EP0295204A1 - Mehrkammerbehälter zur Aufbewahrung und nachfolgenden Mischung aktiver Komponenten - Google Patents

Mehrkammerbehälter zur Aufbewahrung und nachfolgenden Mischung aktiver Komponenten Download PDF

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Publication number
EP0295204A1
EP0295204A1 EP19880810325 EP88810325A EP0295204A1 EP 0295204 A1 EP0295204 A1 EP 0295204A1 EP 19880810325 EP19880810325 EP 19880810325 EP 88810325 A EP88810325 A EP 88810325A EP 0295204 A1 EP0295204 A1 EP 0295204A1
Authority
EP
European Patent Office
Prior art keywords
passage
envelope
closable
container according
compartment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP19880810325
Other languages
English (en)
French (fr)
Other versions
EP0295204B1 (de
Inventor
Maurice Loretti
Pierre Vanat
Jacques Andre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vifor Medical AG
Original Assignee
Vifor SA
Vifor Medical AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4225101&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP0295204(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vifor SA, Vifor Medical AG filed Critical Vifor SA
Priority to AT88810325T priority Critical patent/ATE65473T1/de
Publication of EP0295204A1 publication Critical patent/EP0295204A1/de
Application granted granted Critical
Publication of EP0295204B1 publication Critical patent/EP0295204B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2093—Containers having several compartments for products to be mixed
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • B65D81/3261—Flexible containers having several compartments
    • B65D81/3266—Flexible containers having several compartments separated by a common rupturable seal, a clip or other removable fastening device
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10—Bag-type containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/202—Separating means
    • A61J1/2027—Separating means having frangible parts

