EP0217862A4 - In-vitro-syntheseverfahren von l-tryptophan. - Google Patents

In-vitro-syntheseverfahren von l-tryptophan.

Info

Publication number
EP0217862A4
EP0217862A4 EP19860902176 EP86902176A EP0217862A4 EP 0217862 A4 EP0217862 A4 EP 0217862A4 EP 19860902176 EP19860902176 EP 19860902176 EP 86902176 A EP86902176 A EP 86902176A EP 0217862 A4 EP0217862 A4 EP 0217862A4
Authority
EP
European Patent Office
Prior art keywords
tryptophan
vitro
synthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19860902176
Other languages
English (en)
French (fr)
Other versions
EP0217862A1 (de
Inventor
Humg-Yu Hsiao
Tena T Wei
David M Anderson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genex Corp
Original Assignee
Genex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genex Corp filed Critical Genex Corp
Publication of EP0217862A1 publication Critical patent/EP0217862A1/de
Publication of EP0217862A4 publication Critical patent/EP0217862A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/227—Tryptophan

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP19860902176 1985-03-18 1986-03-17 In-vitro-syntheseverfahren von l-tryptophan. Withdrawn EP0217862A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71261285A 1985-03-18 1985-03-18
US712612 1985-03-18

Publications (2)

Publication Number Publication Date
EP0217862A1 EP0217862A1 (de) 1987-04-15
EP0217862A4 true EP0217862A4 (de) 1989-12-28

Family

ID=24862855

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19860902176 Withdrawn EP0217862A4 (de) 1985-03-18 1986-03-17 In-vitro-syntheseverfahren von l-tryptophan.

Country Status (3)

Country Link
EP (1) EP0217862A4 (de)
JP (1) JPS62502934A (de)
WO (1) WO1986005515A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3882394T2 (de) * 1987-03-03 1993-12-16 Light Oil Utilization Res Ass Plasmide.
GB8819135D0 (en) * 1988-08-11 1988-09-14 Celltech Ltd Tryptophan production
WO2007095682A1 (en) * 2006-02-24 2007-08-30 The Australian Wine Research Institute Methods and micro-organisms for modulating the conversion of non-volatile sulfur compounds to volatile thiol compounds
CN111961656B (zh) * 2020-09-03 2022-07-22 中国科学院上海高等研究院 一种丝氨酸羟甲基转移酶的突变体及其用途
CN115261365B (zh) * 2022-06-22 2024-01-30 南通紫琅生物医药科技有限公司 色氨酸合成酶突变体及其应用
CN120683027A (zh) * 2025-04-29 2025-09-23 上海锐康生物技术研发有限公司 一种高产l-色氨酸的重组微生物及其构建方法和应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2263302A1 (de) * 1974-03-05 1975-10-03 Bofors Ab
GB2048266A (en) * 1979-05-09 1980-12-10 Mitsui Toatsu Chemicals Enzymatic preparation of l-tryptophan
GB2130216A (en) * 1982-11-19 1984-05-31 Genex Corp Enzymatic synthesis of L-serine

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2263302A1 (de) * 1974-03-05 1975-10-03 Bofors Ab
GB2048266A (en) * 1979-05-09 1980-12-10 Mitsui Toatsu Chemicals Enzymatic preparation of l-tryptophan
GB2130216A (en) * 1982-11-19 1984-05-31 Genex Corp Enzymatic synthesis of L-serine

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BIOTECHNOLOGY & BIOENGINEERING, vol. 26, no. 4, April 1984, pages 308-314, John Wiley & Sons, Inc., New York, US; U. BEHRENDT et al.: "The production of L-serine with a methylotrophic microorganism using the L-serine pathway and coupling with an L-tryptophan-producing process" *
JOURNAL OF GENERAL MICROBIOLOGY, vol. 130, 1984, pages 3091-3100, SGM, GB; G.S. SKOGMAN et al.: "Factors affecting the biosynthesis of L-tryptophan by genetically modified strains of Escherichia coli" *
See also references of WO8605515A1 *

Also Published As

Publication number Publication date
EP0217862A1 (de) 1987-04-15
WO1986005515A1 (en) 1986-09-25
JPS62502934A (ja) 1987-11-26

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE FR GB IT LI LU NL SE

17P Request for examination filed

Effective date: 19870325

A4 Supplementary search report drawn up and despatched

Effective date: 19891228

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19901003

RIN1 Information on inventor provided before grant (corrected)

Inventor name: HSIAO, HUMG-YU

Inventor name: WEI, TENA, T.

Inventor name: ANDERSON, DAVID, M.