EP0354441A3 - Procédé de détermination colorimétrique d'analyse utilisant l'oxidation enzymatique - Google Patents

Procédé de détermination colorimétrique d'analyse utilisant l'oxidation enzymatique Download PDF

Info

Publication number
EP0354441A3
EP0354441A3 EP19890114143 EP89114143A EP0354441A3 EP 0354441 A3 EP0354441 A3 EP 0354441A3 EP 19890114143 EP19890114143 EP 19890114143 EP 89114143 A EP89114143 A EP 89114143A EP 0354441 A3 EP0354441 A3 EP 0354441A3
Authority
EP
European Patent Office
Prior art keywords
analyte
enzymatic
oxydation
colorimetric determination
electron acceptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP19890114143
Other languages
German (de)
English (en)
Other versions
EP0354441B1 (fr
EP0354441A2 (fr
Inventor
Joachim Dr. Hoenes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics GmbH, Boehringer Mannheim GmbH filed Critical Roche Diagnostics GmbH
Publication of EP0354441A2 publication Critical patent/EP0354441A2/fr
Publication of EP0354441A3 publication Critical patent/EP0354441A3/fr
Application granted granted Critical
Publication of EP0354441B1 publication Critical patent/EP0354441B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01RELECTRICALLY-CONDUCTIVE CONNECTIONS; STRUCTURAL ASSOCIATIONS OF A PLURALITY OF MUTUALLY-INSULATED ELECTRICAL CONNECTING ELEMENTS; COUPLING DEVICES; CURRENT COLLECTORS
    • H01R13/00Details of coupling devices of the kinds covered by groups H01R12/70 or H01R24/00 - H01R33/00
    • H01R13/73Means for mounting coupling parts to apparatus or structures, e.g. to a wall
    • HELECTRICITY
    • H05ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05KPRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
    • H05K7/00Constructional details common to different types of electric apparatus
    • H05K7/02Arrangements of circuit components or wiring on supporting structure
    • H05K7/12Resilient or clamping means for holding component to structure
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01RELECTRICALLY-CONDUCTIVE CONNECTIONS; STRUCTURAL ASSOCIATIONS OF A PLURALITY OF MUTUALLY-INSULATED ELECTRICAL CONNECTING ELEMENTS; COUPLING DEVICES; CURRENT COLLECTORS
    • H01R13/00Details of coupling devices of the kinds covered by groups H01R12/70 or H01R24/00 - H01R33/00
    • H01R13/46Bases; Cases

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
EP89114143A 1988-08-09 1989-08-01 Procédé de détermination colorimétrique d'analyse utilisant l'oxidation enzymatique Expired - Lifetime EP0354441B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3826922 1988-08-09
DE3826922A DE3826922A1 (de) 1988-08-09 1988-08-09 Verfahren zur kolorimetrischen bestimmung eines analyten mittels enzymatischer oxidation

Publications (3)

Publication Number Publication Date
EP0354441A2 EP0354441A2 (fr) 1990-02-14
EP0354441A3 true EP0354441A3 (fr) 1992-04-08
EP0354441B1 EP0354441B1 (fr) 1995-05-17

Family

ID=6360464

Family Applications (1)

Application Number Title Priority Date Filing Date
EP89114143A Expired - Lifetime EP0354441B1 (fr) 1988-08-09 1989-08-01 Procédé de détermination colorimétrique d'analyse utilisant l'oxidation enzymatique

Country Status (12)

