EP0445218A4 - Neural cell transplantation - Google Patents

Neural cell transplantation

Info

Publication number: EP0445218A4
Authority: EP; European Patent Office
Prior art keywords: cells; neuroactive; cell transplantation; neural cell; release
Prior art date: 1988-11-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP19900901107

Other languages

English (en)

French (fr)

Other versions

EP0445218A1 (en

Inventor

Dominic M. Lam

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Baylor College of Medicine

Original Assignee

Baylor College of Medicine

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-11-23

Filing date

1989-10-11

Publication date

1991-11-13

1989-10-11 Application filed by Baylor College of Medicine filed Critical Baylor College of Medicine

1991-09-11 Publication of EP0445218A1 publication Critical patent/EP0445218A1/en

1991-11-13 Publication of EP0445218A4 publication Critical patent/EP0445218A4/en

Status Withdrawn legal-status Critical Current

Links

210000003061 neural cell Anatomy 0.000 title 1
238000002054 transplantation Methods 0.000 title 1
239000000126 substance Substances 0.000 abstract 4
210000003169 central nervous system Anatomy 0.000 abstract 2
238000004519 manufacturing process Methods 0.000 abstract 2
230000001270 agonistic effect Effects 0.000 abstract 1
230000003042 antagnostic effect Effects 0.000 abstract 1
230000002950 deficient Effects 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
230000001939 inductive effect Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
- C12Y114/13—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with NADH or NADPH as one donor, and incorporation of one atom of oxygen (1.14.13)
- C12Y114/13041—Tyrosine N-monooxygenase (1.14.13.41)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
- C12Y114/16—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with reduced pteridine as one donor, and incorporation of one atom of oxygen (1.14.16)
- C12Y114/16002—Tyrosine 3-monooxygenase (1.14.16.2)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
General Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
General Health & Medical Sciences (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Microbiology (AREA)
Biophysics (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Medicinal Chemistry (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Prostheses (AREA)

EP19900901107 1988-11-23 1989-10-11 Neural cell transplantation Withdrawn EP0445218A4 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US27528388A	1988-11-23	1988-11-23
US275283		1988-11-23

Publications (2)

Publication Number	Publication Date
EP0445218A1 EP0445218A1 (en)	1991-09-11
EP0445218A4 true EP0445218A4 (en)	1991-11-13

Family

ID=23051627

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP19900901107 Withdrawn EP0445218A4 (en)	1988-11-23	1989-10-11	Neural cell transplantation

Country Status (4)

Country	Link
EP (1)	EP0445218A4 (ja)
JP (1)	JPH04501960A (ja)
AU (1)	AU4669189A (ja)
WO (1)	WO1990005781A1 (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0669987B1 (en) *	1992-09-25	2008-08-13	Aventis Pharma S.A.	Adenovirus vectors for the transfer of foreign genes into cells of the central nervous system, particularly in brain
US5753491A (en) *	1993-04-13	1998-05-19	Us Health	Use of neuro-derived fetal cell lines for transplantation therapy
JPH08509215A (ja) *	1993-04-13	1996-10-01	アメリカ合衆国	移植治療のための神経由来胎児セルラインの使用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1989009816A1 (en) *	1988-04-12	1989-10-19	Massachusetts Institute Of Technology	Method for manipulation of the cell types of eukaryotes

1989
- 1989-10-11 WO PCT/US1989/004569 patent/WO1990005781A1/en not_active Ceased
- 1989-10-11 JP JP2501176A patent/JPH04501960A/ja active Pending
- 1989-10-11 AU AU46691/89A patent/AU4669189A/en not_active Abandoned
- 1989-10-11 EP EP19900901107 patent/EP0445218A4/en not_active Withdrawn

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1989009816A1 (en) *	1988-04-12	1989-10-19	Massachusetts Institute Of Technology	Method for manipulation of the cell types of eukaryotes

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BIOCHEMISTRY, vol. 26, 1987, pages 5208-5212, American Chemical Society; E.R. BROWN et al.: "Organization of evolution of the rat tyrosine hydroxylase gene" *
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, USA, vol. 83, July 1986, pages 4794-4798; J.T. HOLT et al.: "Inducible production of c-fos antisense RNA inhibits 3T3 cell proliferation" *
See also references of WO9005781A1 *

Also Published As

Publication number	Publication date
EP0445218A1 (en)	1991-09-11
JPH04501960A (ja)	1992-04-09
WO1990005781A1 (en)	1990-05-31
AU4669189A (en)	1990-06-12

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Legal Events

Date	Code	Title	Description
1991-07-26	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1991-09-11	17P	Request for examination filed	Effective date: 19910522
1991-09-11	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE FR GB IT LI LU NL SE
1991-11-13	A4	Supplementary search report drawn up and despatched	Effective date: 19910926
1991-11-13	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE FR GB IT LI LU NL SE
1992-06-15	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
1992-08-05	18D	Application deemed to be withdrawn	Effective date: 19911212