This latter procedure is preferable because it is not necessary to carry out the drying step referred to above.
- the mixture may be compressed and thus tablets may be formed by any suitable method known per se.
- the tablets are stable if stored in dry conditions. No chemical reaction will occur until water is mixed with the components of the mixture (i.e. citric acid and sodium bicarbonate) for the purpose of decalcification and cleansi of dentures. Then an effervescent reaction occurs with the subsequent rapid removal of the calculus from the artificial dentures.
- citric acid - sodium bicarbonate composition In relation to the preferred citric acid - sodium bicarbonate composition, other additives may be included such as colouring components and aromatic components.
- the composition contains a proportion of sodium bicarbonate of around 5 to 25%, based on the weight of the composition and 75 to 95% of citric acid. More suitably the composition comprises 80% citric acid, 15% sodium bicarbonate, 4% of colouring matter and 1% of aromatic material. All these proportions are calculated on a weight basis.
- EXAMPLE In one example of the invention , a composition comprising 24.8g. of citric acid, 4.65g. of sodium bicarbonate, 1.24g. of colouring matter and 0.31g. of aromatic component was found to be useful.
- the citric acid neutralizes and decalcifies the calcium deposits while the effervescent effect provided by sodium bicarbonate helps activate the cleansing action of the citric acid and also remove food deposits.
- Colouring matter such as a vegetable dye help distinguish the cleansing composition from other types and also assists in covering up or disguising of debris liberated by the reaction taking place.
- the aromatic component such as peppermint provides a deodorant type of action.
- Hot water is much preferred to hot water for use in the invention as citric acid reacts more effective ⁇ ly in cold water. Also calcium citrate is less soluble in hot water than in cold water. Hot water also causes premature deterioration in the dentures such as bleaching and weakening of the acrylic material dentures are made from. In comparison with a conventional product which requires to be used every night, the composition of the invention only requires usage once a week. Used in this manner, the dentures will have little or no calculus formation and will be kept in a sterile condition.
- a preferred colouring material for use in the invention is prepared by mixing sucrose with a dye in combination with sodium bicarbonate and water. The mixture may be heated slowly and steam is evolved. The colour of dye is absorbed by the sucrose. Suggested proportions are sucrose (one ounce), dye (50mg.) and sodium bicarbonate 4.65g.
- a preferred dye is a vegetable dye such as G.B. Pillar-Box Red No. C931.
- a suitable aromatic additive may be prepared by mixing peppermint essence with sucrose and sodium bicarbonate. When heated to expell moisture, the sucrose absorbs the peppermint and bicarbonate to form granular crystals. Suggested proportions are sucrose (one ounce) , 3ml. of peppermint essence and 4.65g. of sodium bicarbonate
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
- Dental Preparations (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPE207480 | 1980-01-21 | ||
| AU2074/80 | 1980-01-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EP0055251A1 true EP0055251A1 (de) | 1982-07-07 |
Family
ID=3768411
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP19810900204 Withdrawn EP0055251A1 (de) | 1980-01-21 | 1981-01-14 | Zusammensetzungen zum entkalken und reinigen von gebissen |
Country Status (2)
| Country | Link |
|---|---|
| EP (1) | EP0055251A1 (de) |
| WO (1) | WO1981002102A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4547362A (en) * | 1983-03-14 | 1985-10-15 | Church & Dwight Co., Inc. | Sodium-bicarbonate-containing tooth powder |
| NL9101559A (nl) * | 1991-09-16 | 1993-04-16 | Dentip Int Bv | Toepassing van organische zuren voor het reinigen van gebitsprotheses alsmede preparaten, die dergelijke zuren bevatten. |
| DE19705930A1 (de) * | 1997-02-17 | 1998-08-20 | Kukident Gmbh | Gebißreinigungszusammensetzung |
| ES2712023A1 (es) * | 2017-11-06 | 2019-05-08 | Aguirre Ana Luisa Garcia | Compuesto y procedimiento para evitar y controlar la piorrea. |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1488315A (en) * | 1922-10-17 | 1924-03-25 | Howard S Clemmer | Cleanser for artificial teeth |
| DE1617744A1 (de) * | 1964-07-24 | 1970-09-10 | Peter Strong & Co Inc | Reinigungsmittel fuer Zahnprothesen |
| DE1617430C3 (de) * | 1966-07-29 | 1980-07-10 | Wuerttembergische Parfuemerie-Fabrik Gmbh, 7332 Eislingen | Schäumende lagerstabile Zahnpaste |
| AU1292370A (en) * | 1969-03-24 | 1971-09-30 | Monsanto Company | Improved effervescent compositions |
| FR2070147A1 (de) * | 1969-10-20 | 1971-09-10 | Warner Lambert Pharmaceutical | |
| US3937806A (en) * | 1970-07-06 | 1976-02-10 | The Procter & Gamble Company | Oral compositions for caries prophylaxis |
| DE2158943A1 (de) * | 1970-12-03 | 1972-06-29 | Scherico Ltd., Luzern (Schweiz) | Moussierende Zubereitungen |
| US3962417A (en) * | 1974-03-27 | 1976-06-08 | Howell Charles J | Dentifrice |
| US3962107A (en) * | 1974-06-24 | 1976-06-08 | Johnson & Johnson | Enzyme-containing denture cleanser tablet |
| GB1534261A (en) * | 1974-11-08 | 1978-11-29 | Reckitt & Colmann Prod Ltd | Cleaning composition |
| US4115293A (en) * | 1975-10-06 | 1978-09-19 | E. I. Du Pont De Nemours And Company | Denture cleanser |
| GB1492660A (en) * | 1975-10-13 | 1977-11-23 | Colgate Palmolive Co | Dentifrices |
| AU510235B2 (en) * | 1975-12-22 | 1980-06-19 | Johnson & Johnson | Denture cleanser tablet |
| US4105756A (en) * | 1976-11-24 | 1978-08-08 | Monsanto Company | Inhibition of dental calculus |
| US4130635A (en) * | 1976-11-22 | 1978-12-19 | Monsanto Company | Calculus inhibition |
| US4151271A (en) * | 1976-11-01 | 1979-04-24 | Monsanto Company | Oral compositions |
| CA1083048A (en) * | 1977-02-17 | 1980-08-05 | Herman J. Lutz | Citric acid and sodium citrate in dentifrice compositions |
| ZA785772B (en) * | 1978-10-13 | 1980-02-27 | Reckitt & Colman South Africa | Denture cleansing compositions |
-
1981
- 1981-01-14 EP EP19810900204 patent/EP0055251A1/de not_active Withdrawn
- 1981-01-14 WO PCT/AU1981/000005 patent/WO1981002102A1/en not_active Ceased
Non-Patent Citations (1)
| Title |
|---|
| See references of WO8102102A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO1981002102A1 (en) | 1981-08-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| AK | Designated contracting states |
Designated state(s): DE FR GB NL SE |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 19820706 |