Country Link
US (2) US5206147A (fr)
EP (1) EP0354441B1 (fr)
JP (1) JPH0687793B2 (fr)
KR (1) KR920001449B1 (fr)
AT (1) ATE122726T1 (fr)
AU (1) AU614405B2 (fr)
CA (1) CA1339058C (fr)
DD (1) DD284050A5 (fr)
DE (2) DE3826922A1 (fr)
ES (1) ES2074457T3 (fr)
HK (1) HK173796A (fr)
RU (1) RU2015513C1 (fr)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3940010A1 (de) * 1989-12-02 1991-06-06 Boehringer Mannheim Gmbh Verwendung eines schwer loeslichen salzes einer heteropolysaeure zur bestimmung eines analyts, entsprechendes bestimmungsverfahren sowie hierfuer geeignetes mittel
DE4003194A1 (de) * 1990-02-03 1991-08-08 Boehringer Mannheim Gmbh Verfahren und sensorelektrodensystem zur elektrochemischen bestimmung eines analyts oder einer oxidoreduktase sowie verwendung hierfuer geeigneter verbindungen
ES2141172T3 (es) * 1992-09-28 2000-03-16 Roche Diagnostics Corp Reactivo estable para sistemas indicadores de complejos de ion ferrico.
DE4311460A1 (de) * 1993-04-08 1994-10-13 Boehringer Mannheim Gmbh Verfahren zur kolorimetrischen Bestimmung eines Analyten mittels Benzylalkoholdehydrogenase und einem chromogenen Redoxindikator
DE4311464A1 (de) * 1993-04-08 1994-10-13 Boehringer Mannheim Gmbh Verfahren zur kolorimetrischen Bestimmung eines Analyten mit einer PQQ-abhängigen Dehydrogenase
US5620579A (en) * 1995-05-05 1997-04-15 Bayer Corporation Apparatus for reduction of bias in amperometric sensors
US5989845A (en) 1996-04-05 1999-11-23 Mercury Diagnostics, Inc. Diagnostic compositions and devices utilizing same
US5776719A (en) * 1997-07-07 1998-07-07 Mercury Diagnostics, Inc. Diagnostic compositions and devices utilizing same
US6040151A (en) * 1998-03-10 2000-03-21 Mercury Diagnostics, Inc. Diagnostic compositions and devices utilizing same
IL121279A (en) * 1996-07-16 2001-05-20 Roche Diagnostics Gmbh An analytical system with means for testing samples with too small volumes
DE19628562A1 (de) 1996-07-16 1998-01-22 Boehringer Mannheim Gmbh Analysesystem mit Mitteln zur Erkennung von Unterdosierungen
DE69809391T2 (de) 1997-02-06 2003-07-10 Therasense, Inc. Kleinvolumiger sensor zur in-vitro bestimmung
US6391645B1 (en) 1997-05-12 2002-05-21 Bayer Corporation Method and apparatus for correcting ambient temperature effect in biosensors
US6428974B1 (en) * 1998-04-03 2002-08-06 Kanto Kagaku Kabushiki Kaisha Microplate for drug susceptibility testing containing a drug, a color reagent, and color suppressant
US6030802A (en) * 1998-05-29 2000-02-29 Roche Diagnostics Corporation Liquid reagent set for L-lactate determination
US5902731A (en) * 1998-09-28 1999-05-11 Lifescan, Inc. Diagnostics based on tetrazolium compounds
US6656697B1 (en) * 1998-09-28 2003-12-02 Lifescan, Inc. Diagnostics based on tetrazolium compounds
JP3694424B2 (ja) 1998-09-29 2005-09-14 松下電器産業株式会社 グルコースセンサ
US6338790B1 (en) 1998-10-08 2002-01-15 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
DE19945828B4 (de) 1999-09-24 2011-06-01 Roche Diagnostics Gmbh Analysenelement und Verfahren zur Bestimmung eines Analyten in Flüssigkeit
US7005048B1 (en) 1999-10-05 2006-02-28 Matsushita Electric Industrial Co., Ltd. Glucose sensor
DE10001529A1 (de) * 2000-01-15 2001-07-19 Roche Diagnostics Gmbh Stabilisierte Coenzym-Lösungen und deren Verwendung zur Bestimmung von Dehydrogenasen bzw. deren Substrate
US6420128B1 (en) * 2000-09-12 2002-07-16 Lifescan, Inc. Test strips for detecting the presence of a reduced cofactor in a sample and method for using the same
EP1416851B1 (fr) * 2001-06-08 2006-08-09 Roche Diagnostics GmbH Dispositif de prelevement de liquide corporel et cassette a support d'essai destinee a etre utilisee avec ledit dispositif
US7163616B2 (en) * 2001-09-14 2007-01-16 Bayer Corporation Reagents and methods for detecting analytes, and devices comprising reagents for detecting analytes
US6982152B2 (en) * 2002-04-17 2006-01-03 Promega Corporation Cytotoxicity assay
US6759190B2 (en) * 2002-06-15 2004-07-06 Acon Laboratories, Inc. Test strip for detection of analyte and methods of use
DE10248555B4 (de) * 2002-10-18 2004-12-02 Roche Diagnostics Gmbh Verfahren und Analysesystem zur Ermittlung der Konzentration eines Analyten in einer Probe, die aus dem Analyten und der Probenmatrix besteht und Testelement dafür
US7572237B2 (en) 2002-11-06 2009-08-11 Abbott Diabetes Care Inc. Automatic biological analyte testing meter with integrated lancing device and methods of use
DE10304448A1 (de) 2003-02-04 2004-08-12 Roche Diagnostics Gmbh Fluorimetrische Bestimmung von Analyten durch Amin-N-Oxide als Redoxindikatoren
DE10346863A1 (de) * 2003-10-09 2005-05-04 Roche Diagnostics Gmbh On-Board-Kontrolle für Analyseelemente
JP4839219B2 (ja) 2003-10-24 2011-12-21 バイエル・ヘルスケア・エルエルシー 酵素的電気化学的バイオセンサ
CN1914331A (zh) * 2004-02-06 2007-02-14 拜尔健康护理有限责任公司 作为生物传感器的内部参照的可氧化种类和使用方法
BRPI0509296A (pt) 2004-03-31 2007-09-18 Bayer Healthcare Llc método e aparelho para implementar funções corretivas baseadas em limiares para biossensores
US20060024835A1 (en) * 2004-07-30 2006-02-02 Matzinger David P Analytical test strip with control zone
DE602006015295D1 (de) * 2005-04-04 2010-08-19 Facet Technologies Llc Lanzettenvorrichtung mit schmalem profil
