EP0129785A2 - Conteneur pour médicaments - Google Patents

Conteneur pour médicaments Download PDF

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Publication number
EP0129785A2
EP0129785A2 EP84106800A EP84106800A EP0129785A2 EP 0129785 A2 EP0129785 A2 EP 0129785A2 EP 84106800 A EP84106800 A EP 84106800A EP 84106800 A EP84106800 A EP 84106800A EP 0129785 A2 EP0129785 A2 EP 0129785A2
Authority
EP
European Patent Office
Prior art keywords
film
pulse
container
inputs
dragee
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP84106800A
Other languages
German (de)
English (en)
Other versions
EP0129785A3 (en
EP0129785B1 (fr
Inventor
Udo Simon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
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Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to AT84106800T priority Critical patent/ATE40790T1/de
Publication of EP0129785A2 publication Critical patent/EP0129785A2/fr
Publication of EP0129785A3 publication Critical patent/EP0129785A3/de
Application granted granted Critical
Publication of EP0129785B1 publication Critical patent/EP0129785B1/fr
Expired legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0481—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers working on a schedule basis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035—Blister-type containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0427—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system
    • A61J7/0436—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system resulting from removing a drug from, or opening, a container

Definitions

  • the invention relates to a device for storing and promptly taking medication, namely a medicament container with the features of the preamble of claim 1.
  • Pharmaceuticals often have to be taken at regular intervals. For example, the regular intake of insulin preparations, for example, is often vital for the recipient. Heart preparations also require regular application. Last but not least, contraceptive pills are also considered, which - to ensure effective protection for the recipient - must be taken in a regular daily cycle.
  • a container for pills, tablets or the like which essentially has the shape of a can, the lower part of which can be rotated relative to a cover part provided with a removal opening is arranged.
  • a timer designed as a microprocessor, with a signaling device is built into the container, which is designed to be programmable and is activated as a function of the rotary movements that are necessary to remove pills. With such a device, it is possible to remind the patient or pill recipient to take the medication.
  • a monitoring device which essentially consists of a stationary alarm clock, for example a radio alarm clock, which is intended to control the removal of pills from a foil pack by means of an additional device.
  • the "scanning" of the foil pack takes place electro-optically in that the pill receiving chambers of the foil pack are illuminated by means of a light source and a photosensitive element, so that a registration of the number of pills taken out or an activation of an alarm transmitter connected to the alarm clock is possible.
  • This known device can essentially only be operated in a stationary manner, is complex and expensive and fails particularly when non-transparent film packs are to be scanned.
  • the invention has for its object to provide a portable, compact device for storing and taking medication for a period of time in such a way that regular intake is vigorously promoted and the signal transmitter contained in the device, activated after settable time intervals, is activated immediately with the withdrawal of the drug dose ) the drug container is linked.
  • This object is achieved by the combination of the characterizing features of patent claim 1.
  • the signal transmitter in the case of particularly high-quality pharmaceuticals, it can make sense to design the signal transmitter as an integral part of the pharmaceutical container, the film being able to serve directly as a carrier for the electronic components, for example an integrated circuit. If the device according to the invention is to be used in connection with cheap medicinal products, it is advisable to attach the electronic signal transmitter to the medicament pack by means of a detachable connection, in which case care must then be taken to ensure that electrical contact is made i between the conductor track sections applied to the film and the signal generator in the connection area is taken care of.
  • the device is secured against adjustment by third parties. It is, for example, within the scope of the invention that only the doctor or pharmacist can set the memory to the taking time and the memory content is thus protected against misuse. It is also within the scope of the invention to switch off the inputs electrically after the programming process, which can be done manually or automatically (e.g. 5 minutes after actuation of the first set input).