Definitions

  • the subject of the invention is a container intended for the separate storage of active compounds, in particular in the form of liquids or solutions, and for their subsequent mixing just before use.
  • This invention finds its application in very varied fields such as medicine, chemistry or cosmetics for example.
  • a known model of container with two compartments can be succinctly described as follows: the upper compartment, intended to contain an aqueous solution of amino acids, is provided at its top with a closable passage serving to introduce said solution and, at its base , a closed transfer passage opening into the lower compartment, intended to contain the glucose solution. After rupture of the obturation, the sterile mixture of amino acids is transferred to the lower compartment, the final product then being able to flow through an evacuation passage, located at the base of the lower compartment.
  • Such containers are based on flexible polymerized material, polyethylene for example.
  • Such containers are not suitable, however, for the sterile storage and administration of more complex mixtures, such as ternary mixtures of active compounds.
  • polymeric materials having all the desired qualities, in particular chemical inertness with respect to amino acids, glucose and their mixture, the skilled person is totally helpless when it comes to to solve this problem for more complex mixtures. This is inter alia the case when one endeavors to sterilize and store separately amino acids, lipids and sugars such as glucose, then to administer the resulting mixture in the form of a solution for infusion.
  • the invention makes it possible to advantageously fill this gap and to offer a solution which is not only limited to the pharmaceutical field, which advantageously applies to all kinds of fields. It consists of a container as defined in claim 1.
  • the container 1 intended for the separate storage of active compounds, in particular liquids or solutions, and for their subsequent mixing just before use, comprises a flexible waterproof envelope divided into several compartments each provided with a closable passage allowing to introduce therein from the outside a compound or a mixture of compounds, respectively to evacuate its content towards the outside, and each provided with a closed passage which can be released at will to allow the content of a compartment given in another.
  • This container 1 is characterized by the fact that it comprises at least three compartments 3, 4, 5 separated from each other by leaktight welds 6 of the material of the envelope 2 and that the envelope 2 consists of a homogeneous flexible polymerized material, chemically inert with respect to each of the compounds considered and their mixtures.
  • the container 1 comprises, in its upper part two adjacent compartments 3, 4 each provided at their top with a closable introduction passage 7, 8 and at their base with a closed transfer passage 10, 11 opening into the lower compartment 5, the latter being provided at its base with a closable evacuation passage 9.
  • FIG. 1 Such an execution is illustrated in FIG. 1.
  • the container 1 has in its upper part two adjacent compartments 3, 4 each provided at their top with a closable insertion passage 7 ′, 8 ′, the compartment 3 comprising at its base a closed transfer passage 10 ′ opening into the adjacent compartment 4, the latter being provided at its base with a closed transfer passage 11 ′ opening into the lower compartment 5 itself provided with a closable evacuation passage 9 ′.
  • a closed transfer passage 10 ′ opening into the adjacent compartment 4
  • the latter being provided at its base with a closed transfer passage 11 ′ opening into the lower compartment 5 itself provided with a closable evacuation passage 9 ′.
  • the introduction passages 7, 8 respectively 7 ′, 8 ′ are most generally rigid or semi-rigid and welded to the material of the envelope. They are most often closed after the introduction of the given compounds into their respective compartments, using any suitable means ensuring an absolutely sealed closure, preferably resistant to the conditions of sterilization.
  • the transfer passages 10, 11 respectively 10 ′, 11 ′ may include rigid or semi-rigid parts depending on the circumstances. They can consist of a manually breakable tip, a tearable weld under the effect of lateral pressure or a ball tightened in a flexible tube and which can be expelled manually. Such passages use known techniques and can ensure, if necessary, the sterile transfer of the contents from one compartment to another. As a rule, they are welded to the material of the envelope.
  • the material of the envelope must meet several conditions. Essentially, it must be flexible, of homogeneous composition and chemically and biologically inert with respect to each of the compounds considered and their mixtures. It must also be weldable using the usual techniques such as hot welding, ultrasonic or high frequency and compatible with the common materials used to make the passages mentioned above. It must also be impermeable to liquids, gases and vapors and preferably transparent, although the latter condition is not essential.
  • the envelope 2 may consist of a single sheet of a polymerized material meeting the conditions listed above.
  • the envelope 2 can also consist of a composite sheet, double or even triple as the case may be, only the material in contact with the given compounds then having to be chemically inert with respect to these or their mixtures.
  • polystyrene-ethylene-butyl examples include polyethylene, polypropylene, blocked polyether polyamide or mixtures of polyethylene and styrene-ethylene-butyl, polyethylene and ethylene-vinyl acetate, linear polyethylene, polypropylene and styrene-ethylene-butyl.
  • a single sheet or, as the case may be, the inner layer of a composite sheet is preferably formed.
  • complex materials constituting composite sheets the following may be mentioned: polyamide-polypropylene (PA / PP), linear polyamide-polyethylene, low density or high density (PA / PE) for example.
  • Such materials have been found to be particularly well suited to the manufacture of containers according to the invention, in particular leaktight flexible sachets intended for separate storage and then for the subsequent mixing, under sterile conditions, of lipids, amino acids and solutions of sugars such as glucose.
  • the container of the invention can be used as follows.
  • compartment 3 of the container according to FIG. 1 an emulsion based on lipids (essentially triglycerides) assimilated by the human body is introduced.
  • compartment 4 an aqueous solution of essential amino acids is introduced and, in the lower container 5, an aqueous solution of glucose, for example at 40% in H2O.
  • the introduction of these liquids is carried out according to the usual techniques, through the passages 7, 8 and 9 respectively, which are then closed in a sealed manner, after introduction.
  • the container thus filled can then be sterilized in an autoclave (temperature> 100 ° C) and stored as it is for several months, even several years.
  • the procedure is as follows: the breakable passage 11 is manually broken and the amino acid solution is passed into the lower compartment 5.
  • the mixture can be activated by trituration of compartment 5.
  • the procedure is identical with the breakable passage 10, passing the lipid emulsion into compartment 5.
  • the resulting mixture ready for use, can be administered after the tip 9 has been connected to an infusion probe, for example.
  • Such a container can also be used in cosmetics (treating emulsions, coloring shampoos), in the field of adhesives with several components, synthetic resins or for the preparation of reactive mixtures of all kinds.