WO2007013915A1 (fr) 2005-07-20 2007-02-01 Bayer Healthcare Llc Amperometrie a declenchement periodique
WO2007040913A1 (fr) 2005-09-30 2007-04-12 Bayer Healthcare Llc Voltamperometrie commandee
US7955484B2 (en) * 2005-12-14 2011-06-07 Nova Biomedical Corporation Glucose biosensor and method
DE102006043718B4 (de) 2006-09-18 2014-12-31 Alexander Adlassnig Bestimmung von Wasserstoffperoxidkonzentrationen
EP3543348B1 (fr) 2006-09-22 2020-11-18 Ascensia Diabetes Care Holdings AG Système de biocapteur présentant une stabilité améliorée et une fonction de mesure d'hématocrite
EP3753481B1 (fr) 2006-10-24 2024-07-17 Ascensia Diabetes Care Holdings AG Dispositif pour amperométrie de decroissance transitoire
EP1964927A1 (fr) * 2007-02-27 2008-09-03 F. Hoffmann-La Roche AG Quinone en tant que médiateurs pour tests photométriques
CA2716603A1 (fr) * 2007-03-05 2009-09-12 Advanced Liquid Logic, Inc. Dosages sur gouttelettes du peroxyde d'hydrogene
WO2009076302A1 (fr) 2007-12-10 2009-06-18 Bayer Healthcare Llc Marqueurs de contrôle pour la détection automatique d'une solution de contrôle et procédés d'utilisation
JP5856371B2 (ja) 2007-12-10 2016-02-09 バイエル・ヘルスケア・エルエルシーBayer HealthCareLLC 分析対象物を検出するための試薬及び方法
EP3187866B1 (fr) 2007-12-10 2019-04-17 Ascensia Diabetes Care Holdings AG Capteur d'analyse électrochimique
WO2009076268A1 (fr) * 2007-12-10 2009-06-18 Bayer Healthcare Llc Procédé de fabrication de médiateur de 3-phénylimino-3h-phénothiazine ou de 3-phénylimino-3h-phénoxazine
US20090219509A1 (en) * 2008-02-29 2009-09-03 Hiroshi Nomura Optical sensor with enhanced reflectance
US8008068B2 (en) * 2008-02-29 2011-08-30 Light Pointe Medical, Inc. Nonhemolytic optical sensor with enhanced reflectance
US8008037B2 (en) 2008-03-27 2011-08-30 Roche Diagnostics Operations, Inc. Matrix composition with alkylphenazine quaternary salt and a nitrosoaniline
WO2011012754A2 (fr) 2009-07-30 2011-02-03 Fundacion Cidetec Détecteur électrochimique pour la détection d'analytes dans des milieux liquides
EP2287295A1 (fr) 2009-08-03 2011-02-23 Roche Diagnostics GmbH Muté fructosyl oxydase d'acide aminé
EP2281900A1 (fr) 2009-08-03 2011-02-09 Roche Diagnostics GmbH Fructosyl-oxydase peptidique et capteur pour la détermination des protéines glycées
JP6055236B2 (ja) * 2011-08-17 2016-12-27 株式会社三和化学研究所 測定方法
EP2562251B1 (fr) 2011-08-25 2016-08-17 Roche Diagnostics GmbH Oxydase de cholestérol
WO2013026575A2 (fr) 2011-08-25 2013-02-28 Roche Diagnostics Gmbh Glucose oxydase
KR101609083B1 (ko) * 2011-09-28 2016-04-04 에프. 호프만-라 로슈 아게 아조 매개체
US9572922B2 (en) 2012-12-21 2017-02-21 Larry Leonard Inventive diabetic systems, tools, kits, and supplies for better diabetic living and mobility
KR101728597B1 (ko) 2012-04-19 2017-04-19 에프. 호프만-라 로슈 아게 혈액 내 분석물 농도를 결정하는 방법 및 디바이스
CN104870982B (zh) 2012-12-20 2019-02-15 霍夫曼-拉罗奇有限公司 用于评估医学测量曲线的方法
KR101750638B1 (ko) 2012-12-20 2017-06-23 에프. 호프만-라 로슈 아게 체액의 샘플을 분석하는 방법
JP6427110B2 (ja) 2013-01-28 2018-11-21 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト アスペルギルスニガー由来の新規グルコース酸化酵素
EP2781919A1 (fr) 2013-03-19 2014-09-24 Roche Diagniostics GmbH Procédé/dispositif permettant de générer une valeur corrigée de concentration d'un analyte dans un échantillon d'un fluide corporel
EP2796547B1 (fr) 2013-04-24 2016-09-14 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Nouveaux variants d'oxydase de glucose
EP3406732B1 (fr) * 2016-01-22 2020-11-04 National Agriculture and Food Research Organization Procédé de mesure d'activité d'oxydoréductase
CA3035874C (fr) 2016-10-05 2025-09-09 F. Hoffmann-La Roche Ag Reactifs de detection et agencements d'electrodes pour elements de test de diagnostic multi-analytes, ainsi que leurs procedes d'utilisation
EP3339431A1 (fr) 2016-12-22 2018-06-27 Roche Diabetes Care GmbH Variantes de glucose déshydrogénase à propriétés améliorées
DE102017208461A1 (de) 2017-05-18 2018-11-22 Diabetes.Online Ag Multianalytmessung
EP3759231B1 (fr) 2018-02-28 2023-10-18 F. Hoffmann-La Roche AG Revêtement de biocompatibilité pour la mesure continue d'analytes
JPWO2020122231A1 (ja) 2018-12-13 2021-10-21 キッコーマン株式会社 エタノールアミンリン酸の定量方法、定量用のオキシドレダクターゼ、定量用組成物、定量用キット及び定量用センサー
KR102178443B1 (ko) * 2018-12-17 2020-11-13 주식회사 포스코 글로우 방전 광학 방출 분광법의 다변량 분석을 이용한 철강 표면 산화철의 정량 분석 방법
US12116610B2 (en) 2021-01-26 2024-10-15 The University Of North Carolina At Chapel Hill Glycerol 3-phosphate oxidase mutants, compositions, devices, kits and uses thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105800A (en) * 1976-07-26 1978-08-08 Board Of Regents For Education Of The State Of Rhode Island Immobilized enzyme method to assess fish quality
EP0120440A2 (fr) * 1983-03-25 1984-10-03 Roche Diagnostics GmbH Glycérol déshydrogénase NAD(P)-indépendante, procédé pour sa production ainsi que son application dans le dosage de glycérine et de triglycérides
EP0296481A2 (fr) * 1987-06-20 1988-12-28 Drägerwerk Aktiengesellschaft Procédé de détection de matière gazeuse au moyen d'une réaction redox enzymatique
DE3820404A1 (de) * 1987-06-15 1988-12-29 Toyo Boseki Pyruvat-dehydrogenase und ihre verwendung in einem analytischen verfahren

