EP0116629A4 - Grippe-antisera mit breitem spektrum. - Google Patents

Grippe-antisera mit breitem spektrum.

Info

Publication number
EP0116629A4
EP0116629A4 EP19830902869 EP83902869A EP0116629A4 EP 0116629 A4 EP0116629 A4 EP 0116629A4 EP 19830902869 EP19830902869 EP 19830902869 EP 83902869 A EP83902869 A EP 83902869A EP 0116629 A4 EP0116629 A4 EP 0116629A4
Authority
EP
European Patent Office
Prior art keywords
antisera
flu
wide spectrum
spectrum
wide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19830902869
Other languages
English (en)
French (fr)
Other versions
EP0116629A1 (de
Inventor
Nicola Green
Stephen Alexander
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Clinic and Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic and Research Foundation filed Critical Scripps Clinic and Research Foundation
Publication of EP0116629A1 publication Critical patent/EP0116629A1/de
Publication of EP0116629A4 publication Critical patent/EP0116629A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10RNA viruses
    • C07K16/108Orthomyxoviridae (F), e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16211Influenzavirus B, i.e. influenza B virus
    • C12N2760/16222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP19830902869 1982-08-23 1983-08-23 Grippe-antisera mit breitem spektrum. Withdrawn EP0116629A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41045582A 1982-08-23 1982-08-23
US410455 1982-08-23

Publications (2)

Publication Number Publication Date
EP0116629A1 EP0116629A1 (de) 1984-08-29
EP0116629A4 true EP0116629A4 (de) 1987-06-29

Family

ID=23624803

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19830902869 Withdrawn EP0116629A4 (de) 1982-08-23 1983-08-23 Grippe-antisera mit breitem spektrum.

Country Status (16)

Country Link
EP (1) EP0116629A4 (de)
JP (1) JPS59501714A (de)
KR (1) KR840006198A (de)
AU (1) AU570929B2 (de)
DK (1) DK203684A (de)
ES (1) ES525088A0 (de)
FI (1) FI841583A0 (de)
GR (1) GR78931B (de)
IL (1) IL69556A (de)
IT (1) IT1168636B (de)
NO (1) NO161002C (de)
NZ (2) NZ220612A (de)
PH (1) PH18872A (de)
PT (1) PT77230B (de)
WO (1) WO1984000687A1 (de)
ZA (1) ZA836080B (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR241713A1 (es) * 1984-08-30 1992-11-30 Smithkline Beckman Corp Molecula de dna con una secuencia de bases que codifica la proteina c13 y preparacion de vacunas contra la gripe.
US5866363A (en) 1985-08-28 1999-02-02 Pieczenik; George Method and means for sorting and identifying biological information
KR910700259A (ko) * 1989-01-12 1991-03-14 리차드 이. 림바크 T-세포 인지성 펩티드 변형에 의해 면역반응에 영향을 주는 방법
EP0621339B1 (de) * 1992-09-17 2001-10-24 Takara Shuzo Co. Ltd. Immunogene Polypeptide des menschlichen Influenza-A-Virus Haemagglutinin
JP2996864B2 (ja) * 1994-03-30 2000-01-11 寳酒造株式会社 抗体可変領域dna
US8148085B2 (en) 2006-05-15 2012-04-03 Sea Lane Biotechnologies, Llc Donor specific antibody libraries
JP2009537147A (ja) * 2006-05-15 2009-10-29 シー レーン バイオテクノロジーズ, エルエルシー インフルエンザウイルスに対する中和抗体
EP2059532B1 (de) * 2006-09-07 2012-12-26 Crucell Holland B.V. Humane bindungsmoleküle, die in der lage sind, das grippevirus h5n1 zu neutralisieren, und anwendungen davon
ITTO20070066A1 (it) 2007-01-30 2008-07-31 Pomona Biotechnologies Llc Anticorpi monoclonali anti-idiotipo mimotopi dell'antigene gp 120 di hiv
BRPI0809435A2 (pt) 2007-03-27 2014-09-09 Sea Lane Biotechnologies, Llc Constructos e bibliotecas que compreendem sequências de cadeia leve substituida de anticorpos
ITTO20080204A1 (it) 2008-03-17 2009-09-18 Pomona Biotechnologies Llc Anticorpi monoclonali atti a reagire con una pluralita di sottotipi del virus influenzale a
EP2274334A2 (de) 2008-03-28 2011-01-19 Sea Lane Biotechnologies,llc. Neutralisierende moleküle gegen virale antigene
ITTO20080398A1 (it) 2008-05-27 2009-11-28 Pomona Biotechnologies Llc Anticorpi monoclonali aventi proprieta' di cross-neutralizzazione omosubtipica per virus influenzali di tipo a sottotipo h1
ITTO20080964A1 (it) 2008-12-22 2010-06-23 Natimab Therapeutics S R L Anticorpo monoclonale anti-hcv come medicamento per il trattamento terapeutico e la prevenzione di infezioni da hcv
US8975378B2 (en) 2008-12-25 2015-03-10 Osaka University Human anti-human influenza virus antibody
JP2012521786A (ja) 2009-03-30 2012-09-20 モウント シナイ スクール オフ メディシネ インフルエンザウイルスワクチン及びその使用
JP2012526839A (ja) 2009-05-13 2012-11-01 シー レーン バイオテクノロジーズ, エルエルシー インフルエンザウイルスに対する中和分子
WO2010138564A1 (en) 2009-05-26 2010-12-02 Mount Sinai School Of Medicine Of New York University Monoclonal antibodies against influenza virus generated by cyclical administration and uses thereof
IT1395961B1 (it) 2009-06-01 2012-11-02 Pomona Biotechnologies Llc Anticorpi monoclonali come medicamento per il trattamento terapeutico e/o profilattico delle infezioni da virus influenzale a (h1n1) di origine suina (s-oiv)
US9701723B2 (en) * 2010-02-18 2017-07-11 Icahn School Of Medicine At Mount Sinai Vaccines for use in the prophylaxis and treatment of influenza virus disease
MX2012011300A (es) 2010-03-30 2012-11-29 Sinai School Medicine Vacunas del virus de influenza y usos de las mismas.
EP2736928B1 (de) 2011-07-28 2019-01-09 i2 Pharmaceuticals, Inc. Gegen erbb3-gerichtete sur-bindende proteine
HK1200102A1 (en) 2011-09-20 2015-07-31 西奈山医学院 Influenza virus vaccines and uses thereof
EP2793940B1 (de) 2011-12-22 2018-11-14 i2 Pharmaceuticals, Inc. Surrogatbindungsproteine
US9969794B2 (en) 2012-05-10 2018-05-15 Visterra, Inc. HA binding agents
NZ627796A (en) 2012-12-18 2017-07-28 Icahn School Med Mount Sinai Influenza virus vaccines and uses thereof
US9908930B2 (en) 2013-03-14 2018-03-06 Icahn School Of Medicine At Mount Sinai Antibodies against influenza virus hemagglutinin and uses thereof
EP3247389A4 (de) 2015-01-23 2019-10-30 Icahn School of Medicine at Mount Sinai Influenzavirusschutzimpfpläne
EP3374390A1 (de) 2015-11-13 2018-09-19 Visterra, Inc. Zusammensetzungen und verfahren zur behandlung und vorbeugung von grippe
EP3419663A1 (de) 2016-02-24 2019-01-02 Visterra, Inc. Formulierungen von antikörpermolekülen gegen influenzavirus
MX2018015755A (es) 2016-06-15 2019-08-29 Icahn School Med Mount Sinai Proteinas de hemaglutinina de virus de influenza y usos de las mismas.
CA3058652A1 (en) 2017-04-07 2018-10-11 Icahn School Of Medicine At Mount Sinai Anti-influenza b virus neuraminidase antibodies and uses thereof
US12364746B2 (en) 2018-06-21 2025-07-22 Icahn School Of Medicine At Mount Sinai Mosaic influenza virus hemagglutinin polypeptides and uses thereof
CA3132521A1 (en) 2019-03-25 2020-10-01 Visterra, Inc. Compositions and methods for treating and preventing influenza
CA3137160A1 (en) 2019-04-24 2020-10-29 Icahn School Of Medicine At Mount Sinai Anti-influenza b virus neuraminidase antibodies and uses thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0044710A1 (de) * 1980-07-17 1982-01-27 Scripps Clinic And Research Foundation Synthetisches Peptid mit spezifischer Bestimmung der Antigene und Verfahren zur Herstellung von Antigenstoffen daraus