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Package Specialized In Special Use (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Packages (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
EP19880810325 1987-05-29 1988-05-24 Mehrkammerbehälter zur Aufbewahrung und nachfolgenden Mischung aktiver Komponenten Expired - Lifetime EP0295204B1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT88810325T ATE65473T1 (de) 1987-05-29 1988-05-24 Mehrkammerbehaelter zur aufbewahrung und nachfolgenden mischung aktiver komponenten.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH02066/87A CH686778A5 (fr) 1987-05-29 1987-05-29 Récipient destiné au stockage séparé de composés actifs et à leur mélange subséquent.
CH2066/87 1987-05-29

Publications (2)

Publication Number Publication Date
EP0295204A1 true EP0295204A1 (de) 1988-12-14
EP0295204B1 EP0295204B1 (de) 1991-07-24

Family

ID=4225101

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19880810325 Expired - Lifetime EP0295204B1 (de) 1987-05-29 1988-05-24 Mehrkammerbehälter zur Aufbewahrung und nachfolgenden Mischung aktiver Komponenten

Country Status (7)

Country Link
US (1) US4997083A (de)
EP (1) EP0295204B1 (de)
JP (1) JPH07106755B2 (de)
AT (1) ATE65473T1 (de)
CH (1) CH686778A5 (de)
DE (1) DE3863849D1 (de)
ES (1) ES2024048B3 (de)

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0642550A4 (de) * 1992-05-29 1995-04-19
EP0623045A4 (en) * 1992-11-06 1996-04-17 Baxter Int Method for filtering a body fluid using rinse chamber bag.
EP0790051A3 (de) * 1996-02-14 1997-11-26 B. Braun Melsungen Ag Flexibler Kunststoffbehälter
WO1998010733A1 (en) * 1996-09-11 1998-03-19 Baxter International Inc. Containers and methods for storing and admixing medical solutions
WO1998016183A1 (en) 1996-10-11 1998-04-23 B. Braun Melsungen Ag Flexible plastic container with three chambers
WO1999027885A1 (en) * 1997-11-28 1999-06-10 Gambro Ab Multiple compartment container for medical solution
EP0541715B2 (de) † 1990-08-02 2004-06-16 B. Braun Medical Inc. Flexibler, mehrere abteilungen aufweisender behälter für medikamente
US6848234B2 (en) 2002-07-19 2005-02-01 Samsung Electronics, Co., Ltd. Sealing machine
WO2010111184A1 (en) * 2009-03-26 2010-09-30 Warsaw Orthopedic, Inc. Device to deliver magnesium in peg formulation
EP2091497A4 (de) * 2006-12-07 2014-03-26 Gambro Lundia Ab Behälter mit mehreren fächern
RU2554800C2 (ru) * 2010-05-10 2015-06-27 Б. Браун Мельзунген Аг Манипулирование гибким пакетом для содержания лекарственных препаратов.
RU2556472C2 (ru) * 2010-05-10 2015-07-10 Б. Браун Мельзунген Аг Форма
US9962896B2 (en) 2008-02-27 2018-05-08 Fenwal, Inc. Peelable seals including porous inserts
EP3673888A1 (de) * 2018-12-27 2020-07-01 Eurozyto GmbH Beutel zur bereitstellung eines medizinischen wirkstoffs und set mit beutel und überleitsystem
WO2026043974A1 (en) * 2024-08-21 2026-02-26 Genzyme Corporation Preparation assembly and method of preparing a liquid medicament