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4645760A (en) * 1982-07-30 1987-02-24 Health Research Inc. Activated aminoglycosides and aminoglycoside-aminocyclitols pharmaceutical compositions and method of use
AU1469983A (en) * 1983-05-19 1984-11-22 Imperial Chemical Industries Plc Glucose determination using glucose d.h. and reducible cpd to change e.m. radiation
US4629689A (en) * 1984-08-29 1986-12-16 Allied Corporation Binding assay with amplified read-out and gas-phase detection
JPS62239999A (ja) * 1986-04-11 1987-10-20 Arinobu Fujimura Nad(p)hの半定量法
US5000815A (en) * 1988-12-19 1991-03-19 Ncr Corporation Apparatus for applying a correction sticker to a document

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105800A (en) * 1976-07-26 1978-08-08 Board Of Regents For Education Of The State Of Rhode Island Immobilized enzyme method to assess fish quality
EP0120440A2 (fr) * 1983-03-25 1984-10-03 Roche Diagnostics GmbH Glycérol déshydrogénase NAD(P)-indépendante, procédé pour sa production ainsi que son application dans le dosage de glycérine et de triglycérides
DE3820404A1 (de) * 1987-06-15 1988-12-29 Toyo Boseki Pyruvat-dehydrogenase und ihre verwendung in einem analytischen verfahren
EP0296481A2 (fr) * 1987-06-20 1988-12-28 Drägerwerk Aktiengesellschaft Procédé de détection de matière gazeuse au moyen d'une réaction redox enzymatique

