JPS62500424A - 赤血球の増強活性を有する蛋白質のための遺伝子を含有するベクタ−および前記蛋白質を生産するための組み換えｄｎａ法 - Google Patents

赤血球の増強活性を有する蛋白質のための遺伝子を含有するベクタ−および前記蛋白質を生産するための組み換えｄｎａ法

Info

Publication number
JPS62500424A
JPS62500424A JP60504559A JP50455985A JPS62500424A JP S62500424 A JPS62500424 A JP S62500424A JP 60504559 A JP60504559 A JP 60504559A JP 50455985 A JP50455985 A JP 50455985A JP S62500424 A JPS62500424 A JP S62500424A
Authority
JP
Japan
Prior art keywords
epa
protein
cells
gene
dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP60504559A
Other languages
English (en)
Japanese (ja)
Inventor
ブラウン，ユージン
クラーク，スチーブン・シー
ゴールド，デビツド・ダブリユー
カツソン，ジユデイス・シー
ヒユーイツク，ロドニイ
ウエストブルツク，キヤロル・エイ
Original Assignee
サンド・リミテッド
ザ・リージエンツ・オブ・ザ・ユニバーシテイ・オブ・カリフオルニア
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by サンド・リミテッド, ザ・リージエンツ・オブ・ザ・ユニバーシテイ・オブ・カリフオルニア filed Critical サンド・リミテッド
Publication of JPS62500424A publication Critical patent/JPS62500424A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP60504559A 1984-10-01 1985-10-01 赤血球の増強活性を有する蛋白質のための遺伝子を含有するベクタ−および前記蛋白質を生産するための組み換えｄｎａ法 Pending JPS62500424A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65659084A 1984-10-01 1984-10-01
US656590 1984-10-01

Publications (1)

Publication Number Publication Date
JPS62500424A true JPS62500424A (ja) 1987-02-26

Family

ID=24633705

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60504559A Pending JPS62500424A (ja) 1984-10-01 1985-10-01 赤血球の増強活性を有する蛋白質のための遺伝子を含有するベクタ−および前記蛋白質を生産するための組み換えｄｎａ法

Country Status (3)

Country Link
EP (1) EP0198014A4 (de)
JP (1) JPS62500424A (de)
WO (1) WO1986002100A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK4286A (da) * 1985-01-07 1986-07-08 Celltech Ltd Fremgangsmaade til fremstilling af en metalloproteinaseinhibitor
ATE89005T1 (de) * 1985-02-05 1993-05-15 Synergen Biolog Inc Rekombinantes vektorsystem fuer metalloproteinase- inhibitorsequenz und dessen verwendung und herstellung nach dem rekombinant-dns-verfahren.
US7247704B2 (en) 2000-12-18 2007-07-24 Arriva Pharmaceuticals, Inc. Multifunctional protease inhibitors and their use in treatment of disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4438032A (en) * 1981-01-30 1984-03-20 The Regents Of The University Of California Unique T-lymphocyte line and products derived therefrom
DK4286A (da) * 1985-01-07 1986-07-08 Celltech Ltd Fremgangsmaade til fremstilling af en metalloproteinaseinhibitor
EP0189784B1 (de) * 1985-01-18 1989-11-08 G.D. Searle & Co. Menschlicher, natürlicher Collagenaseninhibitor
ATE89005T1 (de) * 1985-02-05 1993-05-15 Synergen Biolog Inc Rekombinantes vektorsystem fuer metalloproteinase- inhibitorsequenz und dessen verwendung und herstellung nach dem rekombinant-dns-verfahren.

Also Published As

Publication number Publication date
EP0198014A4 (de) 1987-11-23
WO1986002100A1 (en) 1986-04-10
EP0198014A1 (de) 1986-10-22

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