Families Citing this family (119)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0354644U (de) * 1989-09-29 1991-05-27
US5146840A (en) * 1989-11-22 1992-09-15 Heden-Team Ag Automatic baking apparatus and mixbag therefore
WO1992010100A1 (en) * 1990-12-13 1992-06-25 Heden-Team Ag Automatic baking apparatus and mixbag therefor
US5318540A (en) * 1990-04-02 1994-06-07 Pharmetrix Corporation Controlled release infusion device
US5492534A (en) * 1990-04-02 1996-02-20 Pharmetrix Corporation Controlled release portable pump
DE69126861T2 (de) * 1990-11-07 1998-02-26 Baxter Int Lösung zur aufbewahrung roter blutzellen
CA2099596A1 (en) * 1990-12-27 1992-06-28 Gregory E. Sancoff Closed system for iv site flush
US5207645A (en) * 1991-06-25 1993-05-04 Medication Delivery Devices Infusion pump, treatment fluid bag therefor, and method for the use thereof
SE9103395D0 (sv) * 1991-11-18 1991-11-18 Gambro Ab System med anvaendning av ensteril medicinsk loesning innehaallande glukos eller glukosliknande aemnen samt en loesning avsedd foer detta system
US5827820A (en) * 1992-04-06 1998-10-27 Baxter International Inc. Aqueous peritoneal dialysis solution
US5356709A (en) * 1992-05-14 1994-10-18 Baxter International, Inc. Non-PVC coextruded medical grade port tubing
DE4316938A1 (de) * 1992-05-26 1993-12-02 S I F Ra Societa Italiana Farm Flexibler Behälter für die Wäsche und zur wirksamen Einschaltung in Dialysekreisläufe und -filter
US6380163B1 (en) * 1992-12-22 2002-04-30 Baxter International Inc. Peritoneal dialysis solutions with polypeptides
NZ261517A (en) * 1993-01-19 1997-02-24 Baxter Int Multiple chamber container: openable valve in dividing seal
AU5637094A (en) 1993-03-16 1994-09-22 Clintec Nutrition Company Peelable seal and container having same
US5462526A (en) * 1993-09-15 1995-10-31 Mcgaw, Inc. Flexible, sterile container and method of making and using same
USD354220S (en) 1993-09-22 1995-01-10 Amoco Corporation Closed disposable package
DE4447626C5 (de) * 1994-03-29 2007-01-25 Fresenius Ag Medizinischer Mehrkammerbeutel
US5431174A (en) * 1994-04-04 1995-07-11 Via Medical Corporation Method of fluid delivery and collection
JP2692580B2 (ja) * 1994-05-06 1997-12-17 株式会社ニッショー 薬剤容器
ES2167434T3 (es) * 1994-05-11 2002-05-16 Baxter Int Sistema de recogida de sangre.
US5551557A (en) * 1994-10-25 1996-09-03 Convey, Inc. Efficient method and apparatus for establishing shelf-life of getters utilized within sealed enclosures
US7169547B2 (en) 1994-12-05 2007-01-30 New York Blood Center, Inc. High concentration white blood cells as a therapeutic product
US5789147A (en) * 1994-12-05 1998-08-04 New York Blood Center, Inc. Method for concentrating white cells from whole blood by adding a red cell sedimentation reagent to whole anticoagulated blood
US5643533A (en) * 1995-05-12 1997-07-01 Fishman; Yoram Method of packaged goods sterilization
SE510030C2 (sv) * 1995-08-08 1999-04-12 Gambro Ab Förfarande för blandning av steril medicinsk lösning samt behållare för utförande av förfarandet
JP2789448B2 (ja) * 1995-08-16 1998-08-20 株式会社新素材総合研究所 医療用容器及びその製造方法
SE9601348D0 (sv) * 1996-04-10 1996-04-10 Pharmacia Ab Improved containers for parenteral fluids
US6808675B1 (en) 1996-06-25 2004-10-26 Thermogenesis Corp. Freezing and thawing bag, mold, apparatus and method
US6146124A (en) 1996-06-25 2000-11-14 Thermogenesis Corp. Freezing and thawing bag, mold, apparatus and method
SE9602818D0 (sv) * 1996-07-19 1996-07-19 Pharmacia & Upjohn Ab Colored composition
US6213334B1 (en) * 1996-09-05 2001-04-10 Baxter International Inc Flexible, three-dimensional containers and methods for making them
CA2274787C (en) * 1996-12-13 2009-01-27 Norian Corporation Preparation, storage and administration of cements
JP4271733B2 (ja) * 1996-12-13 2009-06-03 ノリアン コーポレイション セメントの調製、保存、および投与
US6071262A (en) * 1997-10-20 2000-06-06 Okamoto; Rodney System for infusing intravenous nutrition solutions
US6491679B1 (en) 1997-10-20 2002-12-10 Rodney Okamoto System for infusing intravenous nutrition solutions
US6361642B1 (en) 1997-12-02 2002-03-26 Baxter International Inc. Heat and pressure-formed flexible containers
US6159192A (en) 1997-12-04 2000-12-12 Fowles; Thomas A. Sliding reconstitution device with seal
US6074366A (en) 1998-01-16 2000-06-13 Tandem Medical Inc. Medication delivery apparatus
TW367247B (en) * 1998-02-03 1999-08-21 Otsuka Pharma Co Ltd Storage container for Vitamin D solution and transfusion container
US6729369B2 (en) 1998-07-31 2004-05-04 Chata Biosystems, Inc. Vessel for containing/transporting a fluent substance