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE WPIL (DERWENT), Abstract No. 87-062511DW8709; & JP-A-62 019 099 (SAPPORO BREWERIES) 27.01.1987. *

Also Published As

Publication number Publication date
AU3922289A (en) 1990-02-15
RU2015513C1 (ru) 1994-06-30
ATE122726T1 (de) 1995-06-15
DE3826922A1 (de) 1990-02-22
ES2074457T3 (es) 1995-09-16
US5206147A (en) 1993-04-27
EP0354441B1 (fr) 1995-05-17
US5334508A (en) 1994-08-02
DE58909232D1 (de) 1995-06-22
EP0354441A2 (fr) 1990-02-14
KR900003378A (ko) 1990-03-26
JPH0687793B2 (ja) 1994-11-09
AU614405B2 (en) 1991-08-29
KR920001449B1 (ko) 1992-02-14
HK173796A (en) 1996-09-20
DD284050A5 (de) 1990-10-31
JPH02174695A (ja) 1990-07-06
CA1339058C (fr) 1997-07-29

Similar Documents

Publication Publication Date Title
EP0354441A3 (fr) Procédé de détermination colorimétrique d'analyse utilisant l'oxidation enzymatique
EP1484604A3 (fr) Procédé de mesure de la concentration de NOx dans un gaz
EP0901018A3 (fr) Procédé de mesure quantitative d'un substrate
EP0741186A3 (fr) Procédé et dispositif pour la réduction des erreurs asymétriques dans des capteurs ampèremétriques
DE2833612A1 (de) Mittel und verfahren zur bestimmung von wasserstoffperoxyd
ATE27967T1 (de) Loesliche leber-uricase, verfahren zu ihrer herstellung und verwendung.
DE03250935T1 (de) Capteur electrochimique pour la detection de monoxyde de carbone
DE3239236A1 (de) Verfahren zur quantitativen bestimmung von physiologischen komponenten in biologischen fluessigkeiten oder gasen
ATE266030T1 (de) 1,4,7,10-tetraazabicyclo(8.2.2)tetradecan-2-on, verfahren zu ihrer herstellung und ihrer verwendung für die herstellung von tetraazamacrocyclen
ATE11569T1 (de) Zusammensetzung, pruefvorrichtung und verfahren zu ihrer herstellung und verfahren zur bestimmung eines stoffes in einer fluessigkeit.
ATE171220T1 (de) Verfahren zur kolorimetrischen bestimmung eines analyten mit einer pqq-abhängigen dehydrogenase
DE69431590T2 (de) In der anaerobischen bestimmung von analyten verwendbare zusammensetzungen
EP0356418A3 (fr) Procédé de détermination de la concentration d'un substrat d'enzyme et détecteur pour sa mise en oeuvre
DE3885048D1 (de) Testzusammensetzung, Vorrichtung und Verfahren zur visuellen Bestimmung von Wasserstoffperoxyd.
DE1498901A1 (de) Diagnostisches Mittel und Verfahren zum Nachweis bzw. zur Bestimmung von Harnsaeure im Blut
DE2264847A1 (de) Verfahren und reagenz zur bestimmung von cholesterin
DE3851635T2 (de) Testsatz und verfahren zur bestimmung von aniliden.
TW370616B (en) A method for quantitative determination of bilirubin and the reagent composition thereof
EP1101823A3 (fr) Procédé de préparation de dérivés d'indigo et colorants pour des fibres kératiniques qui les contiennent
DE10319295A1 (de) Verfahren zur Bestimmung der Glucosekonzentration im Blut
ATE94210T1 (de) Verfahren zur herstellung von glyoxylsaeure durch enzymatische oxydation von glykolsaeure.
CA2024052A1 (fr) Methode enzymatique pour la mesure de concentrations d'analytes
ATE311473T1 (de) Verfahren zum nachweis der löslichen guanylatzyklase
EP1003030A3 (fr) Procédé et transducteur pour la détermination de la teneur en oxygène d'un gaz
DE60325727D1 (de) Testverfahren mit einer oxidations-/reduktionsreaktion mit formazan