  • Claim 8 ensures that the impulse line is actually severed when a dragee is pressed through. If the claim speaks of wavy or zigzag, then all embodiments are meant, for example also a U-shaped, meandering, spiral-shaped or the like. Laying of the impulse line over the receiving pocket of the dragee container. Experience has shown that the cover films usually break open in the form of a sickle along the edge of the receiving pockets when pressing through dragees. If the "zigzag arrangement" of the impulse line covers these edge areas, then the desired severing effect will certainly be achieved.
  • the idea of activating any inputs by cutting an impulse line is also transferred to the set inputs.
  • the setting inputs are provided with setting pulse lines that can be cut through manually or by machine and activated, the pharmacist or doctor can, for example, use a pointed pen or the like to carry out the desired initial activation and determine the first taking time and the taking cycles in which the device applies to the patient the next intake reminds.
  • there are two different types of set inputs namely the first for entering a first intake time and the second for entering the cycle time.
  • the programming of the set inputs can also be carried out without errors by laypersons.
  • Either a template is placed over the defined or standardized arrangement of the set inputs, which, for example, bears an imprint in accordance with the time intervals to be programmed (intake cycle, for example, 3 hours) and which has a hole arrangement that comes to lie above the set inputs and only allows the set inputs to be separated, which are to be severed for the corresponding period.
  • the severing itself then has to be carried out by a pointed object which is pushed through the holes.
  • Claim 12 is concerned with the sensing electronics circuit, which recognizes the change in state by tearing the pulse line.
  • the sensing electronics circuit should have two flip-flops connected in series on the input side, the outputs of which are each connected to an exclusive-OR gate.
  • the old output information stored in the upstream flip-flop (input connected to ground through the intact pulse line) is pushed through to the input of the downstream flip-flop, which then in turn represents the old state.
  • the new input information (input "high”, as pulled up with a "pull-up” current source) is read into the upstream flip-flop.
  • the two flip-flops are in different states, to which the downstream exclusive-OR gate reacts, switches through logically and emits a start pulse. If several two-bit shift registers are provided which are to be queried next to one another, the output information of the exclusive-OR gates which are present next to one another must be linked by a simple OR gate.
  • the life of the batteries to be used is reduced to the order of magnitude of the drug lifetimes, so that the device can be used for almost all types of drugs and can be stored together with the batteries used by the pharmaceutical manufacturer, pharmacist and / or doctor without the device suffering damage.
  • Claim 15 makes it possible to check a very large number of receiving pockets with a far smaller number of inputs.
  • the basic principle here is to connect in parallel each impulse line section, which is guided over a tablet, to a resistor applied to the film in a thick-film process.
  • a digital ohm meter in the form of an analog-digital converter must then be present on the input side, which responds to the change in resistance occurring when a pulse line section is cut and emits a start pulse.
  • the resistors in such a resistor chain have different values and the digital ohm meter is able to select resistance jumps of different heights and - depending on the amount of the change in resistance - to control different) stored times as intake interval times, it is possible , with such a pre direction of difficult intake cycles with a plurality of different intake times almost without confusion.
  • Claim 18 provides a further signal source which not only tells the patient that he has to take another pill, but also tells him which of the different types of pills in a packet it is his turn. It could be thought, for example, to design the further signal source as a red light-emitting diode, which clearly indicates to the patient that the red-colored dragees in the package are to be taken. If the additional signal source does not light up, the "other" coated tablets can be taken. Such a device can be particularly useful, for example, if, for example, day and night times require different intake cycles of different tablets. In order not to overwhelm the battery of the device, it can be advantageous to be able to activate the light-emitting diodes - as in a wristwatch - by pressing a button.
  • the device shown in Fig. 1 consists of a drage container 1, on one side edge 2 of which the signal generator 3 is arranged, which is provided as an electrical clock with a signal generator 4 in the form of a "beep loudspeaker" and / or an optical signal generator 21.