US7358505B2 (en) * 1998-09-15 2008-04-15 Baxter International Inc. Apparatus for fabricating a reconstitution assembly
US20050137566A1 (en) * 2003-12-23 2005-06-23 Fowles Thomas A. Sliding reconstitution device for a diluent container
US6022339A (en) 1998-09-15 2000-02-08 Baxter International Inc. Sliding reconstitution device for a diluent container
AR021220A1 (es) 1998-09-15 2002-07-03 Baxter Int DISPOSITIVO DE CONEXIoN PARA ESTABLECER UNA COMUNICACIoN FLUíDA ENTRE UN PRIMER RECIPIENTE Y UN SEGUNDO RECIPIENTE.
US7074216B2 (en) * 1998-09-15 2006-07-11 Baxter International Inc. Sliding reconstitution device for a diluent container
SE521219C2 (sv) * 1998-10-23 2003-10-14 Gambro Ab Metod och anordning för att reducera nedbrytning av värmekänsliga komponenter i medicinska substanser under värmesterilisering
US6565802B1 (en) * 1999-06-03 2003-05-20 Baxter International Inc. Apparatus, systems and methods for processing and treating a biological fluid with light
US7068361B2 (en) 1999-06-03 2006-06-27 Baxter International Apparatus, systems and methods for processing and treating a biological fluid with light
US7025877B1 (en) 1999-06-03 2006-04-11 Baxter International Inc. Processing set for processing and treating a biological fluid
US6364864B1 (en) 1999-06-03 2002-04-02 Baxter International Inc. Plastic containers having inner pouches and methods for making such containers
US7445756B2 (en) * 1999-06-03 2008-11-04 Fenwal, Inc. Fluid processing sets and organizers for the same
US6428518B1 (en) 1999-11-05 2002-08-06 Tandem Medical Medication delivery container
US6726655B1 (en) 1999-11-05 2004-04-27 Tandem Medical Medication delivery system
US20050194060A1 (en) * 2004-03-03 2005-09-08 Vincent Houwaert Peelable seal closure assembly
US7678097B1 (en) 1999-11-12 2010-03-16 Baxter International Inc. Containers and methods for manufacturing same
US6612769B2 (en) * 2000-12-13 2003-09-02 Innovative Properties Company Package and dispensing actuator for multiple-component compositions
JP3926166B2 (ja) * 2002-02-13 2007-06-06 東洋自動機株式会社 包装袋のシール方法及び充填及びシール済み包装袋
US8562583B2 (en) 2002-03-26 2013-10-22 Carmel Pharma Ab Method and assembly for fluid transfer and drug containment in an infusion system
US7867215B2 (en) * 2002-04-17 2011-01-11 Carmel Pharma Ab Method and device for fluid transfer in an infusion system
SE523001C2 (sv) * 2002-07-09 2004-03-23 Carmel Pharma Ab En kopplingsdel, en koppling, en infusionspåse, en infusionsanordning och ett förfarande för överföring av medicinska substanser
US7175614B2 (en) * 2002-10-17 2007-02-13 Baxter International Inc. Peelable seal
WO2004045754A1 (en) 2002-11-20 2004-06-03 Unilever N.V. Apparatus and method for mixing components
JP5148107B2 (ja) * 2003-01-21 2013-02-20 カルメル ファルマ アクチボラゲット 膜を突き刺すための針
US20040245144A1 (en) * 2003-06-03 2004-12-09 Hurst William E. Preformed mixing bag for dry powder, apparatus, method and system for using same
US20040245124A1 (en) * 2003-06-03 2004-12-09 Hurst William E. Preformed mixing bag for dry powder, apparatus, method and system for using same
US7641851B2 (en) * 2003-12-23 2010-01-05 Baxter International Inc. Method and apparatus for validation of sterilization process
US20050218154A1 (en) * 2004-03-24 2005-10-06 Selsby Adam B Low Profile Fluid Container
US9334098B1 (en) * 2004-03-26 2016-05-10 Kenneth D. Hughes Reactive materials packaging
WO2005117802A1 (en) * 2004-06-01 2005-12-15 Gambro Lundia Ab Container for medical solution
FR2871062B1 (fr) 2004-06-02 2006-09-08 Aguettant Soc Par Actions Simp Poche de perfusion avec rincage integre
JP4679838B2 (ja) * 2004-06-02 2011-05-11 株式会社細川洋行 医療用薬液容器
EP1621178A1 (de) * 2004-07-29 2006-02-01 Fresenius Kabi Deutschland GmbH Flexibler Beutel mit mehrere Kammern zum vermischen von Lösungen für medizinische Zwecke
EP1621177A1 (de) * 2004-07-29 2006-02-01 Fresenius Kabi Deutschland GmbH Medizinischer Behälter mit verbessertem lösbarem Dichtungselement
US20060093765A1 (en) * 2004-10-29 2006-05-04 Sealed Air Corporation (Us) Multi-compartment pouch having a frangible seal
US20070246379A1 (en) * 2006-04-19 2007-10-25 Rainer Kuenzel Flexible Pouch Beverage Package
US9004761B2 (en) 2006-05-01 2015-04-14 Baxter International Inc. Multiple chamber container with mistake proof administration system
WO2007136791A2 (en) * 2006-05-18 2007-11-29 Maej, Llc Delivery device with separate chambers connectable in fluid communication when ready for use, and related method
US20100047403A1 (en) * 2006-10-30 2010-02-25 Elizabeth Johnson Pouch container for food product
KR20140063908A (ko) * 2006-11-06 2014-05-27 아지노모토 가부시키가이샤 복실 용기