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19890808

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE CH DE ES FR GB GR IT LI LU NL SE

PUAL Search report despatched

Free format text: ORIGINAL CODE: 0009013

AK Designated contracting states

Kind code of ref document: A3

Designated state(s): AT BE CH DE ES FR GB GR IT LI LU NL SE

17Q First examination report despatched

Effective date: 19930813

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AT BE CH DE ES FR GB GR IT LI LU NL SE

REF Corresponds to:

Ref document number: 122726

Country of ref document: AT

Date of ref document: 19950615

Kind code of ref document: T

REF Corresponds to:

Ref document number: 58909232

Country of ref document: DE

Date of ref document: 19950622

ITF It: translation for a ep patent filed
ET Fr: translation filed
REG Reference to a national code

Ref country code: GR

Ref legal event code: FG4A

Free format text: 3016676

GBT Gb: translation of ep patent filed (gb section 77(6)(a)/1977)

Effective date: 19950807

REG Reference to a national code

Ref country code: ES

Ref legal event code: FG2A

Ref document number: 2074457

Country of ref document: ES

Kind code of ref document: T3

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

26N No opposition filed
REG Reference to a national code

Ref country code: GB

Ref legal event code: IF02

REG Reference to a national code

Ref country code: CH

Ref legal event code: PFA

Owner name: BOEHRINGER MANNHEIM GMBH

Free format text: BOEHRINGER MANNHEIM GMBH#SANDHOFERSTRASSE 112-132 POSTFACH 31 01 20#D-68298 MANNHEIM (DE) -TRANSFER TO- BOEHRINGER MANNHEIM GMBH#SANDHOFERSTRASSE 112-132 POSTFACH 31 01 20#D-68298 MANNHEIM (DE)

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: CH

Payment date: 20080708

Year of fee payment: 20

Ref country code: DE

Payment date: 20080829

Year of fee payment: 20

Ref country code: NL

Payment date: 20080715

Year of fee payment: 20

Ref country code: ES

Payment date: 20080806

Year of fee payment: 20

Ref country code: LU

Payment date: 20080731

Year of fee payment: 20

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: AT

Payment date: 20080708

Year of fee payment: 20

Ref country code: IT

Payment date: 20080814

Year of fee payment: 20

Ref country code: FR

Payment date: 20080807

Year of fee payment: 20

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20080708

Year of fee payment: 20

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: SE

Payment date: 20080808

Year of fee payment: 20

Ref country code: BE

Payment date: 20080828

Year of fee payment: 20

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GR

Payment date: 20080704

Year of fee payment: 20

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

REG Reference to a national code

Ref country code: GB

Ref legal event code: PE20

Expiry date: 20090731

BE20 Be: patent expired

Owner name: *BOEHRINGER MANNHEIM G.M.B.H.

Effective date: 20090801

NLV7 Nl: ceased due to reaching the maximum lifetime of a patent

Effective date: 20090801

EUG Se: european patent has lapsed
REG Reference to a national code

Ref country code: ES

Ref legal event code: FD2A

Effective date: 20090803

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GB

Free format text: LAPSE BECAUSE OF EXPIRATION OF PROTECTION

Effective date: 20090731

Ref country code: NL

Free format text: LAPSE BECAUSE OF EXPIRATION OF PROTECTION

Effective date: 20090801

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: ES

Free format text: LAPSE BECAUSE OF EXPIRATION OF PROTECTION

Effective date: 20090803