  • the detachable connection between the dragee container 1 formed from two adhesively bonded foils and the signal transmitter 3 is designed as a snap-lock connection 5, in which two retaining lips 7, 8 are provided, which are formed in one piece with the housing 6 of the signal transmitter 3, one between them Form receiving slot 9 for the edge 2 and pressurize the two surfaces 10, 11 of the foils 12 under pressure, which ensures a sufficiently firm fit.
  • an impulse line 14 is provided, which is led over the receiving pockets 15 of the dragees 13 and is rit through when the dragees are pushed through the severable film, so that there is a voltage change at the start input 16 connected to the pulse line 14, which activates the electronic timer and reminds the patient of the next dragee after the time preset by the setting device 17.
  • a plurality of further pulse lines 18 are provided with a common pulse line, each of which is guided only via a receiving pocket 15 and is connected to separate further start inputs 19.
  • the electrical connection between the pulse lines 14, 18 and the start inputs 16, 19 can be made via spring contacts which are arranged in the receiving slot 9. Such spring contacts have long been known for contacting printed circuit boards.
  • the signal generator 3 is provided with a digital time display device 20, on which the time remaining until the medication is taken is displayed.
  • FIG. 2 shows an integrated circuit as a signal generator, which is connected on the input side via start inputs 41 to eight start pulse lines 42. These are - Fig. 2 shows un Different embodiments - zigzag, wave-like or the like guided over the receiving pockets 43 and then connected together to a ground line 44.
  • the first setting inputs 45 being provided for entering a first intake time (the patient should take the first pill, for example, in 24 hours), the second setting inputs 46 are for Enter at least one cycle time (the patient should take another pill every 12 hours after taking the first pill).
  • set pulse lines 49, 50 which can be easily cut with a pin due to thinned film areas 51.
  • the set pulse lines are connected to the ground line 44 as long as they are intact. If the connection is missing due to severed areas 47, 48, the corresponding input is activated.
  • An R-C link is also provided as the time base in FIG. 2, but can also be replaced by a watch quartz.
  • a piezo loudspeaker is designated as the signal source at 52, and a battery as the voltage source at 53.
  • the basic circuit diagram shown in FIG. 3 deals with the part of the electronics which is connected downstream of the inputs 41 and is provided for recognizing the change in state of the pulse lines.
  • the pulse lines are designated by dashed lines at 42. Every entrance is with a pull-up current source 55 which, when the input from the ground line 44 is switched off, energizes the D input of a downstream first flip-flop 56 and reads into the flip-flop 56 when a clock occurs on the clock line 57, so that its Output line 58 reflects the new state "pulse line cut through" and passes it on to the first input 59 of an exclusive-OR gate 60.
  • the old status information (pulse line intact) is still present in a second flip-flop 61 connected downstream of the first flip-flop, its output 62 still reflects the old situation, so that the output lines 58 and 62 show different potentials.
  • the output of the exclusive-OR gate 60 switches through and passes the start pulse on to the downstream time base. If - as provided in FIG. 3 - a plurality of start pulse lines 42 are provided, then several two-bit shift registers, each consisting of two flip-flops 56, 61, are necessary, the state of which is to be compared via separate exclusive-OR gates 63 and in one to collect this downstream common OR gate 65.
  • each pulse line section 70 placed over a receiving pocket 43 has a resistor 71 connected in parallel.
  • the start input 41 is followed by an analog-to-digital converter 70 which, when a change in resistance occurs in the upstream start pulse line, emits a start pulse to the downstream time base.
  • a device can be created on the basis of the network shown in FIG indicates different intake cycles of different pharmaceuticals.
  • FIG. 6 shows a perforated template 80 which is laid over the film 12 in the area of the setting inputs 45, 46 and only releases the setting inputs which have to be severed in order to set the printed times.
  • the perforated template and programming stamp can have certain color samples that can be specified by the doctor on the prescription. The pharmacist is then able to program the medication container correctly based solely on the color of the perforated template or the stamp.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
EP19840106800 1983-06-25 1984-06-14 Conteneur pour médicaments Expired EP0129785B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT84106800T ATE40790T1 (de) 1983-06-25 1984-06-14 Arzneimittelbehaelter.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3322920 1983-06-25
DE3322920 1983-06-25