US7942860B2 (en) 2007-03-16 2011-05-17 Carmel Pharma Ab Piercing member protection device
US7975733B2 (en) * 2007-05-08 2011-07-12 Carmel Pharma Ab Fluid transfer device
US8657803B2 (en) 2007-06-13 2014-02-25 Carmel Pharma Ab Device for providing fluid to a receptacle
US8622985B2 (en) * 2007-06-13 2014-01-07 Carmel Pharma Ab Arrangement for use with a medical device
US8029747B2 (en) 2007-06-13 2011-10-04 Carmel Pharma Ab Pressure equalizing device, receptacle and method
NZ560646A (en) * 2007-08-14 2010-01-29 Bomac Research Ltd Treatment apparatus
US10398834B2 (en) 2007-08-30 2019-09-03 Carmel Pharma Ab Device, sealing member and fluid container
US8287513B2 (en) * 2007-09-11 2012-10-16 Carmel Pharma Ab Piercing member protection device
WO2009038505A1 (en) 2007-09-17 2009-03-26 Carmel Pharma Ab Bag connector
JP2008063008A (ja) * 2007-10-29 2008-03-21 Ajinomoto Co Inc 薬液容器
CN101903003A (zh) * 2007-12-27 2010-12-01 巴克斯特国际公司 多室容器
US8075550B2 (en) * 2008-07-01 2011-12-13 Carmel Pharma Ab Piercing member protection device
US8790330B2 (en) * 2008-12-15 2014-07-29 Carmel Pharma Ab Connection arrangement and method for connecting a medical device to the improved connection arrangement
US8523838B2 (en) * 2008-12-15 2013-09-03 Carmel Pharma Ab Connector device
DE102008063592B4 (de) 2008-12-18 2012-01-12 Dirk Schindelhauer Multifunktionaler Laborprozessbeutel für die Reinherstellung von Biomolekülen
US8056726B2 (en) * 2009-03-20 2011-11-15 CDO Technologies, Inc. Method and apparatus for repairing a surface defect
US11864553B2 (en) 2009-10-23 2024-01-09 Fenwal, Inc. Methods and systems for providing red blood cell products with reduced plasma
US8480646B2 (en) * 2009-11-20 2013-07-09 Carmel Pharma Ab Medical device connector
USD637713S1 (en) 2009-11-20 2011-05-10 Carmel Pharma Ab Medical device adaptor
USD653330S1 (en) * 2010-05-10 2012-01-31 B. Braun Melsungen Ag Flexible, multiple chamber storage container for medical use
EP2386283A1 (de) 2010-05-10 2011-11-16 B. Braun Melsungen AG Befüllen
USD653331S1 (en) * 2010-05-10 2012-01-31 B. Braun Melsungen Ag Flexible, multiple chamber storage container for medical use
USD653751S1 (en) * 2010-05-10 2012-02-07 B. Braun Melsungen Ag Flexible, multiple chamber storage container for medical use
USD653333S1 (en) * 2010-05-10 2012-01-31 B. Braun Melsungen Ag Flexible, multiple chamber storage container for medical use
US8162013B2 (en) 2010-05-21 2012-04-24 Tobias Rosenquist Connectors for fluid containers
US9168203B2 (en) 2010-05-21 2015-10-27 Carmel Pharma Ab Connectors for fluid containers
US20120024812A1 (en) * 2010-08-02 2012-02-02 Philip Andrew Underwood Water bottle with multiple drink dosage device
USD669260S1 (en) 2010-12-20 2012-10-23 Davidson Guy P Concealable beverage container
WO2012099898A2 (en) * 2011-01-17 2012-07-26 Aktivpak, Inc. Aseptic cartridge and dispenser arrangement
WO2012158973A2 (en) 2011-05-17 2012-11-22 Aktivpak, Inc. Filing system and methods for aseptic cartridge and dispenser arrangement
US20130269827A1 (en) * 2012-04-10 2013-10-17 John Sheridan Thomas, JR. Two compartment syringe accessible package and method of using and making the same
EP3016694B1 (de) 2013-07-05 2017-12-06 Gambro Lundia AB Verpackung von pulverförmigem material zur herstellung einer medizinischen lösung
US20150045725A1 (en) * 2013-08-12 2015-02-12 Vanderbilt University Insufflation and co2 delivery for minimally invasive procedures
DE102014202261A1 (de) * 2014-02-07 2015-08-27 Eurozyto Gmbh Behältnis und Set zur Bereitstellung parenteraler Nahrung
DK178893B1 (en) * 2015-07-05 2017-05-01 Dorte Dyrsborg Intravenous Bag
US10086988B2 (en) * 2016-04-08 2018-10-02 Katie Rose Grobman Configurable packet for controllable mixing and dispensing of condiments
US10689152B2 (en) * 2016-08-22 2020-06-23 James Alexander Corporation Dispenser and process
US10507165B2 (en) 2017-05-31 2019-12-17 Adienne Pharma & Biotech Sa Multi chamber flexible bag and methods of using same
CN107244488A (zh) * 2017-07-17 2017-10-13 东莞市科妍化妆品有限公司 一种双袋面膜袋及面膜使用方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH364073A (fr) * 1961-02-14 1962-08-31 Vifor Sa Récipient mélangeur
FR2255224A1 (de) * 1973-12-21 1975-07-18 Prenntzell Kurt
WO1983001569A1 (en) * 1981-11-09 1983-05-11 Baxter Travenol Lab Multiple chamber solution container including positive test for homogenous mixture
WO1983003539A1 (en) * 1982-04-06 1983-10-27 Baxter Travenol Lab Container for mixing a liquid and a solid
CH660868A5 (en) * 1984-10-05 1987-05-29 Vifor Sa Mixer container with cartridge

