EP0258637A1 - Pulvérisateur de poche à ultrasons - Google Patents

Pulvérisateur de poche à ultrasons Download PDF

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Publication number
EP0258637A1
EP0258637A1 EP87111004A EP87111004A EP0258637A1 EP 0258637 A1 EP0258637 A1 EP 0258637A1 EP 87111004 A EP87111004 A EP 87111004A EP 87111004 A EP87111004 A EP 87111004A EP 0258637 A1 EP0258637 A1 EP 0258637A1
Authority
EP
European Patent Office
Prior art keywords
ultrasonic
pocket atomizer
ultrasonic pocket
housing part
atomizer according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP87111004A
Other languages
German (de)
English (en)
Other versions
EP0258637B1 (fr
Inventor
Wolf-Dietrich Dr. Drews
Martin Dipl.-Ing.(FH) Rüttel
Klaus Van Der Linden
Jürgen Friedrich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens AG
Siemens Corp
Original Assignee
Siemens AG
Siemens Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siemens AG, Siemens Corp filed Critical Siemens AG
Priority to AT87111004T priority Critical patent/ATE54071T1/de
Publication of EP0258637A1 publication Critical patent/EP0258637A1/fr
Application granted granted Critical
Publication of EP0258637B1 publication Critical patent/EP0258637B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
    • B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
    • B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
    • B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
    • B05B17/0623—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers coupled with a vibrating horn

Definitions

  • the invention relates to an ultrasonic pocket atomizer according to the preamble of patent claim 1.
  • Ultrasonic devices are also known for atomizing liquids. From DE-PS 20 32 433 devices with a piezoelectric vibration system are known, with which large vibration amplitudes can be achieved with comparatively little electrical energy. With such atomizing devices, it should be possible to produce very fine droplets with a relatively homogeneous distribution of the droplet size be.
  • the use of such piezoelectric vibration systems when using an electronic circuit and design as a hand-held device has become known from DE-PS 22 39 950.
  • the currently known ultrasound devices do not yet meet the requirements in terms of dimensions, weight, energy requirements and droplet size range, as well as exact drug dosages.
  • the metered dose aerosols currently used work with propellant gas, which is not desirable.
  • Inhalers are also known in which capsules filled with pharmaceutical powder are used and the powder of which is expelled via an air transport stream.
  • these inhalers cannot be filled with several single doses.
  • Another disadvantage of the metered dose aerosols working with propellant gas is that the high drug particle speed means that a certain proportion does not get into the lungs but, for example, into the esophagus.
  • the mechanical hand-held nebulizers have the particular disadvantage that a high expenditure of force is required to actuate the pump ball and the addition of preservatives to the medicament.
  • the object of the invention is to provide a device for the inhalation of active ingredients which enables the production of a suspended aerosol in which at least 50% of the droplets of the aerosol produced have a diameter of 20 microns and the majority of the droplets have a diameter in the range of 1 to 5 ⁇ m. It must also be possible to use the active ingredients in the trancheobronchial tree.
  • the application of the agent to be atomized must be possible without propellant gas and with precise dosing. A cold stimulus must not occur during application.
  • the aerosol should be suspended and if possible not have its own speed.
  • An ultrasonic pocket atomizer according to the invention enables low-noise application of substances without cold stimulus and without the use of a propellant gas.
  • the dosing of the substance to be atomized can be carried out with an accuracy of over 95% before atomization, which is very important in particular in the case of pharmaceuticals.
  • a suspended aerosol is generated in which at least 50% of the droplets of the aerosol produced have a diameter ⁇ 20 ⁇ m and the active ingredients can be used in the trancheobronchial tree.
  • the device according to the invention which can be operated in any position, is light, very handy and easy to accommodate and carry in the handbag or clothing.
  • the filling with the agent to be atomized takes place through easy replacement of cartridges.
  • the battery pack integrated in the lower part of the device is removable and rechargeable. Battery operation is possible and easy.
  • FIG. 2 being a longitudinal section of FIG. 1.
  • An ultrasonic pocket atomizer according to the invention consists of a piezoelectric vibration system 1 with an operating frequency in the range from 1 to 5 MHz, which is installed in the lower housing part 13 of the plastic housing in a liquid-tight manner.
  • Suitable plastics for this are, for example, acrylonitrile-butadiene-styrene copolymers (ABS).
  • ABS acrylonitrile-butadiene-styrene copolymers
  • the tightness is achieved by pouring the vibration system 1 into the holder 2 or by sealing with O-rings 28.
  • a particularly suitable casting compound is silicone rubber.
  • the vibrating system 1 is excited by an electronic circuit 3 to produce ultrasonic vibrations in the MHz range and atomizes the medicament 5 applied to the vibrating system 1 through the cartridge 4.
  • the electronic circuit is supplied with electrical energy via the rechargeable battery pack 6.
  • the device can be recharged with the integrated rechargeable battery by additionally routing the contacts 7 outwards in parallel.
  • the battery pack is removable, replaceable and rechargeable even without the device by means of a sliding device 8.
  • the dosing cartridge 4 filled with drug liquid is movably mounted in the upper housing part 9.
  • the button 10 moves Cartridge to the transducer.
  • a magnet 11 attached to the cartridge closes a switch 12 attached to the lower part 13 of the device.
  • the magnetic switch 11, 12 makes it possible to seal the lower housing part 13 in a liquid-tight manner with respect to the upper housing part 9.
  • the electronics are activated and the ultrasound atomizer is supplied with energy after an electronically specified period of time.
  • the time span is dimensioned such that there is sufficient time between actuation of the magnetic switch and the start of atomization.
  • the cartridge After closing the magnetic switch, the cartridge is moved forward, i.e. in the direction of the oscillation system, finally moves and strikes the thickened part of the body against a wall 14. Since the mechanical resistance of the plastic spring 15 is lower than the spring 21 integrated in the cartridge, the pressure on the cartridge by the operator continues to exert pressure on it only now slightly compressed and a precisely dosed amount of drug 5 is dispensed. By relieving the pressure on the cartridge, it moves back to its starting position. The quantity of medicament dispensed at the tip of the cartridge is stripped off on the atomizing plate 24 when it returns to the starting position and atomized after stripping.
  • the aerosol can be stored in the intake manifold 17 and is inhaled by the user.
  • the openings in the wall 18 are dimensioned such that sufficient air can be added to the intake manifold during the inhalation process.
  • the mouth of the user can enclose the intake manifold well.
  • the connector can be flush with one edge of the housing and the device dimensions can be kept small.
  • a cover 20 is provided for closing the intake manifold and is captively attached to the upper part of the device via a plastic film hinge 22.
  • the upper housing part 9 Since the upper housing part 9 is easily removable and inexpensive to produce, it can be discarded after the cartridge 4 filled with medication has been emptied. It is a very hygienic solution.
  • a transparent window 23 made of plastic is integrated on the upper part, which shows the amount of liquid still present. It allows you to monitor the level of the drug in the cartridge.
  • an electrical signal 25 indicates the state of charge of the rechargeable battery.
  • Suitable is e.g. a light emitting diode.
  • the outer contours of the device 26 are rounded, so that the user is inevitably given a corresponding location at which the device can be parked.
  • This storage container can be designed, for example, in such a way that the battery is simultaneously recharged during storage.
  • the integrated contacts are arranged asymmetrically with respect to the underside of the device, a specific position can even be specified in the storage container.
  • the upper housing part 9 is easily detachably connected to the lower housing part 13 by a snap-lock connection 16.
  • the device can also be designed so that, for example, the magnetic switch 11, 12 only triggers when the thickened part of the cartridge hits the wall.
  • Devices according to the invention are used with particular advantage for medical applications, in particular for asthmatics.
  • An application as a room and body spray device is also possible, as well as a humidifier.