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0044710A1 (de) * 1980-07-17 1982-01-27 Scripps Clinic And Research Foundation Synthetisches Peptid mit spezifischer Bestimmung der Antigene und Verfahren zur Herstellung von Antigenstoffen daraus

Also Published As

Publication number Publication date
IT8348868A0 (it) 1983-08-22
DK203684D0 (da) 1984-04-18
WO1984000687A1 (en) 1984-03-01
AU570929B2 (en) 1988-03-31
PT77230B (en) 1986-02-04
NO161002B (no) 1989-03-13
NO841540L (no) 1984-04-17
IL69556A0 (en) 1983-11-30
FI841583L (fi) 1984-04-19
IT1168636B (it) 1987-05-20
GR78931B (de) 1984-10-02
DK203684A (da) 1984-04-18
KR840006198A (ko) 1984-11-22
AU1947183A (en) 1984-03-07
NO161002C (no) 1989-06-21
ES8505819A1 (es) 1985-06-16
NZ205341A (en) 1988-07-28
IT8348868A1 (it) 1985-02-22
FI841583A7 (fi) 1984-04-19
FI841583A0 (fi) 1984-04-19
ZA836080B (en) 1984-04-25
PT77230A (en) 1983-09-01
JPS59501714A (ja) 1984-10-11
NZ220612A (en) 1988-07-28
IL69556A (en) 1988-05-31
PH18872A (en) 1985-10-21
EP0116629A1 (de) 1984-08-29
ES525088A0 (es) 1985-06-16

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Designated state(s): AT BE CH DE FR GB LI LU NL SE

17P Request for examination filed

Effective date: 19840813

A4 Supplementary search report drawn up and despatched

Effective date: 19870629

17Q First examination report despatched

Effective date: 19890707

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19891118

RIN1 Information on inventor provided before grant (corrected)

Inventor name: ALEXANDER, STEPHEN

Inventor name: GREEN, NICOLA