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3545671A (en) * 1967-02-14 1970-12-08 Eugene Ross Lab Inc Apparatus for and method of collecting,storing,separating and dispensing blood and blood components
US4298119A (en) * 1980-01-11 1981-11-03 Murray Michael L Multiple compartment containers
US4467588A (en) * 1982-04-06 1984-08-28 Baxter Travenol Laboratories, Inc. Separated packaging and sterile processing for liquid-powder mixing
US4458733A (en) * 1982-04-06 1984-07-10 Baxter Travenol Laboratories, Inc. Mixing apparatus
FR2532550B1 (fr) * 1982-09-02 1986-01-17 Synthelabo Biomedical Poches a usage medical, et en particulier destinees a l'alimentation parenterale
JPS5975059A (ja) * 1982-10-22 1984-04-27 テルモ株式会社 輸液容器
SE8306400L (sv) * 1983-01-24 1984-07-25 Bard Inc C R Blandningsforpackning med ett flertal fack
US4507114A (en) * 1983-10-21 1985-03-26 Baxter Travenol Laboratories, Inc. Multiple chamber container having leak detection compartment
US4528220A (en) * 1984-02-09 1985-07-09 Shell Oil Company Plastic bags for medical solutions and blood
US4608043A (en) * 1984-06-22 1986-08-26 Abbott Laboratories I.V. fluid storage and mixing system