Publications (3)

Publication Number Publication Date
EP0129785A2 true EP0129785A2 (fr) 1985-01-02
EP0129785A3 EP0129785A3 (en) 1986-03-05
EP0129785B1 EP0129785B1 (fr) 1989-02-15

Family

ID=6202379

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19840106800 Expired EP0129785B1 (fr) 1983-06-25 1984-06-14 Conteneur pour médicaments

Country Status (4)

Country Link
EP (1) EP0129785B1 (fr)
AT (1) ATE40790T1 (fr)
DE (1) DE3476732D1 (fr)
HK (1) HK10890A (fr)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2581214A1 (fr) * 1985-04-25 1986-10-31 Jean Mouzard Module temporise pour rappel de vaccins ou autres
EP0191168B1 (fr) * 1985-02-09 1990-03-14 Udo Simon Dispositif pour le stockage de médicaments et leur absorption provoquée en fonction du temps
EP0526166A3 (fr) * 1991-07-29 1994-02-09 Dessertine Albert L
WO1996004881A1 (fr) * 1994-08-08 1996-02-22 Rudolf Loidl Dispositif de distribution de medicaments au moment ou on doit les prendre
FR2745922A1 (fr) * 1996-03-05 1997-09-12 Jager Ivan Dispositif pour rememorer une operation relative a un objet determine et application de ce dispositif
EP0796605A1 (fr) * 1996-03-21 1997-09-24 Alusuisse Technology & Management AG Feuille de fermeture avec pistes conductrices
EP0796606A1 (fr) * 1996-03-21 1997-09-24 Alusuisse Technology & Management AG Feuille de fermeture avec pistes conductrices
US5836474A (en) * 1993-11-26 1998-11-17 Novatelligence Ab Storage means specially intended for medicaments
EP0972507A1 (fr) 1998-05-29 2000-01-19 Alusuisse Technology & Management AG Feuille de fermeture avec pistes conductrices
DE4313557C2 (de) * 1993-04-26 2001-11-15 Dietrich Jansen Elektronischer Notizkalender für Entsorgungstermine
EP2826456A1 (fr) * 2013-06-28 2015-01-21 Commissariat à l'Énergie Atomique et aux Énergies Alternatives Membrane et système de contrôle d'une ouverture de la membrane

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7828147B2 (en) 2004-04-24 2010-11-09 Inrange Systems, Inc. Multi-layer medication carrier
CN101103350A (zh) 2004-04-24 2008-01-09 鹰锐系统股份有限公司 内置非顺序性远端药物管理和遵从系统

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2603248B1 (de) * 1976-01-29 1977-06-30 Dieter Homeier Überwachungseinrichtung
US4223801A (en) * 1978-01-26 1980-09-23 Carlson Torsten S Automatic periodic drug dispensing system
US4258354A (en) * 1979-05-11 1981-03-24 Amiram Carmon Portable alarm device
DE2921520A1 (de) * 1979-05-28 1980-12-04 Helmut Pelzer Ueberwachungsvorrichtung
US4382688A (en) * 1981-01-26 1983-05-10 Machamer Roy J Timed medication dispenser
JPS57150963A (en) * 1981-02-12 1982-09-17 Robaato Jiyankeru Design Ltd Improved pill

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0191168B1 (fr) * 1985-02-09 1990-03-14 Udo Simon Dispositif pour le stockage de médicaments et leur absorption provoquée en fonction du temps
FR2581214A1 (fr) * 1985-04-25 1986-10-31 Jean Mouzard Module temporise pour rappel de vaccins ou autres
EP0526166A3 (fr) * 1991-07-29 1994-02-09 Dessertine Albert L
DE4313557C2 (de) * 1993-04-26 2001-11-15 Dietrich Jansen Elektronischer Notizkalender für Entsorgungstermine
US5836474A (en) * 1993-11-26 1998-11-17 Novatelligence Ab Storage means specially intended for medicaments
WO1996004881A1 (fr) * 1994-08-08 1996-02-22 Rudolf Loidl Dispositif de distribution de medicaments au moment ou on doit les prendre
AT401725B (de) * 1994-08-08 1996-11-25 Loidl Rudolf Vorrichtung zum zeitpunktgerechten einnehmen von medikamenten
FR2745922A1 (fr) * 1996-03-05 1997-09-12 Jager Ivan Dispositif pour rememorer une operation relative a un objet determine et application de ce dispositif
EP0796605A1 (fr) * 1996-03-21 1997-09-24 Alusuisse Technology & Management AG Feuille de fermeture avec pistes conductrices
US5871831A (en) * 1996-03-21 1999-02-16 Alusuisse Technology & Management Ltd. Lidding foil with conductive strips
EP0796606A1 (fr) * 1996-03-21 1997-09-24 Alusuisse Technology & Management AG Feuille de fermeture avec pistes conductrices
EP0972507A1 (fr) 1998-05-29 2000-01-19 Alusuisse Technology & Management AG Feuille de fermeture avec pistes conductrices
EP2826456A1 (fr) * 2013-06-28 2015-01-21 Commissariat à l'Énergie Atomique et aux Énergies Alternatives Membrane et système de contrôle d'une ouverture de la membrane

Also Published As

Publication number Publication date
DE3476732D1 (en) 1989-03-23
EP0129785A3 (en) 1986-03-05
EP0129785B1 (fr) 1989-02-15
ATE40790T1 (de) 1989-03-15
HK10890A (en) 1990-02-16

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