EP0198014A4 - Ein gen für ein protein mit erythroid erhöhender wirkung enthaltende vektoren und rekombinante dns-verfahren zu deren herstellung. - Google Patents

Ein gen für ein protein mit erythroid erhöhender wirkung enthaltende vektoren und rekombinante dns-verfahren zu deren herstellung.

Info

Publication number
EP0198014A4
EP0198014A4 EP19850905157 EP85905157A EP0198014A4 EP 0198014 A4 EP0198014 A4 EP 0198014A4 EP 19850905157 EP19850905157 EP 19850905157 EP 85905157 A EP85905157 A EP 85905157A EP 0198014 A4 EP0198014 A4 EP 0198014A4
Authority
EP
European Patent Office
Prior art keywords
protein
erythroid
gene
producing
recombinant dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19850905157
Other languages
English (en)
French (fr)
Other versions
EP0198014A1 (de
Inventor
Eugene Brown
Steven C Clark
David W Golde
Judith C Casson
Rodney Hewick
Carol A Westbrook
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
University of California Berkeley
University of California San Diego UCSD
Original Assignee
Sandoz AG
University of California Berkeley
University of California San Diego UCSD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG, University of California Berkeley, University of California San Diego UCSD filed Critical Sandoz AG
Publication of EP0198014A1 publication Critical patent/EP0198014A1/de
Publication of EP0198014A4 publication Critical patent/EP0198014A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP19850905157 1984-10-01 1985-10-01 Ein gen für ein protein mit erythroid erhöhender wirkung enthaltende vektoren und rekombinante dns-verfahren zu deren herstellung. Withdrawn EP0198014A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65659084A 1984-10-01 1984-10-01
US656590 1984-10-01

Publications (2)

Publication Number Publication Date
EP0198014A1 EP0198014A1 (de) 1986-10-22
EP0198014A4 true EP0198014A4 (de) 1987-11-23

Family

ID=24633705

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19850905157 Withdrawn EP0198014A4 (de) 1984-10-01 1985-10-01 Ein gen für ein protein mit erythroid erhöhender wirkung enthaltende vektoren und rekombinante dns-verfahren zu deren herstellung.

Country Status (3)

Country Link
EP (1) EP0198014A4 (de)
JP (1) JPS62500424A (de)
WO (1) WO1986002100A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0188312A3 (de) * 1985-01-07 1988-01-13 Celltech Limited Verfahren zur Herstellung eines Proteins
KR940010862B1 (ko) * 1985-02-05 1994-11-18 씨네겐 바이오로지칼즈, 인코포레이티드 유용한 메탈로프로테이나제 억제제 씨퀀스 재조합 벡터계의 제조를 위한 dna 재조합 방법
US7247704B2 (en) 2000-12-18 2007-07-24 Arriva Pharmaceuticals, Inc. Multifunctional protease inhibitors and their use in treatment of disease

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0188312A2 (de) * 1985-01-07 1986-07-23 Celltech Limited Verfahren zur Herstellung eines Proteins
EP0189784A1 (de) * 1985-01-18 1986-08-06 G.D. Searle & Co. Menschlicher, natürlicher Collagenaseninhibitor
WO1986004608A1 (en) * 1985-02-05 1986-08-14 Synergen Biologicals, Inc. Metalloproteinase inhibitor sequence recombinant vector system for using same and recombinant-dna method for the manufacture of same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4438032A (en) * 1981-01-30 1984-03-20 The Regents Of The University Of California Unique T-lymphocyte line and products derived therefrom

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0188312A2 (de) * 1985-01-07 1986-07-23 Celltech Limited Verfahren zur Herstellung eines Proteins
EP0189784A1 (de) * 1985-01-18 1986-08-06 G.D. Searle & Co. Menschlicher, natürlicher Collagenaseninhibitor
WO1986004608A1 (en) * 1985-02-05 1986-08-14 Synergen Biologicals, Inc. Metalloproteinase inhibitor sequence recombinant vector system for using same and recombinant-dna method for the manufacture of same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO8602100A1 *

Also Published As

Publication number Publication date
WO1986002100A1 (en) 1986-04-10
EP0198014A1 (de) 1986-10-22
JPS62500424A (ja) 1987-02-26

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19860531

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE FR GB IT LI LU NL SE

A4 Supplementary search report drawn up and despatched

Effective date: 19871123

17Q First examination report despatched

Effective date: 19900706

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19910117

RIN1 Information on inventor provided before grant (corrected)

Inventor name: CASSON, JUDITH, C.

Inventor name: WESTBROOK, CAROL, A.

Inventor name: GOLDE, DAVID, W.

Inventor name: CLARK, STEVEN, C.

Inventor name: BROWN, EUGENE

Inventor name: HEWICK, RODNEY