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH364073A (fr) * 1961-02-14 1962-08-31 Vifor Sa Récipient mélangeur
FR2255224A1 (de) * 1973-12-21 1975-07-18 Prenntzell Kurt
WO1983001569A1 (en) * 1981-11-09 1983-05-11 Baxter Travenol Lab Multiple chamber solution container including positive test for homogenous mixture
WO1983003539A1 (en) * 1982-04-06 1983-10-27 Baxter Travenol Lab Container for mixing a liquid and a solid
CH660868A5 (en) * 1984-10-05 1987-05-29 Vifor Sa Mixer container with cartridge

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0541715B2 (de) † 1990-08-02 2004-06-16 B. Braun Medical Inc. Flexibler, mehrere abteilungen aufweisender behälter für medikamente
EP0642550A4 (de) * 1992-05-29 1995-04-19
EP0623045A4 (en) * 1992-11-06 1996-04-17 Baxter Int Method for filtering a body fluid using rinse chamber bag.
EP0790051A3 (de) * 1996-02-14 1997-11-26 B. Braun Melsungen Ag Flexibler Kunststoffbehälter
WO1998010733A1 (en) * 1996-09-11 1998-03-19 Baxter International Inc. Containers and methods for storing and admixing medical solutions
WO1998016183A1 (en) 1996-10-11 1998-04-23 B. Braun Melsungen Ag Flexible plastic container with three chambers
WO1999027885A1 (en) * 1997-11-28 1999-06-10 Gambro Ab Multiple compartment container for medical solution
US6848234B2 (en) 2002-07-19 2005-02-01 Samsung Electronics, Co., Ltd. Sealing machine
US9320680B2 (en) 2006-12-07 2016-04-26 Gambro Lundia Ab Multicompartment container
EP2091497A4 (de) * 2006-12-07 2014-03-26 Gambro Lundia Ab Behälter mit mehreren fächern
US9962896B2 (en) 2008-02-27 2018-05-08 Fenwal, Inc. Peelable seals including porous inserts
WO2010111184A1 (en) * 2009-03-26 2010-09-30 Warsaw Orthopedic, Inc. Device to deliver magnesium in peg formulation
US9078808B2 (en) 2009-03-26 2015-07-14 Warsaw Orthopedic, Inc. Device to deliver magnesium in PEG formulation
RU2556472C2 (ru) * 2010-05-10 2015-07-10 Б. Браун Мельзунген Аг Форма
RU2554800C2 (ru) * 2010-05-10 2015-06-27 Б. Браун Мельзунген Аг Манипулирование гибким пакетом для содержания лекарственных препаратов.
EP3673888A1 (de) * 2018-12-27 2020-07-01 Eurozyto GmbH Beutel zur bereitstellung eines medizinischen wirkstoffs und set mit beutel und überleitsystem
WO2026043974A1 (en) * 2024-08-21 2026-02-26 Genzyme Corporation Preparation assembly and method of preparing a liquid medicament

Also Published As

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EP0295204B1 (de) 1991-07-24
ATE65473T1 (de) 1991-08-15
JPH07106755B2 (ja) 1995-11-15
ES2024048B3 (es) 1992-02-16
CH686778A5 (fr) 1996-06-28
US4997083A (en) 1991-03-05
JPS63317481A (ja) 1988-12-26
DE3863849D1 (de) 1991-08-29

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