Landscapes

  • Special Spraying Apparatus (AREA)
EP87111004A 1986-08-11 1987-07-29 Pulvérisateur de poche à ultrasons Expired - Lifetime EP0258637B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT87111004T ATE54071T1 (de) 1986-08-11 1987-07-29 Ultraschall-taschenzerstaeubergeraet.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19863627222 DE3627222A1 (de) 1986-08-11 1986-08-11 Ultraschall-taschenzerstaeubergeraet
DE3627222 1986-08-11

Publications (2)

Publication Number Publication Date
EP0258637A1 true EP0258637A1 (fr) 1988-03-09
EP0258637B1 EP0258637B1 (fr) 1990-06-27

Family

ID=6307169

Family Applications (1)

Application Number Title Priority Date Filing Date
EP87111004A Expired - Lifetime EP0258637B1 (fr) 1986-08-11 1987-07-29 Pulvérisateur de poche à ultrasons

Country Status (7)

Country Link
US (1) US4877989A (fr)
EP (1) EP0258637B1 (fr)
JP (1) JP2540462B2 (fr)
AT (1) ATE54071T1 (fr)
CA (1) CA1313098C (fr)
DE (2) DE3627222A1 (fr)
ES (1) ES2015558B3 (fr)

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EP0373237A1 (fr) * 1988-12-13 1990-06-20 Siemens Aktiengesellschaft Dispositif d'inhalateur de poche
EP0373419A3 (fr) * 1988-12-12 1991-07-10 Siemens Aktiengesellschaft Changeur de batterie pour appareil médical
FR2705911A1 (fr) * 1993-06-02 1994-12-09 Oreal Appareil de nébulisation piézoélectrique.
DE4431019A1 (de) * 1994-08-31 1996-03-07 Siemens Ag Zerstäuberkopf
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US5950619A (en) * 1995-03-14 1999-09-14 Siemens Aktiengesellschaft Ultrasonic atomizer device with removable precision dosating unit
US5970974A (en) * 1995-03-14 1999-10-26 Siemens Aktiengesellschaft Dosating unit for an ultrasonic atomizer device
WO2007120565A1 (fr) * 2006-04-11 2007-10-25 S.C. Johnson & Son, Inc. Dispositif aérosol électronique
EP1389064B1 (fr) * 2001-01-26 2010-08-04 Yoni Iger Appareil permettant la delivrance de substances a des composants biologiques
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US12213516B2 (en) 2019-12-15 2025-02-04 Shaheen Innovations Holding Limited Ultrasonic mist inhaler
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US12538944B2 (en) 2019-12-15 2026-02-03 Shaheen Innovations Holding Limited Nicotine delivery device with identification arrangement

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Also Published As

Publication number Publication date
DE3763372D1 (de) 1990-08-02
EP0258637B1 (fr) 1990-06-27
CA1313098C (fr) 1993-01-26
JP2540462B2 (ja) 1996-10-02
DE3627222A1 (de) 1988-02-18
US4877989A (en) 1989-10-31
ES2015558B3 (en) 1990-09-01
ATE54071T1 (de) 1990-07-15
JPS6349271A (ja) 1988-03-02

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